CS2008 WK 5 Experiments I Lecture

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    CS2008 WK5:

    Experimental Design IDr. Christopher L. Cummings

    [email protected]

    Telephone: 6316 2916Office: Room #03-43

    Office hours: after class & by appointment

    1CS 2008: Experimental Design I

    mailto:[email protected]:[email protected]
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    First organized procedures as early as thethirteenth century in Greece.

    More formally, the experimental methodreceived its greatest impetus from the scientificadvances of the 16thand 17thcenturies.

    Allowed Sir Isaac Newton (1643-1727) toproclaim the qualities of bodies are only

    known to us by experiments

    History of experimentation

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    Vitamin C

    Scurvy

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    Sir James Lind (1716-1799)

    Scottish physician and thepioneer of naval hygiene.

    Conducted one of the firstdocumented clinical trial(experiment) in 1747.

    Sought a cure for scurvy,but he didnt know whatwould cure it.

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    ConditionsEach received the same typical

    naval diet (bread, butter, beans, & beer)Group 1: Quart of cider

    Group 2: 25 drops of vitriol (sulfuric acid)

    Group 3: 6 spoonfuls of vinegar

    Group 4: litre of seawater

    Group 5: 2 oranges and 1 lemon

    Group 6: Spicy pepper paste and litre of barley

    water

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    James Lind(17161799)

    Condition 5 stopped after 6 days of treatment whenthey ran out of fruit, but by then

    the most sudden and visible good effects were

    perceived from the use of the oranges andlemons; one of those who had taken them, being

    at the end of six days fit for duty.

    A treatise of the scurvy, 1753

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    Which textbook improves student

    learning the greatest?

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    Simple Design

    Dependent variable: Degree of student learning.

    Independent variable: Textbook given tostudents

    Condition A: Textbook A

    Condition B: Textbook B

    Condition C: Textbook C

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    19thand 20thcentury classical experimentation Practice of holding everything constant except the

    one variable under consideration.

    Move to the modern: 1935: Sir Ronald A. Fishers The Design of Experiments

    Experience carefully planned in advance

    Not controlling all potential variables, but rather

    manipulating levels or amounts of selected independentvariables in order to examine their influence on dependentvariables.

    Classicvs Modern Experiments

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    Why Do We Need Experimental Design?

    VariabilityWewouldnt need experimental design if:

    If all units (students, teachers, & schools) were

    identical, and If all units responded identically to treatments.

    We need experimental design to control

    variability so that the effects of our independentvariable of interest can be isolated and observed

    on the dependent variable.

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    Non-experimental methods have greaterdifficulty in assessing nomothetic causation.

    How do you know that the independent variable

    caused some change in the dependent?

    Experiments provide much greater control overvariables.

    Typically has better external validity than non-experimental research.

    Advantages of Experimental-methods

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    Vital concepts for experimental approaches:

    Manipulation

    Control

    Basics

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    Manipulation of the Independent Variable is keyto experimentation.

    manipulate IV and then observe changes in the

    DV for conditions and compare results.

    What variable are we manipulating when

    we conduct experiments?

    Condition

    1

    Independ

    ent

    Variable

    Condition

    2

    Dependent

    Variable

    Dependent

    Variable

    CompareResults

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    Influence of quantity of water

    on grass growth.

    Water

    Hi

    Quantityof

    water

    Water

    Low

    Grass growth

    in cm

    Grass growth

    in cm

    CompareResults

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    In the scientific method, control allows forcomparison between concepts.

    In this case, we often look at concepts as

    varying dimensions/levels of IVs.

    Controlling variables and attributes in theexperimental setting and data so that adequatecomparative conclusions can be reached.

    Control

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    Control groups In designed experiments, we separate research subjects into experimental

    groups (conditions).

    Experimental groups/Conditions: groups that receive some form ofcontrolled stimulus.

    Control group Group of participants to whom no experimental stimulus I

    administered but who should resemble the experimental group in allother respects. Comparison of the control group to the experimentalgroup(s) demonstrates the effect of the stimulus.

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    3 types of control

    Experimental design controls backgroundvariability so that systematic effects oftreatments can be observed.

    1. Control by matching

    2. Control by randomization

    3. Control by statistical adjustment

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    Control by Matching

    Some sources of variation may be eliminated by matching

    Eliminating genetic variationCompare animals from the same litter of mice

    Eliminating district or school effectsCompare students within districts or schools

    However matching is limited

    matching is only possible on observablecharacteristics perfect matching is never possible matching inherently limits generalizability by removing (possibly

    desired) variation

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    Control by Matching

    Matching ensures that groups compared are alikeon specific known and observablecharacteristics (inprinciple, everything we have thought of)

    Wouldnt it be great if there were

    a method of making groups alike

    on not only everything we have

    thought of, but everything wedidnt think of too?

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    Assigning of experimentalsubjects to experimentalconditions and control groupsat random.

    Randomization is like lifeinsurance. It is a precaution

    against disturbances that mayor may not occur and that

    may or may not be serious ifthey do occur (Cochran and

    Cox, 1957, p. 8).

    RandomizationWhat randomization succeeds in

    accomplishing, at least in theory, isthe conversion of all irrelevant

    sources of possible systematic

    variability into unsystematic

    variability, that is, into random error.

    The only thing that persons in group A

    should have in commonthat is, the

    only source of systematic variability

    is exposure to the same [stimulus]

    (Brown and Melamed, 1990, p. 3).

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    Control by Randomization

    Matching controls forthe effects of variationdue to specificobservablecharacteristics.

    Randomization controlsfor the effects all(observable or non-observable, known orunknown) characteristics.

    Randomization makesgroups equivalent (onaverage) on all variables(known and unknown,observable or not)

    Randomization also givesus a way to assess

    whether differences aftertreatment are larger than

    would be expected dueto chance.

    23

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    Control by Randomization

    Random assignment is notassignment with no particularrule. It is a purposeful process.

    Assignment is made at random. This does

    not mean that the experimenter writesdown the names of the varieties in any

    order that occurs to him, but that he

    carries out a physical experimental process

    of randomization, using means which shallensure that each variety will have an equal

    chance of being tested on any particular

    plot of ground(Fisher, 1935, p. 51)

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    Control by Statistical Adjustment

    Control by statistical adjustmentis a form of pseudo-matching.

    It uses statistical relations to

    simulate matching. Statistical control is important

    for increasing precision but

    should not be relied upon tocontrol biases that may existprior to assignment.

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    Using Principles of Experimental Design

    You have to have a great deal of knowledge andinformation to effectively use matching and statisticalcontrol.

    You do not have to be smart to use randomization

    effectively.