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CREATINE. Shawn Alonto • Curtis Britnell • Vince Lucente • Scott Ruston. WHAT IS IT?. A nitrogenous organic acid Found in animal products such red meat and fish Supplements First fuel source for ATP during exercise Used in the first 15 seconds of ATP production. - PowerPoint PPT Presentation
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CREATINE
Shawn Alonto • Curtis Britnell • Vince Lucente • Scott Ruston
WHAT IS IT?• A nitrogenous organic acid
• Found in animal products such red meat and fish
• Supplements
• First fuel source for ATP during exercise
• Used in the first 15 seconds of ATP production
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
PHYSIOLOGY
How Does it work?
PHYSIOLOGYHow the body synthesizes
Creatine1. Arginine, glycine form guanidoacetic acid in
kidneys2. Methylated in the liver, forming creatine 3. Transported through blood to muscles4. Concentrated in muscles as creatine phosphate
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
PHYSIOLOGYATP-CP
• ATP loses phosphate molecule
• ADP is formed
• ADP accepts donated phosphate molecule from CP
• ATP is once again formed for energy use
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
PHYSIOLOGYHuman Body & Creatine
• Adult body pool approximately 120-140g • 95% stored in muscles
• Can also be found in the liver, kidneys, sperm, eyes, and nerves
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
PHYSIOLOGYTheory behind Creatine
• Increased CP = faster ATP production
• Decreased recovery time
• High ATP levels = increased force of muscle contractions
• Increased strength and muscle size
• CP buffers intracellular hydrogen ions-lactate production-muscle fatigue during exercise
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
TARGET MARKET• Athletes (high intensity, short bouts)
• Weightlifters• Bodybuilders
http://chua2.fiu.edu/faculty/kalmand/HUN6248/ppp/MSSE%20Efx%20of%20creatine%20on%20body%20comp%20strength%20and%20sprint%20perform%20CLASSIC%20Kreider%20-Almada%201998.pdf
POTENTIAL EFFICACYEffects of creatine
supplementation on performance and training adaptations• ~300 studies evaluating ergogenic value of creatine
supplementation’ ~70% report statistically significant results. • Short term creatine supplementation: increased total creatine
content by 10-30% and phosphocreatine stores by 10-40%. • Creatine supplementation during training:↑ strength ↑ fat free mass ↑ performance high intensity exercise • No studies report an ergolytic effect.
Kreider, R. B. (2003). Effects of creatine supplementation on performance and training adaptations. Molecular and Cellular Biochemistry, 244, 89-94. Retrieved April 7, 2012
POTENTIAL EFFICACYPerformance and muscle fiber adaptations to creatine
supplementation and heavy resistance training Methods
• 19 healthy resistance-trained men with no prior creatine usage
• 12 week study: combined effects of creatine supplementation and resistance exercise
• Double-blind trial: creatine group & placebo group
• 25g creatine monohydrate / day: 5 dosages every 2-3 hours
Volek, J. S., Duncan, N. D., Mazzetti, S. A., Staron, R. S., Putukian, M., Gomez, A. L., & Pearson, D. R. (1999). Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Official Journal of the American College of Sports Medicine, 31(8), 1147-1156. Retrieved April 7, 2012
POTENTIAL EFFICACYResults
Volek, J. S., Duncan, N. D., Mazzetti, S. A., Staron, R. S., Putukian, M., Gomez, A. L., & Pearson, D. R. (1999). Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Official Journal of the American College of Sports Medicine, 31(8), 1147-1156. Retrieved April 7, 2012
POTENTIAL EFFICACYResults
Volek, J. S., Duncan, N. D., Mazzetti, S. A., Staron, R. S., Putukian, M., Gomez, A. L., & Pearson, D. R. (1999). Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Official Journal of the American College of Sports Medicine, 31(8), 1147-1156. Retrieved April 7, 2012
SUGGESTED DOSAGE
• Loading phase ~≥20g/day
• Maintenance phase ~≤5g/day
http://chua2.fiu.edu/faculty/kalmand/HUN6248/ppp/MSSE%20Efx%20of%20creatine%20on%20body%20comp%20strength%20and%20sprint%20perform%20CLASSIC%20Kreider%20-Almada%201998.pdf
POTENTIAL SIDE EFFECTS
•Results show that no reports of gastrointestinal distress and/or medical problems/symptoms.
•No evidence found of muscular cramping during resistance/agility training sessions or during performance trials.
http://chua2.fiu.edu/faculty/kalmand/HUN6248/ppp/MSSE%20Efx%20of%20creatine%20on%20body%20comp%20strength%20and%20sprint%20perform%20CLASSIC%20Kreider%20-Almada%201998.pdf
SAMPLE PRODUCTS4Ever Fit Creatine
Monohydrate500 g - $ 19.991000 g- $ 29.99
Fusion PURPLE•K 100 Cap- $39.99
Allmax Nutrition Creatine Monohydrate
100 g- $9.99400 g- $19.991000 g- $34.99
Supplements Canada. (2012). 2011 Supplement Awards. Retrieved April 6, 2012, from Supplements Canada: http://www.supplementscanada.com/ratings.htm
CONCLUSION•Creatine is a nitrogenous organic acid commonly associated
with high intensity activity and anaerobic fuel use.
•The majority of studies focusing on ergogenic value of creatine supplementation yield statistically significant results.
•With a suggested dosage of 20g/day and proper supplementation protocol, research has shown that no side effects other than weight gain have originated from creatine supplementation.
Kemper, K. (1999, November 4). Creatine. In The Longwood Herbal Task Force. Retrieved April 8, 2012, from http://www.longwoodherbal.org/creatine/creatine.pdf Brink, W. (n.d.). Creatine's usage in Sports, Health, and Anti Aging. In The Creatine Report. Retrieved April 8, 2012, from http://www.fitnessatlantic.com/pdf/creatinereport_branded.pdf
Kreider, R. B. (2003). Effects of creatine supplementation on performance and training adaptations. Molecular and Cellular Biochemistry, 244, 89-94. Retrieved April 7, 2012
Volek, J. S., Duncan, N. D., Mazzetti, S. A., Staron, R. S., Putukian, M., Gomez, A. L., & Pearson, D. R. (1999). Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Official Journal of the American College of Sports Medicine, 31(8), 1147-1156. Retrieved April 7, 2012