Cp - Pregnancy Disorder & Preterm

8/19/2019 Cp - Pregnancy Disorder & Preterm

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Risk Of Cerebral Palsy InRelation To Pregnancy

Disorders & Preterm Birth:

A National Cohort t!dy

CITRA CESILIADIVISI NEUROLOGI PEDIATRI

ILMU KESEHATAN ANAK UNPAD


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Aim

assess the risk of deveo!i"# CPi" reatio" to !re#"a"$%

disorders & !reter' (irth


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"ethod

Live (irths i" Nor)a%

*+,- . /00*

Risks of CP after !reter' deiver%& !re#"a"$% disorders

I" di1ere"t #estatio"a a#e #ro2!s


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Res!lt

*3-,4350+ $hidre" deivered at /6.46 )eeks7#estatio"

!revae"$e of CP 8 *9: !er *000 (irths9A(so2te risk of CP

• :95; at /6./- )eeks7 #estatio"• 59,; at /:.60 )eeks

• /90; at 6*.66 )eeks• 094; at 64.6, )eeks• 09*; thereafter


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Inter#retation

Ear% deiver% &!re#"a"$% 8

stro"# riskfa$tors for CPAdded risks

varied )ithi"$ate#ories of

#estatio"a a#e


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Risiko CP ? !ada keahira"!re'at2r

Keahira" !re'at2r 8 hasi !roses!atoo#is (erko"tri(2si terhada!

risiko CP

se'2a keahira" hid2! di Nor)e#ia

*+,- = /00*

risiko ter@adi"%a CP daa'kaita""%a de"#a" #a"##2a"

keha'ia" & keahira" !re'at2r


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"$TOD$

• kohort "asio"a3 data !ros!ektif

• Se'2a keahira" hid2!•

*+,-=/00*I"k2si• data 2sia keha'ia" hia"#• ahir /6 'i"##2 ata2 B 46 'i"##2 2sia

keha'ia"• L B 6 deviasi sta"dar dari (erat 2"t2k

2sia keha'ia"• 'e"i"##a daa' tah2" !erta'a

kehid2!a"• tidak terdaftar se(a#ai )ar#a Nor)e#ia

Eksk2si


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Ga"##2a"

keha'ia"a(r2!sio !ase"ta

korioa'"io"itis

!ase"ta !revia

keahira" ke'(ar

KPD

IUGR

'afor'asi ko"#e"ita

ko"isasi serviks

!erdaraha" %a"# tidak @eas

!re=eka'!sia


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Analisis tatistik

!revae"si CP = 2sia keha'ia" saat ahir& #a"##2a" keha'ia"

#a"##2a" keha'ia" & faktorsosiode'o#ra terhada! keahira"!re'at2r 6-'i"##2F & CP

h2(2"#a" #a"##2a" keha'ia" & CP


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%AI

• /90/49/*5 keahira" hid2! diNor)e#ia tah2" *+,- = /00*

• *9-,4950+ a"ak :-;F ik2t!e"eitia"

• +/96/0 53/;F a"ak ahir !re'at2r

• 69*5* a"ak CP


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DI'(I

risiko CP e(ih ti"##i!ada !ersai"a"!re'at2r &

keha'ia" de"#a"#a"##2a"

keahira" !re'at2rdise(a(ka" oeh!roses !atoo#is


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• desai" kohort "asio"a• 2k2ra" sa'!e (esar• data ko"tro (aik•

!e"#2'!2a" data!ros!ektif

Kek2ata"

• data 2sia keha'ia"

hia"# ,3*;F• d2#aa" #a"##2a"

keha'ia" & dia#"osis CPtidak dia!orka"

Keter(atasa"


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!er!a"@a"#a" keha'ia" de"#a"

ko'!ikasi da!at 'e"#2ra"#i risiko CP

CP 8 ko"sek2e"si @a"#ka !a"@a"# darikeha'ia" r2'it da" keahira" !re'at2r9

Risiko a(so2t CP seteah keahira"!re'at2r

• :35; 2"t2k sa"#at !re'at2r• 034; 2"t2k !re'at2r akhir

Seteah 2sia keha'ia" 6* 'i"##2dia#"osis ta'(aha" dari #a"##2a"keha'ia" 'e"a'(ahka" risiko CP


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TERIMA KASIH


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Critical A##raisal

Vaidit%A!akah a)a !e"eitia" dide"isika"de"#a" @eas da" !e"eitia" (er@aa"ses2ai at2ra" !e"eitia"

a

A!akah o2t$o'e di"iai se$arao(@ektif

a

A!akah se'2a !asie" %a"# 'as2kdaa' !e"eitia" di!erhit2"#ka" daa'kesi'!2a" akhir da" se'2a dia"aisisses2ai de"#a" aokasi a)a"%a

a


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A!!i$a(iit%

A!akah karakteristik !asie" kita'iri! de"#a" s2(@ek %a"# diteaah

a

A!akah !e"eitia" %a"# diak2ka"tersedia3 ter@a"#ka23 da" da!atdiak2ka" di te'!at kita

a

A!akah !e"eitia" i"i da!atditera!ka" di te'!at kita

a


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I'!orta"$e

A!akah !e"eitia" i"i !e"ti"#diak2ka" di te'!at kita a


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)alid

Im#ortant

A#llicable

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Cp - Pregnancy Disorder & Preterm