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Copyright © 2005, Elsevier, Inc. All rights reserved. Slide 11Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Chapter 6Chapter 6
The Skeletal System
2Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Learning ObjectivesLearning Objectives
• List and discuss the generalized functions of the skeletal system
• Identify the major anatomical structures found in a typical long bone
• Discuss the microscopic structure of bone and cartilage, including the identification of specific cell types and structural features
• Explain how bones are formed, how they grow, and how they are remodeled
3Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Learning Objectives (cont’d.)Learning Objectives (cont’d.)
• Identify the two major subdivisions of the skeleton and list the bones found in each area
• List and compare the major types of joints in the body and give an example of each
4Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Functions of BoneFunctions of Bone
What are five major functions of the skeletal system?
5Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Functions of BoneFunctions of Bone
• Supports and gives shape to the body• Protects internal organs• Helps make movement possible• Stores calcium• Hematopoiesis
6Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Types of BonesTypes of Bones
What are the four major types of
bones?
7Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Examples of BonesExamples of Bones
• Long Humerus (upper arm)
• Short Carpals (wrist)
• Flat Frontal (skull)
• Irregular Vertebrae (spinal cord)
8Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
• Structural components Diaphysis or shaft Medullary cavity—hollow area inside
diaphysis containing yellow marrow Epiphyses or ends of the bone—spongy
bone contains red bone marrow
Structure of Long BonesStructure of Long Bones
9Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Longitudinal Section of a
Long Bone
Structure of Long Bones (cont’d.)Structure of Long Bones (cont’d.)
10Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Microscopic Structure of Bone and CartilageMicroscopic Structure of Bone and Cartilage
There are two major types of bone.
Who knows what they are?
11Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Microscopic Structure of Bone and CartilageMicroscopic Structure of Bone and Cartilage
• Bone types Spongy
Texture results from needlelike threads of bone called trabeculae surrounded by a network of open spaces
Compact (Dense) Structural units are called osteons,
Haversian systems
12Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Microscopic Structure of Bone and Cartilage (cont’d.)Microscopic Structure of Bone and Cartilage (cont’d.)
• Cartilage Cell type called chondrocyte Has the flexibility of firm plastic Matrix is gel-like and lacks blood vessels Has no blood vessels, so nutrients must
diffuse through the matrix to reach cells
13Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Microscopic Structure of Bone
Microscopic Structure of Bone and Cartilage (cont’d.)Microscopic Structure of Bone and Cartilage (cont’d.)
14Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Bone Formation and GrowthBone Formation and Growth
• The process of “remodeling” A newborn’s skeleton has many bones that
have not completely ossified. Cartilage models replaced by calcified bone
matrix• Osteoblasts form new bone• Osteoclasts resorb bone• As long as the epiphyseal plate remains
between epiphyses and diaphysis, growth continues
• The epiphyseal line marks where two centers of ossification have fused together
Copyright © 2005, Elsevier, Inc. All rights reserved. Slide 1515Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
The SkeletonWhat are the two major divisions?
The SkeletonWhat are the two major divisions?
16Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Divisions of the SkeletonDivisions of the Skeleton
• Skeleton: Two divisions and their subdivisions Axial skeleton
Skull Spine Thorax Hyoid bone
Appendicular skeleton Upper extremities, including shoulder
girdle Lower extremities, including hip girdle
17Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
• Axial skeleton Skull Spine (Vertebral Column)
Consists of a series of separate bones called vertebrae
Sections called cervical, thoracic, lumbar, sacrum, coccyx
Curves of the spine give strength to support body
18Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
The Skull
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
19Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
The SpinalColumn
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
20Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
• Axial skeleton Thorax is formed by
12 pairs of ribs The sternum (breastbone) Thoracic vertebrae
21Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
Bones of the Thorax
22Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
• Appendicular skeleton Upper extremity formed by
Scapula (shoulder blade) Clavicle (collarbone)
o Attached by sternoclavicular joint Humerus Radius and ulna Wrist and hands—27 bones in all
23Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Bones of the Arm, Elbow Joint, and Forearm
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
24Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
• Appendicular Skeleton Lower Extremity
Two coxal (pelvic) bones Femur; longest bone in the body
o Articulates proximally with coxal bone in socket called the acetabulum
Patella (kneecap) Tibia (shinbone) Fibula (slender bone in the lower leg) Phalanges are composed of metatarsals
and tarsals
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
25Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Bones of the Thigh, Knee Joint, and Leg
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
26Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Bones of the Right
Foot
Divisions of the Skeleton (cont’d.)Divisions of the Skeleton (cont’d.)
27Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Differences Between a Man’s and a Woman’s SkeletonDifferences Between a Man’s and a Woman’s Skeleton
• Size—male skeleton generally larger• Shape of pelvis—male pelvis deep and narrow,
female pelvis broad and shallow• Size of pelvic inlet—female pelvic inlet
generally wider, normally large enough for baby’s head to pass through
• Pubic angle—angle between pubic bones of female generally wider
28Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Comparison of the Male and Female Pelvis
Differences Between a Man’s and a Woman’s SkeletonDifferences Between a Man’s and a Woman’s Skeleton
29Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Joints (Articulations)Joints (Articulations)
• Kinds of joints Synarthrosis (no movement)
Fibrous connective tissue grows between articulating bones
Example: Sutures of skull Amphiarthrosis (slight movement)
Cartilage connects articulating bones Example: Symphysis pubis
30Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Joints (Articulations) (cont’d.)Joints (Articulations) (cont’d.)
Diarthrosis (free movement)—most joints belong to this class Structures of freely movable joints—joint
capsule and ligaments hold adjoining bones together but permit movement at joint
Articular cartilage—covers joint ends of bones and absorbs jolts
Synovial membrane—lines joint capsule and secretes lubricating fluid
Joint cavity—space between joint ends of bones
31Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Joints of the Skeleton
Joints (Articulations) (cont’d.)Joints (Articulations) (cont’d.)
32Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Types of Diarthrotic Joints
Joints (Articulations) (cont’d.)Joints (Articulations) (cont’d.)
33Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Deficiency– Rickets
• Loss of bone minerals occurs in infants and
young children before skeletal maturity• Lack of bone rigidity causes gross skeletal
changes (bowing of legs)
34Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Deficiency– Osteomalacia
• First described by British surgeon Sir James Paget in
1882• Mineral content is lost from adult bones that have
already matured • Involves localized hyperactivity of osteoclasts and
osteoblasts• Faulty remodeling results in deformed bones that
fracture easily• May involve one or many bones—often appears in
spine, skull, and long bones of extremities
35Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Deficiency– Osteomalacia
• Unique symptoms (e.g., deafness, headache, facial paralysis) often caused by bone
deformity of skull bones pressing on nerves• Affects about 3% of people over age 50 (1% of cases may develop into osteosarcoma)• Cause may be genetic or triggered by viral
infections
36Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Bone infection– Osteomyelitis
• General term for bacterial (usually staphylococcal
infection of bone)• Bone infections may also be caused by viruses, fungi,
and other pathogens• Infection may be spread to bone via bloodstream,
adjacent soft tissue infection, open fractures, failed
surgical aseptic technique, or infected donor tissues or prostheses
• Symptoms caused by collection of pus and decreased
blood flow
37Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Deficiency
– Osteomyelitis• Treatment may involve surgery, drainage of
pus, and IV antibiotic treatment—often over prolonged periods
• Bone infection is often chronic and may
reappear long after an assumed cure
38Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Bone fractures – Open (compound) fractures pierce the skin and
closed (simple) fractures do not– Complete fractures involve total separation of
bone fragments, and incomplete fractures involve partially separated fragments; comminuted
fractures involve many fragments– Fracture lines can be classified by their angle
relative to a bone’s axis: linear, transverse, and oblique
39Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Noninflammatory joint disorders—do not usually
involve inflammation of the synovial membrane. Symptoms tend to be local and not systemic
• Osteoarthritis or degenerative joint disease (DJD) – Most common noninflammatory disorder of movable
joints—often called “wear and tear” arthritis.– Characterized by bone spurs and degeneration of
articular cartilage– Hips, lumbar spine, and knees often involved
40Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Noninflammatory joint disorders
• Osteoarthritis or degenerative joint disease (DJD)
– Symptoms include joint pain, morning stiffness, appearance of Bouchard’s nodes (at proximal interphalangeal joints), and
Heberden’s nodes (at distal interphalangeal joints) of the fingers
– Most common cause for partial and total hip and knee replacements
41Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Noninflammatory joint disorders
• Traumatic injury– Dislocation or subluxation—articular
surfaces of bones in joint are no longer in proper contact
– Sprain—acute injury to ligaments around
joints (e.g., whiplash type injuries)
42Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Noninflammatory joint disorders
• Traumatic injury– Strain—acute injury to any part of the
“musculotendinous unit” (muscle, tendon, junction
between the two, and attachments to bone)– Most strain injuries involve muscle tears – However, some strains may involve a weaker
component of the musculotendinous unit. In children avulsion and epiphyseal fractures may occur
43Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Inflammatory joint disorders—arthritis is a
general name for several types of inflammatory joint diseases that may be caused by infection, injury, genetic factors, and autoimmunity. Inflammation of the synovial membrane occurs, often with systemic signs and symptoms.
44Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Inflammatory joint disorders
• Rheumatoid arthritis – Systemic autoimmune disease—chronic
inflammation of synovial membrane with
involvement of other tissues such as blood vessels,
eyes, heart, and lungs– Pain, anemia, severe crippling, fever, fatigue, and
ulnar deviation of fingers are common symptoms– Juvenile rheumatoid arthritis, most common in girls
and often severe, may destroy growth cartilage and
arrest growth of long bones
45Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Skeletal Disorders
• Joint disorders– Inflammatory joint disorders
• Gouty arthritis—synovial inflammation caused
by gout, a condition in which sodium urate
crystals form in joints and other tissues• Infectious arthritis—arthritis resulting from
infection by a pathogen, as in Lyme arthritis caused by the Lyme disease bacterium
Copyright © 2005, Elsevier, Inc. All rights reserved. Slide 4646Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Let’s Review!
Chapter 6
47Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 47
Question
A role of the skeletal system is to
A. Protect vital organsB. Produce blood tissueC. Enable movement of the bodyD. Provide a framework for the bodyE. All of these are correct
48Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 48
Question
The fatty material inside long bones is
A. Red bone marrowB. White bone marrowC. Yellow bone marrowD. Blood-producing tissueE. Made mostly of calcium
49Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 49
Question
The layers of bone material that build up to form cylindrical units of bone tissue are called
A. OsteonsB. LamellaC. LamellaeD. LacunaeE. Canaliculi
50Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 50
Question
Bone-making cells are called
A. OsteoblastsB. OsteocytesC. OsteoclastsD. FibroblastsE. Osteomalacia
51Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 51
Question
The acetabulum is located in the
A. SkullB. HipC. AnkleD. NeckE. Thoracic cage
52Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Slide 52
Question
If you stand up, then bend your knee so that your leg is behind you, you have just ? the knee.
A. ExtendedB. FlexedC. AbductedD. AdductedE. Circumducted
53Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Case Study Question
• Julie is a 14-year-old girl who is 5 feet 2 inches tall. She seems short compared to her tall parents. Julie’s mother is concerned, and she asks her daughter’s physician if Julie will grow any more. How can a healthcare provider tell if Julie has completed her growth?
54Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Answer
• An x-ray study performed on her wrist. If it shows a layer of epiphyseal cartilage, then additional growth will occur. However, if it shows no epiphyseal cartilage, then her growth has stopped and she has attained adult height. This is because growth ceases when all epiphyseal cartilage is transformed into bone, and all that remains is an epiphyseal line that marks the location of where two centers of ossification have fused together.
55Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Case Study Question
• Margie, who plays center on the women’s varsity basketball team, ended up at the bottom of a pile-up during a game. When she arrives at the doctor’s office, she complains that her knee is very sore. She mentions that she felt a “pop” at the time of the injury, and the knee buckles under her weight. What should be checked?
56Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Answer
• Margie’s knee must be checked for strain on the collateral ligaments. Even though the knee is the largest joint, it is very vulnerable to forces applied from the wrong angle, particularly from the lateral side. If Margie’s collateral ligaments are sprained, she will likely need therapeutic exercise, ice packs to control pain and swelling, and use of a brace to support and stabilize the knee.
•
57Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
Fun Study Aid
• http://jeopardylabs.com/play/appendicular
58Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved.
QUESTIONS??
?