Contraindicaciones de la transfusión de plaquetas

8/16/2019 Contraindicaciones de la transfusión de plaquetas

1/37

!"#$%&'(#)(*&*("#+, )+

.%&,/0,(1# )+ 23&40+$&,

5(%6(3(" 7&3(#&, 8")%960+:


2/37

!"#$%%&'( #"*+,#$%%&'( -"#$./+0

;&%$+ )+ /&33&=+)03&%? +=(&

&>3@,(*&A=(+3")(,>3&,(&A(#B3$%&*(1# =+)03&%40(=("$+%&>(&A)%"6&,<

C<

8+)0**(1# ,+3+*DE&=+6&*&%(">"F+,(,<G%"6&, H,03/&,AD&:()&,A IJKL7M<J#/+**(1# *"#6N#($&

H!O5A %0P+"3&M +40+T",?2..7US

5&,*03(D,!@#*+% )(,+=(#&)"S.I =&3(6#&

Q+%+,>3+#(,="S+=("=& 6(6$+G(30*(1# +# $%&,/0,(1#

=&,(E&


3/37

5(6,4$" !/%&,(/. #" 7+,-8,%&2,*"(&/0

59/.$/+ 3&:(,3 ; 3?@+*$+/ 2+,-8,%&2,*"(&%/ 1(-$(" *,+ #+,:/30?@+*$+/ 2+,-8,%&2,*"(&%/ *,3A2+/36$3&'(B,/:$.,*/C/ #" %,(3$-,0

=&( 3/(:+/#,> BDE 7!DFGD=1=0 ?@+*$+/ 2+,-8,%&2,*"(&%/ 2+,-8'H%/07+,-8,%&2,*"(&/ &(#$%, *,+ I"*/+&(/0B,/:$.,*/C/ #" %,(3$-,0

B,(3"+/+ ./3%/$3/3 4$"JF5EJKJE LJM1NJ0

7+,-8,%&2,*"(&/ &(-$(" &(#$%, *,+ #+,:/30

7+,-8,%&2,*"(&/ &(#$%/ *,+ O"*/+&(/30?@+*$+/ 2+,-8,%&2,*"(&/ 2+,-8'H%/0?@+*$+/ *,32"+&,+ / 2+/(36$3&'(0B,/:$.,*/C/ #" %,(3$-,0?@+*$+/ 7+,-8,%&2,*"(&%/ 1(-$(" *+&-/+&/ %,( 3/(:+/#,0L"$%"-&/ /:$#/0


4/37

I#+=(&, S+="39D*&, O(*%"(">@D*&,

• G+>1,($" )+ &6%+6&)", >3&40+$&%(", +# 3&=(*%"*(%*03&*(1#<

•

I3$+%&*("#+, )+ W&P"%&$"%("? – I#+=(& X+="39D*& (#$%&E&,*03&% =+*@#(*& *"#

/%&6=+#$&*(1# H+,40(,$"*($",M < I#+=(& X+="39D*&=(*%"(">@D*&<

–

.%"=P"*($">+#(& )+ (#$+#,()&) E&%(&P3+<

• O(/+,$&*("#+, *39#(*&, X+$+%"6N#+&,


5/37

I#+=(&, X+="39D*&, =(*%"(">@D*&,!3&,(B*&*(1#<

•

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*& F,9#)%"=+ X+="39D*"'0%N=(*" H2..Z7SUM

•

.%"=P"*($">+#(&, )+3 +=P&%&:"? ,9#)%"=+SLWW2A >%+'+*3&=>,(& F +*3&=>,(&<

•

R$%", >%"*+,",? !JGA ,+>,(,A #+">3&,(&,)(,+=(#&)&,A S.I =&3(6#&A +#/+%=+)&)+,&0$"(#=0#+,


6/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

•

;[CV< O",*X"\($: >0P3(*& +3 >%(=+% *&," +# 0#&>&*(+#$+ )+ ;] &T", *"# 0# *0&)%" )+ (#(*("P%0,*" )+ *(#*" )9&, )+ +E"30*(1# *"# >+$+40(&,A+=(&A >&3()+: ,+60()" )+ >&%@3(,(,A *"=& F

=0+%$+<

• L,$0)(" =(*%",*1>(*" =",$%1 "*30,(1# )+&%$+%("3&, $+%=(#&3+, F *&>(3&%+, >"% $%"=P",X(&3(#",<

• 7",>+*X" +# >")+%"," E+#+#" *"# >%">(+)&)+,&630D#$+, F X+="39D*&,


7/37


8/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",

•

;[Q]< ^&+X%A _3+=>+%+% F 7*X(/%(# 0, >"%,+>&%&)" 3", $N%=(#", `>Y%>0%&aA $%"=P1D*&F `$%"=P"*($">+#(*&a<

• ;[Vb< 7(#6+%< J#$%")0*+ +3 &*%1#(=" `2


9/37

S&33&:6", )+ W&P"%&$"%("<

59"(%&/ #" O"-/C"359"(%&/ #" O"-,.&3&3

&(2+/9/3%$./+

59"(%&/J$-"(2,

#" -&%+,/(:&,*/C/7+,-8'H%/0

S+="63"P(#& P&d&<

8+D*03"*($", &0=+#$&)",<

W+0*"*($",(, *"# )+,E(&*(1#(:40(+%)&<

L,40(,$"*($", F>"3(*%"=&,(&<

I0=+#$" )+G+,X()%"6+#&,& 3@*D*&<

S+="63"P(#0%(&<

S+=",()+%(#0%(&<

S&>$"63"P(#& P&d&<

I0=+#$" )+ P(3(%%0P(#&

(#)(%+*$&<

.%"=P"*($">+#(& HefgAggg

>"% ==QM<

.< 2%"$%"=P(#& F .(+=>">&%*(&3 )+ .%"=P">3&,D#&#"%=&3<

2Gh F G(=+%" G #"%=&3<

h&*$"%+, JA 5 F 5JJJ?!#"%=&3+, " &0=+#$&)",<


10/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

• ;[]]< I="%",( F U3$=# )+,*%(P+# 3", ,(6#",*39#(*",?

– h(+P%+

–

I3$+%&*("#+, %+#&3+,<

– I3$+%&*("#+, #+0%"316(*&,< Vgi

– I#+=(& X+="39D*& =(*%"(">@D*& bfi

–

.%"=P"*($">+#(&<


11/37

!0&)%" !39#(*" )+ 2..

7+,-8,%&2,*"(&/?"2"4$&/3P "4$&-,3&3P 3/(:+/#, :&(:&9/.P "*&32/Q&3PO"-/2$+&/P -"2+,++/:&/P 3/(:+/#, :/32+,&(2"3H(/.PO"-,++/:&/ +"H("/. ; O"-,*H3&30

G&T" #+0%"316(*" Zbg'jgiM !"#/0,(1#A *+/&3+&A >&%+,(&A &/&,(&A )(,&%$%(&A >%"P3+=&,E(,0&3+,A +#*+/&3">&c&A *"=& H;giM

="$+#,(1#

7+/%2, :/32+,&(2"3H(/. N,.,+ /8#,-&(/.


12/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

• ;[bb< ^F%#+, F _X0%& )+=",$%&%"# 3&0D3()&) )+ 3& (#/0,(1# )+ >3&,=& /%+,*"*"#6+3&)"<

•

;[jg< W& (#/0,(1# )+ >3&,=& F 3& %+&3(:&*(1# )++"%/-8&, *./3-TH%, ,+ &,"*( *"# *"#$%"3)+ 3&, /"%=&, ()(">@D*&, )+ 2..<

•

;[[;< 8"*l F ^+33< 70>+%("%()&) )+ 3",+"%/-8&,3 *./3-TH%,3 ,"P%+ 3& (#/0,(1# )+>3&,=& /%+,*" *"#6+3&)" +# +3 $%&$&=(+#$"


13/37

2.. &)40(%()"< 8"*l +$ &3 ;[[;

8+*&=P(" >3&,=@D*" J#/0,(1# )+ >3&,=&7+k" HSZOM ;[ZQC ;]ZQfI"-,:.,8&(/ U-:V#LW XYVAZ0[ [ YVA Z0[

23&40+$&, C;mZ';j


14/37

8+*&=P(" >3&,=@D*" J#/0,(1# )+ >3&,=&

8+,>0+,$& HiM

nk($" CVHVbiM ;Q HCfiM

h%&*&," CbHfQiM Qj HbfiM

70>+%E(E+#*(&5(E", V[ H[]iM VQ HjViM

O0+%$", C HViM jH;]iM

2.. &)40(%()"< 8"*l +$ &3 ;[[;


15/37


16/37

• ;[jC< O"&l+< 2%+,+#*(& )+ =03c=+%", )+6% >+," ="3+*03&% )+ /&*$"% E"# o(33+P%)+# >3&,=& )+ >&*(+#$+, *"# 2.. %+*0%%+#$+<

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

b?D! cdef


17/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

• ;[[j< .,&( F h0%3 )+$+*$ &0$"'D*0+%>",J6p *"# &*DE()&) !RK.8I =+$&3">%"$+(#&,& +# >3&,=& )+ >&*(+#$+, *"# 2.. ()(">@D*&<


18/37

I#D*0+%>", D'IGIO.7;Q +# =(*%"(">&c&,$%"=P1D*&, F "$%&, +#/+%=+)&)+, &0$"(#=0#+,<

?/%&"(2"3 %,( -&%+,/(:&,*/C/3 2+,-8'H%/3 /:$#/3 /#4$&+/3

G(&6#1,D*" 2&*(+#$+,I*DE()&)

IGIO.7;Q HiMJ#X(P()"% J6 p J6 O

IGIO.7;Q e;gi Q] Q q ;g i QgZQ] HjQiM Qf H[biM VH;;iM

IGIO.7;Q r;gi ;f ;;';ggi CZf HVgiM Q HCgiM QHCgiM

?/%&"(2"3 %,( 2+,-8,%&2,*"(&/ *,+ ,2+/3 %/$3/3 #" -&%+,/(:&,*/C/3 2+,-8'H%/3 $,2+/3 /$2,&(-$("30

G(&6#1,D*" 2&*(+#$+,I*DE()&)

IGIO.7;Q HiMJ#X(P()"% J6 p J6 O

.%"=P"*($">+#(& fg Cg q ;gg i gZg VHjiM VHjiM

WL7 Vg CC q ;bC i gZf fH;QiM bH;jiM

7< D/",/"3(>9)(*" ff QC q ;;V i gZ;g QHfiM ;gH;jiM

S+="B3(& I *"# (#X(P()"% ;f ;g q [; i gZg g fHQQiM


19/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

• ;[[[< h0%3< I0,+#*(& )+ =+$&3>%"$+(#&,&40+ *3(E& +3 /&*$"% E"# o(33+P%) +#>&*(+#$+, *"# 2.. *"#6N#($"<


20/37

2Y%>0%& $%"=P"*($">+#(*& $%"=P1D*&I#$+*+)+#$+, S(,$1%(*",<

• Cgg;< h0d(l&\&&A sX+#6A W+EF >0%(B* F%+&3(: 3& ,+*0+#*(& )+ 3& =+$&3>%"$+(#&,&()+#DB*&)& *"=" IGIO.7<

O+$&3>%"$+(#&,& HIGIO.7;Q t IG(,(#$+6%(#'3(l+ I#) O+$&33">%"$+&,+ \($X+(6X$ .X%"=P"7>"#)(#'J'3(l+ )"=&(#,M – G"=(#(" &=(#"$+%=(#&3 – G"=(#(" )+,(#$+6%(#&

–

G"=(#(" .%"=P",>"#)(#&';'3(l+ – G"=(#(" %(*" +# *(,$+9#& – 7(+$+ )"=(#(", &)(*("#&3+,

$X%"=P",>"#)(#';'3(l+ – 2"%*(1# *&%P"k($+%=(#&3 *"# )", )"=(#(",

!U^<


21/37

IGIO.7 ;Q

• ?+,2"*(1# )+ >&*(+#$+,*"# 2.. )0%$+ +3 >+%(>&%$"<

?77 %,(:g(&2/ " &,*TH%/ > k ah


22/37

I*DE()&) )+ IGIO.7 ;Q


23/37


24/37

IGIO.7 ;Q +# 2.. ()(">@D*"


25/37


26/37

L,40(,$"*($",

I#+=(& =(*%"(">@D*&• !Nl /(,+-/.• FBM (,+-/.V#&3-&($,


27/37

L3 )(&6#1,D*" )+ 2.. )+P+ %+&3(:&%,+ >"%3& >%+,+#*(& )+ +=(& X+="39D*&

=(*%"(">@D*& F $%"=P"*($">+#(& +#&0,+#*(& )+ "$%& *&0,& ()+#DB*&P3+<

!"&603">&c& )+ *"#,0="<5&,*03(D, <I#+=(& X+="39D*& &0$"(#=0#+ q ,9#)%"=+ )+ LE,<

79#)%"=+ D/",/"3(>9)(*" *&$&,$%1B*"<S(>+%$+#,(1# =&3(6#&<!@#*+% )(,+=(#&)"<SLWW2 q 6+,$&*(1#<


28/37

.(>", )+ 2..

• J)(">@D*&< –

ff'bfi +>(,")(" Y#(*"< – Cf'Vfi %+*&9)&, =Y3D>3+,< – K(E+3 )+ IGIO.7 ;Q %+)0*()" ,"3" )0%$+ +3 +>(,")(" &60)"<

•

!"#6N#($&< 79#)%"=+ )+ U>,X&\'7*X03=< 8+*&9)& *&)&Q'V ,+=&,< K(E+3 )+ IGIO.7 ;Q e f'fgi

• 7+*0#)&%(&< – J#/+**("#+,< G(&%%+& X+="%%@6(*& HL< *"3( g;fb?SbM 7X(6+33&A SJ5<

–

h@%=&*",? =($"=(*(#&A *(*3",>"%(#&A 6+=*($&P(#&< – K+">3&,(&, H+,$1=&6"A =&=&M – L#/+%=+)&)+, )+ $+d()" *"#+*DE"< – !"# /%+*0+#*(& #(E+3+, )+ IGIO.7 ;Q +# 3(=($+, #"%=&3+,A *"#

=&3& %+,>0+,$& & $%&$&=(+#$" *"# >3&,=& /%+,*" *"#6+3&)"<


29/37

2..

B/2":,+0+,$& & 8+*&=P(">3&,=@D*" r jgi<uD3 (#=0#",0>%+,"%+,<

2.. ,+*0#)&%(& !@#*+%A (#/+**("#+,A/@%=&*",<

G+,*"#"*()"<

K" )NB*($ )+IGIO.7 ;Q<

L,*&,& 0D3()&) )+%+*&=P(" >3&,=@D*"<

7SU ' G(&%%+&h&33& %+#&3 &60)&"3(6Y%(*&< 2%+*+)()" )+)(&%%+& X+="%%@6(*&<

W+,(1# +#)"$+3(&3>"% $"k(#& )+ L<*"3(< IGIO.7 ;Q

#"%=&3<

K" 0D3()&) )+ %+*&=P(">3&,=@D*"<

7SU &c>(*"h&33& %+#&3 &60)&"3(6Y%(*&< 7(# )(&%%+&X+="%%@6(*&<

G+/+*$" )+%+603&*(1# )+!"=>3+=+#$"

K" 0D3()&) )+ %+*&=P(">3&,=@D*"<


30/37

2..G(&6#1,D*" )(/+%+#*(&3<

N&/:('3H%, JIFJ 2+,-8,%&2,*"(&/ I7J 50 +"(/. J6"%%&'( =EB

?+"A"%./-*3&/ Y Y YYY Y Y

I5LL? YY YYY YVA Y YVA?77 YYY YYY A YY Y

B1N Y YY A YVA YVA


31/37

2.. +# 6+,$&*(1#<

•

2+%B3 )+ *"&603&*(1# #"%=&3<

• I3$+%&*("#+, 6%&E+, )+ +,$&)" =+#$&3<

•

h&33& %+#&3 &60)& "3(6Y%(*&<• L=>+"%& $%&, >&%$"<

• !"#E03,("#+, #" &,"*(&)&, & S.I " +# >",'

>&%$"<• J#*%+=+#$" )+ GSW *"# #"%=&3(:&*(1# )+ >+%B3

X+>@D*" +# >",'>&%$"<


32/37

2...%,/0,(1# )+ 23&40+$&,<

•

=$ /#-&(&32+/%&'( "32/ BDE7!J1EN1BJNJ0

–

K" *"#$%(P0F+ & %+,"3E+% 3& $%"=P"*($">+#(&<

– 20+)+ &0=+#$&% 3& 6%&E+)&) )+ 3&,=(/+,$&*("#+, *39#(*&,<

–

KUK!I )+ &)=(#(,$%&%,+ $+, )+ (#(*(&% %+*&=P("

>3&,=@D*"<


33/37

2.. ()(">@D*" ' .%&$&=(+#$"<

•

2%(=+%& 39#+&< – 23&,=&/+%+,(, $+%&>N0D*&< jgi )+ +B*&*(&< !&$+6"%9& ;

– G(&%("< !%($+%(", )+ %+,>0+,$&? >3&40+$&, r;ggAgggZ==Q

• 7+60#)& 39#+&< –

h%&*&," & >3&,=&/+%+,(,?• I)(*("#&% +,$+%"()+,<

• I0=+#$&% /%+*0+#*(& )+ >3&,=&/+%+,(, H)", E+*+, &3 )9&M

• 8($0k(=&PA E(#*%(,D#&A *(*3"/",/&=()&<

–

8+*&9)&,< W0+6" )+ ,0,>+#)+% &/N%+,(,<• E, O/; 6,+-/ #" *+"9"+0

• 2%+*"*+,? 5(#*%(,D#&A +,>3+#+*$"=9&A %($0k(=&P

• .&%)9&,? >3&,=&/+%+,(,<


34/37

!"%D*"()+, +# 2..7,2/. #" */%&"(2"3

Z_X

532"+,"3 Ua^W !? Y 532"+,"3 Ua^W

532"+,"3 U\_W !"3&32"(%&/ ]^ !? Y 532"+,"3 U`XW

!"-&3&'( %.


35/37

8($0k(=&P +# 2..<

•

ZZ */%&"(2"3> – ?77 +"6+/%2/+&, UmW – ?77 +"%$++"(2" UaW – J(H%$"+*, /(H JNJF7= Z\ "( Z__h –

J%H9/# JNJF7= Z\ k Z_h

• N,3&3> \`a -:V-] 5M 3"-/(/. *,+ ^ 3"-/(/3

• !"-&3&'( %.


36/37

2.. +# +3 S",>($&3 59*$"% W&:&%$+<• f >&*(+#$+,<•

7+k" HOZhM t CZQ<• L)&) =+)(& t QQ0P3(*&)"<

• .(+=>" )+ +E"30*(1#< LOL8pLK!JI OLGJ!I<

– !"%$& +E"30*(1# HQ >&*(+#$+,M b&*(+#$+,<


37/37

o!JB1J=E(%6(3("

Documents

Contraindicaciones de la transfusión de plaquetas