Contents – Eur. J. Immunol. 1/2007

1 Editorial

8 In this Issue

10 News and EFIS

Commentary:

14 New vistas on macrophage differentiation and activationAlberto Mantovani, Antonio Sica and Massimo LocatiSee accompanying article

Commentary:

17 To switch or not to switch – the opposing roles of TACI in terminalB cell differentiation

Ulrich Salzer and Stephanie Jennings and Bodo GrimbacherSee accompanying article

Commentary:

21 FOXP3: Not just for regulatory T cells anymoreSteven F. ZieglerSee accompanying article

Frontline:

24 Vanin-1 controls granuloma formation and macrophage polarizationin Coxiella burnetii infection

Soraya Meghari, Carole Berruyer, Hubert Lepidi, Franck Galland,Philippe Naquet and Jean-Louis MegeSee accompanying commentary

Frontline:

33 Macrophage fusion induced by IL-4 alternative activation is amultistage process involving multiple target molecules

Laura Helming and Siamon GordonSee accompanying commentary

Frontline:

43 Faithful activation of an extra-bright red fluorescent protein in“knock-in” Cre-reporter mice ideally suited for lineage tracingstudies

Herv� Luche, Odile Weber, Tata Nageswara Rao, Carmen Blum andHans J�rg Fehling

A swiss roll of the smallintestine with some prominentSILT

Forum

Highlights

Eur. J. Immunol. 2007. 37: 4–74

f 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.eji-journal.eu

54 Functional expression of chemokine receptor CCR6 on human effectormemory CD8+ T cells

Takaaki Kondo, Hiroshi Takata and Masafumi Takiguchi

66 Helper function of cytolytic lymphocytes:Switching roles in the immune response

Giuseppina Li Pira, Federico Ivaldi, Laura Bottone, Gerrit Koopman andFabrizio MancaSupporting Information available online

78 CD8+ suppressor-mediated regulation of human CD4+ T cell responsesto glutamic acid decarboxylase 65

Eddie A. James and William W. Kwok

87 Regulation of intestinal immunity: Effects of the oral adjuvantEscherichia coli heat-labile enterotoxin on migrating dendritic cells

Simon W. F. Milling, Ulf Yrlid, Chris Jenkins, Claire M. Richards,Neil A. Williams and Gordon MacPherson

100 The germinal center response is impaired in the absence ofT cell-expressed CXCR5

Carrie N. Arnold, Daniel J. Campbell, Martin Lipp and Eugene C. Butcher

110 TACI attenuates antibody production costimulated by BAFF-R and CD40Daisuke Sakurai, Yumiko Kanno, Hidenori Hase, Hidefumi Kojima,Ko Okumura and Tetsuji KobataSee accompanying commentary

Immunoperoxidase staining ofB220 in NOD mouse islets

Cellular immune response

119 Dynamics and magnitude of virus-induced polyclonal B cell activationmediated by BCR-independent presentation of viral antigen

Evan R. Jellison, Heath M. Guay, Eva Szomolanyi-Tsuda andRaymond M. Welsh

Invasion of a dendritic cell byTrypanosoma cruzi

Immunity to infection

129 Transient expression of FOXP3 in human activated nonregulatoryCD4+ T cells

Jun Wang, Andreea Ioan-Facsinay, Ellen I. H. van der Voort,Tom W. J. Huizinga and Ren� E. M. ToesSupporting Information available onlineSee accompanying commentary

139 Activation of CD4+CD25+ regulatory T cell suppressor function byanalogs of the selecting peptide

Joseph Larkin III, Cristina Cozzo Picca and Andrew J. Caton

Systemic antitumor therapy

Immunomodulation

Eur. J. Immunol. 2007. 37: 4–7 5


147 Development of CD25– regulatory T cells following hearttransplantation: Evidence for transfer of long-term survival

Nicolas Degauque, David Lair, C�cile Braudeau, Fabienne Haspot,Fabien S�bille, Alexandre Dupont, Emmanuel Merieau, Sophie Brouard andJean-Paul Soulillou

157 Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survivaland significantly increases recall responses

Carl E. Ruby, William L. Redmond, Daniel Haley andAndrew D. WeinbergSupporting Information available online

167 Terminal complement complex C5b-9-treated human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization

Yongwen Chen, Chengying Yang, Naishi Jin, Zhunyi Xie, Yuyu Tang, Lei Fei,Zhengcai Jia and Yuzhang Wu

177 IL-10 inhibits endothelium-dependent T cell costimulation byup-regulation of ILT3/4 in human vascular endothelial cells

Christian A. Gleissner, Arne Zastrow, Roland Klingenberg, Martin S. Kluger,Mathias Konstandin, Sultan Celik, Susanne Haemmerling, Vijay Shankar,Thomas Giese, Hugo A. Katus and Thomas J. Dengler

Short Communication:

193 Modulation of 2B4 (CD244) activity and regulated SAP expression inhuman NK cells

Johanna Endt, Philipp Eissmann, Sabrina C. Hoffmann, Stephan Meinke,Thomas Giese and Carsten Watzl

199 Three common alleles of KIR2DL4 (CD158d) encode constitutivelyexpressed, inducible and secreted receptors in NK cells

Jodie P. Goodridge, Louise J. Lathbury, Noriko K. Steiner,Christine N. Shulse, Philomena Pullikotil, Nabil G. Seidah,Carolyn K. Hurley, Frank T. Christiansen and Campbell S. Witt

212 Genetic analysis of the innate immune responses in wild-derivedinbred strains of mice

Kristin Stephan, Irina Smirnova, Berri Jacque and Alexander Poltorak

224 Mast cell-expressed complement receptor, not TLR2, is the maindetector of zymosan in peritonitis

Sarah C. Mullaly and Paul Kubes

VAP-1 expression in permeabi-lized CHO cells

Innate immunity

Eur. J. Immunol. 2007. 37: 4–76


Short Communication:

235 Enhanced intra-switch region recombination during immunoglobulinclass switch recombination in 53BP1–/– B cells

Bernardo Reina-San-Martin, Junjie Chen, Andr� Nussenzweig andMichel C. NussenzweigSupporting Information available online

240 Stimuli that enhance IgA class switching increase histone 3 acetyla-tion at Sa, but poorly stimulate sequential switching from IgG2b

Denise A. Kaminski and Janet StavnezerSupporting Information available online

252 The Ig-a ITAM is required for efficient differentiationbut not proliferation of pre-B cells

Bettina Storch, Sonja Meixlsperger and Hassan JumaaSupporting Information available onlineDemyelinating MOG epitopes

Molecular immunology

261 Phospholipase Cc negatively regulates Rac/Cdc42 activation inantigen-stimulated mast cells

Mirvat El-Sibai and Jonathan M. Backer

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Leukocyte signaling

cytC and Bax staining of B cells

271 FTY720 enhances the activation-induced apoptosis of donor T cellsand modulates graft-versus-host disease

Daigo Hashimoto, Shoji Asakura, Ken-ichi Matsuoka, Yukimi Sakoda, MotokoKoyama, Kazutoshi Aoyama, Mitsune Tanimoto and Takanori Teshima

282 CD4+CD25high regulatory T cells reduce T cell transendothelialmigration in cancer patients

Karin Enarsson, B. Samuel Lundin, Erik Johnsson, Thomas Brezicka andMarianne Quiding-J�rbrink

Histopathology of the knee joint

Clinical immunology

Eur. J. Immunol. 2007. 37: 4–7 7


Documents

Contents – Eur. J. Immunol. 1/2007