Contents

Part I Bones

Reliable Patient-Specific Simulations of the Femur . . . . . . . . . . . . . . . 3Zohar Yosibash and Nir Trabelsi

Patient-Specific Diagnosis and Visualizationof Bone Micro-Structures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27L. Podshivalov, A. Fischer and P. Z. Bar-Yoseph

Patient Specific Modeling of Musculoskeletal Fractures . . . . . . . . . . . 53Eran Peleg

Part II Spine

Advancements in Spine FE Mesh Development:Toward Patient-Specific Models . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75Nicole A. Kallemeyn, Kiran H. Shivanna, Nicole A. DeVries,Swathi Kode, Anup A. Gandhi, Douglas C. Fredericks,Joseph D. Smucker and Nicole M. Grosland

Patient-Specific Modeling of Scoliosis . . . . . . . . . . . . . . . . . . . . . . . . . 103J. Paige Little and Clayton J. Adam

Subject-Specific Models of the Spine for the Analysisof Vertebroplasty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133Alison C. Jones, Vithanage N. Wijayathunga, Sarrawat Rehmanand Ruth K. Wilcox

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Part III Heart and Circulation

Morphological and Functional Modeling of theHeart Valves and Chambers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157Razvan Ioan Ionasec, Dime Vitanovski and Dorin Comaniciu

Patient-Specific Analysis of Blood Flow and Mass Transportin Small and Large Arteries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189X. Y. Xu, N. Sun, D. Liu and N. B. Wood

Patient-Specific Modeling of Leg Compression in the Treatmentof Venous Deficiency . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217Stéphane Avril, Pierre Badel, Laura Dubuis, Pierre-Yves Rohan,Johan Debayle, Serge Couzan and Jean-François Pouget

Part IV Airways

Scan-Based Flow Modelling in Human Upper Airways . . . . . . . . . . . . 241Perumal Nithiarasu, Igor Sazonov and Si Yong Yeo

A Decission Support System for Endoprosthetic Patient-SpecificSurgery of the Human Trachea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281Olfa Trabelsi, Angel Ginel, Jose L. López-Villalobos,Miguel A González-Ballester, Amaya Pérez-del Palomarand Manuel Doblaré

Part V Brain

Image-Based Computational Fluid Dynamics for Patient-SpecificTherapy Design and Personalized Medicine . . . . . . . . . . . . . . . . . . . . 337Andreas A. Linninger

Patient-Specific Modeling and Simulation of DeepBrain Stimulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Karin Wårdell, Elin Diczfalusy and Mattias Åström

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Part VI Patients-Specific Modeling in Diagnostics, SurgicalPlanning and Rehabilitation

Patient-Specific Modeling of Breast Biomechanics with Applicationsto Breast Cancer Detection and Treatment. . . . . . . . . . . . . . . . . . . . . 379Thiranja P. Babarenda Gamage, Vijayaraghavan Rajagopal,Poul M. F. Nielsen and Martyn P. Nash

Soft-Tissue Simulation for Cranio-Maxillofacial Surgery:Clinical Needs and Technical Aspects. . . . . . . . . . . . . . . . . . . . . . . . . 413Hyungmin Kim, Philipp Jürgens and Mauricio Reyes

Patient-Specific Modeling of Subjects with a LowerLimb Amputation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441Sigal Portnoy and Amit Gefen

Patient-Specific Modeling of the Cornea . . . . . . . . . . . . . . . . . . . . . . . 461Roy Asher, Amit Gefen and David Varssano

Part VII Systems Biology Approaches in Patients-Specific Modeling

Computational Modeling of Gene Translation and its PotentialApplications in Individualized Medicine . . . . . . . . . . . . . . . . . . . . . . . 487Tamir Tuller and Hadas Zur

Neural Network Modeling Approaches for Patient SpecificGlycemic Forecasting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505Scott M. Pappada and Brent D. Cameron

Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531

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