CON8277Personalizing Treatment with Oracle Health Sciences Translational Research Center Cloud Service

Speaker Bio

Prof. Dr. Peter vd SpekHead of BioInformatics dept.Erasmus MC Rotterdam

Ing. René KuipersPrincipal Consultant OracleVX Company Healthcare Analytics

Percentage of the patient population for which a drug is ineffective on average

What must change to allow personal healthcare ?

And you need a platform: Oracle Translational Research Center

Oracle Translational Research Center

Oracle Translational Research Center

HDWF CDM

ODB

• Source data loaders• Transformation (OHADI)• Datamart loaders (SCE ETL)• Result loaders (OMICS data)

• CGI• RNASeq• RNA Expression• Copy Number Variation• ……

Use case: Malformations of the Skull (Craniosynostosis)

Cohort definition

Cohort analysis (Oracle Business Intelligence Enterprise Edition)

Single patient viewer

Single patient viewer

Oracle Translational Research Center: Open platform

Oracle Translational Research Center: Open platformCustom Extensions

– TRC cross-domain– Not just Craniosynostosis, or Cancer, or ……

– Centralized repository for clinical and OMICS data– Consolidation of data, information and knowledge

– Lowers IT spend– Improves quality of care

– TRC to be made available as Cloud-platform for (smaller) research institutions and medical centers.– Lowers IT spend even more– More data, better analytics, better care

Erasmus MC, VX Company Healthcare Analytics and Oracle TRCFuture goals

Q&A