ComET Peer Input Meeting ComET Peer Input Meeting Path Forward Path Forward

Nov. 8th, 2004Nov. 8th, 2004

BBette Meek, Health Canadaette Meek, Health Canadawww.hc-sc.gc.ca/exsd-dsewww.hc-sc.gc.ca/exsd-dse

2ComET Peer Input meeting, Cincinnati, Nov. 8th, 2004

Keep in Mind

• Development of this “tool” (ComET) is a work in progress– Default values provided principally as examples,

for illustration, currently– Not encompassing at this stage

• Continuing suggestions are welcome, but this is NOT peer review– Deadline will determine form of peer review pre

2006• It is the “tool” (ComET) which is the focus of this

meeting, not the substances– Substances for illustrative purposes, only

• “Tool” currently a spreadsheet but form will change

3ComET Peer Input meeting, Cincinnati, Nov. 8th, 2004

Where to From Here?

• Expansion of numbers of scenarios to be encompassing for substances in the program

• Application of tool to remainder of substances on the high and mid groups of the maximal list– Where data/information will help

• Development of a more efficient platform (moving from Access/Excel)– Data entry aids, menu selections

• Review/revision of specific scenarios – Consistency

4ComET Peer Input meeting, Cincinnati, Nov. 8th, 2004

Additionally Focussing Effort – the Maximal List

• Focus on 1573 substances in “high” and “mid” groups• Subset of 314 substances in the “high” likelihood

group, identified on basis of hazard for which exposure is low– Risk management in place?

• Subset of 388 substances in the “mid” likelihood group for which determinations of persistence or bioaccumulation will contribute

• Data limited for certain types of substances– UVCBs, polymers

• To extent possible, will identify the more limited numbers of substances for which additional information on toxicity will be helpful

5ComET Peer Input meeting, Cincinnati, Nov. 8th, 2004

Current Path/Timeline

2004-01-01 2005-01-01 2006-01-012003-09-14 2006-09-14

Fall 2005Release of Integrated

Framework for theHealth-Related Components

of DSL CategorizationNovember 2003 - April 2004Written Review Period for

Proposed InitialGPE List

March 8, 2004Information Session

November 22, 2004Information Session

November 8, 2004Peer Input MeetingComplex Exposure

Tool

October 19, 2004Release of Health Canada

Draft “Maximal” List

Fall 2004/Winter 2005Release of Proposed Integrated

Framework for theHealth-Related Components

of DSL Categorization

6ComET Peer Input meeting, Cincinnati, Nov. 8th, 2004

More Information?

• Health Canada Existing Substances Division Website – http://www.hc-sc.gc.ca/exsd-dse

• Health Canada Existing Substances Mailing List – http://www.hc-sc.gc.ca/hecs-sesc/exsd/listserv.htm

• CEPA Registry – (http:// www.ec.gc.ca/CEPARegistry)