Combined 2004 Annual Report & Financial Statement

© 2 0 0 5 A L S T H E R A P Y D E V E L O P M E N T F O U N D A T I O N | 10

111

a l s t h e r a p y

d e v e l o p m e n t f o u n d a t i o n

[ a n n u a l r e p o r t 2 0 0 4 ]

215 First St., Cambridge, MA 02142

P H O N E : 617.441.7200 F A X : 617.441.7299

E M A I L : [email protected] W E B : www.als.net

Brothers Ben, Stephen, and James Heywood, with Stephen’s son Alex

Inspired by the families who are fearless in battling

against one of the world’s most challenging

diseases, ALS TDF was founded as a nonprofit bio-

technology company that aggressively researches

treatments for patients living with ALS today.

Our approach combines the power of a nonprofit

mission with the best practices of a leading-edge

biotechnology company using rigorous, open-minded

research and proven drug development techniques.

patients today

2004 Completed the evaluation of over 700

compounds; including in vivo animal

testing of over 100. More animal

studies than all other ALS labs have

published combined.

Established funding and architecture

for the Quantitative Gene Expression

Core Program.

Developed intrathecal catheter to

target drugs to mouse spine.

Friends and Family Community

reaches the $5.5 million mark in

three years.

Two ALS TDF drugs, Ritonavir and

Hydroxyurea, begin clinical trial at UCSF.

ALS TDF researchers show traditional

drug dosing methods are ineffective

when targeting the spinal cord.

Driving 4 Life established by Tom

Watson, Bruce Edwards and Jeff Julian

to fund ALS TDF research.

ALS TDF research establishes its first

clinical trial candidate, Ritonavir.

Digital pipeline created to track

all possible therapeutics and move

them efficiently from investigation

through testing.

Neurobase implemented to track over

400 data-points per animal, per study.

ALS TDF establishes world’s largest

ALS mouse screening program, with

comprehensive formulation and

dosing evaluation.

ALS TDF research leads to the first

published human stem cell transplant

in ALS.

New Yorker article about the Heywood

family’s quest for a cure.

ALS TDF and collaborators develop

human protocol for gene therapy to

treat ALS.

ALS TDF founded.

Over the last four years we have completed testing most of the proposed ALS therapies in almost ten thousand mice, more than all other ALS labs combined. We have made significant discoveries and advances including overcoming the barrier of administering drugs directly into the spinal cord. We refined our method of testing, improved quality and confirmed that the mouse model still accurately predicts the results of clinical trials. These results set a desperately needed standard for preclinical validation for the entire ALS research field.

Our efforts are now focused on important new therapeutic target areas including protein conformation, inflammation, the proteasome and cell cycle. ALS TDF is building programs to identify new therapies in each of these areas. These targets offer real hope to slow ALS but we also need new discoveries to find treatments that will stop it.

To succeed, we must expand our scope beyond drugs and therapies. The skills we developed to tackle therapeutics can and must be applied to biomarkers. Comprehensive disease profiling is ready for the information technology and rigor ALS TDF can bring to bear. Integrating biomarker, therapeutics and comprehensive disease profiling, we can unlock new ideas and make them rapidly relevant

to patients. This is the program that is required to find an effective treatment for ALS.

ALS TDF is ready for this challenge and today’s ALS patients deserve nothing less.

Thank you for making possible my faith that we can stop ALS.

james allen heywood

d’Arbeloff Founding Director

2003

2002

2001

2000

1999

T I M E L I N E

ALS TDF Today

At Left: James and Stephen Heywood

Intrathecal Mouse CatheterWhile human ALS may spread along the length of the spinal cord and motor cortex, the mouse disease is more pronounced in the lumbar spinal cord. To treat the disease in mice, drugs will need to reach the primary site of degeneration in the lumbar spinal cord. In early 2004, ALS TDF measured drug levels in the spinal cord from conventional drug delivery methods and discovered that many drugs did not reach the spinal cord effectively. In medical literature there is little data addressing spinal cord penetration in mice, an animal model used for much medical research. In order to solve this critical problem, ALS TDF researchers developed an intrathecal infusion system which is a novel technique where a catheter and pump are used to continually deliver drugs directly into the mouse spinal cord.

ALS TDF made great strides in the development of the catheter system in the second half of 2004. The original system allowed for a one-time drug injection into the

spinal cord. With the adaptation of a mini osmotic pump to the catheter, drugs are now pumped around the clock into the spinal cord. The device doses directly and continuously to the mouse spinal cord allowing researchers at ALS TDF to achieve drug levels that are much greater than pumping via the brain. Results suggest that the levels of drug reaching the spinal cord are fifty times higher than those achieved using brain delivery.

“ALS TDF’s ability to pump

drugs directly into the

spinal cord of a mouse

is an impressive and

unprecedented development

that should speed drug

discovery for ALS.”

fred vinickSenior Vice President, Drug Discovery Genzyme Corporation

Initially, pump implant surgeries required a two-hour procedure. Within a few months, ALS TDF streamlined the process to accommodate over forty animals in half a day, sufficient to implement full efficacy studies. Studies have been performed to monitor the impact of surgery on lifespan and neurological function. Results suggest that the procedure is not detrimental to the animal or the disease.

For patients this means that for the first time researchers can test drugs thoroughly and better utilize the most advanced therapies including siRNA, gene therapy, and protein therapeutics. In addition, the catheter is a hopeful advancement since many therapies tested in the past by ALS researchers likely did not achieve therapeutic levels because they simply did not reach the intended target. The creation of this innovative drug delivery system vastly increases the opportunity for success in the evaluation and eventual development of treatments for ALS.

2 | a l s t h e r a p y d e v e l o p m e n t f o u n d a t i o n | A n n u a l R e p o r t 2 0 0 4

Accelerating A Cure Inspired by Passion:

Mary Lou Krauseneck was diagnosed with

ALS in June of 2000. Since that time she

has fought the disease with uncommon

courage and faith. Shortly after diagnosis,

her family, friends and community formed

A Passion for Life, an annual event that

raises awareness of ALS and supports

ALS TDF research. In 2004, A Passion for

Life worked to help fund the development

of the Intrathecal Mouse Catheter, a

development that is promoting accurate

research and ensuring every tested

therapy reaches its intended target.

Mary Lou Krauseneck with niece Amy Whipple.


© 2 0 0 4 A L S T H E R A P Y D E V E L O P M E N T F O U N D A T I O N / P A G E 3

Our Team: Research and Development Staff

Our Team: Senior Research and Development Staff

Quantitative Gene Expression Core Program

ALS TDF is pursuing an aggressive program dedicated to finding biomarkers of disease progression critical for studying drug effect in the ALS mouse model. In 2004, ALS TDF purchased a real-time quantitative polymerase chain reaction (RT-qPCR) machine and hired the staff to design and manage our new Quantitative Gene Expression Core Program.

The program aims to measure changes in gene expression (the quantity of RNA produced for a given gene) as a result of the disease process. Thus far we have detected genes whose expression is altered by 20-fold or more. This highly quantifiable system will allow us to validate alterations that were previously seen in

microarray data generated for this purpose.

With this new, leading-edge technology, we can accurately and precisely measure gene expression changes. Tracking can be done in all tissue types from blood to spinal cord to brain. This program is a significant and vital boost to our ability to rapidly generate biomarkers and validate drug effect.

Through a concerted fundraising effort mounted by ALS TDF supporters, The Research Center at ALS TDF has been equipped with the necessary materials and resources needed to launch this much needed research. Ultimately our RT-qPCR approach will lead to identification of targets for disease intervention and establishment of biomarkers that can be used for the prognosis and tracking of ALS. Once an effective biomarker for ALS is discovered patients will be one step closer to a cure.


Funding the Research:

Several groups came together to raise the

funds necessary to launch our Quantitative

Gene Expression Core Program. When ALS

TDF’s need was outlined, each of these

donors generated contributions to support

our planned initiative. Many thanks to

the Ken Melanson’s Quest for a Cure, Ride

for Life’s Research Fund, The William

& Elizabeth Rieth Charitable Trust, Ms.

Marilyn Adams, and an anonymous donor.

Together, we will open a new door for ALS

research in 2005.

From the left, Jerry De Zutter, Ph.D., ALS TDF’s

Director of Gene Expression Core with Joan Melanson

of Ken Melanson’s Quest for a Cure and Christopher

Pendergast, Founder and President of Ride for Life.

Our Team: The Development Office staff cultivates

relationships with individuals and

foundations supporting ALS TDF’s research

program, as well as interaction with both

state and federal government.

Families Make a Differencematt dowd and family

Soon after Matt Dowd’s diagnosis in 2002, he attended one of the ALS 101 Seminars. Matt was driven to understand the disease, the science and research and found kindred spirits in ALS TDF’s community and staff. Since then Matt has become a prolific voice in the ALS community, regularly posting to his website and participating in online forums. Matt is a close friend and constant supporter of the foundation, continuing to inspire and challenge ALS TDF staff.

“Over the last few years I’ve been a witness to the way others look at TDF; what once was a fringe radical research group has evolved into an innovative and trusted source of testing within the ALS research community,” says Matt, “I have trust in the results and opinions that TDF generates because it is based on repeatable data-driven research.”

Matt has both intellectually encouraged ALS TDF research and funded it. Since 2003, Matt and his friends, David MacTavish and Scott Govoni, have planned an annual golf tournament at Glen Ellen Country Club in Holliston, Massachusetts to fund ALS TDF research. In addition, he and fellow patient Brent Paulhus sparked the “Reverse the Curse, Cure ALS” program in 2004 that not only brought much needed funds to ALS TDF but also helped to spur on Matt’s beloved Red Sox to victory.

the adraktas family

Devastated by their brother Dean’s diagnosis of ALS, Stephanie Adraktas and her sisters became determined to help find a cure for their brother. While searching the internet for possible ALS therapies, Stephanie discovered the story of the Heywoods. She was immediately inspired, and knew that her family should join in the mission of ALS TDF. Initially, Stephanie and her husband, John Krull, began fundraising for ALS TDF by donating earnings from items they sold on eBay. A few months later, Dean and Katherine’s neighbor, Keith Lipp, wanted to make a donation on Dean’s behalf, so the family contacted ALS TDF about setting up a special fund and the Dean Adraktas Fund was born.

“By supporting ALS TDF, we are supporting the organization we believe will find a cure any day now,” said Dean’s wife, Katherine

Adraktas. “ALS TDF’s determination, aggressive research, and overall understanding of the disease gives us confidence that soon we will receive a call from Jamie Heywood telling us the good news. We are waiting for that day.”

Dean’s family appreciates that money raised for ALS TDF goes primarily toward research. Since their initial involvement, family and friends of the Adraktas’ have held a multitude of events year-round to raise funds and awareness for ALS TDF. Dean Adraktas’ family has unquestionably made a considerable impact in ALS TDF’s mission to find a cure.


Our Team: The staff of Program Services works to

help people who are actively advocating

a cure for ALS through events and

awareness programs.


< Dean Adraktas with friend Barb Broadbear

Matt Dowd & baby Matt MacTavish >

Inspiration

dr. richard k. olney

Dr. Olney first developed an interest in ALS when the daughter of his favorite teacher in junior high

school died of the disease. His interest in central nervous system disorders led him to consider ALS one of the most intellectually compelling and alarming in its manifestation. Consequently, Olney devoted much of his twenty-five years as a neurologist to the care of ALS patients and founded the ALS Patient Care and Research Center at the University of California at San Francisco.

In 2004, Dr. Olney was himself diagnosed with ALS. Since his diagnosis, he continues his efforts to battle the disease, working to raise awareness and funds to support the quest for a cure. Amid an outpouring of sympathy, his diagnosis has focused new public attention on efforts to find the cause of, and eventually a cure for this fatal disease. ALS TDF’s relationship with Olney began in 2000, when the world-renowned neurologist and ALS researcher engaged in ALS TDF’s efforts to investigate the intrathecal IGG

treatment that patients were receiving in Puerto Rico. Since then, Dr. Olney has been a trusted collaborator and advisor to ALS TDF’s research team.

“Rick is a man who never forgets that each patient is a person,” commented Sean Scott, ALS TDF’s Vice President of Research and Development, whose mother was treated by Dr. Olney. “Rick was strong for patients when they no longer had strength. He was their voice when they could no longer speak.”

Although Olney handled patients directly, he also emphasized the need for more research and contributed in a number of national multi-center trials. In an amazingly selfless act, Olney was the first to sign up for an ALS TDF-sponsored clinical trial at UCSF for two drugs that have shown promise in extending the lifespan of laboratory SOD1 mice. Dr. Olney is the very embodiment of the passionate collaborators with whom ALS TDF endeavors to partner. Dr. Olney’s tireless efforts continue to guide our research program and serve to augment our efforts to leave no stone unturned in the quest to cure ALS.


christy sloan

ALS TDF wishes to celebrate and honor the life of Sarah Christine

“Christy” Sloan for

her passionate and extraordinary contribution to the fight against ALS. Following her diagnosis, Christy, an active outdoors-woman and banking executive with First Union Bank in Charlotte, North Carolina, founded the ALS Race for Research Foundation together with her parents, Jim and Joanna Sloan.

Since 2001, the ALS Race for Research Foundation has hosted a number of golf tournaments and events to raise funds for ALS research, always guided by Christy’s motto that, “doing nothing is not an option.” The ALS Race for Research Foundation and the Sloan Family became good friends of ALS TDF and have been generous supporters of our research program with contributions exceeding $100,000 over the last four years. Despite the recent loss of Christy in September of 2004, the Sloan family remains steadfastly committed to the cause and are determined to continue helping other families affected by the ravages of ALS.


Driving 4 LifeDriving 4 Life, the ALS research fundraising program founded by former PGA TOUR© pros Jeff Julian and Tom Watson, and caddy Bruce Edwards, has raised nearly $2 million for The Research Center at ALS TDF, significantly advancing its aggressive approach to curing ALS. In 2004, both Jeff and Bruce lost long, hard-fought battles to ALS. Bruce in April, Jeff in July. Bruce passed away the day after being awarded the distinguished Ben Hogan Award. Jeff won the honor in 2003.

In late December 2004, Kim Julian joined the ALS TDF staff full-time, moving her son, Tyler, from their home in Branson, Missouri to Cambridge, Massachusetts to act as Founding Director of Driving 4 Life. Continuing to carry out the mission of her late husband Jeff, and friend Bruce, she has laid the groundwork for a host of new relationships within the golfing and ALS communities. In the fall of 2005, Curt Schilling joins Kim as Honorary Co-Chair of the 2nd Annual Driving 4 Life Invitational, being held at Trump National, Bedminster, New Jersey.

“ALS will not be cured soon unless we increase our research efforts,” explains Tom Watson. “Funding of these efforts simply must be increased to make the percentages favor a cure being found sooner rather than later. “

Dozens of tournaments and other fundraisers are planned under the Driving 4 Life umbrella every year with thousands of golfers joining the fight against ALS and continuing Bruce and Jeff’s legacy. Driving 4 Life has quickly become the premiere charity golf program in the United States thanks to the efforts of supporters, event organizers, country clubs, retailers, and the PGA TOUR© family.

Our Team: The Driving 4 Life team develops

opportunities to fund ALS research

through celebrity golf events and by

guiding local events with the aid of

campaign supporters nationwide.

Doug McGuiness first learned about

ALS TDF from an article in 2000 and

found the story of Jamie and Stephen

Heywood compelling. As a person with

ALS he appreciates the protocol that

speeds the process of searching for a cure

or a treatment that could slow disease

progression.

Doug was invited to participate in the

golf tournament sponsored by HMS Host

International in Tampa, Florida for the

first time in 2003 by Jeff Yablun, the Vice

President of Operations for HMS Host. At

every subsequent event, Doug has been

asked to speak on behalf of other ALS

patients and drive home the need for

action in the face of ALS.

“All I can say is thank you to Jeff Yablun for

hosting these events. With a disease like

ALS, time is something that we all fight,”

says Doug, “and money is needed to carry

on that fight.”

Since its inception, the HMS Host Golf

Classic has become a model for the Driving

4 Life charity golf program at ALS TDF.

Along with funding ALS research to find

treatments, the event continues to raise

significant awareness of ALS.


F I N A N C I A L R E P O R T 2 0 0 4

Expenses

Research & Development 2,802,277.00

Patient Services 231,106.00

Fundraising 461,427.00

Management & General 301,014.00

Total Expenses $ 3,795,824.00

Increase/(Decrease) in Net Assets (347,861.00)

Net Assets: Beginning of Year 1,041,873.00

Net Assets: End of Year $ 694,012.00

Assets

Cash 865,970.00

Accounts Receivable 20,000.00

Fixed Assets-Net 139,692.00

Other Assets-Net 16,908.00

Total Assets $ 1,042,570.00

Liabilities and Net Assets

Liabilities 348,558.00

Net Assets 694,012.00

Total Liabilities and Net Assets $ 1,042,570.00

Support & Revenue

Contributions 1,180,135.00

Grant Receipts 482,806.00

Fundraising Events 1,631,686.00

In-Kind Donations 156,235.00

Interest, Dividends & Gains/Losses (2,899.00)

Total Income $ 3,447,963.00

Where the Money Comes From:

Individual Contributions 34%

In-Kind Donations 5%

Grants 14%

Events 47%

Where the Money Goes:

R&D 74%

Patient Services 6%

Fundraising 12%

Management & General 8%

James Airey

Dorothy Airey-Shupper

Mark Allain

Sheilah Allison

Jerry Anthony

Jane Antonelli

Randy Armstrong

Betty Arthur

Jack Bailey

Patricia Bell Barnes

Roger Bauza

James Bayster

Nancy Beach

Raymond Bell

Alvin Berman

Patti Bertino

Beverly Bloom

Bob Blum

Laura Boardman

Joseph Boilini

Robert Brady

Nancy Brindisi

John Btatnian

Mary Kay Byrne-Jones

Faith Lucille Campbell

Gordon Campbell

Carl Carlson

Gordon Carney

Thomas Catanzano

Sylvia Chadis

Mary Kay Chappell-Brock

James Chisholm

Ingrid Cibuls

Colleen Clary

Marjorie Conley

Sue Cookson

Carol Lee Cordes

Francis Cronin

Dolly Crowell

Dorothy Cunningham

Walter Cunningham

Carl Cura

Frank Dabartolo

Robert Dake

James Dalthorp

Alston Daniel

Jack Darcy

Richard DeJong

Emilio Delgadillo

Laura Diamond

Arthur Diggs

Bryan DiMaria

David Dorfman

Frances Duff

Anne Dunphy

Eileen Dunphy-Rear

Joyce Ebner

Bruce Edwards

Ann Egnor

June Eisenberg

Larry Ellis

Sue Elston

David Eltschlager

Alice English

Glenda Evans

John C. Farie

Jim Fitzhenry

Erin Ford

Stephen Formica

DeeDee Fornengo

Millie Fouse

Colman Fram

David Paul Freed

Carolyn Freeman

Peter Ganzel

Marie Garratt

Paul Gerbick

Jeff Gilbert

Hilda Glassman

Joan Gluck

Greg Goldberg

Herbert Goren

Jeanne Gosland

Frank Graham

David Green

Ken Green

Steven Greenfield

Rick Guttenberg

Doris Hable

Donald Hacker

Kyle Hahn

Thomas Hall

Oscar Hampton

Gail Haynie

Kenneth Heitkamp

Harold Hencke

Ardis Hendricks

Ted Hibson

Mary Kay Hoaglano

William Hofecker

Jack Hoffman, Jr.

Holly Hofmeyer

Patty Holdener

Paula Horvath

Irving B. Hoskins

Nicholas Howell

Will Hubben

Anne Marie Huizdos

Norman Hussey

Betty Jefferson

Linda Jenkins

Sally Johnson

Theresa Johnson

William Johnson

Agnes Jordan

Jeffrey Julian

Mark Kalousidian

Robert Kane

Carol Kaner

Erna Kelley

Oksoo Kim

Janit Kirkpatrick

Trude Klugman

Connie Knell

Walter Knopp

Fannie Kremen

Ruth Kulow

Gary LaFontaine

Ruth Lamb

Mary Kay Lampiasi

Gail Landres

North Lang-Pober

Jim Laughlin

Lenore LeBeau

James Lewis

Terry Lewis

James Lisle

Dorothy Logue

Jennifer Lopez

Edward Love

Bernice Lyall

Barbara MacDonald

Elliot Macht

William Maher

Martin Mangan

Hugo Martins

Chuck Maylen, Jr.

Michael McCabe

Jay McCarthy

Lucilla A. McCarthy

Keith McCormick

Jim McKay

Tom McMillan

William L. McNamara III

Sandy McReel

Ken Melanson

Stephen Milne

Barbara Moeckel

Daniel Montes

Laurie Moore

Francis Moynihan

Evelyn Mulso

Robert Murtaugh

Allan Nelson

Beatrice Newhouse

Jennifer Nichols

Andrew Nodaros

Margaret O’Grady

Katherine O’Hanlon

Jim O’Shea

Marion Oak

Judith Oakley

Alice Ondo

Robert Osteryoung

Raymond Otte

Joe Pagliuca

Bob Palguta

Eileen Parks

Marion Parnell

Oscar Pearson

Art Peck

Sonny Piekarski

Shirley Pierse

George Priest

Howard Prisock

Richard Pugh

Debprah Radam

Eva Raffagnello

Jim Raspanti

Randy Refosco

Mary Elizabeth Revere

Christine Rich

Jeanne Ridings

Nick Riley

Patricia Roberts

Gladys Roganti

Charles Rouse, Jr.

Jon Russell

Velda Schandler

Pauline Raine Scheck

Theresa Schilling

Stan Schroeder

John Schulz

Sharon Scuzzo

Sid Sharpstein

Walter Shaw

Jeff Shertinsky

Paul Shields

Carl Shope

Mary Lou Schwartz

Joseph Siecka

Beryl Sill

William Sinton

Jerry Slagle

Patricia Smith

Richard Spinelli

Kevin St. George

Sharon Stahly

Angela Stark

Jimmy Starnes

Marty Stayer

Scott Stein

Bernard Stollman

Joyce Stout

Sheryl Strausbaugh

Jerry Stubbs

Edmond Sullivan

Ed Swain

Helga Switzler

Nikki Tal

Herbert Tatelman

Kathleen Teasley

Marjorie Teuler Tucker Bayer

Robert Tripple

Jeff Ureel

Fabien Vickrey

Ernest Wallengren

Wilbur Walworth

Madonna Warren

Jennifer Webb

Pookie Weprin

Leonard White

Mike Wiley

Jonathan Wirtshafter

Peter Wise

Carol Withrow

Elizabeth Wolff

William Worthy

Kate Wroten

David A. Young, Sr.

memorials

ALS TDF acknowledges the following individuals who received gifts made in their

memory during 2004. Our staff extends our deepest sympathies to their families

and friends who continue to fight ALS even after their loved ones’ death.

Governors’ Circle$25,000 - plus annually

ALS Family Charitable Foundation, Inc.

Anthony Tucker Fund

Celegene Corporation

DeeDee Fornego Fund

Friends for Faye

Jennifer Huntington

InSource Services, Inc.

Jenny Stoddard Fund

Ken Melanson’s Quest for a Cure

Larry Ellis Fund

James Mahan

Matt Dowd Fund

The Michael W. McCarthy Foundation

Nutter, McLellan & Fish

Jonathan Orloff

Pittsburgh Families Efforts

Mark Reed & Daria Ilunga

Ride for Life

Scott & Amy Peters Fund

John & Iola Sobeck

Stanfield Family ALS Fund

Ternet Friends Fighting ALS Fund

The James & Alice McGonagle

Charitable Fund

The Jeff Julian ALS Foundation

Vanguard Charitable Endowment

Program

William & Elizabeth Rieth Charitable

Foundation

Directors’ Circle$10,000 - plus annually

Adelard A. and Valeda Lea Roy

Foundation

Aventis Pharmaceuticals

Carl Tanner Fund

Chase Merchant Services, LLC

Connecticut Friends for ALS

Research

Cubby Cronan Fund

Cumberland Community

Foundation, Inc.

David Green Fund

Dean Adraktas Fund

Dick Douglass Family Effort

Elliot Macht

Fiduciary Charitable Foundation

Elizabeth Folger

Foundation for the Carolinas

Glass Systems, Inc.

GlaxoSmithKline Foundation

Golf & Ski Warehouse, Inc.

James Allen Heywood

Frank William Hirt

HMS Host Invitational

JELD-WEN Tradition Foundation

Jewish Communal Fund

Jim & Susan Airey ALS Fund

Jim Raspanti Fund

Johnson & Johnson

Gail Kendall

Rubin & Debbie Kuznitsky

William & Betsy Leitch

Mary Liebman

Marie Garratt Memorial Fund

MasterCard International

Stephen J. McKendrick

Keith & Jill Melanson

Milton Wruble Foundation

Philanthropic Fund

Nashawtuc Charities, Inc.

Norman O’Connor

Peggy Lanza Fund

PGA TOUR, Inc.

Philips Lighting Co.

Barrett Ranson

Tom Ritchie

Roizman Development Inc.

Rubin Koznitsky Fund

Scott Stafne ALS Research Fund

SouthTrust Bank

St. Hubert’s Knights of Columbus

Brian & Janine Stanfield

Steve Carlin Fund

Steve Lewis Fund

The Thorson Foundation

Gino & Bernadette Torretta

Suzy Vogler

Wachovia Corporation

Walter Knopp Fund

William Weldon

Woodbine Bend Inc.

Associates’ Circle$5000 - plus annually

Marilyn Adams

Becton, Dickinson and Co.

Chester Cadieux

Cenveo Printing

Charles River Laboratories

Robert Clausen

Control Motion Systems, Inc.

Donna Dake ALS Research Fund

Erie Insurance Company

Ben D. Estes

Fidelity Charitable Gift Fund

Fidelity Information Services

Russell Foszcz

Foxwoods Resort Casino

Garner Environmental Services

Carol Ann Garratt

Amy Goldberg

Malcolm Goodridge

Hamilton Hughes Design

Bethel Kean

Kellogg Capital Group, LLC

Audrey Kim

Kathy Knopp

Gregory Lanza

Bill Leahey

Lonza Biologics

MacDonald Illig Jones & Britton LLP

Margolis Edelstein

Masterpiece Homes, Inc.

Pfizer Foundation Matching Gift

Program

Polo Ralph Lauren Foundation

Frederick & LuAnn Rheeder

Patricia Roberts

Alvin & Ruth Siteman

Teaching to Fight ALS

The Alfred & Adele Davis Academy

The Kirk & Megan Kellogg

Foundation

Olson ALS Foundation, Inc.

The O’Reilly Foundation

United Way, Inc.

Wayne Asphalt & Construction

Co., Inc

Will Hubben ALS Research Fund

Benefactors’ Circle$1000 - plus annually

A.L. Howes Agency, Inc.

Abbott Laboratories Fund

David & Amy Abrams

Adesa Impact USA Central Office

Barbara M. A’Hearn

AIG Matching Grants Program

Susan Airey

Ayad Alhadi

ALS Association - Bay Area Chapter

ALS Association - West MI Chapter

Altria Group Inc.

American RE

Anheuser-Busch, Inc.

Gebran & Suzanne Anton

J. Kevin & Pamela Appleton

John & Diana Appleton

Colin Armstrong

David & Susan Arnold

Arrest ALS Golf Event

Michael & Jean Artin

Russell & Carol Atha

Atlanta Classic Foundation Charities

Robert & Donna Aul

Auto Body Images, Inc.

B & G Restoration, Inc.

Barr Foundation

Steven & Linda Bauersachs

Terry & Carol Baughn

Bear, Stearns & Co. Inc.

Mike & Lisa Beauvais

Thomas G. & Mary Becker

William & Linda Becker

Aileen Behm

Bell South

Founders’ Circle$100,000 - plus annually or $1 million or more cumulative giving

+ Alex & Brit d’Arbeloff

+ Anonymous Foundation

+ Beatrice P. Delaney Trust

+ Driving 4 Life

+ Fran Delaney Fund

+ Hope Happens

+ Ronya Kozmetsky

+ Mary Lou Krauseneck Fund

+ Edward W. Scott Jr.

+ Stephen Heywood Fund

+ Stephen Milne Society

Our Team: The members of the Stewardship

and Communications staff maintain

relationships through ongoing

outreach to ensure long-term, mutually

rewarding affiliations.


Benfield Florist

Birtcher Anderson Properties

Marc & Lois Blais

Blanch, L.P.

Frank H. Blatz

Joe & Jo Ann Blazek

Bodell, Bove, Grace & Van Horn

Body-Borneman Associates Inc.

Bono’s of North Florida Inc.

Bovenzi, Inc.

Bradbury Family Charitable

Foundation

Scott and Mary C. Brady

Jack & Karen Brandenberg

Donald H. Brodie

Budow and Noble, P.C.

James Burdine

Michael Byrne

Café Buon Gustaio of Hanover, Inc.

Dick & Peggy Campion

Thomas & Nancy Cannon

Capezio Contractors, Inc.

John Carli

Carol Schnitzer Lewis

Mike Carpenter

Cattel, Tuyn & Rudzewicz, PLLC

Ann Chisholm

Ric & Therese Chouinard

Christmas Barn

Jerome & Pam Circo

Chad J. Clay

ClubCorp Service Center

Gregory D. Coates

Coilcraft

Jerry E. Colton

Complete Environmental

Products, Inc.

Computer Leasing Company of

Michigan

Computer Sciences Corporation

Consolidated Services Group, Inc.

Stephen & Bernadette Cooper

Country Club of Fairfax

Robert H. Cox

Cozen O’Connor Attorneys

Stephen H. Crandall

Ben & Heather Crane

David & Mary Critchlow

Dominic & Pamela Cruz

Ruth H. Cunniff

Gary and Donna Dake

Dalbello Sports LLC

Datamann, Inc.

Davic Inc.

David Bullard Fund

Sal Davide

George E. Davis

Davis-Vandenbossche Agency, Inc.

John Day

Deane Jewell Team

Deerwood Rotary Charity Fund

DeStefano Custom Builders, LLC

Developers Three, Inc.

DGA Builders, Inc.

Diageo North America, Inc.

Robert Dibble

Steven G. Dickman

Dan Dickson

Diversified Therapy

Ralph & Barbara Dobson

Charles Dolan

Stephen & Pam Douglass

Greg & Julie Dowd

Ted and Julie Drummond

Duane Morris LLP

Dulin, Ward & DeWald, Inc.

Peter Dunn-Rankin

E.L. Webster Insurance Agency

Eastman Gelatine Corporation

Gary & Joan Eichhorn

Jency Eldridge

Morton Eldridge

Elite Sales, Inc.

Energy Service Investment Corp.

Enterprise

Enterprise Rent-A-Car Company

Greg & Connie Entwistle

Environmental Safety & Health

Consulting Service

Pardee Erdman

Erie Indemnity Company

Ernest Maier, Inc.

Ernst & Young LLP

Katharine C. Evans

EverBank

Evergreen Youth Foundation

Ziggy & Suzanne Ezekiel

Factory Mutual Insurance

Company

Bill Fenwick

First American Title Insurance Co.

Fisher Printing, Inc.

Jack Flanagan

Forry, Ullman, Ullman & Forry, P.C.

Theresa Foster

Foxwoods Resort Casino

FPIC Insurance Group, Inc.

Tom Fraehmke

Frank Maynard Fund

Ronald Frechette

Kathleen Freed

Nathan Friedlander

Paul & Nella Fulton

Gateway Motors, Inc.

Norman Gavin

Glen-Gery Corporation

Global Imaging Systems, Inc.

Brian & Veronica Glynn

Lou & Celia Star Gody

Ed Golden

Goodrich Foundation

Tyson & Anya Goodridge

Louise B. Goodridge

Mark & Brenda Gordon

Great Lakes Insurance

Associates

Jean Green Oehler

Frank Hable

Janet Hagedorn

Bruce & Linda Hain

Daniel Hamilton

Thomas Hanley

Harrell & Johnson

Larry Harris

Tom Harris

Terri Hathaway

Jan & Ruth Heespelink

Edward Helquist

Henredon Furniture

Henry D. Nichols, DDS, PC

Jane Herbst

Karen Herbst

Paul & Diane Herman

John & Peggy Heywood

Carol Hickey

Lisa Hicks

Home Builders Association of

Fort Wayne

Mark Hoofman

Thomas Howard

Lynn Howle

Arthur Hoynack

Richard Hubband

George & Kathy Hughes

Gary A. Iacovelli

Indiana State Seniors Golf

Association

Infineum USA LP

Intra-Services Co.

Irmscher Suppliers, Inc.

David & Alia Isaacson

Edward Jacobs

Mark & Kathy Janssen

Jeff Repetto Fund

Jim and Susan Airey ALS Fund

Jimmy Walker Coffee House

Joe Shambo Fund

John R. Lyman Company

Frank & Elizabeth Johns

Keith Johnson

Frederick & Jennifer Jordan

Bill Jorgensen

Howard Kelley

Ken Browne Productions

Kim Wickers Jar

Kate Kirkpatrick

Jeffrey Klein

Konica Minolta Business

Solutions

Harold & Mary Lou Krauseneck

Landers Management LLC

Dan & Sharry Langdale

Robert & Kimberly Lanza

Larry Manes Fund

Maureen Laughlin

Laura Gould Fund

Jane Lawlor

Bill Leahey

Bob & Mary Leisure

David Lewis

Rebecca Liebman

Lonnie Lief

James & Katherine Limke

Litigation Solutions, Inc.

Thomas S. Locke

Brian Loeb

Joanne B. Long

Los Angeles Community

College District

Luc Blais Fund

George Lucore

Jeffrey A. Ludrof

Mike & Elaine Lutsch

Stephen Lyon

Bill & Diane MacDonald

Todd MacDonald

David MacTavish

Tim & Denise Madigan

Maisel Brothers Inc.

Marshall & Swift

Martin Family Trust

Masonry Institute of Maryland, Inc.

Maureen & Keith Mayo

Jim & Sally McAlpine

McCabe Insurance Associates, Inc.

McCarthy Wilson

Laura McConnaughay

Edward McGahan

McGrath Builders, Inc.

Robert McKenna

Mary Martha McKinley

Steven & Leslie McMillin

Mellon Bank, N.A.

Mercyhurst College

Meredith Corporation

Merrill Lynch

Merrill Lynch & Co. Foundation, Inc.

Joseph Michalowski

Dan Miller

Samuel & Anna Milligan

Milliren Insurance Agency

Minnick Concrete Products, Inc.

Misc. Family Fund Events

Guy Mitchell

James H. Mitchell

David Mobley

Montcalm Golf Club

Morsches Lumber, Inc.

Evelyn Mulso

Richard Munn

Hank & Kim Nichols

Jonathan & Eileen Nicholson

Stacey Nicholson

North American Operations

Dan & Julie Nowicki

NV Homes

Jim & Mary O’Connor

Martin & Mary O’Connor

Michael & Holly O’Connor

Patrick & Nancy O’Connor

Philip & Jennifer Ogden

Neil Oxman

Pat & Tony’s Inc.

Paul Gerbick Fund

Permian Basin Landmen’s

Association

Peter E. Johnson Building

Supplies Inc.

Seaver Peters

Phoenix Realty Group, Inc.

Pinnacle Painting

PNC Bank

Polachek & Associates, P.C.

PQH Architects

Precision Heliparts, Inc.

Jeffrey Preuss

James N. Pritzker

Private Retreats

Katherine Probst

Pro-Claim Plus, Inc.

Pro-Cut International Ltd, LLC

Bryan & Sally Putt

Cynthia S. Rasp

Connie Raspanti

Edward Raynor

Bob Regener

Reichert Foundation

Paul B. Repetto

Richard E. Rhoad

Rhodes Environmental, Inc.

Ringler Associates Eastern

Ohio, Inc.

Robb, Leonard & Mulvihill

Michael & Stacey Roberts

Denise Robertson

Philip & Rosanne Rodilosso

John & Margaret Roll

Rollins, Smalkin, Richards,

& Mackie

Roth Marz Partnership, P.C.

Walter Rothfuss

Safelite Auto Glass

SAFELITE Glass Corp.

Sand Creek

Sawgrass Country Club

Jim & Carol Schebil

Stephen R. Scholl

Stephen B. Schroeder

Bob & Cynthia Schuneman

Sea, Ltd.

Thomas E. Seiffert & Faye Magnesun

Servpro of Wheaton/

Kensington, Inc.

Shar Systems, Inc.

Sharon Stahly Fund


William Sharp

David Shatto

Michael Shaw

Randall & Linda Shepard

Virginia Shields

Richard & Claire Shonter, Jr.

Silverfield Development Co.

Christopher Smith

Stephen R. Smith

Mark & Vicki Smucker

Mark & Mary Sobeck

Mark Solow

Somerset Patriots Baseball Club

Sons of the American Legion

Valerie Sontrop

Southcoast Capital

Management Corp.

Southside Rotary Foundation

Southwest Signal Engineering

Richard & Janet Sprague

Matt Spruck

St. John’s Preparatory School

St. Mary’s Insurance Agency, Inc.

Kirsten Stafne

Amanda Stanfield

Steve Gribble Fund

Stewart, Brimmer & Company, Inc.

Jenny Stoddard

Summit City Investments

Superior Plumbing, Inc.

Barry & Elaine Taylor

Walker Taylor

Techware Distribution

Jane L. Ternet

Terry L. Ternet

The Brannan Family Foundation

The Carter Family ALS Research

Fund

The Cass Family Foundation

The Dunphy Sisters’ Fund

The F&M Bank & Trust Company

The Howard Research &

Development Corp.

The Jacksonville Bank

The John S. & Amy S. Weinberg

Foundation

The Pineapple Corp. of North

Florida

The Simms Insurance Agency, Inc.

The Tradefair Group, Inc.

Robert & Dany Theuerkauf

Heather Thomas

Steve Thomas

Michael Thompson

TK Sportswear

Joe Torcivia

Tower Bank

Peggy L. Trenkner

Howard & Ann Trerice

Alex K. Treves

Robert I. Trevino

UBS Foundation USA Matching

Gift Program

Ultimate Power LLC

University of Arkansas

Foundation, Inc.

V.W. Brown Insurance Service, Inc.

Karen Valperga

David P. Van Sleet

Vellumoid, Inc.

Venus

E.J. Victor

William Vogeney

James Voyles

Jeffrey & Joleen Wangler

Patricia Ward

Blair Warner

Beverly F. Watson

Watson Wyatt & Company

Wedgewood Investors, Inc.

Edward J. Weise

Dar & Dot Wiekamp

Juli Wilkerson

Christopher Williams

Robert & Denise Williams

Wilson Sporting Goods - Golf

Basil & Judi Witt

Jonathan Wolff

Wolfmom Family Fund

Becky A. Woolman

World Reach, Inc.

Harry & Effie Yamano

Al & Joann Young

Deborah G. Youngblood

Friends$500-plus annually

A.F. Szabo Insurance Agency, Inc.

A.J. Silberman & Company

AAA Flexible Pipe Cleaning Co.

John Abele

Andrew Achimovic

Robert & Kathleen Achimovic

Daniel & Cathy Acklin

Action Check Cashing Corp.

Michael Agostino

Alex R. Szeles, Inc.

All Sports Bar & Grill

Keith Allison

Herb & Cooky Alpern

American International

Removals

Amtex Steel, Inc.

Curt Anderson

Annapolis Radiator and Body

Shop, Inc.

Anonymous

Emmanuel Antonio

Milton Arnold

Patricia Arnold

Assist 2 Sell

Richard & Marcia Aston

ATZ Law Office, LLC

Joe & Patie Augugliaro

Skip & Beth Autry

Axiant Computer Technology

Pauline A. Backstrom

John Bankhead

William Barry

Thomas Bascetta

Charlie & Colleen Batcheller

BBG Insurance Restoration

Bealine Service Company

Steve Beard

Matthew Beary

Helen Becker

Andrew & Jennifer Behm

Lenny & Karen Behm

William M. Bell

William G. Bender

Paul & Kathleen Benick

Charles & Dyann Bennett

Tom & Camille Benson

Craig & Wendy Berens

George & Katie Berges

Best Motors

Betterworld Telecom LLC

Beverly Country Club

Blackman Kallick Bartelstein LLP

Bill Blades

Bogart & Brownell

Boizelle Insurance

Ralph Borneman

Judith W. Bowen

Robert & Lorrin Bowser

Chris & Laurie Bradbury

Scott Brady

David Brault

Linda Brickner

John J. & Elaine Brinling

Bristol-Myers Squibb

Foundation

Richard Brock

Browning-Reagle Insurance

Agency

Iris Bruhnke

Roberta Brundrett

Bryan & Mark Allain Fund

John Buccigross

Mitchell & Lois Burack

Dale Burley

Phyllis Burlingame

Mark & Sherry Burns

Dan & Joanne Burton

John Byrne

C and C Powerline

C. F. O’Connell & Sons, Inc.

John Caldcleugh

Dean Caldwell

Dusty & Annette Caldwell

David K. Camken

Michael Campbell

Robert Capalbo

Bob Carden

John R. Carnaghi

Carouna Lumber Company

CCC Information Services, Inc.

Celerity Mortgage Group, Inc.

Thomas Champion

John & Linda Chayka

Cherry Hill East Girls Basketball

Chesapeake Mill Products, Inc.

Christpher’s Limited Restaurant Inc.

Cindex Industries, Inc.

Classic Stereo-Pak, Inc.

Coca-Cola Bottling Company

Kevin & Donna Marie Collins

Combined Federal Campaign

Complete Masonary Inc.

Comp Management of Virginia, Inc.

Eugene & Anne Connell

Jackie Cook

Joe & Mary Lou Cook

Lois C. Cooper

Ron & Elizabeth Cooper

David Cory

Steve & Pat Crandall

Creamer Insurance Agency

Creative Visualization, Inc.

Linda Criniti

Joan Cronan

Michael Cronan

Peter Cronan

Frank Cupo

D. Watkins & Co., Inc.

Mike Daley

David Eltschlager Fund

Anna Davide

De Lage Landen

Peter & Christine de Steiger

Fred & Ann Dean

E. F. Dehnert

Patrick A. Dempsey

Steven W. Dempsey

Mary Demsky

Kathryn B. Des Chenes

Russ & Leigh Devore

Sandra M. DeWald

Armand Dias

Alan W. Diercks

Michael Dooley

James & Erika Dore

Richard & Vivian Douglass

Henry & Cynthia Dowd

DPS

Tim & Karen Driscoll

Fred Duemling

Dennis & Holly Dulac

Jay & Joleen K. Duprey

Dynalectric Company

Eden Golf

Edison Electric Co. Inc.

EDS

Educor, Inc.

Brian & Laurie Edwards

David Edwards

Evelyn Elliott

Gaylord & Griselda Ellis

Maureen Ellis

Elsroad Trim Corporation

EMC Corporation

Dennis & Fredericka Emory

Erie Community Foundation

George Evarts

Ewing, Hines & Associates

Insurance

F & N Bookkeeping Services

John Fahnestock

John Fannin

Norman & Lucie Faramelli

Michael Fay

Bill & Terri Featherstone

Felderman Design-Build

Edith Fenton

Fidelity Closing Services, LLC

First Guaranty Bank & Trust Co.

First Response, Inc.

Catherine A. Fisher

Fishery Products International

Richard Fitzgerald

Five Star Basketball Camp

Fixed Return Investments of

Connecticut

James Flynn

FMC Technologies, Inc.

Ruth A. Ford

Patricia Formica

Richard J. Freeland

David C. Friedrich

Frye Insurance Associates, Inc.

Sarah Fuller-Lessard

Jim & Deanna Gage

Phil Garcia

Gargano Appelbaum & Horan Inc.

Lynn & Sharon Garner

Gate Petroleum Company

Susan Gates

Skinny & Cathie Gawel

General Shale Brick

Dwight & Ros Gentry

Geosearch, Inc.

Stephen & Carol Geremia

Libby Gerlach

Getchell Professional

Association

David & Naomi Gilkerson

Hannah Golub

Robert Gonnam

Lisa Goren

Scott Govoni

Nadine Gramling

Thomas Grealish

Mickey Grundhofer

Bruce & Joyce Guseila


H.T. Brown Real Estate, Inc.

Joseph Haas

Ron Hallagan

Harkins Builders, Inc.

Micky Harrison

Hartley Precast Inc.

Ken Hawkins

Karen L. Hayden

David Hayes

Tom Henry

Michael & Gail Hernalsteen

Christian & Maryann Herrmann

Hickory Foods, Inc.

Kathleen Hinkelman

Virginia Hoffman

Hogan Communications, Inc.

David A. Hopper

Howard Community College

Jeff & Melissa Hruby

Hyattsville Auto Body, Inc.

Rick Iceberg

Kaveh Ilkhanipour

Illinois Tool Works Foundation Ims

Insurance Auto Auctions

Insurance First

Isaac Heating & Air Conditioning

J.E. Schenk & Associates

Jack Martin Insurance Group

Jacksonville Chapter - FL

Mortgage Brokers

Association

John & Kristen Jacobs

Jean Angell Fund

JEMS

Jerry W. Bailey Trucking, Inc.

Alan & Karen Jewell

Douglas Johnson

Tom & Donna Johnson

Jann Johnston

Joseph W. McCartin Insurance, Inc.

Roy Kahn

Marie L. Karl

Gordy & Patricia Kennedy

Tim Kernan

Key Kleaning Service, Inc.

Key Maps, Inc.

Bruce P. King

Al Klugman

Todd Knabb

Ron & Amy Kodl

Ben & Mary Koehler

Koons Ford of Annapolis, Inc.

John & Mary Anne Kozak

KPMG LLP

Michael J. Krahe

Phil Kramer

Thomas & Jordan Kraus

Christine Kumiega

Ralph LaBarge

Don LaBelle

Gerald LaMalfa

Clem Lamarre

Lambertson Development

Vicki Lamont

Barbara K. Lancia

Michael & Kathleen Langen

Larry & Lynn Larrabee

Thomas Lavelle

Sharon J. Lavigne

Jim & Joan Layden

Mark Leander

Nelson & Nancy Leenhouts

Bob Lendzion

Patricia M. Ley

Richard List

Robert & Cynthia List

Brian & Julie Long

Jim & Gloria Loria

Charles & Jacalyn Lott

Lower Flathead Valley

Community Foundation, Inc.

Randolph Luck

Kathryn Lundeen

Niall Lynagh

Herbert L. & Suzanne S. Lynskey

Hilda Lyon

Dave MacTavish

Ken & Debi Madeleine

Norma Magneson

Daniel Mahoney

Chris Maltinsky

Marflax Corporation

Marine Spill Response

Corporation

William H. Martin

Martinsburg Smallwood & Small

Insurance, Inc.

Mark & Laura Mastracci

Mark Matthews

Gary & Martha Maxwell

McCormick & Priore, P.C.

McCutcheon Ins.

Tom & Judy McHugh

Kenneth & Nanci McLaughlin

Diane T. McMeekin

John & Michelle McNulty

Mechanical Engineering &

Construction

Louis & Jill Behr Medved

Lee Mercier

Mervis Diamond Corporation

Michigan Neurology, PLLC

Microsoft Matching Gifts

Program

Minkoff Company, Inc.

Pedro & Lauri Miro

Mission Fish

Melba Moeck

Roger Mohr

Christian Monrad

Monroe Wheelchair

Moon Lighting Electric Service, Inc.

Mooney Aircraft Pilots

Association

Bill & Margery Moore

Timothy Moore

Kurt & Elizabeth Morgan

Ian Mulhinch

Edward Mullen

Mark Mullins

Yolanda Munoz

Bob & Angie Myers

Karyn Nader

Simon & Val Nader

John & Paula Nehra

Philip Nehra

New England Air Conditioning

Newsletter Exchange, Inc.

Niles, Barton & Wilmer, LLP

North Central PA Golf

Association

Howard Nott

Nova Ocean Marine, Inc.

Mark & Susan Nowinski

NSR Electrical, Inc.

Rudy Nucci

Jim & Ginny O’Connor

Patrick D. & Mary O’Connor

Patrick O’Dea

Jeannette Oglesby

Michael O’Hare

Charles Ohl

Marty & Jane Oleszkowicz

O’Loughlins Restaurant

Norman Olson

Marc & Lynn Ott

Maryann Pairitz

Paul Davis Systems of Baltimore

Perdue Office Interiors

Scott Peters

Philip Grace Jr. Stone Masonry

Curt & Gerry Pindler

Douglas Pirnie

Potomac Valley Brick & Supply Co.

Steven Potter

Princess Jewelers

Alex & Judy Pursley

Quality Care Cleaning Service

R. C. Olsen Cadillac, Inc.

Ernestine Raclin

Jeff & Lauren Radke

Paul & Jane Ralser

Albert & Audrey Ratner

Joan Raymond

Regina Rear

Creighton & Kerry Reed

Jeffrey Renelt

Dominic & Maryann Henry Rice

Rich Osterman Electric Co.

RMG Consulting, LLC

Michael & Janet Roberts

Andy & Kate Robinson

Ronald S. Bunt, Inc.

Joann Ross

Russell & Richardson Family

Foundation

S.I. Restoration

Rich & Gayle Santora

Adel & Leticia Sarofim

Denise Scheberle

James J. Schebil

Laura J. Schenkel

Cindy Schmidt

Shaun Schneider

Eldon & Lois Schoeber

David Scott

ServiceMaster

Anthony Sessa

Douglas Sharon

Douglas & Nanci Sharon

Sherburn Screen Printing

Michael Sheridan

Shooters Sports Bar

Gerald & Carolyn Shurb

John Simpson

Robert Slavin

David Slingsby

Smail Associates, Inc.

Edward Smith

Kurt Smith

Smith-Bell Petroleum, Inc.

Gregg Smolenski

Alan & Terry Snell

Sniteman, Inc.

Kurt M. Snouffer

Eric W. Snyder

Mallon Snyder

Peter Sollimo

Sorbent Products Co., Inc.

Alan & Roz Spier

Gerry & Judy Stafne

Tim Stahly

Les Stanfield

Statland & Katz, Ltd.

Stellers Gallery

Stenner

David Stephens

Steve Fowler Fund

Kurt & Joey Stiver

Glenn Strier

John F. Sullivan

Bruce Taylor

Kirk Taylor

Mary Ann Teetor

Jeff Tester

The Clark Agency

The Landreth Family Foundation

The Math Works, Inc.

The Needlers Inc.

The Schroedl Co.

The South Financial Group

The Vitale Caturano & Co.

Foundation

The William Tell & Karen Tell

Foundation

Michael W. Thomas

J. Earl Thompson

Chuck & Jacqueline Thorne

Three Village Kiwanis Club

Lila Tickman

Margaret Tiesler

Kevin & Karen Till

TMR & Associates, Inc.

Mark Trabucco

Cheryl Troiano

Trude Klugman Fund

John Tudor

U.S. Insurance Services

UBS Financial Services Inc.

Steven Umin

United General Title

Insurance Co.

Universal Field Services, Inc.

Mike & Betsy Useem

Joanne Valente

Jeff Valperga

Jan & Linda Van Gorder

Barbara Van Winkle

Jonathan Vandenbossche

Russell & Donna Vanderslice

Susan Vanek

Daniel Vaughan

Gerard Verbeek

Glenn & Monica Voorhess

Walter & Karen Walburn

Scott & Jackie Wallace

Jay & Pat Walsh

Jonathan Walters

Ward-Boland Associates, Inc.

Ned Waters

Douglas & Susan Watts

George Webb

Wellesley College

Doug Wenner

Donald & Connie Wertz

WESNIC

West End Management Inc.

Eric & Amy Whipple

David White

Dominic White

George & Betsy Whitehead

Charles Whitfield

Jeffrey Williams

John Wilmarth

David & Ellen Wilson

David L. Winebrenner

Roger & Susan Wit

Donald Withrow

James & Lois Witkowsky

John & Michele Wolfsberg

Wolfson Family

Frank J. Wood

Gary Worley

Jack E. Yahne

Young Chevrolet Oldsmobile

Cadillac, Inc.

Timothy Zaro

Robin Zon

Sandra Zoolakis



board of directors

Spiros Jamas, Sc.D. , Chairman

George M. Hughes, Clerk

Keith P. Melanson, Treasurer

Dennis A. Ausiello, M.D.

Steve C. Fowler

John B. Heywood, Sc.D, Ph.d.

Jennifer M. Huntington

David Searls, Ph.d.

scientific advisory board

Harvey Lodish, Ph.d. , Chairman

Robert Brown Jr. , M.D. , Ph.d.

David E. Housman, Ph.d.

Ken S. Kosik, M.D.

Peter T. Lansbury, Jr. , Ph.d.

Hidde Ploegh, Ph.d.

Hazel L. Sive, Ph.d.

Documents

Combined 2004 Annual Report & Financial Statement