Embed Size (px)
Citation preview
MACHEREY-NAGEL GmbH & Co. KG · Neumann-Neander-Str. 6–8 · 52355 Düren · DeutschlandFrankreich:MACHEREY-NAGEL EURLTel.: +33 388 68 22 68Fax: +33 388 51 76 88E-Mail: [email protected]
Schweiz:MACHEREY-NAGEL AGTel.: +41 62 388 55 00Fax: +41 62 388 55 05E-Mail: [email protected]
Deutschlandund International:Tel.: +49 24 21 969-0Fax: +49 24 21 969-199E-Mail: [email protected]
www.mn-net.com
www.mn-net.comMACHEREY-NAGEL
EN ISO 9001: 2008ZERTIFIZIERT
USA:MACHEREY-NAGEL Inc.Tel.: +1 484 821 0984Fax: +1 484 821 1272E-Mail: [email protected]
. . . we Meet your Needs
Columns and suppliescatalog
HPLC GC TLC
SPE and Flash Syringe filters
Vials and caps
MA
CH
EREY-N
AG
EL · Chrom
atography
www.mn-net.com
Chromatography
MACHEREY-NAGEL · Company profile
Since1911MACHEREY-NAGELhasrepresentedhighquality,innovationandreliabilityinchemicalandbio molecular analysis. Friendly expert advice for our highly valued customers as well as outstanding product qualityhavebeenthecornerstonesofourcorporatesuccessformorethan100years.CEOC.Wagner,thegreat-granddaughterofthecompany’sfounder,hasbeenmanagingtheenterprisesince2000.Our product ranges:
Filtration Rapid Tests Water Analysis Chromatography Bioanalysis
Dedicated from the very first: Milestones of Chromatography at MACHEREY-NAGEL
0 10
160 278 328 370
20 30 40 min
°C
1 2
3
4
56
7
8
1952: MNlaunchesthefirstproducts for paper chromatography. In the sameyear,MartinandSynge receive the Nobel Prize in Chemistry for the development of partition chromatography.
NUCLEODUR® NUCLEOSHELL®
1961: MACHEREY-NAGELbecomes one of the pioneersinTLC.
1970: Expansionoftheproduct range by column chromatography
1974: NUCLEOSIL®·oneofthefirstsphericalHPLCsilicasleadstoour core competence in silica technology
1994: OPTIMA® capillary columns for optimum GC separations
1987: CHROMABOND® columnsforSPE
2002: NUCLEODUR®
high purity spherical
silica forHPLC
2011: NUCLEOSHELL® core shell silica for highest efficiencyinHPLC
1982: firstfusedsilicacapillarycolumns for GC
Chromatography
MACHEREY-NAGEL on the internet
Visit our Chromatography pages
www.mn-net.com
Productinformation·alwaysup-to-date ChromaNews Jobopportunities Materialsafetydatasheets Free application database with about 3000 chromatography applications
www.mn-net.com
Chromatography
Catalog contents
Solid Phase Extraction and Flash chromatographyCHROMABOND®phasesandaccessoriesforSPE 1–52High-throughputSPEandFlashchromatography 53–64
Sample clarificationCHROMAFIL®syringefilters 66–76
Vials and closuresVials and closures 77–103Autosampler compatibility 103–108
Liquid chromatographyColumnsforHPLC 110–197Packings for liquid chromatography 198–206
Thin layer chromatographyPlates,kitsandadsorbentsforTLC 208–234
Gas chromatographyCapillary columns for GC 236–281ReagentsforGC 282–291Accessories for GC 293–297
AppendicesProduct and subject index, index of reference numbers, trademarks, USP lists
298–327
Sample preparation
New products for sample preparation
CHROMABOND® HR-Xpert your way to cleaner samples by SPEThe professional concept of innovative RP and mixed-mode ion exchange phases for SPE
CHROMABOND® HR-X·hydrophobicPS/DVBcopolymer CHROMABOND® HR-XC and HR-XCW strong and weak mixed-mode cation exchangers
CHROMABOND® HR-XA and HR-XAW strong and weak mixed-mode anion exchangers
Now available in 2 particle sizes: standardparticlesize85µm particlesize45µm for smaller sample volumes, lower adsorbent weight and smaller elution volumes
… Order your free samples today! [email protected]
Page
10
New CHROMAFIL® filters for optimum filtration results CHROMAFIL® Combi filters Syringefilterswithacoarseglassfiberprefilter recommended for solution with a high particle load NewdimensionsandporesizesforNylon,celluloseacetateandPTFEfilters
Page 68
Vials and closures completely revised product range Largeselectionof• Crimp neck vials, crimp closures, crimping tools• Screw neck vials and screw closures• Special vials and closures Highqualityproductsatanequitable Pag
e
77
price performance ration
Welookforwardtosharingourexpertisewithyou: [email protected]
www.mn-net.com
HPLC
New products for HPLC
NUCLEOSHELL® core-shell silica for rapid, efficient HPLC Solid core of silicon dioxide, homogeneous shell of porous silica Highestefficiencycomparedtototallyporousmaterials Poresize90Å;particlesize2.7µm(core1.7µm); specificsurface130m2/g Lowerbackpressureenablesuseon conventionalLCsystems
Page 144 Pressurestability600bar
NUCLEOSHELL® RP 18 nonpolar high density phase
Key features:• Suitable for LC/MSandHPLCatpHextremes(pH1–11)• Superior base deactivation, ideal for method development
Recommended application: Overall sophisticated analytical separations, e.g.,analgesics,anti-inflammatorydrugs,antidepressants; herbicides;phytopharmaceuticals;immunosuppressants
Page 148
USP L1
O
NH3C
CH3Si(CH3)3
NUCLEOSHELL® PFP hydrophobic pentafluorophenyl phase
Key features:• Hydrophobicphasewithalternativeselectivityincomparisonto
classical C18modifications• Separationprinciplebasedon4retentionmechanisms(polarin-teractions(Hbonds),dipole-dipoleinteractions,π-πinteractions,hydrophobicinteractions)
Recommended application: Aromatic and unsaturated compounds, phenols, halogenated com-pounds,isomers,polarcompoundslikepharmaceuticals,antibiotics;high retention of basic compounds
USP L43
F
F
F
F
F
O
H
O
Page
150
NUCLEOSHELL® HILIC zwitterionic phase
NPC IC
HILIC
RPC
Eluent
AnalytSorb
ens
Key features:• Ideal for reproducible and stable
chromatography of highly polar analytes• Very short column equilibration times
Page 152
Recommended application: Hydrophiliccompoundssuchasorganicpolaracidsandbases,polarnatural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins
New products for HPLC
NUCLEODUR® PolarTec RP phase with embedded polar group Key features:• Excellentbasedeactivation• Suitable for LC/MSandstablein100%aqueousmobilephases• Pronounced steric selectivity
Recommended application: Exceptionalselectivityforphenolsandnitrogencontainingcom-pounds, polar compounds like basic pharmaceuticals, organic acids, pesticides, amino acids, water soluble vitamins, etc.
USP L1 and L60
Page
124
NUCLEODUR® PFP hydrophobic pentafluorophenyl phase Key features:• Hydrophobicphasewithalternativeselectivityincomparisonto
classical C18modifications• Separationprinciplebasedon4retentionmechanisms(polarinteractions(Hbonds),dipole-dipoleinteractions,π-πinterac-tions,hydrophobicinteractions)
• Suitable for LC/MS due to low bleeding characteristics Recommended application: Aromatic and unsaturated compounds, phenols, halogenated com-pounds, isomers, polar compounds like pharmaceuticals, antibiot-ics;highretentionofbasiccompounds
USP L43 Page 136
HPLC
www.mn-net.com
Chromatography
New products for TLC and GC
ALUGRAM® Xtra optimized TLC silica layers on aluminium Outstanding wettability for precise colorization results, evenwith100%aqueousderivatizationandvisualizationreagents
Excellent separation efficiency and reproducibility from lot to lot Easy and reliable cuttingduetoanoptimizedbindersystem,noflakingofsilica;nowavailableas• ALUGRAM® Xtra SIL Gwithunmodifiedstandardsilica• ALUGRAM® Xtra Nano-SILwithunmodifiedHPTLCsilica• ALUGRAM® Xtra SILGUR standard silica with concentrating zone• ALUGRAM® Xtra Nano-SILGURHPTLCwithconcentratingzone
Pages 214−218
OPTIMA WAXplus® OPTIMA® FFAPplus optimized polar phases for GC WAXplus Polar phase with improved cross-linking for reduced col-umn bleeding and better tem-perature stability
H
H
O C
n
OHH
H
H
C
Good solvent stability, extended column life-time,betterperformanceintheMSincom-parisontoconventionalWaxphases Recommendedapplication: broad ranges of analyses, e.g., for solvents and alcohols, suitable for aqueous samples
USP G16
Page
261
FFAPplus Polar polyethylene glycol phase with nitro-terephthalicacidmodificationandinnovativecross-linking
C
O
(OCH2CH2)m O
O2N
C
O
n
Good solvent stability, extended column life-time,betterperformanceintheMSincom-parisontoconventionalWaxphases, suitable for aqueous samples Recommendedapplication: FAMEs,allowsdeterminationoffreecarbox-ylic acids without derivatization
USP G35/closeequivalenttoG25
Page 263
