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©2009 Waters Corporation | COMPANY CONFIDENTIAL Core Facilities Technology Summit Columbia, MD October 27-28, 2009

Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

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Page 1: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL

Core Facilities Technology Summit

Columbia, MD

October 27-28, 2009

Page 2: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 205/10/07

Welcome!!!

Page 3: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 305/10/07

Welcome!

Logistics— Agenda

— Dinner

— Internet access

— Posters

35 attendees:— Customers

— Waters personnel

Background of Technology Summits

Page 4: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 405/10/07

Agenda – Day 1

Page 5: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 505/10/07

Agenda – Day 2

Page 6: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 605/10/07

Executive Roundtable – Wed at 8:30 am

Q&A with our Executive Team— Mark Groudas, VP of the Americas

— Dan McCormick, VP of R&D

— Rohit Khanna, VP of Worldwide Marketing

Opportunity to learn more about strategic directions

Input as to future needs and current challenges that can impact Waters’ future directions

Page 7: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 705/10/07

Facts about Columbia, MD

Planned community that contains 10 self-contained villages

Designed by James W. Rouse and opened in 1967

Population 97,200

Hotel overlooks man-made Lake Kittamaqundi.

Near NSA and Ft. Meade

The People Tree Statue is its symbol

Dinner at King’s Contrivance Restaurant

Page 8: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 805/10/07

Goals for the meeting

Share your current and future research requirements and challenges

Identify potential areas for collaboration

Provide input into our future technology development and desired capabilities

Share innovations, insights and trends with colleagues

Page 9: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 905/10/07

Our Mission

Keen understanding of our customers

Delivering innovative solutions

Ability to make a positive impact on customers’ performance

Page 10: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1005/10/07

Collaborative Partnerships

David H. Murdock Research Institute Taps Waters for Laboratory Technology Strategic Partnership Provides Advanced Technology for Groundbreaking Nutrition and

Disease Research

For Immediate Release Kannapolis, N.C., and Milford, Mass. - October 16, 2008

The David H. Murdock Research Institute (DHMRI), located at the North Carolina Research Campus in

Kannapolis, NC, and Waters Corporation (NYSE:WAT) announced today that Waters® has been selected as

the institute's primary supplier of analytical science solutions, including mass spectrometers, liquid

chromatographs and associated scientific data management software.

"We selected Waters as a partner based on their breakthrough technologies and hands-on

approach to customer service. The equipment that we've purchased from Waters is recognized as

the most sophisticated laboratory equipment available," said David H. Murdock, DHMRI founder.

"This large purchase continues the momentum we're building as a cutting-edge research facility sought after

by some of the nation's brightest scientists, and positions us well for the future."

UC Davis Pushes Limits of Infectious Disease Research with New Waters Mass Spectrometry... UC Davis Pushes Limits of Infectious Disease Research with New Waters Mass Spectrometry Laboratory SYNAPT HDMS enables advanced molecular characterization with analysis of dynamic biological structures DAVIS, Calif., Dec. 6 /PRNewswire-FirstCall/ -- University of California, Davis, and the Waters Corporation (NYSE: WAT) today dedicated the new Waters Corporation Facility for Advanced and Integrated Mass Spectrometry within Dr. Julie Leary's laboratory for mass spectrometry (MS). Prof. Leary, together with collaborators at UC Davis, UC Berkeley and Stanford University, is currently using this laboratory to study eukaryotic translation, the process by which messenger RNA is translated into proteins within the human 40S ribosome, to better understand how infectious diseases like hepatitis C and polio virus are transferred to humans.

Page 11: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1105/10/07

Keen Understanding of our Customers

Drives our innovation of new products and enhancements to current products

Drives the delivery of total solutions incorporating— UPLC

— Mass Spectrometry (Tandem, TOF, IMS, MALDI)

— Software (Applications Managers, MSe, information management, ELN, Business Intelligence Manager)

— Chemistry (sample prep, solutions for peptides, AAA, oligonucleotides, glycan analysis, intact proteins)

— Services (training courses, on site support, experts in MS and applications managers, customer support)

Page 12: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1205/10/07

Technology + Expertise

Page 13: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1305/10/07

About Waters

Established in 1958— $1.6 billion in annual revenue

— 5,000 employees with an average of 10 years of service

1,500 direct sales/service— Many were once customers

97 offices serving 54 countries

Multiple manufacturing and distribution centers worldwide

Milford, Massachusetts – Corporate Headquarters

Manchester, England – MS Center of Excellence

Page 14: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1405/10/07

About Waters

Operational Excellence

All facilities cGMP-compliant and ISO 9001-2000 certified

30+ years of manufacturing expertise

20,000 instruments, 180,000 columns, 1,400,000 parts

Consumables

Instruments

Page 15: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1505/10/07

Breakthrough Technology

1963First liquid

separations system

GPC-100

1973High-performance

liquid chromatography

M6000 HPLC Pump

1978Solid phase Extraction

Sep-Pak Cartridges

1979High temperature

GPC System

Waters 150C

1986Networked

chromatography software

ExpertEaseSoftware 1988

PC-based Chromatography

software

Maxima Software

1993Client/server

based software

Millennium Software

1995Quadrupole time-of-flight

MS

Q-Tof Mass Spectrometer

2004First

UPLC System

ACQUITY UPLC System

2006High-Definition MS

Synapt HDMS System

2008nanoTile based

separations

TRIZAIC UPLC System

2008-9XEVO MS Portfolio

XEVO TQXevo QTof

2009SFC Technology

SFC-MS Prep 100

2008Process Analytical

Technology

PATROL UPLC Process Analyzer

Page 16: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1605/10/07

Future Directions

Informatics— Consistent platform infrastructure — Data acquisition and control flexibility— Re-purposing data from multiple sources

Proteomics and biopharmaceuticals— Protein identification and screening— Protein characterization— Protein expression profiling

Create total solutions for strategic applications— Bioanalysis— Clinical diagnostics — Metabolic profiling— Environmental analysis and food safety

Page 17: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1705/10/07

Future Directions

Strong partner relations and collaborations — the key to practical innovation is a better understanding of your business and laboratory needs, anticipated future trends

Expand and enhance our existing platforms in UPLC and MS in ways that address your most pressing challenges, with solutions-based software, chemistry and services

Page 18: Columbia, MD October 27-28, 2009 - Waters Corporation · —Re-purposing data from multiple sources Proteomics and biopharmaceuticals —Protein identification and screening —Protein

©2009 Waters Corporation | COMPANY CONFIDENTIAL 1805/10/07