Collaboration with the COPDgene Group & priorities for REGRichard Martin9:40–10.00

Initiatives

• Validation of end points• Validation of real-life diagnostic criteria

where no code exists• Health care utilization and therapy in

COPD based on CT lung phenotyping

COPDgene Group

• ~10,000 COPD patients well-categorized• Unique

o CT lung phenotyping– Emphysema ±– Air trapping ±– Mixture

o Social security numberso ⅓ are black

• Medicare database (≥ 65 y/o)

COPDgene Group

• Telephone survey—symptoms • Not health care utilization• Not by CT phenotype

COPDgene Patients: real-life trials• Health care utilization by CT phenotype

o Hospitalizations– O2 use– Meds– Procedures– Other costs – ICU, etc.

• EDo As above

• Above for blacks (1/3 of sample size)• Influenza/Pneumovac vaccinations (?)

Funding

• NHLBI ancillary trials—D/C

• PharmaoBIoGSKoAZ