CLOSE ASSOCIATION OF RER AND MITOCHNDRIA

SER

RER

Hepatocyte from a hamster injected with phenobarbital

THE CLOSE ASSOCIATION OF SER. PEROXISOMES, AND MITOCHODRIA

CLOSE ASSOCIATION OF SER AND GLYCOGEN ROSETTES

Steroid hormone producing cell (interstitial cell of testes)

Adrenal cortical cell producing steroid hormones

Mitochondria typical of steroid-producing cells

DENSITY GRADIENT CENTRIFUGATION

NADPH + H+ NADP+

O2

H2O

ROH

Fe3+

RH2

NADPH CYT P450 REDUCTASE

CYT P450

R – H + O2 + NADPH + H+ ROH + H2O + NADP+