PharmacoEconomics & Outcomes News 321 - 14 Jul 2001 Clinical pharmacists reduce institutional costs A pharmacy practice model integrating staff pharmacists into existing clinical practice has ‘the potential to minimize the risks, decrease the costs, and improve the outcomes associated with drug therapy’, say Dr Todd Nesbit from Johns Hopkins Hospital, Baltimore, US, and colleagues. The model, integrating clinical staff pharmacists (CSPs) under the direction of clinical pharmacy specialists into drug selection, administration and monitoring activities, was implemented at a large tertiary-care institution in the US in 1999. Dr Nesbit and colleagues report that CSPs made 4959 interventions during a 12-month study period, which resulted in drug acquisition cost savings of $US92 076. The most frequent interventions were therapeutic consultations (1062 interventions), followed by 1003 dosage adjustments for renal function, and 678 pharmacokinetic consultations. Dr Nesbit and colleagues estimate that interventions under the CSP programme resulted in a cost avoidance of $US488 436 from avoided adverse drug events (ADEs). * They say that the CSP programme cost $US187 852 in 12 months, ** representing a net value to the institution of $US392 660 in ADE cost avoidance and drug acquisition cost savings. Dr Nesbit and colleagues based their economic findings on a literature-based cost estimate of $US5006/ADE. In a sensitivity analysis they found that economic benefits continued to exceed costs until the estimated cost of an ADE dropped to ≤ $US981. * Cost avoidance was calculated for each intervention by multiplying the probability of an ADE in the absence of an intervention by the estimated cost of an ADE. ** cost of equipment plus practitioner salaries and benefits Nesbit TW, et al. Implementation and pharmacoeconomic analysis of a clinical staff pharmacist practice model. American Journal of Health-System Pharmacy 58: 784-790, 1 May 2001 800861242 1 PharmacoEconomics & Outcomes News 14 Jul 2001 No. 321 1173-5503/10/0321-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Clinical pharmacists reduce institutional costs

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PharmacoEconomics & Outcomes News 321 - 14 Jul 2001

Clinical pharmacists reduceinstitutional costs

A pharmacy practice model integrating staffpharmacists into existing clinical practice has ‘thepotential to minimize the risks, decrease the costs, andimprove the outcomes associated with drug therapy’, sayDr Todd Nesbit from Johns Hopkins Hospital,Baltimore, US, and colleagues. The model, integratingclinical staff pharmacists (CSPs) under the direction ofclinical pharmacy specialists into drug selection,administration and monitoring activities, wasimplemented at a large tertiary-care institution in the USin 1999.

Dr Nesbit and colleagues report that CSPs made 4959interventions during a 12-month study period, whichresulted in drug acquisition cost savings of $US92 076.The most frequent interventions were therapeuticconsultations (1062 interventions), followed by 1003dosage adjustments for renal function, and 678pharmacokinetic consultations. Dr Nesbit andcolleagues estimate that interventions under the CSPprogramme resulted in a cost avoidance of $US488 436from avoided adverse drug events (ADEs).* They say thatthe CSP programme cost $US187 852 in 12 months,**

representing a net value to the institution of $US392 660in ADE cost avoidance and drug acquisition cost savings.Dr Nesbit and colleagues based their economic findingson a literature-based cost estimate of $US5006/ADE. Ina sensitivity analysis they found that economic benefitscontinued to exceed costs until the estimated cost of anADE dropped to ≤ $US981.* Cost avoidance was calculated for each intervention by multiplyingthe probability of an ADE in the absence of an intervention by theestimated cost of an ADE.** cost of equipment plus practitioner salaries and benefits

Nesbit TW, et al. Implementation and pharmacoeconomic analysis of a clinicalstaff pharmacist practice model. American Journal of Health-System Pharmacy 58:784-790, 1 May 2001 800861242