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Clinical Anesthesia Part II JUNYI LI, MD [email protected] April 2, 2009

Clinical Anesthesia Part II JUNYI LI, MD [email protected] April 2, 2009

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Page 1: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Clinical Anesthesia

Part II

JUNYI LI, MD

[email protected]

April 2, 2009

Page 2: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Practice of anesthesiology

• Practice of anesthesiology is the practice medicine

• Preoperative evaluation

• Intraoperative management

• Postoperative care

• Anesthesiology is perioperative medicine

Page 3: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Practice of anesthesiology• Preoperative evaluation and patient preparation• Intraoperative management - General anesthesia Inhalation anesthesia Total IV anesthesia - Regional anesthesia & pain management Spinal, epidural & caudal blocks Peripheral never blocks Pain management (acute and chronic pain)• Postanesthesia care (PACU management)• Anesthesia complication & management• Case study

Page 4: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Preoperative anesthetic evaluation

• History 1. Current problem 2. Other known problem 3. Medication history: allergies, drug intolerances, present therapy, alcohol, tobacco 4. Previous anesthetics, operations 5. Family history of anesthesia 6. Review of organ systems 7. Last oral intake• Physical examination: VS, airway, CV, lung, neuro• Lab evaluation, chest X-ray, ECG• ASA classification

Page 5: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Physical status classification

• Class I: A normal healthy patients• Class II: A patient with mild systemic disease (no functional limitation)• Class III: A patient with severe systemic disease (some• functional limitation)• Class IV: A patient with severe systemic disease that is a constant threat to life (functionality incapacitated)• Class V: A moribund patient who is not expected to survive without the operation• Class VI: A brain-dead patient whose organs are being removed for donor purposes• Class E: Emergent procedure

Page 6: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Anesthetic planPremed Type of Intraoperative Postoperativeanesthesia management managementGeneral Monitoring Pain control Airway management Positioning Intensive care Induction Fluid management postop ventilation Maintenance Special techniques Hemodynanic monit Muscle relaxation

Regional Technique Agents

Monitored anesthesia care Supplement oxygen Sedation

Page 7: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Preoperative management

• Diabetes: hyperglycemia or hypoglycemia• Hypertension• Renal failure: HD patients – potassium level • Asthmatic patients• Chronic steroid use• Pregnant test• Preop medication: Sedation-benzodiazepine Aspiration precaution-H2 blockers, metoclopramide Antibiotics

Page 8: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

NPO status

• NPO, Nil Per Os, means nothing by mouth

• Solid food: 8 hrs before induction

• Liquid: 4 hrs before induction

• Clear water: 2 hrs before induction

• Pediatrics: stop breast milk feeding 4 hrs

before induction

Page 9: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

General Anesthesia

• Monitor• Preoxygenation• Induction ( including RSI & cricoid pressure)• Muscle relaxants• Mask ventilation• Intubation & ETT position comfirmation• Maintenance• Emergence

Page 10: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Airway examMallampati classification Class I:

uvula, faucial pillars, soft palate visible

Class II: faucial pillars, soft pillars visible

Class III: soft and hard palate visible

Class IV: hard palate visible

Page 11: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Sniffing position

Page 12: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Mask and airway tools

Page 13: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Mask ventilation and intubation

Page 14: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Oral and nasal airway

Page 15: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Intubation

Page 16: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Intubation

Page 17: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Laryngeal view

Page 18: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Laryngeal view scoring system

Page 19: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Difficult airway

Page 20: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Fiberoptic scope intubation

Page 21: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Trachea view Carina view

Page 22: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Glidescope

Page 23: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Fast track LMA

Page 24: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

LMA

Page 25: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Difficult Airway Algorithm

Page 26: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Induction agents

• Opioids – fentanyl

• Propofol, Thiopental and Etomidate

• Muscle relaxants:

Depolarizing

Nondepolarizing

Page 27: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Induction

• IV induction

• Inhalation induction

• Rapid sequence induction

Page 28: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

General Anesthesia

• Reversible loss of consciousness

• Analgesia

• Amnesia

• Some degree of muscle relaxation

Page 29: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Intraoperative management

• Maintenance

Inhalation agents: N2O, Sevo, Deso, Iso

Total IV agents: Propofol

Opioids: Fentanyl, Morphine

Muscle relaxants

Balance anesthesia

Page 30: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Intraoperative management

• Monitoring• Position – supine, lateral, prone, sitting, Litho• Fluid management - Crystalloid vs colloid - NPO fluid replacement: 1st 10kg weight- 4ml/kg/hr, 2nd 10kg weight-2ml/kg/hr and 1ml/kg/hr thereafter - Intraoperative fluid replacement: minor procedures 1-3ml/kg/hr, major procedures 4- 6ml/kg/hr, major abdominal procedures 7-10/kg/ml

Page 31: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Intraoperative managementEmergence

• Turn off the agent (inhalation or IV agents)

• Reverse the muscle relaxants

• Return to spontaneous ventilation with adequate ventilation and oxygenation

• Suction upper airway

• Wait for pts to wake up and follow command

• Hemodynamically stable

Page 32: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Postoperative management

• Post-anesthesia care unit (PACU) - Oxygen supplement

- Pain control

- Nausea and vomiting

- Hypertension and hypotension

- Agitation

• Surgical intensive care unit (SICU) - Mechanical ventilation

- Hemodynamic monitoring

Page 33: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

General Anesthesia Complication and Management

• Respiratory complication - Aspiration – airway obstruction and pneumonia - Bronchospasm - Atelectasis - Hypoventilation

• Cardiovascular complication - Hypertension and hypotension - Arrhythmia - Myocardial ischemia and infarction - Cardiac arrest

Page 34: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

General AnesthesiaComplication and Management

• Neurological complication - Slow wake-up

- Stroke

• Malignant hyperthermia

Page 35: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Regional Anesthesia

• No absolute indication for spinal or epidural anesthesia

• May improve outcome in selected situations• Blunt stress response to surgical stimulation• Decrease intraoperative blood loss• Lower the incidence of postoperative

thromboembolic events• Decrease M&M in high risk patients• Extend analgesia into postoperative period

Page 36: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Posterior and lateral view of spinal column

Spinal cord terminates

Page 37: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Human sensory dermatomes

Page 38: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009
Page 39: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Spinal anesthesia

• Patient position• Approachs: Midline & Paramedian• Technique• Monitoring during spinal anesthesia• Single dose spinal anesthesia• Continuous spinal anesthesia• Complications• Contraindications• Common local anesthetics for spinal anesthesia Lidocaine, Bupivacaine, Tetracaine, Ropivacaine

Page 40: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Physiology of Spinal Anesthesia

• LA blocks conduction of impulses along all with which it contacts

• Autonomic and pain fibers block - early

• Motor fibers block - late

Page 41: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Position

• Sitting position Sit straight first Chin on chest Arms resting on knees Footstool/table to support feet

Back curving like banana or shrimp • Lateral position Shoulders perpendicular to bed Positioned with hips on edge of bed Knee chest position and back curving

Page 42: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Approach

• Median approach• Most common

• Needle or introducer is placed midline

• Perpendicular to spinous processes

• Slightly cephalad

• Paramedian approach• For pts who cannot adequately flex

• Needle placed laterally(1.5cm) and slightly caudad to center

• Needle aimed medially and slightly cephalad

Page 43: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Midline approach to subarachnoid space

Page 44: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Technique

• Anatomic landmark identified• Superior iliac crests at L4 level• Spine is palpated• A sterile field estabolished• Skin wheel with LA• Introducer inserted and spinal needle passed• CSF presence• LA injection

Page 45: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Procedure

Page 46: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Monitoring

• Respiration

• Heart rate

• Blood pressure

Page 47: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

LA & Concentration T10 level T4 level Duration Duration upper abd lower abd plain with epiBupivacaine 0.75% 12-14mg 12-18mg 90-120min 100-150min

Tetracaine 1% 10-12mg 10-16mg 90-120min 120-240min

Lidocaine 5% 50-75mg 75-100mg 60-75min 60-90min

Ropivacaine 02-1% 12-16mg 16-18mg 90-120min 90-120min

Common local anesthetics

Page 48: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Factors affecting spread of LA solution

• Baricity of LA solution

• Position of patient

• Concentration volume injected

• Level of injection

• Speed of injection

Page 49: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Assessing the level of block

Page 50: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Complications

• Common complications Postdural punture headache

Transient radicular syndrome

Backache

Hypotension

Itching

Page 51: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Complications

• Less common complications Cauda equina syndrome Total spinal Urinary retention Cardiac arrest Spinal/epidural hematoma Aseptic meningitis Bacterial meningitis Cranial nerve palsies

Page 52: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Contraindications

• Relative contraindications Hypovolemia

Preexisting neurologic disorders

Chronic back pain

Localized infection peripheral to regional site

Patients taking ASA, NSAID, dipyridamole

Page 53: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Contraindications

• Absolute contraindications Patient refusal

Infection at puncture site

Generalized sepsis

Severe coagulation abnormalities

Raised ICP

Page 54: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Anesthesia• Position• Approach: midline & paramedian• Location: cervical, thoracic, lumbar• Technique• Monitoring• Single dose - pain management• Continuous epidural - anesthesia & analgesia• Complication• Contraindication• Common LA for epidural anesthesia & analgesia Bupivacaine and ropivacaine

Page 55: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Approach

Page 56: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Anesthesia Kit

Page 57: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Loss of resistance technique

Page 58: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Catheter Placement

Page 59: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Catheter Placement

Page 60: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Catheter placement

Page 61: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Epidural Catheter Placement

Page 62: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Complications• Similar to spinal anesthesia

• Wet tap – postpuncture headache

• Total spinal anesthesia – apnea, hypotension, bradycardia

Page 63: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Common LA for Epidural Anesthesia• Bupivacaine: 0.125-0.25% for analgesia

0.5% for anesthesia

• Ropivacaine: 0.2% for analgesia

0.5-1% for anethesia

• Lidocaine: 2% for anesthesia

Page 64: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Caudal Anesthesia

• Common regional technique in pediatric pts

• Caudal space is sacral portion of epidural space

• Needle penetration of sacrococcygeal ligament from sacral hiatus

• Caudal anesthesia technique is difficult or impossible due to calcification of sacrococcygeal ligament

Page 65: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Caudal Technique

Page 66: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Caudal Anesthesia

Page 67: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Peripheral Nerve Block

• Injection of LA near the nerves to block sensation and motor function

• Can be used as primary and sole anesthetic technique for selective surgery

• Can be used for postop pain control

Page 68: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Common Nerve Block

• Brachial plexus block - Interscalene approach

- Axillary approach

- Infroclavicular approach

• Intravenous regional anesthesia (Bier block)• Lumbar plexus block - Femoral block

• Sacral plexus block - Sciatic nerve block

Page 69: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Anatomy of Brachial Plexus

Page 70: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Brachial Plexus Block-Interscalene Approach

Page 71: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Lumbar and Sacral Plexus Distribution

Page 72: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Femoral and Sciatic Nerve block

Page 73: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Peripheral Nerve Block

• Complications: - Intravascular injection and toxicity

- Chronic paresthesias and nerve damage

- Respiratory failure due to phrenic nerve block

- Others: infection, bleeding, allergic reaction

- The greatest immediate risk is systemic toxicity

from inadvertent intravascular injection

Page 74: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Local Anesthetic Toxicity

Page 75: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Peripheral Nerve Block

• Contraindications: - Uncooperative patient

- Coagulopathy

- Local skin infection

- Peripheral neuropathy

- Local anesthetic toxicity

Page 76: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Management

• Most common symptom that brings patients to see a physician

• Pain is “an pleasant sensory and emotional experience associated with actual or potential tissue damage” (IASP)

• Component of anesthesia practice outside OR • “Nociception” (latin for harm or injury) is

used to describe the neural response only to traumatic or noxious stimuli

Page 77: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Management• Classification: Persistent time: acute and chronic pain

Pathophysiology: nociceptive and neuropathic pain

Etiology: postoperative, cancer pain

Affected area: headache, low back pain

Presentation: local, radiate, diffuse

Characteristic: burning,sting,blunt,distended,angina

Page 78: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Evaluation

(VRS)

Page 79: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009
Page 80: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Management

• Medicine for Acute pain: NSAIDS: Ibuprofen, Ketorolac, Naproxen

Opioids: Morphine, Fentanyl, Meperidine,

Hydromorphone

Local anesthetics: Lidocaine, Bupivacaine,

Ropivacaine

Page 81: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Management

• Administration route of pain medicine: - Oral - opioids, NSAIDs

- IV - single dose IV push or PCA(opioids, NSAIDs)

- IM - injection (opioids, NSAIDs)

- Local infiltration with LA

- Peripheral nerve block - intercostal, intrapleural

- Epidural - continuous or PCA with opioids, LA

- Intraspinal route with opioids

Page 82: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Pain Management - Chronic Pain

• Psychological and behavioral factors play a major role in chronic pain

• Psychology, neurosurgery consultation• Antidepression • Treatment of insomnia• Muscle relaxant • Oral NSAIDs and/or opioids• Neural blockade - somatic, sympathetic blocks• Radiofrequency ablation & cryoneurolysis• Spinal cord stimulation• Intraspinal pump for opioids and/or NSAIDs• Physical therapy: acupuncture

Page 83: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• 73 years old male presents for 6 cm AAA repair

• PMH: CAD, HTN, DM

• PSH: CABG, appendectomy

• Social Hx: smoke 1ppd for 50 years

• Current Med: Nitro patch, ASA, lisinopril, clonidine, glucophage

Page 84: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Preop evaluation:

- Current medical problems: CAD, HTN, DM,

long term smoke

- Past anesthesia history

- Preop test: ECG, CXR, cardiac function,

pulmonary function

- Preop lab: CBC, Chemistry, coagulation

Page 85: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Preop evaluation:

- Airway exam

- NPO

- Home med on the day of operation

- Blood glucose on the day of operation

- Premedication

- Blood products

Page 86: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Intraoperative management:

- Monitor:

Noninvasive: ECG, pulse O2 saturation, BP

Invasive: A-line, CVP, PAC

Urine output

- Induction and intubation

- Fluid management

Page 87: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Intraoperative management: - Aortic clamp increases afterload, significantly increases BP, may cause myocardia ischemia and heart failure, vasodilator may needed - Kidney protection: furosemide, mannitol - Aortic clamp release decreases afterload, significantly decreases BP, vasoconstrictor, calcium usually are used

Page 88: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Postoperative care:

- Postop ventilation:

Ventilator setting

Weaning from ventilator

- Hemodynamic monitor

- Lab: H/H, electrolytes, coagulation

Page 89: Clinical Anesthesia Part II JUNYI LI, MD lijunyiutmb@yahoo.com April 2, 2009

Case Study

• Complication:

- Bleeding: intra & postoperative

surgical & nonsurgical

- Cardiac complication

- Respiratory failure

- Renal insufficency