Citric acid cycle

Slide number: 1

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Once again a substrateis oxidized and NAD+ is reduced to NADH.

5.

Twice over, substrates are oxidized, NAD+ is reduced to NADH, and CO2 is released.

2.

ADP becomes ATP as a high-energy phosphate is removed from a substrate.

3.

Again a substrate is oxidized, but thistime FAD is reduced to FADH2.

4.

Acetyl–CoA

citrateC6

ketoglutarateC5

succinateC4

fumarateC4

oxaloacetateC4

CoA

NADH

NADH

NADH

FADH2

ATP

CO2

NAD+

NAD+

NAD+

FAD

CO2

Citric acid cycle

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Citric acid cycle

Slide number: 2

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Acetyl–CoA

citrateC6

oxaloacetateC4

CoA

Citric acid cycle

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Citric acid cycle

Slide number: 3

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Twice over, substrates are oxidized, NAD+ is reduced to NADH, and CO2 is released.

2.

Acetyl–CoA

citrateC6

ketoglutarateC5

oxaloacetateC4

CoA

NADH

NAD+

CO2

Citric acid cycle

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Citric acid cycle

Slide number: 4

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Twice over, substrates are oxidized, NAD+ is reduced to NADH, and CO2 is released.

2.

ADP becomes ATP as a high-energy phosphate is removed from a substrate.

3.

Acetyl–CoA

citrateC6

ketoglutarateC5

succinateC4

oxaloacetateC4

CoA

NADH

NADH

ATP

CO2

NAD+

NAD+

CO2

Citric acid cycle

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Citric acid cycle

Slide number: 5

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

Twice over, substrates are oxidized, NAD+ is reduced to NADH, and CO2 is released.

2.

ADP becomes ATP as a high-energy phosphate is removed from a substrate.

3.

Again a substrate is oxidized, but thistime FAD is reduced to FADH2.

4.

Acetyl–CoA

citrateC6

ketoglutarateC5

succinateC4

fumarateC4

oxaloacetateC4

CoA

NADH

NADH

FADH2

ATP

CO2

NAD+

NAD+

FAD

CO2

Citric acid cycle

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Citric acid cycle

Slide number: 6

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

The cycle begins when anacetyl group carried by CoA combines with a C4 molecule to form citrate.

1.

Once again a substrateis oxidized and NAD+ is reduced to NADH.

5.

Twice over, substrates are oxidized, NAD+ is reduced to NADH, and CO2 is released.

2.

ADP becomes ATP as a high-energy phosphate is removed from a substrate.

3.

Again a substrate is oxidized, but thistime FAD is reduced to FADH2.

4.

Acetyl–CoA

citrateC6

ketoglutarateC5

succinateC4

fumarateC4

oxaloacetateC4

CoA

NADH

NADH

NADH

FADH2

ATP

CO2

NAD+

NAD+

NAD+

FAD

CO2

Citric acid cycle