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Kks 1 Cipla Ltd Buy Below Rs.700/- only and hold at least 12 to 18 months months 14 th Apr, 2015 Industry Overview The market size of the global pharmaceutical industry is estimated to reach US$ 1.2 trillion by 2017 growing at a Compound Annual Growth Rate (CAGR) of 3-6% and the emerging markets are likely to be the key growth drivers. Several factors like economic growth, demographic changes, transition in community health and policy responses and focus on healthcare funding are expected to lead to double-digit growth in the pharmerging markets. On the other hand, economic and healthcare austerity measures and the savings realized from the growing availability of generic drugs, following their patent expiry, may see developed markets record low single-digit growth GLOBAL GENERICS A shift of the global spending mix towards generic over the next five years has been forecasted, a move primarily driven by the pharmerging markets, despite branded drugs continuing to form almost two-thirds of global spending in the developed markets. It is estimated that the generic spending on medicines will grow from US$ 261 billion in 2012 to US$ 421-432 billion by 2017 globally. Global generic spending is likely to reach 36% of total spending by 2017, as against 27% in 2012. INDIAN PHARMACEUTICAL SECTOR The Indian pharmaceutical market is estimated to reach US$ 22-32 billion by 2017 compared to US$ 14 billion in 2012, establishing India as the 11th largest market by 2017, compared to its 13th position in 2012.

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  • Kks

    1

    Cipla Ltd

    Buy Below Rs.700/- only and hold at least 12 to 18 months months 14th Apr, 2015

    Industry Overview The market size of the global pharmaceutical industry is estimated to reach US$ 1.2

    trillion by 2017 growing at a Compound Annual Growth Rate (CAGR) of 3-6% and

    the emerging markets are likely to be the key growth drivers.

    Several factors like economic growth, demographic changes, transition in

    community health and policy responses and focus on healthcare funding are

    expected to lead to double-digit growth in the pharmerging markets. On the other

    hand, economic and healthcare austerity measures and the savings realized from the

    growing availability of generic drugs, following their patent expiry, may see

    developed markets record low single-digit growth

    GLOBAL GENERICS

    A shift of the global spending mix towards generic over the next five years has been

    forecasted, a move primarily driven by the pharmerging markets, despite branded

    drugs continuing to form almost two-thirds of global spending in the developed

    markets.

    It is estimated that the generic spending on medicines will grow from US$ 261

    billion in 2012 to US$ 421-432 billion by 2017 globally. Global generic spending is

    likely to reach 36% of total spending by 2017, as against 27% in 2012.

    INDIAN PHARMACEUTICAL SECTOR

    The Indian pharmaceutical market is estimated to reach US$ 22-32 billion by 2017

    compared to US$ 14 billion in 2012, establishing India as the 11th largest market by

    2017, compared to its 13th position in 2012.

  • Kks

    2

    Company overview

    Cipla is incorporated by Khwaja Abdul Hamied in 1935; he set up The Chemical,

    Industrial & Pharmaceutical Laboratories, which came to be popularly known as

    Cipla. On August 17, 1935, Cipla was registered as a public limited company with an

    authorized capital of Rs 6 lakhs.

    Cipla has over 34 state-of-the-art manufacturing units which have been approved by

    various Ministries of Health and Regulatory Authorities like USFDA, WHO, MCC-

    South Africa, MHRAUK, TGA-Australia among others. The company presence in

    over 150 countries, portfolio includes 1500 products in various therapeutic categories

    with one quality standard globally, Ciplas product portfolio comprises of Active

    Pharmaceutical Ingredients (APIs), Formulations for Human and Animal Healthcare

    and OTC products. Cipla has the technological prowess of manufacturing products in

    most dosage forms across therapeutic categories, which offers the company a unique

    competitive advantage. The Companys R&D centre primarily focuses towards

    developing innovative products and drug delivery systems and has given the country

    and the world many Firsts. This includes the revolutionary HIV/AIDS cocktail for

    less than a Dollar a Day.

    As part of its international business, Cipla enters into strategic alliances and agency

    arrangements for product registration, development and distribution of its products.

    It also provides technological consultancy services for pharmaceutical projects in

    developed markets, particularly the U.S. and Europe. In addition, the company also

    maintains long-standing relationships with non-governmental organizations and

    institutions outside India. Cipla has earned a name for maintaining world-class

    quality across all its products and services. With the dedication of its 20,000

    employees, Cipla continues to support, improve and save millions of lives with its

    high-quality drugs and innovative devices and is focused towards its commitment

    that None shall be denied.

  • Kks

    3

    Others overview Cipla (EU) Limited, U.K., a wholly owned subsidiary of the Cipla Ltd, has

    entered into a joint venture (JV) agreement with Company's existing business

    partners in Morocco - Societe Marocaine De Cooperation Pharmaceutique &

    the Pharmaceutical Institute (PHI).

    The Company has signed a definitive agreement to acquire 60% stake of Jay

    Precision Pharmaceuticals Private Limited Mumbai, from the existing

    shareholders, for a cash consideration of Rs. 960.00 mn.

    Cipla Ltd has reporte d that Meditab Holdings Limited, Mauritius, a

    wholly owned subsidiary of the Company, has entered into a definitive

    agreement to sell its entire 48.22% equity interest in Jiangsu Cdymax

    Pharmaceuticals Co. Ltd., China.

    Cipla Ltd has reported that a binding term sheet has been entered into with

    the Company's existing partner, Biopharm SPA, for establishing a joint

    venture ("JV") company in Algeria. The JV Company will manufacture and

    market respiratory products facilitating Ciplas front-end presence in Algeria.

    The company has been awarded USD 188.95 million of Global Fund ARV

    Tender. Cipla has been selected as a Panel Supplier for a Supplier Partnership

    Agreement. The contract is effective from the 1st of January 2015 and will run

    for a period of three years.

    Cipla Europe NV (Cipla) has signed a distribution agreement with Serum

    Institute of India Ltd.(SII).

    Medicines for Malaria Venture (MMV) signs collobaration agreements with

    two Indian pharmaceuticals companies, Cipla Ltd and Strides Arcolab Limited

    for the development of rectal Artesunate for pre-referral treatment of children

    with severe malaria.

    Stempeutics Research, a group company of Manipal Education and Medical

    Group and a Joint Venture with Cipla Group, reported that the United States

    Patent and Trademarks Office (USPTO) granted a US process patent for its

    novel stem-cell based drug Stempeucel.

  • Kks

    4

    Crisp facts

    Ranked thirteenth in terms of value in the global pharmaceutical industry in

    2012

    Fourth largest among the pharmerging markets in terms of market size in

    2012

    Projected to grow at a CAGR of 11-14% during 2013-2017

    One of the key exporters to the US and other markets - the highest number of

    US FDA approved manufacturing facilities outside USA.

    Indian pharmaceutical companies received over 150 ANDA approvals from

    US FDA during 2013, accounting for approximately 38% of the total

    approvals.

    The Indian pharmaceutical industry received foreign direct investments (FDI) worth

    around US$ 11.95 billion during April, 2000 to September, 2013.

    Exports

    The pharmaceutical exports from India during 2012-13 stood at US$ 14.6 billion,

    witnessing an increase of US$ 1.4 billion from 2011-12. Indian pharmaceutical sector

    exports are likely to reach US$ 25 billion by 2016.

    Demand drivers

    Rising spend on healthcare

    Total annual healthcare spending is expected to more than double to US$

    201.4 billion, growing at an average annual rate of 15.8% during 2012-2017.

    Healthcare spending is estimated to be around 0.5% of GDP in 2013.

    Growing health insurance coverage

    The Indian government plans to bring 80% of Indias population under health

    insurance cover under its Health Insurance Vision 2020. This will lead to

    higher volumes for the pharmaceuticals industry.

  • Kks

    5

    Growing incidence of chronic diseases

    Chronic therapies have grown at a faster pace than that of traditional acute

    therapies over the past four years. Their contribution in the Indian

    pharmaceutical market escalated from 27% in 2010 to 30% in 2013. Lifestyle

    changes, rapid urbanization and increasing affluence are factors which are

    expected to drive it further.

    Rapid urbanisation

    An increase in urban population from 31% to 40% or more by 2030 will see

    better accessibility, with which will come with rapid urbanisation and the

    growth of the pharmaceutical industry.

    Others Drivers Building strong foundation to grow faster

    Cipla is in the process of business transformation, which is affecting the short-

    term performances, but will lead to a solid foundation for a long-term growth

    and profitability. During the last 12 months, the company has entered into

    several collaborative and joint venture deals (17 deals during the year) to

    expand its presence in key markets and sharpen its focus on niche segments.

    Although, most of these deals are focused on Europe and emerging markets,

    the market is buzzing about the possible inorganic initiatives in the US

    market.

    Expect margin profile to improve

    Most of the recent deals are focused on sharpening its focus on niche

    segments, where competition is low and margins are better. A selective

    business approach and focus on technology-intensive products profile are set

    to strengthen its margin profile over a period of time. I expect over 350-BPS

    improvement in OPM over FY2015-17.

  • Kks

    6

    Tie-ups and agreements

    During the last 12 months, the company entered into 17 collaborations, tie-

    ups, joint ventures, in-licencing and out-licencing deals, most of such deals are

    small in size but focused on niche segments.

    Tender-based business to see better traction

    The deals sealed during the year include manufacturing and supply

    agreements with Global Fund for AIDS, Tuberculosis and Malaria tenders

    ($189-million worth tenders to be executed over the next three years),

    Medicines for Malaria Venture (MMV) for the development of rectal

    artesunate for pre-referral treatment of children with severe malaria and tie-

    up with Medicine Patent Pool (MPP) to manufacture generic HIV medicines,

    atazanavir (ATV) and dolutegravir (DTG) and market them in developing

    countries. These deals are set to give higher exposure to tender-based

    institutional business over a period of time and also help improve the

    operating margins.

    Expanding manufacturing base for smaller markets

    The company entered into multiple joint-venture agreements to broad-base

    the manufacturing infrastructure and tap the growth potential in smaller

    markets. These deals include setting up a joint venture in Algeria (with

    Biopharma SPA with an initial investment of $6 million) and Morocco (with

    Cooper Pharma and The Pharmaceutical Institute).

    In-licencing deals to enrich product basket

    Cipla Medpro (South African arm of Cipla) entered into in-licencing deals

    with Teva Pharmaceutical Industries (Teva) to market a number of generic

    products in the South African market. Besides, it also entered into inlicencing

    deals with Gilead Sciences Inc to manufacture and market Sofosbuvir and

    Ledipasvir in 91 countries including India and South Africa under Ciplas own

    brand name. It also entered into in-licencing agreements with BioQuiddity Inc

    to market an anesthetic product, OneDose ReadyfusOR, in Europe, with MSD

    to co-market raltegravir 400mg tablet in India and with Hetero to launch a

    biosimilar of the drug Darbepoetin Alfa under the brand name Actorise in

    India.

  • Kks

    7

    R&D collaboration and out-licencing deals

    Cipla has collaborated with US-based Chase Pharmaceuticals (Chase Pharma)

    to invest in its novel product, which is undergoing clinical trials. Chase

    Pharma is focused on developing novel approaches to improve treatment of

    Alzheimers disease. Cipla will invest $21 million in two phases to support the

    programme and will also collaborate to develop the drug and market it in

    India and South Africa. Besides, it also entered in an agreement with Salix

    Pharmaceuticals in USA to provide exclusive rights under certain patent

    applications in the Rifaximin Complexes patent family controlled by Cipla in

    lieu of royalty, upfront and milestone-based payments.

    Industry concerns.

    Regulatory challenges

    The Indian pharmaceutical market has its own set of regulatory challenges in the

    form of:

    Government-mandated price controls

    Delay in new product approvals

    Delay in clinical trial approvals

    Uncertainties over FDI policy

    These concerns act as a deterrent to the growth of the industry.

    Manufacturing quality

    India is attracting greater scrutiny from the US FDA in relation to cGMP compliance,

    owing to the fact that it is the largest drugs supplier to the US. Indian companies will

    have to conform to standards at par with the global benchmarks. This will involve

    continuous improvement in systems and processes and training of the workforce to

    ensure compliance to such standards.

  • Kks

    8

    Recent deals, tie-ups and collaboration by Cipla

    Date Target/

    Collaborator

    company

    Stake/

    share

    Country

    covered

    Investments/

    Financial

    terms

    Type of

    collaboration

    Objective/ Rationale

    13-Feb-15 Global Fund

    ARV Tender

    NA 140

    emerging

    countries

    Not disclosed Develop and

    supply

    agreement

    Cipla is among those

    selected as a Panel

    Supplier for a Supplier

    Partnership Agreement;

    the contract is effective

    from

    the January 1, 2015 and

    will run for a

    period of three years; the

    supplies will

    begin from Q4FY2015

    12-Feb-15 Biopharma

    SPA

    40% Algeria $6 million JV The new company is

    expected to make an

    investment of up to $15

    million to build a

    factory

    12-Feb-15 Jay Precision

    Pharma

    60% India $15 million Strategic

    investments

    JPP is an existing supplier

    of respiratory devices to

    Cipla and has a

    manufacturing

    facility at Vasai,

    Maharashtra; It has an

    annual turnover of over

    Rs30 crore. Cipla

    will use it as a platform to

    develop nextgeneration

    respiratory devices

    9-Feb-15 Cooper

    Pharma and

    The

    Pharmaceuti

    cal Institute(

    PHI)

    60% Morocco $15 million JV The JV will enable Cipla

    to establish a front-end

    presence in Moroccos

    pharmaceutical market;

    the JV shall invest in

    setting up a

    manufacturing

    facility in Morocco to

    produce respiratory

    and neurology products

    27-Nov-14 Medicines for

    Malaria

    Venture

    NA Developin

    g

    countries

    Not disclosed Develop and

    supply

    agreement

    For the development of

    rectal artesunate for pre-

    referral treatment of

    children with

  • Kks

    9

    severe malaria; the goal

    is to achieve

    WHO-prequalification of

    a rectal

    artesunate product by

    2016

    20-Nov-14 Serum

    Institute of

    India

    NA Europe Not disclosed Commercial

    collaboration

    SII will develop and

    manufacture paediatric

    vaccines, Cipla will seek

    European Medicines

    Agencys approval and

    market the products in

    Europe

    8-Oct-14 Teva Pharma NA South

    Africa

    Not disclosed In-licencing

    deal

    The collaboration is a

    sales and

    distribution arrangement

    whereby Cipla

    Medpro will exclusively

    market Tevas

    broad pharmaceutical

    product portfolio in

    South Africa; the

    products will cover

    oncology, central nervous

    system, womens

    health, cardiovascular,

    ophthalmology and

    other specialty segments

    25-Sep-14 Surgipharm

    Limited

    NA Kenya Not disclosed Commercial

    collaboration

    The products will be

    brought to Kenyan

    patients in partnership

    with Surgipharm,

    which will be a

    distribution partner

    25-Sep-14 Medicines

    Patent Pool

    NA 112

    developin

    g

    countries

    Not disclosed Sub-licencing MPP announced six new

    sub-licences with generic

    companies including

    Cipla to allow

    generic manufacture of

    tenofovir

    alafenamide for HIV

    treatments in 112

    developing countries

    18-Sep-14 Salix

    Pharmaceuti

    cals

    NA USA Not disclosed out-licencing

    deals

    Cipla has granted Salix

    Pharmaceuticals

    exclusive rights under

    certain patent

    applications in the

  • Kks

    10

    Rifaximin Complexes

    patent family controlled

    by Cipla

    15-Sep-14 Gilead

    Sciences, inc

    NA Emerging

    markets

    Not disclosed In-licencing

    deal

    As per the agreement,

    Cipla will be allowed to

    manufacture and market

    Sofosbuvir and Ledipasvir

    in 91 countries

    including its home

    markets India, South

    Africa and Egypt, which

    has a high

    incidence of Hepatitis C,

    under Ciplas

    own brand names; Cipla

    has the option of

    receiving a technology

    transfer of the

    manufacturing process

    from Gilead

    Sciences Inc

    8-Sep-14 S&D Pharma NA Czech

    Republic

    and

    Slovakia

    Not disclosed Commercial

    collaboration

    Under the collaboration,

    Cipla will be driving its

    respiratory product

    portfolio in

    both Czech Republic and

    Slovakia through

    Cipla owned sales force

    team, managed by

    Cipla commercial head;

    S&D Pharma will

    physically distribute all

    products, including

    respiratory products, and

    this portfolio will

    increase over the next

    few years

    31-Jul-14 BioQuiddity

    Inc

    NA Europe Not disclosed In-licencing

    deal

    To market an anesthetic

    product, OneDose

    ReadyfusOR, in Europe

    17-Jul-14 Medicines

    Patent Pool

    NA - Not disclosed Sub-licencing To manufacture of

    generic HIV medicines,

    ATV and DTG and

    market in developing

    countries

    19-Jun-14 Hetero NA India Not disclosed In-licencing

    deal

    To launch a biosimilar of

    the drug

    Darbepoetin Alfa under

  • Kks

    11

    the brand name

    Actorise

    12-May-14 Chase

    Pharmaceuti

    cals

    NA US $21 million

    in two phases

    R&D

    collaboration

    and

    investments

    Chase is focused on

    developing novel

    approaches to improve

    treatments for

    Alzheimers disease;

    Cipla will also

    collaborate to develop the

    drug and

    market it in India and

    South Africa

    20-Feb-14 MSD NA India Not disclosed In-licencing

    deal

    Co-market MSDs

    raltegravir 400mg tablet,

    for the Indian market

    Finance at a Glance

    INCOME DATA Year Ending Mar-10 Mar-11 Mar-12 Mar-13 Mar-14

    Net Sales Rs m 53,595 63,239 70,207 82,793 1,01,004

    Other income Rs m 3,535 917 1,395 2,221 2,654

    Total revenues Rs m 57,130 64,156 71,602 85,015 1,03,658

    Gross profit Rs m 10,677 13,916 16,618 21,979 21,331

    Depreciation Rs m 1,671 2,733 3,122 3,305 3,726

    Interest Rs m 230 251 383 339 1,457

    Profit before tax Rs m 12,311 11,849 14,508 20,556 18,800

    Minority Interest Rs m 0 0 0 0 -159

    Prior Period Items Rs m 0 -1 0 -62 -123

    Extraordinary Inc (Exp) Rs m 950 0 0 398 0

    Tax Rs m 2,435 1,952 3,065 5,443 4,634

    Profit after tax Rs m 10,826 9,896 11,442 15,449 13,884

    Gross profit margin % 19.9 22 23.7 26.5 21.1

    Effective tax rate % 19.8 16.5 21.1 26.5 24.6

    Net profit margin % 20.2 15.6 16.3 18.7 13.7

  • Kks

    12

    BALANCE SHEET DATA Year Ending Mar-10 Mar-11 Mar-12 Mar-13 Mar-14

    Current assets Rs m 43,673 44,431 50,568 67,840 56,514

    Current liabilities Rs m 12,143 16,985 14,132 22,776 25,636

    Net working cap to sales % 58.8 43.4 51.9 54.4 30.6

    Current ratio x 3.6 2.6 3.6 3 2.2

    Inventory Days Days 103 110 96 105 105

    Debtors Days Days 107 86 81 74 59

    Net fixed assets Rs m 26,954 33,795 35,867 39,878 44,452

    Share capital Rs m 1,606 1,606 1,606 1,606 1,606

    "Free" reserves Rs m 57,409 64,672 74,248 87,818 98,591

    Net worth Rs m 59,106 66,661 76,389 90,187 1,00,504

    Long term debt Rs m 38 179 33 6 3,179

    Total assets Rs m 73,091 85,967 93,498 1,16,588 1,34,032

    Interest coverage x 54.5 48.2 38.8 61.6 13.9

    Debt to equity ratio x 0 0 0 0 0

    Sales to assets ratio x 0.7 0.7 0.8 0.7 0.8

    Return on assets % 15.1 11.8 12.6 13.5 11.4

    Return on equity % 18.3 14.8 15 17.1 13.8

    Return on capital % 22.8 18.1 19.5 23.5 19.3

    Exports to sales % 54.1 53.2 52.6 53.5 49

    Imports to sales % 19.4 22 16.1 15.9 14.1

    Exports Rs m 29,006 33,615 36,920 44,262 49,480

    Imports Rs m 10,408 13,919 11,333 13,162 14,261

    Fx inflow Rs m 30,577 34,177 37,282 44,947 51,499

    Fx outflow Rs m 12,022 15,635 13,292 15,906 18,943

    Net fx Rs m 18,555 18,542 23,990 29,042 32,556

    CASH FLOW Year Ending Mar-10 Mar-11 Mar-12 Mar-13 Mar-14

    From Operations Rs m 10,430 10,251 17,128 13,977 15,627

    From Investments Rs m -5,628 -9,084 -9,651 -20,629 -12,499

    From Financial Activity Rs m -4,716 -828 -7,532 7,178 -2,656

    Net Cash flow Rs m 87 339 -55 526 472

  • Kks

    13

    EQUITY SHARE DATA Year Ending Mar-10 Mar-11 Mar-12 Mar-13 Mar-14

    Sales per share (Unadj.) Rs 66.7 78.8 87.4 103.1 125.8

    Earnings per share (Unadj.) Rs 13.5 12.3 14.3 19.2 17.3

    Diluted earnings per share Rs 13.5 12.3 14.3 19.2 17.3

    Cash flow per share (Unadj.) Rs 15.6 15.7 18.1 23.4 21.9

    Dividends per share (Unadj.) Rs 2 2.8 2 2 2

    Adj. dividends per share Rs 2 2.8 2 2 2

    Dividend yield % 0.7 0.8 0.6 0.5 0.5

    Book value / share (Unadj.) Rs 73.6 83 95.1 112.3 125.2

    Adj. book value per share Rs 73.6 83 95.1 112.3 125.2

    Shares outstanding m 802.99 802.92 802.92 802.92 802.92

    Price / Sales ratio x 4.3 4.2 3.6 3.6 3.2

    Avg P/E ratio x 21.3 27.1 22.2 19.1 23.5

    P/CF ratio x 18.4 21.2 17.4 15.8 18.6

    Price / Book Value ratio x 3.9 4 3.3 3.3 3.3

    Dividend payout % 14.8 22.7 14 10.4 11.6

    Avg Mkt Cap Rs m 2,30,057 2,67,774 2,54,124 2,95,475 3,26,829

    PEER GROUPS PEER GROUPS MARKET CAP EPS (TTM) P/E (X) P/BV(X) P/CF(X)

    Company Name (Rs.) Rs. in mn. (Rs.) Ratio Ratio Ratio

    Cipla Ltd 660.10 529967 14.70 44.80 5.28 29.60

    Lupin Ltd 1727.00 775786 53.60 32.20 11.12 36.40

    Sun Pharmaceuticals

    Industries Ltd

    942.50 1951965 28.80 32.70 26.35 45.50

    Dr. Reddy's

    Laboratories Ltd

    3516.00 599021 127.70 27.50 6.42 22.90

  • Kks

    14

    Conclusion

    Cipla Ltd laid foundations for the Indian pharmaceutical industry back in

    1935 with the vision to make India self-reliant in healthcare and is one of the

    largest exporters of pharmaceutical products from India and has a strong

    presence in over 150 countries.

    Cipla (EU) Limited, U.K., a wholly owned subsidiary of the Cipla Ltd, has

    entered into a joint venture (JV) agreement with Company's existing business

    partners in Morocco Societe Marocaine De Cooperation Pharmaceutique &

    the Pharmaceutical Institute (PHI).

    The Company has signed a definitive agreement to acquire 60% stake of Jay

    Precision Pharmaceuticals Private Limited Mumbai, from the existing

    shareholders, for a cash consideration of Rs. 960.00 mn.

    Cipla Ltd has reported that Meditab Holdings Limited, Mauritius, a wholly

    owned subsidiary of the Company, has entered into a definitive agreement to

    sell its entire 48.22% equity interest in Jiangsu Cdymax Pharmaceuticals Co.

    Ltd., China.

    Net Sales of the company is expected to grow at a CAGR of 9% over 2013 to

    2016E.

    Buy below Rs.700/- or more for short term target Rs.820/- to long term

    Rs.2,100/-