21
China Healthcare Health Care Health Care Industry Update Asia Japan North America Industry China Healthcare Date 17 January 2018 Deutsche Bank Markets Research Monthly data tracker: December 2017 Monthly data tracker: December 2017 Recent data suggest that 1) drug consumption was up 11.0% YoY in November vs. 12.4% in YTD10m17; 2) inpatient and outpatient traffic increased 7.3% and 3.0%, respectively, in YTD10m17; 3) government spending on healthcare dropped 16% YoY in November 2017 vs. 14% growth in YTD10m17; 4) vitamin C prices remained high; 5) 6-APA and 7-ACA prices were flat in December; 6) TCM raw material prices were mixed; and 7) corn prices remained the same at RMB1,690/ ton in December vs. November. Government spending, drug consumption, patient traffic and insurance Government spending on healthcare declined 16% YoY to RMB99bn in November 2017, while YTD10m17 growth was 14% vs. 10% YoY in 2016. Meanwhile, drug consumption grew 11.0% YoY in November 2017; YTD10m17 growth was 12.4% vs. 12.0% YoY in 2016 and vs. 14.2% YoY in 2015, respectively. Inpatient traffic continued to outpace outpatient flow, with 7.3% vs. 3.0% YoY growth in YTD10m17. In November, inflow and outflow of urban basic medical insurance increased 27% and 41% YoY, respectively. For commercial insurance, the inflow of healthcare insurance shot up 36% YoY in November 2017, and growth of healthcare insurance outflow accelerated to 32% YoY. On a YTD basis, inflow grew 5% and outflow climbed 29% YoY in YTD10m17. Vitamin C prices remained high; 6-APA and 7-ACA prices unchanged The ASP of domestic vitamin C edged up to RMB72.5/kg in December 2017, while exported vitamin C prices were stable at USD7.0/kg in November. Both prices of 6-APA and 7-ACA were flat in December 2017, recording RMB230/kg and RMB450/kg respectively. We remind investors that the main manufacturers resumed production of 7-ACA in September 2015 at a 16% price cut from RMB630/kg in June 2015. TCM raw material prices mixed Valuation and risks Our valuation is based on P/E or EV/EBITDA, depending on the sub-sector. In this report, we adjust TPs for Aier, CSPC and Topchoice, as specified in the Valuation and Risks section. Risks may vary by company and include raw material prices, new product launches and pipeline progress, price cuts, M&A, etc. In December 2017, the TCM raw material price index turned from its previous uptrend and decreased 1.32% MoM to 1,266. The ASP of honeysuckle was flat, while the price of indigowoad root further dropped 4% MoM in December 2017. Honeysuckle and indigowoad are the main ingredients in Shineway’s flagship product, Qing Kai Ling. The price of ophiopogon root remained unchanged in December, while ASP of radix ginseng fell 3% MoM. These are the main ingredients in Shen Mai. Jack Hu, Ph.D. Research Analyst +852-2203 6208 Megan Xu Research Associate +852-2203 5928 Key Changes Company Target Price Rating 1093.HK 19.10 to 20.30 - 300015.SZ 35.20 to 38.10 - 600763.SS 27.20 to 31.00 - Source: Deutsche Bank Top picks Sino Biopharmaceutical (1177.HK),HKD14.84 Buy Universal Medical (2666.HK),HKD7.38 Buy Jointown Pharmaceuticals (600998.SS),CNY17.96 Buy Source: Deutsche Bank Deutsche Bank AG/Hong Kong Deutsche Bank does and seeks to do business with companies covered in its research reports. Thus, investors should be aware that the firm may have a conflict of interest that could affect the objectivity of this report. Investors should consider this report as only a single factor in making their investment decision. DISCLOSURES AND ANALYST CERTIFICATIONS ARE LOCATED IN APPENDIX 1. MCI (P) 083/04/2017. THE CONTENT MAY NOT BE DISTRIBUTED IN THE PEOPLE ’ S REPUBLIC OF CHINA (“THE PRC”) (EXCEPT IN COMPLIANCE WITH THE APPLICABLE LAWS AND REGULATIONS OF PRC), EXCLUDING SPECIAL ADMINISTRATIVE REGIONS OF HONG KONG AND MACAU. Distributed on: 16/01/2018 16:57:10 GMT 7T2se3r0Ot6kwoPa

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Page 1: China Healthcare Industrypg.jrj.com.cn › acc › Res › CN_RES › INDUS › 2018 › 1 › 17 › 292fa220-8… · 17-01-2018  · Health Care Industry Update Asia Japan North

17 January 2018

Health Care

China Healthcare

Health CareHealth Care

Industry Update

AsiaJapanNorth America

Industry

China HealthcareDate17 January 2018

Deutsche BankMarkets Research

Monthly data tracker: December 2017

Monthly data tracker: December 2017Recent data suggest that 1) drug consumption was up 11.0% YoY in Novembervs. 12.4% in YTD10m17; 2) inpatient and outpatient traffic increased 7.3% and3.0%, respectively, in YTD10m17; 3) government spending on healthcare dropped16% YoY in November 2017 vs. 14% growth in YTD10m17; 4) vitamin C pricesremained high; 5) 6-APA and 7-ACA prices were flat in December; 6) TCM rawmaterial prices were mixed; and 7) corn prices remained the same at RMB1,690/ton in December vs. November.

Government spending, drug consumption, patient traffic and insuranceGovernment spending on healthcare declined 16% YoY to RMB99bn in November2017, while YTD10m17 growth was 14% vs. 10% YoY in 2016. Meanwhile,drug consumption grew 11.0% YoY in November 2017; YTD10m17 growth was12.4% vs. 12.0% YoY in 2016 and vs. 14.2% YoY in 2015, respectively. Inpatienttraffic continued to outpace outpatient flow, with 7.3% vs. 3.0% YoY growth inYTD10m17. In November, inflow and outflow of urban basic medical insuranceincreased 27% and 41% YoY, respectively. For commercial insurance, the inflowof healthcare insurance shot up 36% YoY in November 2017, and growth ofhealthcare insurance outflow accelerated to 32% YoY. On a YTD basis, inflowgrew 5% and outflow climbed 29% YoY in YTD10m17.

Vitamin C prices remained high; 6-APA and 7-ACA prices unchangedThe ASP of domestic vitamin C edged up to RMB72.5/kg in December 2017,while exported vitamin C prices were stable at USD7.0/kg in November. Bothprices of 6-APA and 7-ACA were flat in December 2017, recording RMB230/kgand RMB450/kg respectively. We remind investors that the main manufacturersresumed production of 7-ACA in September 2015 at a 16% price cut fromRMB630/kg in June 2015.

TCM raw material prices mixedValuation and risksOur valuation is based on P/E or EV/EBITDA,depending on the sub-sector. In this report,we adjust TPs for Aier, CSPC and Topchoice,as specified in the Valuation and Riskssection. Risks may vary by company andinclude raw material prices, new productlaunches and pipeline progress, price cuts,M&A, etc.

In December 2017, the TCM raw material price index turned from its previousuptrend and decreased 1.32% MoM to 1,266. The ASP of honeysuckle was flat,while the price of indigowoad root further dropped 4% MoM in December 2017.Honeysuckle and indigowoad are the main ingredients in Shineway’s flagshipproduct, Qing Kai Ling. The price of ophiopogon root remained unchangedin December, while ASP of radix ginseng fell 3% MoM. These are the mainingredients in Shen Mai.

Jack Hu, Ph.D.

Research Analyst

+852-2203 6208

Megan Xu

Research Associate

+852-2203 5928

Key ChangesCompany Target Price Rating

1093.HK 19.10 to 20.30 -

300015.SZ 35.20 to 38.10 -

600763.SS 27.20 to 31.00 -Source: Deutsche Bank

Top picks

Sino Biopharmaceutical(1177.HK),HKD14.84

Buy

Universal Medical (2666.HK),HKD7.38 Buy

Jointown Pharmaceuticals(600998.SS),CNY17.96

Buy

Source: Deutsche Bank

Deutsche Bank AG/Hong Kong

Deutsche Bank does and seeks to do business with companies covered in its research reports. Thus, investors should beaware that the firm may have a conflict of interest that could affect the objectivity of this report. Investors should considerthis report as only a single factor in making their investment decision. DISCLOSURES AND ANALYST CERTIFICATIONSARE LOCATED IN APPENDIX 1. MCI (P) 083/04/2017. THE CONTENT MAY NOT BE DISTRIBUTED IN THE PEOPLE ’ SREPUBLIC OF CHINA (“THE PRC”) (EXCEPT IN COMPLIANCE WITH THE APPLICABLE LAWS AND REGULATIONS OFPRC), EXCLUDING SPECIAL ADMINISTRATIVE REGIONS OF HONG KONG AND MACAU.

Distributed on: 16/01/2018 16:57:10 GMT

7T2se3r0Ot6kwoPa

Page 2: China Healthcare Industrypg.jrj.com.cn › acc › Res › CN_RES › INDUS › 2018 › 1 › 17 › 292fa220-8… · 17-01-2018  · Health Care Industry Update Asia Japan North

17 January 2018

Health Care

China Healthcare

Drug consumption growthpicked upDrug sales up 11.0% YoY in November 2017

The sales of traditional Chinese and Western medicine increased 11.0% YoYto RMB89bn in November 2017, vs. 11.5% YoY in November 2016. On aquarterly basis, retail drug consumption grew 14.6% YoY in 3Q17, compared with14.8%, 10.7%, 10.6%, 11.1% and 11.6% in 2Q17, 1Q17, 4Q16, 3Q16 and 2Q16,respectively.

For FY16, sales grew 12.0% vs. 14.2% in 2015 and 15.0% in 2014. We remindinvestors that drug consumption data correlate strongly with hospital drug salesdata.

Figure 1: YoY growth rate in total traditional Chinese and Western medicineconsumption revenue (May 2013 – November 2017)

0%

5%

10%

15%

20%

25%

YoY growth of drug consumption

Source: Deutsche Bank, NBS

Low- to mid-teen growth in drug consumption (mainly retail) appears to be thenew norm, consistent with feedback from company executives. For 2018, weremain constructive on the healthcare sector on the back of improving regulatoryframework, foreseeable NRDL benefit and rebound of regulatory approvals ofdomestic names.

Page 2 Deutsche Bank AG/Hong Kong

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17 January 2018

Health Care

China Healthcare

Inpatient and outpatientgrowthYTD Oct 2017, inpatient and outpatient up 7.3% and 3.0%,respectively

Demand for healthcare services and an infrastructure build-up drove growthin inpatient and outpatient volume and value from 2006 to 2010. The growthslowdown in 2010 can be attributed to the implementation of the new healthcarereforms and cost control over healthcare in China. From 2011 to YTD Oct 2017,growth of outpatient volume decelerated from 7.4% to 3.0%, and growth ofinpatient volume moderated from 7.9% to 7.3%.

Growth in average spending per hospital visit has been relatively stable since2011. The YoY growth rates have been maintained at between 6.3% and 7.8% foroutpatients and between 5.2% and 7.1% for inpatients.

Figure 2: Inpatient and outpatient volume growth ratesin China (2006 – YTD Oct 2017)

Figure 3: Inpatient and outpatient value (cost per visit)growth rates in China (2006 – 2015)

0%

5%

10%

15%

20%

25%

30%

Outpatients YoY Inpatients YoY

0%

2%

4%

6%

8%

10%

12%

2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Outpatient Inpatient

Source: Deutsche Bank, HNFPC Source: Deutsche Bank, HNFPC

Deutsche Bank AG/Hong Kong Page 3

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17 January 2018

Health Care

China Healthcare

Growth in governmenthealthcare spendingGovernment spending dropped 16% YoY in November2017 vs. 14% in YTD10m17

Total government spending on healthcare slumped to RMB99bn in November2017, down 16% YoY, compared with RMB118bn (up 23% YoY) in November2016, and RMB96bn (up 35% YoY) in November 2015.

We highlight that the annual growth rate was 10.4% in 2016 vs. 18.1% YoY in2015 and 9.8% YoY in 2014.

Figure 4: Monthly government spending on healthcare(January 2014 – November 2017)

Figure 5: Figure 5: Annual government spending onhealthcare (2000 – 2016)

-50%

-40%

-30%

-20%

-10%

0%

10%

20%

30%

40%

50%

0

25

50

75

100

125

150

175

200

225

250

RMB bn Monthly Govt spending YoY growth

49 57 64 78 85 104 132 199

276

399

480

643 720

821

1,009

1,192

1,315

0

100

200

300

400

500

600

700

800

900

1000

1100

1200

1300

1400

RMB bn

2000-16 CAGR: 23%

Source: Deutsche Bank, Ministry of Finance PRC Source: Deutsche Bank, Ministry of Finance PRC

Page 4 Deutsche Bank AG/Hong Kong

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17 January 2018

Health Care

China Healthcare

Figure 6: Monthly government spending on healthcare (January 2014 –November 2017)

RMB bn Monthly MoM % YoY % Annual YoY % YTD YoY %

Jan-14 51 -63% 46% 51 23%

Feb-14 53 4% 30% 103 23%

Mar-14 114 117% 38% 217 26%

Apr-14 77 -32% 8% 295 19%

May-14 88 14% 34% 383 19%

Jun-14 107 21% 26% 490 18%

Jul-14 63 -42% 11% 553 16%

Aug-14 61 -3% 10% 614 14%

Sep-14 85 39% 16% 699 12%

Oct-14 57 -33% 0% 756 10%

Nov-14 71 25% 17% 827 10%

Dec-14 1,009 9.8% 1,009

Jan-15 51 -72% 1% 51 1%

Feb-15 66 29% 25% 117 13%

Mar-15 129 97% 13% 246 13%

Apr-15 101 -22% 30% 347 18%

May-15 100 -1% 13% 446 16%

Jun-15 134 35% 25% 580 18%

Jul-15 79 -41% 26% 659 19%

Aug-15 74 -6% 22% 734 19%

Sep-15 106 42% 24% 839 20%

Oct-15 73 -31% 27% 912 21%

Nov-15 96 32% 35% 1,007 22%

Dec-15 1,192 18.1% 1,192

Jan-16 73 -60% 43% 73 43%

Feb-16 73 0% 11% 146 25%

Mar-16 171 134% 32% 318 29%

Apr-16 107 -38% 6% 424 22%

May-16 117 9% 17% 541 21%

Jun-16 177 52% 32% 718 24%

Jul-16 74 -58% -7% 792 20%

Aug-16 87 18% 18% 879 20%

Sep-16 138 58% 31% 1,016 21%

Oct-16 63 -54% -13% 1,079 18%

Nov-16 118 88% 23% 1,198 19%

Dec-16 -36% 1,315 10.4% 1,315

Jan-17 93 -22% 27% 93 27%

Feb-17 93 0% 27% 185 27%

Mar-17 226 144% 32% 411 29%

Apr-17 104 -54% -2% 515 21%

May-17 131 25% 12% 645 19%

Jun-17 217 66% 22% 862 20%

Jul-17 76 -65% 4% 939 19%

Aug-17 93 21% 6% 1,031 17%

Sep-17 152 64% 10% 1,183 16%

Oct-17 50 -67% -20% 1,234 14%

Nov-17 99 97% -16% 1,333 11%

Source: Deutsche Bank, Ministry of Finance PRC

Deutsche Bank AG/Hong Kong Page 5

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17 January 2018

Health Care

China Healthcare

Urban basic medicalinsurance fund inflow/outflowInflow/outflow up 27%/41% in November 2017

UBMI fund inflow and outflow climbed 27% and 41% YoY, respectively, inNovember 2017, vs. 11% and 9% in November 2016. For YTD10m17, UBMI fundinflow and outflow increased 42% and 35%, respectively, vs. 15% and 13% forYTD10m16.

Figure 7: UBMI fund inflow and outflow (January 2014 – November 2017)

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

0

50

100

150

200

250

Jan

-14

Mar-

14

May-1

4

Ju

l-14

Sep

-14

No

v-1

4

Jan

-15

Mar-

15

May-1

5

Ju

l-15

Sep

-15

No

v-1

5

Jan

-16

Mar-

16

May-1

6

Ju

l-16

Sep

-16

No

v-1

6

Jan

-17

Mar-

17

May-1

7

Ju

l-17

Sep

-17

No

v-1

7

UBMI fund inflow UBMI fund outflow

YoY growth (%) of fund inflow YoY growth (%) of fund outflowRMB bn

Source: Deutsche Bank, MOHRSS

Page 6 Deutsche Bank AG/Hong Kong

Page 7: China Healthcare Industrypg.jrj.com.cn › acc › Res › CN_RES › INDUS › 2018 › 1 › 17 › 292fa220-8… · 17-01-2018  · Health Care Industry Update Asia Japan North

17 January 2018

Health Care

China Healthcare

Vitamin C priceDomestic VC prices at high levels

The ASP of domestic vitamin C slightly increased to RMB72.5/kg in December2017, up 3.6% MoM and up 38% YoY. The surge from Nov 16 to April 17 wasdue to the suspension of production at major vitamin C manufacturers in theShijiazhuang province due to environmental concerns. The increase was short-lived, as producers reallocated production facilities and labor. Previously, the priceof vitamin C (VC) plummeted 80% from a peak of about RMB140/kg in 2008 tobelow RMB30/kg in 2012. This was driven by fierce competition and oversupplyin the market.

The average export price of vitamin C was USD7.0/kg in November 2017, thesame as that in October. The high domestic vitamin C price recently has led to asimultaneous increase in VC price for exports.

As manufacturers are immediately responding to the supply interruption, weexpect the price of vitamin C to be volatile in the near term.

Figure 8: Domestic VC price (July 2008 – December2017)

Figure 9: Average export VC price (January 2008 –November 2017)

0

20

40

60

80

100

120

140

160

RMB/kg

0

10

20

30

40

50

60

70

80

RMB/kg

Source: Deutsche Bank, Wind Source: Deutsche Bank, Wind

Deutsche Bank AG/Hong Kong Page 7

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17 January 2018

Health Care

China Healthcare

Active pharmaceuticalingredient (API) pricingBoth 6-APA and 7-ACA prices were flat in December

6-APA (aminopenicillanic acid) is the core active pharmaceutical ingredient (API) inpenicillin antibiotics. It is a by-product of corn. 7-ACA (aminocephalosporanic acid)is the core API in cephalosporins antibiotics.

6-APA price unchanged in December 2017The price of 6-APA remained the same at RMB230/kg in December 2017. It hasbeen trading at around RMB210/kg since 2010. The price of 6-APA has fluctuatedsince January 2011 within a range of RMB215/kg (January 2011) to RMB133/kg(July 2016).

2018 viewWe continue to expect relatively stable ASP, with a modest likelihood ofappreciation due to continued government tightening of antibiotics usage. Theprice of 6-APA has been declining after an uptrend in 1H14. We expect restrictionson the use of antibiotics to continue.

Figure 10: 6-APA price (January 2010 – December 2017) Figure 11: 6-APA price (January 2014 – December 2017)

0

100

200

300

400

RMB/kg

100

120

140

160

180

200

220

240

RMB/kg

Source: Deutsche Bank, www.healthtoo.com Source: Deutsche Bank, www.healthtoo.com

7-ACA price was flat in December 2017The price of 7-ACA dipped 14% to RMB420/kg last February; it continued to dropin the following months to a low of RMB335/kg. In June 2017, however, the priceincreased 43% to RMB480/kg.

The price of 7-ACA declined every month between November 2010 and February2012 due to restrictions on the use of cephalosporin antibiotics in China and largecapacity increases at 7-ACA facilities. It subsequently increased steadily.

In December 2017, the price of 7-ACA was kept stable at RMB450/kg amid stricterenvironmental policy. The current price is 58% below the peak of RMB930/kg(December 2010) and 7% above the previous trough of RMB420/kg (March 2016).

Page 8 Deutsche Bank AG/Hong Kong

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17 January 2018

Health Care

China Healthcare

Figure 12: 7-ACA price (January 2010 – December 2017) Figure 13: 7-ACA price (January 2014 – December 2017)

0

200

400

600

800

1,000

RMB/kg

0

100

200

300

400

500

600

700

800

RMB/kg

Source: Deutsche Bank, www.healthtoo.com Source: Deutsche Bank, www.healthtoo.com

Corn price was stable in December 2017The corn price in China started to increase at the beginning of 2009. It reacheda high of RMB2,600/ton in the 38th week of 2011. After that, the price traded ina range of RMB2,250-2,550/ton. It reached a new peak of RMB2,620/ton in the34th week of 2014, and then declined 10% to RMB2,340/ton at the end of 2014.It increased steadily to RMB2,440/ton in March 2015, before falling to RMB1,480/ton in January 2017. For 2017, the corn price was on an uptrend in 1H17, andwas relatively stable in 2H17, recording RMB1,690/ton in December.

Figure 14: Weekly corn prices in China (January 2011 – December 2017)

1,000

1,500

2,000

2,500

3,000

W1

2011

W27 W1

2012

W27 W1

2013

W27 W1

2014

W27 W1

2015

W27 W1

2016

W27 W1

2017

W27

RMB/ton

Source: Source: Bloomberg Finance LP, China JCI

Deutsche Bank AG/Hong Kong Page 9

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17 January 2018

Health Care

China Healthcare

Figure 15: Weekly corn prices in China (January 2009 – December 2017)

Weekly data

RMB/ton YTD

2009 1480 1500 1570 1650 1630 1630 1650 1720 1730 1770 1730 1750 1810 22%

2010 1820 1830 1820 1910 1940 2010 1930 1980 2030 2000 2000 2070 2050 13%

2011 2060 2080 2150 2170 2190 2270 2320 2310 2380 2510 2410 2260 2330 13%

2012 2330 2410 2450 2470 2430 2410 2440 2500 2510 2470 2320 2400 2430 4%

2013 2430 2420 2380 2360 2330 2380 2380 2390 2360 2410 2320 2330 2340 -4%

2014 2330 2350 2360 2360 2400 2440 2450 2550 2600 2560 2430 2360 2340 0%

2015 2340 2340 2320 2440 2430 2430 2400 2380 2360 2300 2000 2000 2110 -10%

2016 2100 2050 2050 1930 1880 1850 1880 1900 1810 1860 1680 1750 1710 -19%

2017 1520 1500 1490 1560 1630 1750 1700 1710 1680 1680 1730 1690 1690 11%

Weekly: Year-over-year growth

Total

2010 23% 22% 16% 16% 19% 23% 17% 15% 17% 13% 16% 18% 13% 13%

2011 13% 14% 18% 14% 13% 13% 20% 17% 17% 26% 21% 9% 14% 14%

2012 13% 16% 14% 14% 11% 6% 5% 8% 5% -2% -4% 6% 4% 4%

2013 4% 0% -3% -4% -4% -1% -2% -4% -6% -2% 0% -3% -4% -4%

2014 -4% -3% -1% 0% 3% 3% 3% 7% 10% 6% 5% 1% 0% 0%

2015 0% 0% -2% 3% 1% 0% -2% -7% -9% -10% -18% -15% -10% -10%

2016 -10% -12% -12% -21% -23% -24% -22% -20% -23% -19% -16% -13% -19% -19%

2017 -28% -27% -27% -19% -13% -5% -10% -10% -7% -10% 3% -3% -1% -1%

Source: Bloomberg Finance LP, China JCI

Page 10 Deutsche Bank AG/Hong Kong

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17 January 2018

Health Care

China Healthcare

TCM raw material pricesTCM Materials Market Price Index

The TCM Materials Market Price Index is the first price index covering traditionalChinese medicine raw materials to be approved in China and the first nationalprice index (out of the 12 released by the NDRC) created by a large privatecompany in China.

Index has surged since inceptionAs of December 2017, the China TCM index registered at 1,266, down 1.32%MoM. Since inception, it has been on a steady uptrend, with MoM growth rangingfrom 0.01% to 3.6%. However, it trended down for eight consecutive months inApril-November 2015, before picking up from December 2016.

Figure 16: China TCM Index (October 2012 - December 2017)

980

1,030

1,080

1,130

1,180

1,230

1,280

1,330

TCM Raw Material Index

Source: Deutsche Bank, www.cnkmprice.com

Individual TCM raw material price trends were mixed

Honeysuckle (flos lonicerae) price unchanged in DecemberHoneysuckle, or flos lonicerae, is a key element used to treat influenza and is theprimary raw material in Qing Kai Ling products.

The price of honeysuckle was RMB155/kg in December 2017, flat vs. the previousmonth. The price is now 46% below its February 2010 peak of RMB340/kg (afterwhich it stabilized from August 2010 to April 2011). We believe prices could fallback to January 2008 levels, the lowest we have seen. Prices increased fromRMB70/kg in January 2008 to RMB340/kg in February 2010. Seasonally weakdemand dragged the price down to RMB187/kg in June 2010; it then picked upslightly in the peak influenza season.

Deutsche Bank AG/Hong Kong Page 11

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17 January 2018

Health Care

China Healthcare

Figure 17: Flos Ionicerae (January 2012 – December2017)

Figure 18: Flos Ionicerae (January 2012 – December2017)

0

50

100

150

200

250

300

350

400

RMB/kg

Flos lonicerae

0

20

40

60

80

100

120

140

160

180

Fos lonicerae

RMB/kg

Source: Deutsche Bank, www.zgycsc.com Source: Source: Deutsche Bank, www.zgycsc.com

Indigowoad root (radix isatidis) price further declined in DecemberIndigowoad root, or radix isatidis, is a major raw material used in Qing Kai Lingproducts. It is often used to treat laryngitis and pharyngitis.

The price of indigowoad root declined to RMB7.5/kg in December 2017, down 4%MoM. The price surged from November 2009 (RMB13/kg) to a peak in May 2010(RMB27.25/kg). After this peak, it declined 65% to RMB11/kg in December 2014,down 21% from end-2010. According to industry sources, the price returned tonormal as the effects of the flux faded after 2009, while the recent dip can bemainly attributed to the current oversupply in the market.

Figure 19: Radix isatidis (June 2008 – December 2017) Figure 20: Radix isatidis (January 2012 – December2017)

0

5

10

15

20

25

30Radix isatidis

RMB/kg

0

2

4

6

8

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12

14

Radix isatidisRMB/kg

Source: Deutsche Bank, www.zgycsc.com Source: Deutsche Bank, www.zgycsc.com

Ophiopogon root (radix ophiopogonis) price was flat in DecemberOphiopogon root, or radix ophiopogonis, is often used with red ginseng to reduceperspiration and moisten the lungs and body. It is a major ingredient in Shen Maiproducts.

The price of ophiopogon root remained the same at RMB80/kg in December.Ophiopogon root has been a hot topic in the TCM raw material market, as itsprice spiked (908%) from a trough in March 2008 to a July 2011 peak due to a

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substantial reduction in planting area. The price peaked twice in 2011, at RMB139/kg in April 2011 and RMB145/kg in July 2011. Since the peak in mid-2011, theprice has fallen about 50%. The surge in price restrained demand, which webelieve depressed prices thereafter.

Figure 21: Radix ophiopogonis (January 2008 –December 2017)

Figure 22: Radix ophiopogonis (January 2012 –December 2017)

0

20

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140

160Radix ophiopogonis

RMB/kg

0

10

20

30

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60

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90Radix ophiopogonis

RMB/kg

Source: Deutsche Bank, www.zgycsc.com Source: Deutsche Bank, www.zgycsc.com

ASP of radix ginseng (red ginseng) declined marginally in DecemberRed ginseng, or radix ginseng, is a major ingredient in Shen Mai products and isused to invigorate the central nervous system, leading to increased energy andcirculation.

The price of red ginseng declined 3% MoM to RMB155/kg in December 2017.There was a 176% surge throughout 2010 and up to August 2011, when the pricepeaked at RMB215/kg, before it declined 26% to RMB160/kg in March 2013. Fromlate-2013, the price increased steadily to reach a historical high of RMB380/kg inJanuary 2015. However, it has declined rapidly since July 2015.

Figure 23: Red ginseng (January 2009 – December2017)

Figure 24: Red ginseng (January 2012 – December2017)

0

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0

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400Red ginseng

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Source: Deutsche Bank, www.zgycsc.com Source: Deutsche Bank, www.zgycsc.com

Deutsche Bank AG/Hong Kong Page 13

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Commercial healthcareinsurance inflow/outflowInflow and outflow increased 36% and 32% YoYrespectively in November 2017

Growth of commercial healthcare insurance inflow had accelerated sinceSeptember 2017 and reached 36% YoY in November, vs. 5% and 68% inYTD10m17 and 2016, respectively. Growth in commercial healthcare insuranceoutflow was 32% in November 2017, vs. 29% and 31% in YTD10m17 and 2016,respectively. We define inflow as the sum of insurance premiums collected andoutflow as the sum of claims settled. We remind investors that commercialhealthcare insurance represents approximately 1.5% of China’s entire healthcareexpenditure.

Figure 25: Commercial healthcare insurance inflow andoutflow (January 2013 – November 2017)

Figure 26: Total commercial insurance inflow andoutflow (January 2013 – November 2017)

-40%

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Outflow YoY growth (RHS) Inflow YoY growth (RHS)RMB bn

-10%

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Total insurance inflow Total insurance outflow

Inflow YoY growth (RHS) Outflow YoY growth (RHS)

RMB bn

Source: Deutsche Bank, China insurance regulatory commission Source: Deutsche Bank, China insurance regulatory commission

Figure 27: Total commercial insurance inflow breakdown(January 2013 – November 2017)

Figure 28: Total commercial insurance outflowbreakdown (January 2013 – November 2017)

-40%

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0%

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80%

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600

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800

900

Total insurance (LHS) Life insurance(LHS)

Healthcare insurance (LHS) Total insurance YOY (RHS)

Life insurance YOY (RHS) Healthcare insurance YoY (RHS)RMB bn

-20%

-10%

0%

10%

20%

30%

40%

50%

60%

70%

80%

0

20

40

60

80

100

120

140

Total insurance (LHS) Life insurance(LHS)

Healthcare insurance (LHS) Total insurance YOY (RHS)

Life insurance YOY (RHS) Healthcare insurance YoY(RHS)RMB bn

Source: Deutsche Bank, China insurance regulatory commission Source: Deutsche Bank, China insurance regulatory commission

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Valuation and risks

Aier Eye: increasing TP to RMB38.1 from RMB35.2 (current price: RMB35.4);risksOur TP of RMB38.1 is based on 25x EV/EBITDA on 2019E EBITDA due to sectorre-rating. We believe the multiple is justified, as its Asia listed peers are tradingat 17x with 6% EBITDA growth in 2020E (vs. the 24% we model for Aier). Keyrisks include delays in geographical expansion, execution risk related to newly-acquired business, and slower ASP/ volume growth.

CSPC: increasing TP to HKD20.3 from RMB19.1 (current price: HKD18.1); risksOur TP is based on 34x 2018E EPS, due to higher visibility of key product launches.We believe the multiple is justified, as its HK-listed peers are trading at 23x with15% EPS growth in 2019E (vs. 22% for CSPC). Key risks include price cuts, slower-than-expected tender progress and pipeline delays.

Topchoice: increasing TP to RMB31.0 from RMB27.2 (current price: RMB36.2);risksOur TP is based on 30x EV/EBITDA on 2018E EBITDA. We have revised ourmultiple as comps for the sector have risen. We believe 30x is justified, as itsAsia-listed peers are trading at 20x with 7% growth in 2018 (vs. 21% we modelfor Topchoice). Key upside/downside risks include faster/slower-than-expectedpatient traffic growth, higher/lower ASP growth, and faster/slower ramp-up ofnew hospitals.

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Appendix 1

Important Disclosures

*Other information available upon request

*Prices are current as of the end of the previous trading session unless otherwise indicated and are sourced fromlocal exchanges via Reuters, Bloomberg and other vendors . Other information is sourced from Deutsche Bank, subjectcompanies, and other sources. For disclosures pertaining to recommendations or estimates made on securities other thanthe primary subject of this research, please see the most recently published company report or visit our global disclosurelook-up page on our website at http://gm.db.com/ger/disclosure/DisclosureDirectory.eqsr. Aside from within this report,important conflict disclosures can also be found at https://gm.db.com/equities under the "Disclosures Lookup" and "Legal"tabs. Investors are strongly encouraged to review this information before investing.

Analyst Certification

The views expressed in this report accurately reflect the personal views of the undersigned lead analyst about the subjectissuers and the securities of those issuers. In addition, the undersigned lead analyst has not and will not receive anycompensation for providing a specific recommendation or view in this report. Jack Hu

Equity Rating Key Equity rating dispersion and banking relationships

Buy: Based on a current 12- month view of total share-holderreturn (TSR = percentage change in share price from currentprice to projected target price plus pro-jected dividend yield ) ,we recommend that investors buy the stock.Sell: Based on a current 12-month view of total share-holderreturn, we recommend that investors sell the stock.Hold: We take a neutral view on the stock 12-months out and,based on this time horizon, do not recommend either a Buyor Sell.

Newly issued research recommendations and target pricessupersede previously published research.

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Additional Information

The information and opinions in this report were prepared by Deutsche Bank AG or one of its affiliates (collectively"Deutsche Bank"). Though the information herein is believed to be reliable and has been obtained from public sourcesbelieved to be reliable, Deutsche Bank makes no representation as to its accuracy or completeness. Hyperlinks to third-party websites in this report are provided for reader convenience only. Deutsche Bank neither endorses the content noris responsible for the accuracy or security controls of those websites.??If you use the services of Deutsche Bank in connection with a purchase or sale of a security that is discussed in this report,or is included or discussed in another communication (oral or written) from a Deutsche Bank analyst, Deutsche Bank mayact as principal for its own account or as agent for another person.??Deutsche Bank may consider this report in deciding to trade as principal. It may also engage in transactions, for itsown account or with customers, in a manner inconsistent with the views taken in this research report. Others withinDeutsche Bank, including strategists, sales staff and other analysts, may take views that are inconsistent with those takenin this research report. Deutsche Bank issues a variety of research products, including fundamental analysis, equity-linkedanalysis, quantitative analysis and trade ideas. Recommendations contained in one type of communication may differfrom recommendations contained in others, whether as a result of differing time horizons, methodologies, perspectivesor otherwise. Deutsche Bank and/or its affiliates may also be holding debt or equity securities of the issuers it writeson. Analysts are paid in part based on the profitability of Deutsche Bank AG and its affiliates, which includes investmentbanking, trading and principal trading revenues.??Opinions, estimates and projections constitute the current judgment of the author as of the date of this report. They donot necessarily reflect the opinions of Deutsche Bank and are subject to change without notice. Deutsche Bank providesliquidity for buyers and sellers of securities issued by the companies it covers. Deutsche Bank research analysts sometimeshave shorter-term trade ideas that may be inconsistent with Deutsche Bank's existing longer-term ratings. Trade ideasfor equities can be found at the SOLAR link at http://gm.db.com. A SOLAR idea represents a high-conviction belief by ananalyst that a stock will outperform or underperform the market and/or a specified sector over a time frame of no less thantwo weeks and no more than six months. In addition to SOLAR ideas, analysts may occasionally discuss with our clients,and with Deutsche Bank salespersons and traders, trading strategies or ideas that reference catalysts or events that mayhave a near-term or medium-term impact on the market price of the securities discussed in this report, which impactmay be directionally counter to the analysts' current 12-month view of total return or investment return as describedherein. Deutsche Bank has no obligation to update, modify or amend this report or to otherwise notify a recipient thereofif an opinion, forecast or estimate changes or becomes inaccurate. Coverage and the frequency of changes in marketconditions and in both general and company-specific economic prospects make it difficult to update research at definedintervals. Updates are at the sole discretion of the coverage analyst or of the Research Department Management, and themajority of reports are published at irregular intervals. This report is provided for informational purposes only and doesnot take into account the particular investment objectives, financial situations, or needs of individual clients. It is not anoffer or a solicitation of an offer to buy or sell any financial instruments or to participate in any particular trading strategy.Target prices are inherently imprecise and a product of the analyst ’ s judgment. The financial instruments discussedin this report may not be suitable for all investors, and investors must make their own informed investment decisions.Prices and availability of financial instruments are subject to change without notice, and investment transactions can leadto losses as a result of price fluctuations and other factors. If a financial instrument is denominated in a currency otherthan an investor's currency, a change in exchange rates may adversely affect the investment. Past performance is notnecessarily indicative of future results. Performance calculations exclude transaction costs, unless otherwise indicated.Unless otherwise indicated, prices are current as of the end of the previous trading session and are sourced from localexchanges via Reuters, Bloomberg and other vendors. Data is also sourced from Deutsche Bank, subject companies, andother parties.??The Deutsche Bank Research Department is independent of other business divisions of the Bank. Details regardingorganizational arrangements and information barriers we have established to prevent and avoid conflicts of interest withrespect to our research are available on our website under Disclaimer, found on the Legal tab.??

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Macroeconomic fluctuations often account for most of the risks associated with exposures to instruments that promiseto pay fixed or variable interest rates. For an investor who is long fixed-rate instruments (thus receiving these cashflows), increases in interest rates naturally lift the discount factors applied to the expected cash flows and thuscause a loss. The longer the maturity of a certain cash flow and the higher the move in the discount factor, thehigher will be the loss. Upside surprises in inflation, fiscal funding needs, and FX depreciation rates are among themost common adverse macroeconomic shocks to receivers. But counterparty exposure, issuer creditworthiness, clientsegmentation, regulation (including changes in assets holding limits for different types of investors), changes in taxpolicies, currency convertibility (which may constrain currency conversion, repatriation of profits and/or liquidation ofpositions), and settlement issues related to local clearing houses are also important risk factors. The sensitivity of fixed-income instruments to macroeconomic shocks may be mitigated by indexing the contracted cash flows to inflation, toFX depreciation, or to specified interest rates – these are common in emerging markets. The index fixings may – byconstruction – lag or mis-measure the actual move in the underlying variables they are intended to track. The choice ofthe proper fixing (or metric) is particularly important in swaps markets, where floating coupon rates (i.e., coupons indexedto a typically short-dated interest rate reference index) are exchanged for fixed coupons. Funding in a currency that differsfrom the currency in which coupons are denominated carries FX risk. Options on swaps (swaptions) the risks typical tooptions in addition to the risks related to rates movements.??Derivative transactions involve numerous risks including market, counterparty default and illiquidity risk. Theappropriateness of these products for use by investors depends on the investors' own circumstances, including theirtax position, their regulatory environment and the nature of their other assets and liabilities; as such, investors shouldtake expert legal and financial advice before entering into any transaction similar to or inspired by the contents of thispublication. The risk of loss in futures trading and options, foreign or domestic, can be substantial. As a result of thehigh degree of leverage obtainable in futures and options trading, losses may be incurred that are greater than theamount of funds initially deposited – up to theoretically unlimited losses. Trading in options involves risk and is notsuitable for all investors. Prior to buying or selling an option, investors must review the "Characteristics and Risks ofStandardized Options”, at http://www.optionsclearing.com/about/publications/character-risks.jsp. If you are unable toaccess the website, please contact your Deutsche Bank representative for a copy of this important document.??Participants in foreign exchange transactions may incur risks arising from several factors, including: (i) exchange rates canbe volatile and are subject to large fluctuations; (ii) the value of currencies may be affected by numerous market factors,including world and national economic, political and regulatory events, events in equity and debt markets and changes ininterest rates; and (iii) currencies may be subject to devaluation or government-imposed exchange controls, which couldaffect the value of the currency. Investors in securities such as ADRs, whose values are affected by the currency of anunderlying security, effectively assume currency risk.??Deutsche Bank is not acting as a financial adviser, consultant or fiduciary to you or any of your agents with respect toany information provided in this report. Deutsche Bank does not provide investment, legal, tax or accounting advice, andis not acting as an impartial adviser. Information contained herein is being provided on the basis that the recipient willmake an independent assessment of the merits of any investment decision, and is not meant for retirement accounts orfor any specific person or account type. The information we provide is directed only to persons we believe to be financiallysophisticated, who are capable of evaluating investment risks independently, both in general and with regard to particulartransactions and investment strategies, and who understand that Deutsche Bank has financial interests in the offering ofits products and services. If this is not the case, or if you or your agent are an IRA or other retail investor receiving thisdirectly from us, we ask that you inform us immediately.

Unless governing law provides otherwise, all transactions should be executed through the Deutsche Bank entity in theinvestor's home jurisdiction. Aside from within this report, important risk and conflict disclosures can also be found athttps://gm.db.com on each company ’ s research page and under the "Disclosures Lookup" and "Legal" tabs. Investorsare strongly encouraged to review this information before investing.

United States: Approved and/or distributed by Deutsche Bank Securities Incorporated, a member of FINRA, NFA and SIPC.Analysts located outside of the United States are employed by non-US affiliates that are not subject to FINRA regulations,including those regarding contacts with issuer companies.??

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Germany: Approved and/or distributed by Deutsche Bank AG, a joint stock corporation with limited liability incorporatedin the Federal Republic of Germany with its principal office in Frankfurt am Main. Deutsche Bank AG is authorized underGerman Banking Law and is subject to supervision by the European Central Bank and by BaFin, Germany ’ s FederalFinancial Supervisory Authority.??United Kingdom: Approved and/or distributed by Deutsche Bank AG acting through its London Branch at WinchesterHouse, 1 Great Winchester Street, London EC2N 2DB. Deutsche Bank AG in the United Kingdom is authorised by thePrudential Regulation Authority and is subject to limited regulation by the Prudential Regulation Authority and FinancialConduct Authority. Details about the extent of our authorisation and regulation are available on request.??Hong Kong: Distributed by Deutsche Bank AG, Hong Kong Branch or Deutsche Securities Asia Limited (save that anyresearch relating to futures contracts within the meaning of the Hong Kong Securities and Futures Ordinance Cap. 571shall be distributed solely by Deutsche Securities Asia Limited). The provisions set out above in the "Additional Information"section shall apply to the fullest extent permissible by local laws and regulations, including without limitation the Code ofConduct for Persons Licensed or Registered with the Securities and Futures Commission. .??India: Prepared by Deutsche Equities India Private Limited (DEIPL) having CIN: U65990MH2002PTC137431 and registeredoffice at 14th Floor, The Capital, C-70, G Block, Bandra Kurla Complex Mumbai (India) 400051. Tel: + 91 22 71804444. It is registered by the Securities and Exchange Board of India (SEBI) as a Stock broker bearing registrationnos.: NSE (Capital Market Segment) - INB231196834, NSE (F&O Segment) INF231196834, NSE (Currency DerivativesSegment) INE231196834, BSE (Capital Market Segment) INB011196830; Merchant Banker bearing SEBI Registrationno.: INM000010833 and Research Analyst bearing SEBI Registration no.: INH000001741. DEIPL may have receivedadministrative warnings from the SEBI for breaches of Indian regulations. The transmission of research through DEIPLis Deutsche Bank's determination and will not make a recipient a client of DEIPL. Deutsche Bank and/or its affiliate(s)may have debt holdings or positions in the subject company. With regard to information on associates, please refer to the“Shareholdings” section in the Annual Report at: https://www.db.com/ir/en/annual-reports.htm.??Japan: Approved and/or distributed by Deutsche Securities Inc.(DSI). 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Beforedeciding on the purchase of financial products and/or services, customers should carefully read the relevant disclosures,prospectuses and other documentation. "Moody's", "Standard & Poor's", and "Fitch" mentioned in this report are notregistered credit rating agencies in Japan unless Japan or "Nippon" is specifically designated in the name of the entity.Reports on Japanese listed companies not written by analysts of DSI are written by Deutsche Bank Group's analysts withthe coverage companies specified by DSI. Some of the foreign securities stated on this report are not disclosed accordingto the Financial Instruments and Exchange Law of Japan. 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Taiwan: Information on securities/investments that trade in Taiwan is for your reference only. Readers shouldindependently evaluate investment risks and are solely responsible for their investment decisions. Deutsche Bank researchmay not be distributed to the Taiwan public media or quoted or used by the Taiwan public media without written consent.Information on securities/instruments that do not trade in Taiwan is for informational purposes only and is not to beconstrued as a recommendation to trade in such securities/instruments. Deutsche Securities Asia Limited, Taipei Branchmay not execute transactions for clients in these securities/instruments.??Qatar: Deutsche Bank AG in the Qatar Financial Centre (registered no. 00032) is regulated by the Qatar Financial CentreRegulatory Authority. Deutsche Bank AG - QFC Branch may undertake only the financial services activities that fall withinthe scope of its existing QFCRA license. Its principal place of business in the QFC: Qatar Financial Centre, Tower, WestBay, Level 5, PO Box 14928, Doha, Qatar. This information has been distributed by Deutsche Bank AG. Related financialproducts or services are only available only to Business Customers, as defined by the Qatar Financial Centre RegulatoryAuthority.??Russia: The information, interpretation and opinions submitted herein are not in the context of, and do not constitute, anyappraisal or evaluation activity requiring a license in the Russian Federation.

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David Folkerts-LandauGroup Chief Economist and Global Head of Research

Raj HindochaGlobal Chief Operating Officer

Research

Michael SpencerHead of APAC Research

Global Head of Economics

Steve PollardHead of Americas Research

Global Head of Equity Research

Anthony KlarmanGlobal Head ofDebt Research

Paul ReynoldsHead of EMEA

Equity Research

Dave ClarkHead of APAC

Equity Research

Pam FinelliGlobal Head of

Equity Derivatives Research

Andreas NeubauerHead of Research - Germany

Spyros MesomerisGlobal Head of Quantitative

and QIS Research

International Production Locations

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