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Enantioselective synthesesO 0031 The Highly Enantioselective Phase-Transfer Catalytic Mono-Alkylation of
Malonamic Esters. — A facile and highly enantioselective synthesis of chiral esters (III) by a phase-transfer catalytic alkylation of malonamic esters (I) is developed. De-rivatives (III) are convenient precursors in the synthesis of a chiral aminoalcohol (VI) and hydroxy ester (IX). — (KIM, M.-H.; CHOI, S.-H.; LEE, Y.-J.; LEE, J.; NAHM, K.; JEONG, B.-S.; PARK*, H.-G.; JEW, S.-S.; Chem. Commun. (Cambridge) 2009, 7, 782-784; Res. Inst. Pharm. Sci., Coll. Pharm., Seoul Natl. Univ., Kwanak, Seoul 151-742, S. Korea; Eng.) — R. Staver
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ChemInform 2009, 40, issue 25 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
