1997 halogen compounds

halogen compounds (benzene compounds)Q 0090

04 - 097Synthesis of Fluorine Compounds Using Zinc Complex of Halothane.— CF3CBrCl-containing alcohols (III), are synthesized by Zn-mediatedreaction of aldehydes (I) and halothane (II) and transformed smoothly into the(Z)-olefin (VII). Both the compounds (III) and (VII) are useful synthons for thesynthesis of fluorine analogues of pyrethroids. — (TAKAGI, T.; NAKAMOTO,M.; SATO, K.; KOYAMA, M.; ANDO, A.; KUMADAKI, I.; Tetrahedron 52(1996) 39, 12667-12676; Fac. Pharm. Sci., Setsunan Univ., Hirakata, Osaka573-01, Japan; EN)

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