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AntibioticsU 1200 DOI: 10.1002/chin.201131198
Synthesis and Antibacterial Activity of New 4''-O-Carbamates of 11,12-Cyclic Carbonate Erythromycin A 6,9-Imino Ether. — All target compounds (I) show po-tent activities against erythromycin-susceptible S.pneumoniae comparable to erythro-mycin A, clarithromycin and azithromycin, Additionally, the new imino ethers exhibit improved activities against erythromycin-resistant S.pneumoniae B1 and AB11 com-pared with erythromycin A and azithromycin. — (ZHANG, L.; JIAO, B.; YANG, X.; LIU, L.; MA*, S.; J. Antibiot. 64 (2011) 3, 243-247, http://dx.doi.org/10.1038/ja.2010.166 ; Dep. Med. Chem., Sch. Pharm. Sci., Shandong Univ., Jinan, Shandong 250012, Peop. Rep. China; Eng.) — C. Cyrus
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ChemInform 2011, 42, issue 31 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim