2001 amino acids, peptides

amino acids, peptidesU 0400

44 - 201Discovery and SAR of Org 24598 – A Selective Glycine UptakeInhibitor. — Org 24598, the (R)-isomer of compound (IV), is found to bea highly selective inhibitor of hGlyT-1b with negligible action at GlyT-2 andother transporters and receptors. — (BROWN, ANGUS; CARLYLE, IAN;CLARK, JOHN; HAMILTON, WILLIAM; GIBSON, SAMUEL; MCGARRY,GEORGE; MCEACHEN, SANDRA; RAE, DUNCAN; THORN, SIMON;WALKER, GLENN; Bioorg. Med. Chem. Lett. 11 (2001) 15, 2007-2009; Med.Chem. Dep., Organon Lab. Ltd., Newhouse, Motherwell ML1 5SH, UK; EN)

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