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Triazole derivativesR 0280 Copper-Catalyzed Cycloaddition of Sulfonyl Azides with Alkynes to Synthesize

N-Sulfonyltriazoles "On Water" at Room Temperature. — The procedure is de-veloped for the reaction of water-insoluble substrates in aqueous media ("on water"). The liquid substrates show higher reaction rates than the solid ones. The alkynes (Ih), (Ii), first dissolved in EtOAc and then subjected to the standard conditions, afford the products in higher yields. — (WANG, F.; FU*, H.; JIANG, Y.; ZHAO, Y.; Adv. Synth. Catal. 350 (2008) 11-12, 1830-1834; Key Lab. Bioorg. Phosphorus Chem. Chem. Biol., Dep. Chem., Tsinghua Univ., Beijing 100084, Peop. Rep. China; Eng.) — Y. Steudel

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ChemInform 2008, 39, issue 50 © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim