View this journal online at

wileyonlinelibrary.com

C-C bond formationO 0282 DOI: 10.1002/chin.201103048

A Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading. — The present new catalyst system can be used for the direct arylation of various heteroaromatic compounds at low palla-dium loadings. Electron-rich, electron-poor, and polysubstituted furans (I) and (IV), thiophene (VI), thiazole (VIII), and pyrrole (X) are smoothly arylated tolerating chlo-roarenes bearing various functional groups in para-, meta- and ortho-positions. In some cases, the reaction can be performed with only 0.1 mol% catalyst loading albeit, yield of the resulting product is then clearly decreased. — (ROY, D.; MOM, S.; BEAUPERIN, M.; DOUCET, H.; HIERSO*, J.-C.; Angew. Chem., Int. Ed. 49 (2010) 37, 6650-6654, http://dx.doi.org/10.1002/anie.201002987 ; Inst. Chim. Mol., Univ. Bourgogne, F-21078 Dijon, Fr.; Eng.) — S. Adam

03- 048

ChemInform 2011, 42, issue 03 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim