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Chemistry UCSD Fall 2015
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Cellular division Regenerate damaged tissues Mitosis
Division of chromosomes into 2 nuclei Cytokinesis
Division of cytoplasm into 2 cells Genome
In bacteria, it has only 1 circular dna molecule, still considered a genome In Eukaryotics, it has chromosomes of linear dna molecule depending on the species, the
make up of dna molecule = genome Chromosomes
Packaged dna molecules Clicker 1 question
True Dna = manual book
Tells the cell how to behave Ex, the liver cell would open up a chapter on how to be a liver cell, etc.
Cellular organization Dna is double stranded Wraps around histones in order to form nucleosomes
Balls wrapped with dna strands Balls wrapped with dna strands (nucleosomes) wraps around1 itself = coiled coil chromatin
bundle Clicker 2
B. Clicker 3
B Chromosome is just a term for the MOST packaged DNA DNA has to be accessible for genes to be transcribed and for the cells to function properly
Importance of chromosomes Need chromosomes, condensed dna in order to be organized and easier to maneuver, less
messy, strands won’t get messy and tangled Microtubules = roads to move shit in cells Mitotic phase split into mitosis & cytokinesis
Mitotis Prophase, prometaphase, metaphase, anaphase, telophase,
Cytokinesis Overlaps with telophase
Interphase is alternated with the mitotic phase in the cell cycle. What is the interphase? Genome = total dna containing an organism’s complete set of genes Chromosome = 1 unit of double stranded dna, 1 set contains the genome Diploid = 2 sets of chromosomes. Maternal & paternal
Chromosomes condensed in G2 phased, in prep for cell division, Clicker 4
D, no need to duplicate chromosomes if they aren’t going to divide Neurons Can’t do anything with condensed dna material
Plant cells don’t have centrioles Youtube video mitosis Cell cycle must be tightly regulated
Ensure an organism’s function Cell type & turnover chat in lecture slide
Molecular control system = regulates eukaryotic cell cycle Experiment in lecture slide There is something in the cytoplasm that controls the cell’s phase
Clicker 5 A
Cell signaling Signaling molecule is a growth factor?
Lecture Part II