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Cellular division Regenerate damaged tissues Mitosis Division of chromosomes into 2 nuclei Cytokinesis Division of cytoplasm into 2 cells Genome In bacteria, it has only 1 circular dna molecule, still considered a genome In Eukaryotics, it has chromosomes of linear dna molecule depending on the species, the make up of dna molecule = genome Chromosomes Packaged dna molecules Clicker 1 question True Dna = manual book Tells the cell how to behave Ex, the liver cell would open up a chapter on how to be a liver cell, etc. Cellular organization Dna is double stranded Wraps around histones in order to form nucleosomes Balls wrapped with dna strands Balls wrapped with dna strands (nucleosomes) wraps around1 itself = coiled coil chromatin bundle Clicker 2 B. Clicker 3 B Chromosome is just a term for the MOST packaged DNA DNA has to be accessible for genes to be transcribed and for the cells to function properly Importance of chromosomes Need chromosomes, condensed dna in order to be organized and easier to maneuver, less messy, strands won’t get messy and tangled Microtubules = roads to move shit in cells

Chem 6C UCSD

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Chemistry UCSD Fall 2015

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Page 1: Chem 6C UCSD

Cellular division Regenerate damaged tissues Mitosis

Division of chromosomes into 2 nuclei Cytokinesis

Division of cytoplasm into 2 cells Genome

In bacteria, it has only 1 circular dna molecule, still considered a genome In Eukaryotics, it has chromosomes of linear dna molecule depending on the species, the

make up of dna molecule = genome Chromosomes

Packaged dna molecules Clicker 1 question

True Dna = manual book

Tells the cell how to behave Ex, the liver cell would open up a chapter on how to be a liver cell, etc.

Cellular organization Dna is double stranded Wraps around histones in order to form nucleosomes

Balls wrapped with dna strands Balls wrapped with dna strands (nucleosomes) wraps around1 itself = coiled coil chromatin

bundle Clicker 2

B. Clicker 3

B Chromosome is just a term for the MOST packaged DNA DNA has to be accessible for genes to be transcribed and for the cells to function properly

Importance of chromosomes Need chromosomes, condensed dna in order to be organized and easier to maneuver, less

messy, strands won’t get messy and tangled Microtubules = roads to move shit in cells Mitotic phase split into mitosis & cytokinesis

Mitotis Prophase, prometaphase, metaphase, anaphase, telophase,

Cytokinesis Overlaps with telophase

Interphase is alternated with the mitotic phase in the cell cycle. What is the interphase? Genome = total dna containing an organism’s complete set of genes Chromosome = 1 unit of double stranded dna, 1 set contains the genome Diploid = 2 sets of chromosomes. Maternal & paternal

Page 2: Chem 6C UCSD

Chromosomes condensed in G2 phased, in prep for cell division, Clicker 4

D, no need to duplicate chromosomes if they aren’t going to divide Neurons Can’t do anything with condensed dna material

Plant cells don’t have centrioles Youtube video mitosis Cell cycle must be tightly regulated

Ensure an organism’s function Cell type & turnover chat in lecture slide

Molecular control system = regulates eukaryotic cell cycle Experiment in lecture slide There is something in the cytoplasm that controls the cell’s phase

Clicker 5 A

Cell signaling Signaling molecule is a growth factor?

Lecture Part II