Upload
jerome-stevens
View
215
Download
1
Embed Size (px)
Citation preview
CHEE 340 Tutorial 1
Cell Structure and Metabolism
2
Cell Basics
• Cell Theory– All organisms are comprised of one or more cells– The cell is the smallest unit of life– All cells come from previously existing cells
• List 4 types of molecules synthesized by cells
18/09/2013 CHEE 340: Biomedical Engineering
3
Eukaryotic Cell
• The cytoplasm refers to the internal contents of a cell and is composed of ________ and _________.
18/09/2013 CHEE 340: Biomedical Engineering
CHEE 340: Biomedical Engineering 4
Organelles
• Nucleus• Ribosomes• Endoplasmic reticulum• Golgi apparatus• Mitochondria• Cytoskeleton
18/09/2013
5
Plasma Membrane
• Functions of the plasma membrane include:
• The plasma membrane is made up of ______________ which are amphipathic (_________ head and _______ tail) and combine tail-to-tail to form the _______________.
18/09/2013 CHEE 340: Biomedical Engineering
6
Transport
• List 4 ways that molecules can be transported across a cell membrane
• The cell membrane allows the cell to maintain both an _________ and an _________ balance between itself and the extracellular fluid.
• A typical cell environment has a high concentration of _____ions inside the cell and a high concentration of ______ and ______ ions in the extracellular fluid.
18/09/2013 CHEE 340: Biomedical Engineering
7
Receptors
• List 3 possible results of a ligand binding to a membrane-bound receptor–
• List 3 types of signalling–
18/09/2013 CHEE 340: Biomedical Engineering
8
Metabolism
• Cells require energy, which is generally provided by converting ______ to ______.
• Glucose metabolism requires _______ and consists of 2 phases: _________ and _________. It produces _____, _____, and ______.
• Lipid metabolism produces ______ energy than glucose metabolism.
18/09/2013 CHEE 340: Biomedical Engineering
9
Energy storage
• Fat is stored in ________ for _______ use.• Glucose is stored as ________ for _______
use.
18/09/2013 CHEE 340: Biomedical Engineering
Relative Directions: ______________ and ________________
Anatomy
18/09/2013 CHEE 340: Biomedical Engineering 10
11
Anatomy
18/09/2013 CHEE 340: Biomedical Engineering
12
Tissue
• A tissue is an organized group of cells and extracellular matrix that perform a specialized activity
• Functions of the extracellular matrix:– – – – –
18/09/2013 CHEE 340: Biomedical Engineering
13
Extracellular Matrix
• Consists of a network of _______ and __________.
• ________ are transmembrane proteins that act as matrix receptors and connect the ECM to the cell’s cytoskeleton.
18/09/2013 CHEE 340: Biomedical Engineering
14
Epithelial Tissue
• Functions:– – – – –
• Epithelial tissue that is 2+ cell layers thick is called ________________.
• Epithelial cells on internal surfaces are known as ________________.
18/09/2013 CHEE 340: Biomedical Engineering
15
Connective Tissues
• Connective tissues are ________________.• Connective tissues are primarily composed of
the _________________.• The connective tissue that connects muscles
to bone is called a _____________, while the tissue that connects bone to bone is called a _____________.
• _________ is a fluid connective tissue.
18/09/2013 CHEE 340: Biomedical Engineering
16
Blood
• Erythrocytes are also known as ___________.• Thrombocytes are also known as __________
and are involved in ____________.• ___________ are the “first responders” of the
immune system.• Monocytes differentiate into ____________
and help defend against ________________.• _____________ are associated with the
“memory” of the immune system.18/09/2013 CHEE 340: Biomedical Engineering
17
Muscle and Nerve Tissues
• Muscle cells respond to ________________.• The three types of muscle tissue found in the
human body are ________, ________, and _________.
• Nervous tissue is composed of _______ and __________.
• ________ sense stimuli at the __________ and transmit electrical impulses (signals) along the _________ to other cells or tissues.
18/09/2013 CHEE 340: Biomedical Engineering
CHEE 340: Biomedical Engineering 18
Nerve Tissue
• _______ cells support, protect, and nourish neurons.
• For example, oligodendrocytes excrete an ECM material known as ___________ to provide electrical insulation of CNS neurons.
18/09/2013