Charles E. Trobman Oncology Data Management Center

We are pleased to share with you the staff of the Institute of Oncology publications over the

past 10 years showing some of the research activity supported by the data collection of the

Charles E. Trobman Oncology Data Management Center.

2005

1) Harefuah. 2005 Jul;144(7):482-8, 526.

[Treatment approach to localized esophageal cancer--what have we learned so far?]. [Article in Hebrew] Brenner B1, Purim O, Sulkes A.

2) Clin Cancer Res. 2005 May 15;11(10):3836-45.

A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. Shah MA1, Kortmansky J, Motwani M, Drobnjak M, Gonen M, Yi S, Weyerbacher A, Cordon-Cardo C, Lefkowitz R, Brenner B, O'Reilly E, Saltz L, Tong W, Kelsen DP, Schwartz GK.

3) J Clin Oncol. 2005 Mar 20;23(9):2038-48. Neoadjuvant chemotherapy before liver resection for patients with unresectable liver metastases from colorectal carcinoma. Leonard GD1, Brenner B, Kemeny NE.

4) Rev Invest Clin. 2005 Jan-Feb;57(1):100; author reply 101.

[Aarón Sulkes' comments made to Uscanga's paper]. [Article in Spanish] Sulkes A.

5) Isr Med Assoc J. 2005 Apr;7(4):257-61.

The emerging role of the new aromatase inhibitors in the treatment of breast cancer. Sulkes A1

6) Cancer J. 2005 Sep-Oct;11(5):390-8.

Body mass index predicts the incidence of radiation pneumonitis in breast cancer patients. Allen AM1, Prosnitz RG, Ten Haken RK, Normolle DP, Yu X, Zhou SM, Marsh R, Marks LB, Pierce LJ

7) Int J Oncol. 2005 Oct;27(4):1097-103.

Anti-proliferative activity of haloperidol in B16 mouse and human SK-MEL-28 melanoma cell lines.

Nordenberg J1, Perlmutter I, Lavie G, Beery E, Uziel O, Morgenstern C, Fenig E, Weizman A

8) Isr Med Assoc J. 2005 Jul;7(7):439-42.

Postoperative loco-regional radiation therapy for breast cancer patients with four or more involved lymph nodes or extracapsular extension. Evron E1, Barzily L, Rakowsky E, Ben-Baruch N, Sulkes J, Rizel S, Fenig E.

9) Isr Med Assoc J. 2005 Jun;7(6):377-80.

Treatment of rectal cancer by chemoradiation followed by surgery: analysis and early clinical outcome in 66 patients. Nudelman IL1, Fuko V, Geller A, Fenig E, Lelchuk S.

10) Pediatr Radiol. 2005 Sep;35(9):872-9. Epub 2005 May 26. Role of MRI in the management of children with diffuse pontine tumors: a study of 15 patients and review of the literature. Kornreich L1, Schwarz M, Karmazyn B, Cohen IJ, Shuper A, Michovitz S, Yaniv I, Fenig E, Horev G.

11) Br J Cancer. 2005 May 23;92(10):1881-91.

Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines. Uziel O1, Fenig E, Nordenberg J, Beery E, Reshef H, Sandbank J, Birenbaum M, Bakhanashvili M, Yerushalmi R, Luria D, Lahav M

12) Ann Otol Rhinol Laryngol. 2005 Feb;114(2):147-52. Complications of mastoiditis in children at the onset of a new millennium. Oestreicher-Kedem Y1, Raveh E, Kornreich L, Popovtzer A, Buller N, Nageris B

13) Otolaryngol Head Neck Surg. 2005 Feb;132(2):327-9. Facial palsy associated with acute otitis media. Popovtzer A1, Raveh E, Bahar G, Oestreicher-Kedem Y, Feinmesser R, Nageris BI.

14) Eur Arch Otorhinolaryngol. 2005 May;262(5):416-22. Epub 2004 Sep 18.

Endoscopy versus radiography for the diagnosis of acute bacterial rhinosinusitis. Berger G1, Steinberg DM, Popovtzer A, Ophir D

2006

1) J Surg Oncol. 2006 Jun 1;93(7):529-33. Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5-fluorouracil. Yerushalmi R1, Idelevich E, Dror Y, Stemmer SM, Figer A, Sulkes A, Brenner B, Loven D, Dreznik Z, Nudelman I, Shani A, Fenig E.

2) sr Med Assoc J. 2006 Sep;8(9):615-7.

Endobronchial stent for malignant airway obstructions. Yerushalmi R1, Fenig E, Shitrit D, Bendayan D, Sulkes A, Flex D, Kramer MR.

3) Clin Nucl Med. 2006 May;31(5):256-8.

Treatment of neuroblastoma using the fused imaging guided radiotherapy (FIGURA) system. Fenig E1, Mishaeli M, Yerushalmi R, Sever ZB, Ash S, Kornreich L, Yaniv I, Steinmetz A.

4) Surg Oncol. 2006 Jul;15(1):29-32. Epub 2006 Aug 14. Small bowel obstruction caused by secondary tumors. Idelevich E1, Kashtan H, Mavor E, Brenner B

5) J Surg Oncol. 2006 Jun 1;93(7):529-33. Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5-fluorouracil. Yerushalmi R1, Idelevich E, Dror Y, Stemmer SM, Figer A, Sulkes A, Brenner B, Loven D, Dreznik Z, Nudelman I, Shani A, Fenig E.

6) Anticancer Res. 2006 Nov-Dec;26(6B):4423-30.

Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity. Lev-Ari S1, Starr A, Vexler A, Karaush V, Loew V, Greif J, Fenig E, Aderka D, Ben-Yosef R.

7) Otolaryngol Head Neck Surg. 2006 Oct;135(4):581-4.

Thyroid cancer in children: management and outcome experience of a referral center. Popovtzer A1, Shpitzer T, Bahar G, Feinmesser R, Segal K

8) Otolaryngol Head Neck Surg. 2006 May;134(5):819-22. Invasive well-differentiated thyroid carcinoma: effect of treatment modalities on outcome. Segal K1, Shpitzer T, Hazan A, Bachar G, Marshak G, Popovtzer A

9) Curr Opin Otolaryngol Head Neck Surg. 2006 Apr;14(2):82-4.

Is there any significant reduction of patients' outcome following delay in commencing postoperative radiotherapy? Marshak G1, Popovtzer A

2007

1) J Clin Oncol. 2007 Jun 1;25(16):2212-7. Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer: a randomized, multicenter, phase III trial of the Swiss Group for Clinical Cancer Research and the Central European Cooperative Oncology Group. Herrmann R1, Bodoky G, Ruhstaller T, Glimelius B, Bajetta E, Schüller J, Saletti P, Bauer J, Figer A, Pestalozzi B, Köhne CH, Mingrone W, Stemmer SM, Tàmas K, Kornek GV, Koeberle D, Cina S, Bernhard J, Dietrich D, Scheithauer W; Swiss Group for Clinical Cancer Research; Central European Cooperative Oncology Group

2) Am J Clin Oncol. 2007 Aug;30(4):389-94. Adjuvant radiotherapy for thymic epithelial tumor: treatment results and prognostic factors. Kundel Y1, Yellin A, Popovtzer A, Pfeffer R, Symon Z, Simansky DA, Oberman B, Sadezki S, Brenner B, Catane R, Levitt ML.

3) Anticancer Drugs. 2007 Jul;18(6):733-5. Adjuvant chemotherapy with 5-fluorouracil in a patient with colorectal cancer and Familial Mediterranean Fever.

Purim O1, Sulkes A, Brenner B

4) Anticancer Res. 2007 Jul-Aug;27(4C):2877-80. A phase II study of oral UFT and leucovorin concurrently with pelvic irradiation as neoadjuvant chemoradiation for rectal cancer. Kundel Y1, Brenner B, Symon Z, Oberman B, Sadezki S, Koller M, Catane R, Pfeffer R

5) Semin Oncol. 2007 Feb;34(1):43-50. Small cell carcinomas of the gastrointestinal tract: clinicopathological features and treatment approach. Brenner B1, Tang LH, Shia J, Klimstra DS, Kelsen DP.

6) Eur J Pediatr. 2007 Jul;166(7):663-6. Epub 2006 Oct 11. Successful treatment of Wolman disease by unrelated umbilical cord blood transplantation. Stein J1, Garty BZ, Dror Y, Fenig E, Zeigler M, Yaniv I.

7) Cancer. 2007 Jan 1;109(1):54-9. Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile. Bahar G1, Feinmesser R, Shpitzer T, Popovtzer A, Nagler RM

8) Head Neck. 2007 Jun;29(6):559-63.

Cyclooxygenase-2 expression in medullary thyroid carcinoma. Popovtzer A1, Morgenstein S, Roizman P, Gutman D, Bahar G, Stern Y, Feinmesser R.

2008

1) J Clin Oncol. 2008 Aug 1;26(22):3695-701. doi: 10.1200/JCO.2007.15.6240. Clinical benefit and quality of life in patients with advanced pancreatic cancer receiving gemcitabine plus capecitabine versus gemcitabine alone: a randomized multicenter phase III clinical trial--SAKK 44/00-CECOG/PAN.1.3.001.

Bernhard J1, Dietrich D, Scheithauer W, Gerber D, Bodoky G, Ruhstaller T, Glimelius B, Bajetta E, Schüller J, Saletti P, Bauer J, Figer A, Pestalozzi BC, Köhne CH, Mingrone W, Stemmer SM, Tàmas K, Kornek GV, Koeberle D, Herrmann R; Central European Cooperative Oncology Group.

2) Int J Oncol. 2008 Aug;33(2):287-95.

The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways. Bar-Yehuda S1, Stemmer SM, Madi L, Castel D, Ochaion A, Cohen S, Barer F, Zabutti A, Perez-Liz G, Del Valle L, Fishman P.

3) J Clin Oncol. 2008 May 10;26(14):2396-404. doi: 10.1200/JCO.2007.15.5796. Interventions for alleviating cancer-related dyspnea: a systematic review. Ben-Aharon I1, Gafter-Gvili A, Paul M, Leibovici L, Stemmer SM.

4) Clin Infect Dis. 2008 Jun 15;46(12):1859-63. doi: 10.1086/588290.

The influence of mucositis on oral thermometry: when fever may not reflect infection. Ciuraru NB1, Braunstein R, Sulkes A, Stemmer SM.

5) Med Sci Monit. 2008 Apr;14(4):CR190-5.

Weekly infusional high-dose 5-fluorouracil and leucovorin and biweekly cisplatin: a convenient treatment option in advanced gastric cancer. Kundel Y1, Purim O, Figer A, Stemmer SM, Tichler T, Sulkes J, Sulkes A, Brenner B.

6) Lupus. 2008 Mar;17(3):206-9. doi: 10.1177/0961203307086235. Severe digital ischemia-a presenting symptom of malignancy-associated antiphospholipid syndrome. Grossman A1, Gafter-Gvili A, Green H, Ben Aharon I, Stemmer SM, Molad Y, Krause I.

7) Oncol Rep. 2008 Dec;20(6):1533-8. Concurrent chemobiotherapy with cisplatin, dacarbazine, decrescendo interleukin-2 and interferon alpha2b in patients with metastatic melanoma. Bar J1, Yerushalmi R, Shapira-Frummer R, Kutchuk I, Sulkes A, Gutman H, Catane R, Schachter J

8) Lancet. 2008 Jan 5;371(9606):4-5. doi: 10.1016/S0140-6736(08)60043-4.

Chemotherapy for oestrogen-receptor-negative breast cancer. Yerushalmi R1, Gelmon K.

9) Acta Oncol. 2008;47(1):104-9.

Daily low-dose/continuous capecitabine combined with neo-adjuvant irradiation reduces VEGF and PDGF-BB levels in rectal carcinoma patients.

Loven D1, Be'ery E, Yerushalmi R, Koren C, Sulkes A, Lavi I, Shaked Y, Fenig E

10) Onkologie. 2008 Dec;31(12):673-7. doi: 10.1159/000165056. Epub 2008 Nov 14. Overall survival with cisplatin and 5-fluorouracil neoadjuvant treatment in patients with esophageal cancer: single-center experience. Idelevich E1, Buyevich V, Machlenkin S, Ziv-Sokolovsky N, Dinerman M, Brenner B, Kashtan H

11) Tumori. 2008 Jul-Aug;94(4):469-73. Adjuvant chemotherapy and whole abdominal irradiation for gastric carcinoma. Kundel Y1, Levitt ML, Oberman B, Sadezki S, Tichler T, Symon Z, Catane R, Pfeffer R, Brenner B.

12) Appl Immunohistochem Mol Morphol. 2008 Oct;16(5):442-6. doi: 10.1097/PAI.0b013e31815f982a. Cyclooxygenase-2 expression in primary and metastatic Merkel cell carcinoma. Joachims Z1, Feinmesser R, Purim O, Halpern M, Brenner B, Fenig E, Roizman P, Sulkes J, Feinmesser M

13) Med Sci Monit. 2008 Apr;14(4):CR190-5. Weekly infusional high-dose 5-fluorouracil and leucovorin and biweekly cisplatin: a convenient treatment option in advanced gastric cancer. Kundel Y1, Purim O, Figer A, Stemmer SM, Tichler T, Sulkes J, Sulkes A, Brenner B.

14) Am J Surg Pathol. 2008 May;32(5):719-31. doi: 10.1097/PAS.0b013e318159371c.

Is nonsmall cell type high-grade neuroendocrine carcinoma of the tubular gastrointestinal tract a distinct disease entity? Shia J1, Tang LH, Weiser MR, Brenner B, Adsay NV, Stelow EB, Saltz LB, Qin J, Landmann R, Leonard GD, Dhall D, Temple L, Guillem JG, Paty PB, Kelsen D, Wong WD, Klimstra DS

15) Nano Lett. 2008 Dec;8(12):4593-6. Targeted gold nanoparticles enable molecular CT imaging of cancer. Popovtzer R1, Agrawal A, Kotov NA, Popovtzer A, Balter J, Carey TE, Kopelman R

16) nt J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1287-90. doi:

10.1016/j.ijrobp.2008.08.024. Early prediction of outcome in advanced head-and-neck cancer based on tumor blood volume alterations during therapy: a prospective study. Cao Y1, Popovtzer A, Li D, Chepeha DB, Moyer JS, Prince ME, Worden F, Teknos T, Bradford C, Mukherji SK, Eisbruch A.

17) Nanomedicine. 2008 Jun;4(2):121-6. doi: 10.1016/j.nano.2008.03.002. Epub 2008 May 14. Electrochemical lab on a chip for high-throughput analysis of anticancer drugs efficiency. Popovtzer R1, Neufeld T, Popovtzer A, Rivkin I, Margalit R, Engel D, Nudelman A, Rephaeli A, Rishpon J, Shacham-Diamand Y.

18) xpert Rev Anticancer Ther. 2008 Apr;8(4):633-44. doi: 10.1586/14737140.8.4.633.

Advances in radiation therapy of head and neck cancer. Popovtzer A1, Eisbruch A.

2009

1) Ann Oncol. 2009 Mar;20(3):437-40. doi: 10.1093/annonc/mdn652. Epub 2009 Jan 12.

Decline in pulmonary function in patients with breast cancer receiving dose-dense chemotherapy: a prospective study. Yerushalmi R1, Kramer MR, Rizel S, Sulkes A, Gelmon K, Granot T, Neiman V, Stemmer SM

2) Breast Cancer Res Treat. 2010 Apr;120(3):753-9. doi: 10.1007/s10549-009-0510-2. Epub 2009 Aug 22.

Patterns of relapse in breast cancer: changes over time. Yerushalmi R1, Woods R, Kennecke H, Speers C, Knowling M, Gelmon K

3) Clin Breast Cancer. 2009 Aug;9(3):166-72. doi: 10.3816/CBC.2009.n.027. A phase II trial of a neoadjuvant platinum regimen for locally advanced breast cancer: pathologic response, long-term follow-up, and correlation with biomarkers. Yerushalmi R1, Hayes MM, Gelmon KA, Chia S, Bajdik C, Norris B, Speers C, Hassell P, O'Reilly SE, Allan S, Shenkier TN.

4) Breast Cancer Res Treat. 2009 Sep;117(2):365-70. doi: 10.1007/s10549-008-0265-1. Epub 2008 Dec 11.

Does multicentric/multifocal breast cancer differ from unifocal breast cancer? An analysis of survival and contralateral breast cancer incidence. Yerushalmi R1, Kennecke H, Woods R, Olivotto IA, Speers C, Gelmon KA

5) J Am Coll Surg. 2009 Feb;208(2):173-8. doi: 10.1016/j.jamcollsurg.2008.10.022. Epub 2008 Dec 18.

Endoscopic ultrasound can improve the selection for laparoscopy in patients with localized gastric cancer. Power DG1, Schattner MA, Gerdes H, Brenner B, Markowitz AJ, Capanu M, Coit DG, Brennan M, Kelsen DP, Shah MA

6) Chemotherapy. 2009;55(2):76-82. doi: 10.1159/000183732. Epub 2008 Dec 12. Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer. Idelevich E1, Greif F, Mavor E, Miller R, Kashtan H, Susmalian S, Ariche A, Brenner B, Baruch NB, Dinerman M, Shani A

7) Psychooncology. 2009 Aug;18(8):866-74. doi: 10.1002/pon.1499. How relevant is marital status and gender variables in coping with colorectal cancer? A sample of middle-aged and older cancer survivors. Goldzweig G1, Andritsch E, Hubert A, Walach N, Perry S, Brenner B, Baider L.

8) Crit Rev Oncol Hematol. 2009 Apr;70(1):71-82. doi: 10.1016/j.critrevonc.2008.07.014. Epub 2008 Aug 30.

Gender and psychological distress among middle- and older-aged colorectal cancer patients and their spouses: an unexpected outcome. Goldzweig G1, Hubert A, Walach N, Brenner B, Perry S, Andritsch E, Baider L

9) Rev Invest Clin. 2009 Mar-Apr;61(2):181; author reply 182. [Comments to the manuscript: Survival after radical prostatectomy in patient with prostate cancer and seminal vesicle invasion]. [Article in Spanish] Sulkes A

10) Clin Cancer Res. 2009 Feb 1;15(3):914-23. doi: 10.1158/1078-0432.CCR-08-0792. Ionizing radiation up-regulates telomerase activity in cancer cell lines by post-translational mechanism via ras/phosphatidylinositol 3-kinase/Akt pathway. Ram R1, Uziel O, Eldan O, Fenig E, Beery E, Lichtenberg S, Nordenberg Y, Lahav M

11) Radiother Oncol. 2009 Dec;93(3):510-5. doi: 10.1016/j.radonc.2009.05.013. Epub

2009 Jun 10. Anatomical changes in the pharyngeal constrictors after chemo-irradiation of head and neck cancer and their dose-effect relationships: MRI-based study. Popovtzer A1, Cao Y, Feng FY, Eisbruch A.

12) Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1342-7. doi: 10.1016/j.ijrobp.2008.10.042. Epub 2009 Jan 8.

The pattern of failure after reirradiation of recurrent squamous cell head and neck cancer: implications for defining the targets. Popovtzer A1, Gluck I, Chepeha DB, Teknos TN, Moyer JS, Prince ME, Bradford CR, Eisbruch A.

13) Int J Radiat Oncol Biol Phys. 2009 May 1;74(1):38-46. doi: 10.1016/j.ijrobp.2008.06.1943. Epub 2008 Oct 19.

Skin cancer of the head and neck with perineural invasion: defining the clinical target volumes based on the pattern of failure. Gluck I1, Ibrahim M, Popovtzer A, Teknos TN, Chepeha DB, Prince ME, Moyer JS, Bradford CR, Eisbruch A

2010-2011

1) Bar-Joseph H, Ben-Aharon I, Rizel S, Stemmer SM, Tzabari M and Shalgi R Doxorubicin-

induced apoptosis in germinal vesicle oocytes. Reproductive Toxicology 2010; 30:566-572.

2) Ben-Aharon, I, Bar-Joseph, H., Tzarfaty, G., Stemmer, S.M., Kuchinsky, L., Rizel, S and Shalgi, R. "Doxorubicin-induced ovarian toxicity". Reprod Biol Endocrinol 2010; 4:8-20.

3) Ben-Aharon I, Gafter-Gvili A, Leibovici L and Stemmer SM. "Pharmacological interventions for fertility preservation during chemotherapy – a systematic review and meta-analysis". Breast Cancer Res Treat. 2010; 122:803-11.

4) Bonilla L, Ben-Aharon I, Vidal L, Gafter-Gvili A, Leibovici L and Stemmer SM. "The role of dose dense adjuvant chemotherapy in breast cancer treatment; a systematic review and meta-analysis". J Natl Cancer Inst, 2010; 142:1845-1854.

5) Bar-Joseph H, Ben-Aharon I, Tsarfaty G, Tzabari M, Stemmer SM, and Shalgi R "Novel in

vivo imaging of acute chemotherapy-induced vascular toxicity". Accepted for PLoS One

6) D. Hendler and S. Stemmer. Uncommon reason for High Fluorodeoxyglucose Positron

Emission Tomography Uptake.

J Clin Oncol 2010; 28: 659-660

7) D. Hendler, S. Rizel, R. Yerushalmi, V. Neiman, L. Bonilla, R. Braunstein, A. Sulkes, S.

Stemmer. Different Schedules of Granulocyte Growth Factor Support for Patients with Breast Cancer Receiving Adjuvant Dose-Dense Chemotherapy.

Am J Clin Oncol 2011; 34:619-624

8) Wein S, Pery S, Zer A. The Role of Palliative Care in Adolescent and Young Adult

Oncology. Journal of Clinical Oncology, 28:4819-4824, 2010

9) Wein S. The Transformation of Tragedy. Journal of Palliative Medicine 13:493-494, 2010

10) Wein S. A View of Life in Death, Journal of Palliative Care, 26:3, 205-206, 2010

11) Wein S. Blaming the messenger and not the message. Palliative & Supportive Care

8:235, 2010

12) Wein S. A Fight to the End, or an End to the Fight - editorial. Palliative & Supportive

Care 8:391-393, 2010

13) Wein S, Sulkes A, Stemmer S. The Oncologists’ Role in Managing Depression, Anxiety and Demoralization in Advanced Cancer.Cancer J. 2010, 16:493-9.

14) Wein S. Impact of Culture on the Expression of Pain and Suffering. J Pediatr Hematol Oncol, 2011 (in press)

15) Is local excision after complete pathological response to neoadjuvant chemoradiation

for rectal cancer an acceptable treatment option?

Kundel Y, Brenner R, Purim O, Peled N, Idelevich E, Fenig E, Sulkes A, Brenner B.

Dis Colon Rectum. 2010; 53: 1624-31.

16) Gastric cancer: Biology and clinical manifestations in Israel.

Dreznik A, Purim O, Idelevich E, Kundel Y, Sulkes J, Sulkes A, Brenner B.

J Surg Oncol. 2011 Aug 31. doi: 10.1002/jso.22078. [Epub ahead of print]

17) ImMucin: a novel therapeutic vaccine with promiscuous MHC binding for the treatment

of MUC1-expressing tumors.

Kovjazin R, Volovitz I, Kundel Y, Rosenbaum E, Medalia G, Horn G, Smorodinsky NI, Brenner B, Carmon L.

Vaccine. 2011;29:4676-86.

18) Amitay-Laish I, David M, Stemmer SM. Staphylococcus coagulase-positive skin

inflammation associated with epidermal growth factor receptor-targeted therapy: an early and a late phase of papulopustular eruptions.

Oncologist. 2010;15:1002-8. Epub 2010 Aug 13

19) Cohen S, Stemmer S, Zozulya G, Ochaion A, Patoka R, Barer F, Bar-Yehuda S, L,

Jacobson K, Fishman P. CF102 an A (3) adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver.

J Cell Physiol. 2011 Sep;226:2438-47. doi:10.1002/jcp. 22593

20) Saad F, Brown JE, Van Poznak C, Ibrahim T, Stemmer SM, Stopeck AT, Diel IJ, Takahashi

S, Shore N, Henry DH, Barrios CH, Facon T, Senecal F, Fizazi K, Zhou L, Daniels A, Carrière P, Dansey R. Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. Ann Oncol. 2011, Oct 10. [Epub ahead of print]

21) Safra T, Bernstein-Molho R, Greenberg J, Pelles-Avraham S, Stephansky I, Sarid D, Inbar MJ, Stemmer SM*, and Geffen DB* (*equal contribution) Effect of Zoledronic Acid on Bone Loss in Postmenopausal Women With Early Breast Cancer Treated with Sequential Tamoxifen and Letrozole: A Prospective, Randomized, Phase II Trial.

Oncology. 2011 Dec 8;81:298-305. [Epub ahead of print]

22) A. Sulkes

Novel multitargeted oral therapies:

Sunitinib and Sorafenib as a paradigm

Isr Med Assoc J 12:628-632, 2010

2012

(N = 28) 2012 –Publications A. Dreznik, O. Purim, E. Idelevich, Y. Kundel, J. Sulkes, A. Sulkes, B. Brenner.

Gastric cancer: Biology and clinical manifestations in Israel

322, 2012.-, 105:316J Surg Oncol

A. Weissmann-Brenner, M. Kushnir, G. Lithwick-Yanai, R. Aharonov, H. Gibori, O. Purim, Y. Kundel, S. Morgenstern, M. Halperin, Y. Niv, B. Brenner.

Tumor microRNA-29a expression and the risk of recurrence in stage II colon cancer.

03, 2012.21-40:2097 Int J Oncol.

N. Goldberg, Y. Kundel, O. Purim, H. Bernstine, N. Gordon, S. Morgenstern, E. Idelevich, N. Wasserberg, A. Sulkes, D. Groshar, B. Brenner. Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18F-FDG PET-CT imaging.

7:124, 2012. Radiat Oncol.

E. Idelevich, H. Kashtan, Y. Klein, V. Buevich, N. Ben-Baruch, M. Dinerman, M. Toker, Y. Kundel, B. Brenner.

Prospective phase II study of neoadjuvant therapy with cisplatin, 5-fluorouracil, and bevacizumab for locally advanced resectable esophageal cancer.

431, 2012.-. 35:427Onkologie

L. Rath-Wolfson, O. Purim, E. Ram, S. Morgenstern, R. Koren, B. Brenner.

Expression of estrogen receptor B1 in colorectal cancer: correlation with clinicopathological variables.

2022, 2012-. 27:2017Oncol Rep

Yerushalmi R, Tyldesley S, Kennecke H, Speers Caroline, Woods Ryan, Knight Brian, Gelmon of elevation and Karen. Tumor markers in metastatic breast cancer subtypes:frequency

45, 2012 (6.425)-23: 338 Ann Oncolcorrelation with outcome.

Yerushalmi R, Gelmon KA, Leung S, Gao D, Cheang M, Pollack M, Turashvili G, Gilks BC, Kennecke H. Insulin like growth factor (IGF-1R) in breast cancer subtypes

42, 2012. -132: 131 es and TreatBreast Cancer R

(ONCOLOGY 36/194, IF 4.431)

Yerushalmi R, Tyldesley S, Woods R, Kennecke HF, Speers C, Gelmon KA. Is breast-conserving Ann therapy a safe option for patients with tumor multicentricity and multifocality?

81, 2012.-623: 87 Oncol

(ONCOLOGY 17/194, IF 6.425)

Yerushalmi R, Sulkes A. Adjuvant treatment with Trastuzumab in early breast cancer, Harefuah, 151:34-36, 2012.

Ben-Aharon I, Gafter-Gvili A, Leibovici L and Stemmer SM

“Interventions to alleviate cancer related dyspnea – a systematic review and meta-analysis”

3.32 (60/185).-IF 1008.-2012 51:996 Acta Oncologica

Ben-Aharon I, Meizner I, Granot T, Rizel S, Yerushalmi R, Sulkes A, and Stemmer SM.

"Chemotherapy-induced ovarian vascular toxicity in young breast cancer patients"

3.82 (52/185) –sept 2012 IF The Oncologist

Zer A, Rizel S, Braunstein R, Yerushalmi R, Hendler D, Neimann V, Cioreuru N, Sulkes A, Stemmer SM. Tailoring Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer:

A Historical Prospective Study.

101.-2012; 58:95 Chemotherapy

Saad F, Brown JE, Van Poznak C, Ibrahim T, Stemmer SM, Stopeck AT, Diel IJ, Takahashi S, Shore N, Henry DH, Barrios CH, Facon T, Senecal F, Fizazi K, Zhou L, Daniels A, Carrier P, Dansey R.

Incidence, Risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases.

7.-2012 May; 23: 1341 Ann Oncol

(ONCOLOGY 52/196, IF 3.812)

Hamama-Raz Y, Perry S, Pat-Horenczyk R, Bar-Levav R, Stemmer SM, Factors affecting participation in group intervention in patients after adjuvant treatment for early-stage breast cancer.

14-2012 Feb; 51: 208Acta Oncologica

(ONCOLOGY 67/196, IF 3.330)

Lang I, Inbar MJ, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Messinger D, Brodowicz T, Zielinski C.

Safety results from a phase III study (TURANDOT trial by CECOG) of first-line bevacizumab in combination with capecitabine or paclitaxel for HER-2-negative locally recurrent or metastatic breast cancer.

9.-2012; 48: 3140Eur J Cancer

(ONCOLOGY 26/196, IF 5.536

PalliativeSulkes A, Wein S. Mexico: the lively colors of death. &Supportive Care ,2012;10(1:)65-66

Wein S .Heroism and the Fear of Death ,2-, 2012;15(7):731Journal of Palliative Medicine

, Paineuropeinduced constipation in palliative care, -: Issue 2012 Wein S. Opioid9,2-8

Wein S .Between solitude and loneliness – a meditation .Editorial .Palliative and

Supportive Care ,2012,10(2:)3-71

Wein S .Vignettes from a zone of conflict ,Palliative and Supportive Care.

2012;10(4:)305-6

. 2012;15(9):1041Journal of Palliative MedicineWein S. Three Love Stories,

PalliativeWein S. Suicidality, and Supportive Care. 2012;10(3:)30-229

2012 ASCO Wein S. The Oncologist's Duty to Provide Hope: Fact or Fiction? In: Govindan R, ed. . Alexandria, VA: American Society of Clinical Oncology; 2012Educational Book

,uropePainerelated pain and constipation.-Wein S. Management of cancer

2012:Issue 3, 10-11

2-, 2012;30(25):3141JCOWein S, Baider L. Blindness: Looking but Not Seeing.

Nahshoni E, Golobchik P, Glazer J, Sever J, Strasberg B, Imbar S, Shoval G, Weizman A and Zalsman G. Late potentials in the signal-averaged electrocardiogram in pre-pubertal children with ADHD before and after methylphenidate treatment.

78.-21:752012; European Child and Adolescent Psychiatry,

Freudenstein O, Valevski A, Apter A, Zohar A, Shoval G, Nahshoni E, Weizman A, Zalsman G.

Perfectionism, Narcissism and Depression in Suicidal and Non-Suicidal Adolescent Inpatients.

52.-53:746 2012; Comprehensive Psychiatry,

Shoval G, Manor I, Nahshoni E, Weizman A, Zalsman G.

ames of Children with Attention Deficit Hyperactivity Disorder More 'Hyperactive'?Are N

219.-45:215 2012; Psychopathology,

2013

1.Clinical effectiveness of seasonal influenza vaccine among adult cancer patients.Vinograd I, Eliakim-Raz N, Farbman L, Baslo R, Taha A, Sakhnini A, Lador A, Stemmer SM, Gafter-Gvili A, Leibovici L, Paul M.Cancer. 2013 Sep 16. doi: 10.1002/cncr.28351. [Epub ahead of print]PMID: 24105033 [PubMed - as supplied by publisher]Related citations

2.Doxorubicin-induced vascular toxicity--targeting potential pathways may reduce procoagulant activity.Ben Aharon I, Bar Joseph H, Tzabari M, Shenkman B, Farzam N, Levi M, Shalgi R, Stemmer SM, Savion N.PLoS One. 2013 Sep 20;8(9):e75157. doi: 10.1371/journal.pone.0075157.PMID: 24073244 [PubMed - in process] Free PMC Article Related citations

3.Bisphosphonates in the adjuvant setting of breast cancer therapy--effect on survival: a systematic review and meta-analysis.Ben-Aharon I, Vidal L, Rizel S, Yerushalmi R, Shpilberg O, Sulkes A, Stemmer SM.PLoS One. 2013 Aug 26;8(8):e70044. doi:

10.1371/journal.pone.0070044.PMID: 23990894 [PubMed - in process] Free PMC Article Related citations

4.Phase II study of concurrent capecitabine and external beam radiotherapy for pain control of bone metastases of breast cancer origin.Kundel Y, Nasser NJ, Purim O, Yerushalmi R, Fenig E, Pfeffer RM, Stemmer SM, Rizel S, Symon Z, Kaufman B, Sulkes A, Brenner B.PLoS One. 2013 Jul 10;8(7):e68327. doi: 10.1371/journal.pone.0068327. Print 2013.PMID: 23874586 [PubMed - in process] Free PMC Article Related citations

5.The impact of the 21-gene Recurrence Score assay on clinical decision-making in node-positive (up to 3 positive nodes) estrogen receptor-positive breast cancer patients.Stemmer SM, Klang SH, Ben-Baruch N, Geffen DB, Steiner M, Soussan-Gutman L, Merling S, Svedman C, Rizel S, Lieberman N.Breast Cancer Res Treat. 2013 Jul;140(1):83-92. doi: 10.1007/s10549-013-2603-1. Epub 2013 Jun 26.PMID: 23801158 [PubMed - in process] Free PMC Article Related citations

6.Randomized phase II study of the anti-epidermal growth factor receptor monoclonal antibody cetuximab with cisplatin versus cisplatin alone in patients with metastatic triple-negative breast cancer.Baselga J, Gómez P, Greil R, Braga S, Climent MA, Wardley AM, Kaufman B, Stemmer SM, Pêgo A, Chan A, Goeminne JC, Graas MP, Kennedy MJ, Ciruelos Gil EM, Schneeweiss A, Zubel A, Groos J, Melezínková H, Awada A.J Clin Oncol. 2013 Jul 10;31(20):2586-92. doi: 10.1200/JCO.2012.46.2408. Epub 2013 Jun 3.PMID: 23733761 [PubMed - indexed for MEDLINE]Related citations

7.Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for HER2-negative metastatic breast cancer: interim efficacy results of the randomised, open-label, non-inferiority, phase 3 TURANDOT trial.Lang I, Brodowicz T, Ryvo L, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Melichar B, Pienkowski T, Sirbu D, Messinger D, Zielinski C; Central European Cooperative Oncology Group.Lancet Oncol. 2013 Feb;14(2):125-33. doi: 10.1016/S1470-2045(12)70566-1. Epub 2013 Jan 10.PMID: 23312888 [PubMed - indexed for MEDLINE]Related citations

8.CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label, dose-escalation study.Stemmer SM, Benjaminov O, Medalia G, Ciuraru NB, Silverman MH, Bar-Yehuda S, Fishman S, Harpaz Z, Farbstein M, Cohen S, Patoka R, Singer B, Kerns WD, Fishman P.Oncologist. 2013;18(1):25-6. doi: 10.1634/theoncologist.2012-0211.

Epub 2013 Jan 8.PMID: 23299770 [PubMed - indexed for MEDLINE] Free PMC Article Related citations

9.A randomized and open-label trial evaluating the addition of pazopanib to lapatinib as first-line therapy in patients with HER2-positive advanced breast cancer.Johnston SR, Gómez H, Stemmer SM, Richie M, Durante M, Pandite L, Goodman V, Slamon D.Breast Cancer Res Treat. 2013 Feb;137(3):755-66. doi: 10.1007/s10549-012-2399-4. Epub 2013 Jan 3.PMID: 23283526 [PubMed - indexed for MEDLINE]Related citations

10. Ben-Aharon I and Sulkes A “Cancer metastases – who is the seed of evil? “

Harefuah 2013 152(1):26-7, 59

11. Amit L, Ben-Aharon I, Vidal L, Leibovic L, Stemmer SM. “The impact of Bevacizumab (Avastin) on survival in metastatic solid tumors- A meta-analysis and systematic review”

PLoS One 2013;8(7). doi: 10.1371

12 . Wein S .Ten things a ward consultant should never ( ever )do .Med J Aust. 2013; 198 (1): 51

13. Wein S. Limitations of the Intellect in Matters Concerning Life and Death. The Oncologist 2013;18 (2), pp. e6

14. Wein S. The sex of cancer: Ongoing lessons of cultural diversity. Palliative and Supportive Care, 2013;12, 1-3

Spruyt O, Westerman D, Milner A, Bressel M, Wein S. A randomised, double-blind, placebo-controlled study to assess the safety and efficacy of methoxyflurane for procedural pain of a bone marrow biopsy. BMJ Support Palliat Care 2013, June (On-Line First)

15. Wein S. Ignorance or knowledge. Editorial. Palliative & Supportive Care, 2013;11,1-2

16.Do alternative methods of measuring tumor size, including consideration of multicentric/multifocal disease, enhance prognostic information beyond TNM staging in women with early stage breast cancer: an analysis of the NCIC CTG MA.5 and MA.12 clinical trials.

Hilton JF, Bouganim N, Dong B, Chapman JW, Arnaout A, O'Malley F, Gelmon KA, Yerushalmi R, Levine MN, Bramwell VH, Whelan TJ, Pritchard KI, Shepherd LE, Clemons M.

Breast Cancer Res Treat. 2013 Nov;142(1):143-51. doi: 10.1007/s10549-013-2714-8. Epub 2013 Oct 11.

PMID: 24113743 [PubMed - in process]

Select item 239908944.

17.Breast cancer and leptomeningeal disease (LMD): hormone receptor status influences time to development of LMD and survival from LMD diagnosis.

Yust-Katz S, Garciarena P, Liu D, Yuan Y, Ibrahim N, Yerushalmi R, Penas-Prado M, Groves MD.

J Neurooncol. 2013 Sep;114(2):229-35. doi: 10.1007/s11060-013-1175-6. Epub 2013 Jun 12.

PMID: 23756727 [PubMed - in process]

18. R.M. Brenner, S. Kivity, Y. Kundel, O. Purim, N. Peled, E. Idelevich, K. Lavrenkov, S. Kovel, E. Fenig, A. Sulkes, B. Brenner.

Ethnic variation in toxicity and outcome of adjuvant chemoradiation for gastric cancer in Israel.

Anticancer Res. 33:5151-5157, 2013.

19. O. Purim, N. Gordon, B. Brenner.

Cancer of the colon and rectum: potential effects of sex-age interactions on incidence and outcome.

Med. Sci Monit. 19:203-209, 2013.

20. Hyperbaric oxygen therapy for hemorrhagic radiation cystitis.

Shilo Y, Efrati S, Simon Z, Sella A, Gez E, Fenig E, Wygoda M, Lindner A, Fishlev G, Stav K, Zisman A, Siegel YI, Leibovici D.

Isr Med Assoc J. 2013;15:75-8.

2014 1) The 21-gene recurrence score assay (Oncotype DX™) in estrogen receptor-positive male breast cancer: experience in an Israeli cohort. Grenader T, Yerushalmi R, Tokar M, Fried G, Kaufman B, Peretz T, Geffen DB. Oncology. 2014;87(1):1-6. 2) Personalized prostate cancer screening among men with high risk genetic predisposition- study protocol for a prospective cohort study. Margel D, Benjaminov O, Ozalvo R, Shavit Grievink L, Kedar I, Yerushalmi R, Ben-Aharon I, Neiman V, Yossepowitch O, Kedar D, Levy Z, Shohat M, Brenner B, Baniel J, Rosenbaum E. BMC Cancer. 2014 Jul 21;14:528

3) Adjuvant docetaxel and cyclophosphamide (DC) with prophylactic granulocyte colony-stimulating factor (G-CSF) on days 8 &12 in breast cancer patients: a retrospective analysis. Rinat Yerushalmi, Hadar Goldvaser, Aaron Sulkes, Irit Ben-Aharon, Daniel Hendler, Victoria Neiman, Noa Beatrice Ciuraru, Luisa Bonilla, Limor Amit, Alona Zer, Tal Granot , Shulamith Rizel, and Salomon M. Stemmer. PLoS One. 2014 Oct 15;9(10):e107273. doi: 10.1371/journal.pone.0107273. eCollection 2014. 4) Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells. Raiter A*, Yerushalmi R*, Hardy B. Oncotarget. 2014, 5(22):11452-63

*Equal contribution

5) Britta Hardy Cell surface GRP78: a good prognosis and a potential marker of response to chemotherapy in breast cancer. Rinat Yerushalmi *, Annat Raiter *, Karen Nalbandyan, *Equal contribution. Oncology Letters- in press

6) Conflicting pathological reports: A diagnostic dilemma. Shahar T, Rozovski U, Shapira Y, Nossek E, Zelikovich B, Jossiphov J, Ram Z, Kanner AA, Siegal T, Blumenthal DT, Lavon I. J. Neurosurgery Nov 25:1-4, 2014

7) Primary CNS Lymphoma: Current State of anti CD20 therapy and appraisal of reported response Siegal T. criteria. J. Clin. Neurosciences 21(5):709-715, 2014

8) A 66 year old man with progressive left hemiparesis

Lotan I, Djaldetti R, Luckman J, Siegal T, Steiner I.. J. Clin. Neurosciences 21(11):1966;2031, Nov.2014

9) Antineoplastic Effect of Decoy Oligonucleotide Derived From MGMT Enhancer.(equal contribution of last two authors). Canello T, Ovadia H, Refael M, Zrihan D, Siegal T*., lavon I*. PLoS1 9(12):e113854, 2014

10) Clinical impact of molecular biomarkers in gliomas. Journal of Clinical Neurosiences. Siegal T

E-pub Dec 2014

11) Chemotherapy and/or targeted therapies for advanced endometrial cancer: Time to Rethink. In: Controversies in the Management of Gynecological Cancers. Erica Stringer, Daliah Tsoref, Gini Fleming, Amit Oza. (2014). Ledermann J.A. Springer publications. 12) Aspirin in prevention of ovarian cancer: Are we at the tipping point? Daliah Tsoref, Tony Panzarella, Amit Oza

Editorial. Journal National Cancer Institute doi:10.1093/jnci/djt453(2014). 13) Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer. A trial of the NCIC Clinical trials group (NCIC CTG IND-192) Daliah Tsoref, Stephen Welch, Susie Lau et al. Gynecologic Oncology (2014) 14) Impaired Sleep Quality in Crohn's Disease Depends on Disease Activity. Gingold-Belfer R, Peled N, Levy S, Katz N, Niv Y, Fass R, Fraser G, Dickman R. Digestive Disease Science, 59(1):146-151, 2014. (PMID: 24114045;). 15) Screening for lung cancer: time for large-scale screening by chest computed tomography. Shlomi Dekel, Ben-Avi Roni, Balmor G Ronen, Onn Amir, Peled Nir. European Respiratory Journal 44(1):217-38, 2014. (PMID: 24525442; IF: 6.355) 16) EGFR mutation testing practice in advanced non-small cell lung cancer. Jair Bar, Flex Dov, Hadas Sorotsky, Haim Biran, Julia Dudnik, Nili Peylan-Ramu, Nir Peled, Hovav, Maya Gips, Rivka Katsnelson, Shoshana Keren Rosenberg, Ofer Merimsky, Maya Gottfried. Lung, 192(5):759-63, 2014. (PMID: 24964874; IF ) 17) Serum Thymidine kinase 1 activity in diagnosis, prognosis and monitoring chemotherapy in lung cancer patients. B. Nisman, H. Nechushtan, H. Biran, H. Gantz-Sorotsky, N. Peled, S. Gronowitz, T. Peretz. Journal of Thoracic Oncology, 9(10):1668-72, 2014. (PMID: 25521401 ; RESPIRATORY SYSTEM 5/43; IF:5.8). 18) Unique Volatolomic Signatures of TP53 and KRAS in Lung Cells. Michael Davies, Orna Barash, Raneen Jeries, Nir Peled, Maya Ilouze, Russell Hyde, Michael Marcus, John Field, and Hossam Haick. British Journal of Cancer, 111(6):1213-21, 2014. (PMID: 25051409; IF: 5.21). 19) Mitochondrial induction as a potential radio-sensitizer in lung cancer cells - a short report. Ronen Shavit, Maya Ilouze, Tali Feinberg, Yaacov Richard Lawrence, Yossi Tzur, Nir Peled. Cell Oncol (Dordr). Jan 7, 2015. (PMID: 25563585 ; PATOLOGY 17/79.; IF: 3.105) 20) The CT halo sign in invasive aspergillosis. Shroff S, Shroff GS, Yust-Katz S, Olar A, Tummala S, Tremont-Lukats IW. Clin Case Rep. 2014 Jun;2(3):113-4. doi: 10.1002/ccr3.67. Epub 2014 Apr 28

21) Leptomeningeal dissemination in glioblastoma; an inspection of risk factors, treatment, and outcomes at a single institution. Mandel JJ, Yust-Katz S, Cachia D, Wu J, Liu D, de Groot JF, Yung AW, Gilbert MR. J Neurooncol. 2014 Dec;120(3):597-605. doi: 10.1007/s11060-014-1592-1. Epub 2014 Aug 29. 22) Prolonged survival in adult neurofibromatosis type I patients with recurrent high-grade gliomas treated with bevacizumab. Theeler BJ, Ellezam B, Yust-Katz S, Slopis JM, Loghin ME, de Groot JF. J Neurol. 2014 Aug;261(8):1559-64. doi: 10.1007/s00415-014-7292-0. Epub 2014 May 25. 23) Pregnancy and glial brain tumors. Yust-Katz S, de Groot JF, Liu D, Wu J, Yuan Y, Anderson MD, Conrad CA, Milbourne A, Gilbert MR, Armstrong TS. Neuro Oncol. 2014 Sep;16(9):1289-94. doi: 10.1093/neuonc/nou019. Epub 2014 Mar 9. 24) Molecular subtypes of glioblastoma are relevant to lower grade glioma. Guan X, Vengoechea J, Zheng S, Sloan AE, Chen Y, Brat DJ, O'Neill BP, de Groot J, Yust-Katz S, Yung WK, Cohen ML, Aldape KD, Rosenfeld S, Verhaak RG, Barnholtz-Sloan JS. PLoS One. 2014 Mar 10;9(3):e91216. doi: 10.1371/journal.pone.0091216. eCollection 2014. 25) Clinical and prognostic features of adult patients with gangliogliomas. Yust-Katz S, Anderson MD, Liu D, Wu J, Yuan Y, Olar A, Fuller GN, Brown PD, de-Groot JF. Neuro Oncol. 2014 Mar;16(3):409-13. doi: 10.1093/neuonc/not169. Epub 2013 Dec 4. 26) Addition of taxane to induction therapy in head and neck malignancies: a systematic review and meta-analysis of randomized controlled trials. Perl G1, Ben-Aharon I, Popovtzer A, Stemmer SM, Vidal L. Chemotherapy. 2013;59(6):435-40. doi: 10.1159/000360690. Epub 2014 Jul 23. 27) Radiation exposure and attributed cancer risk following lung transplantation. Rosengarten D, Raviv Y, Rusanov V, Moreh-Rahav O, Fruchter O, Allen AM, Kramer MR. Clin Transplant. 2014 Mar;28(3):324-9. doi: 10.1111/ctr.12315. Epub 2014 Feb 8. 28) Factors associated with influenza vaccination among adult cancer patients: a case-control study. Vinograd I, Baslo R, Eliakim-Raz N, Farbman L, Taha A, Sakhnini A, Lador A, Stemmer SM, Gafter-Gvili A, Fraser D, Leibovici L, Paul M. Clin Microbiol Infect. 2014 Sep;20(9):899-905.doi: 10.1111/1469-0691.12625. [Epub ahead of print]. INFECTIOUS DISEASES 7/70, IF 5.197

29) The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy. Scherz-Shouval R, Santagata S, Mendillo ML, Sholl LM, Ben-Aharon I, Beck AH, Dias-Santagata D, Koeva M, Stemmer SM, Whitesell L, Lindquist S. Cell. 2014 Jul 31;158(3):564-78. doi: 10.1016/j.cell.2014.05.045. GY 2/185, IF 33.11

30) Selecting first-line bevacizumab-containing therapy for advanced breast cancer: TURANDOT risk factor analyses. Brodowicz T, Lang I, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Petruzelka L, Eniu A, Anghel R, Koynov K, Vrbanec D, Pienkowski T, Melichar B, Spanik S, Ahlers S, Messinger D, Inbar MJ, Zielinski C. Br J Cancer. 2014 Sep 30. doi: 10.1038/bjc.2014.504. [Epub ahead of print]. ONCOLOGY 42/202, IF 4.817

31) Dose escalation to rash for erlotinib plus gemcitabine for metastatic pancreatic cancer: the phase II RACHEL study. Van Cutsem E, Li CP, Nowara E, Aprile G, Moore M, Federowicz I, Van Laethem JL, Hsu C, Tham CK, Stemmer SM, Lipp R, Zeaiter A, Fittipaldo A, Csutor Z, Klughammer B, Meng X, Ciuleanu T. Br J Cancer. 2014 Sep 23. doi: 10.1038/bjc.2014.494. [Epub ahead of print]. ONCOLOGY 42/202, IF 4.817

32) Low molecular weight heparin (LMWH) for primary thrombo-prophylaxis in patients with solid malignancies - systematic review and meta-analysis. Ben-Aharon I, Stemmer SM, Leibovici L, Shpilberg O, Sulkes A, Gafter-Gvili AActa Oncol. 2014 Sep;53(9):1230-7. doi: 10.3109/0284186X.2014.934397. ONCOLOGY 63/202, IF 3.71

33) MicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells. Ninio-Many L, Grossman H,  Levi M,  Zilber S,  Tsarfaty I, Shomron N, Tuvar A, Chuderland D, Stemmer SM, Ben-Aharon I, Shalgi R Oncoscience 2014; 4:250-261. 34) Olaparib ,onotherapy in patients with advanced cancer and a germline BRCA1/2 mutation. Kaufman B, Shapira-Frommer R, Schmutzler RK, Audeh MW, Friedlander M, Balmaña J, Mitchell G, Fried G, Stemmer SM, Hubert A, Rosengarten O, Steiner M, Loman N, Bowen K, Fielding A, and Domchek SM. J Clin Oncol 2014; published Nov 3. (ONCOLOGY 5/202, IF 17.879) 35) Chemotherapy-induced vascular toxicity – Real-Time in vivo Imaging of Vessel Impairment. Bar-Joseph H, Stemmer SM, Tsarfaty I, Shalgi R, Ben- Aharon I. J Vis Exp 2014; in press. 36) Adjuvant docetaxel and cyclophosphamide (DC) with prophylactic granulocyte colony-stimulating factor (G-CSF) on days 8 &12 in breast cancer patients: a retrospective analysis. PLoS One. . Yerushalmi R, Goldvaser H, Sulkes A, Ben-Aharon I, Hendler D, Neiman V, Ciuraru NB, Bonilla L, Amit L, Zer A, Granot T, Rizel S and Stemmer SM. 2014 Oct 15;9(10):e107273. doi: 10.1371/journal.pone.0107273.

37) The association between infections and chemotherapy interruptions among cancer patients: Prospective cohort study. eCollection 2014. 8/55, IF 3.53Taha H, Vinograd I, Sakhnini A, Eliakim-Raz N, Farbman L, Baslo R, Stemmer SM, Gafter-Gvili A, Leibovici L, Paul M. Journal of Infection (2014)xx,1e7

38) MicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells. Ninio-Many, L., Grossman, H., Levi, M., Zilber, S., Tsarfaty, I., Shomron, N., Tovar A, Chuderland D, Stemmer SM, Ben-Aharon I, Shalgi, R. (2014). Oncoscience, 1(4), 250–261. 39) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal and appendiceal origin. Y. Berger, A.P. Zbar, A. Lebedyev, Y. Levi, A. Nevler, D. Aderka, T. Golan, O. Purim, B. Brenner, M. Natur, M. Gutman. Harefuah, 153:315-319. 40) Personalized prostate cancer screening among men with high risk genetic predisposition- study protocol for a prospective cohort study. D. Margel, O. Benjaminov, R. Ozalvo, L. Shavit Grievink, I. Kedar, R. Yerushalmi, I. Ben-Aharon, V. Neiman, O. Yossepowitch, D. Kedar, Z. Levy, M. Shohat, B. Brenner, J. Baniel, E. Rosenbaum. BMC Cancer, 14:528. 41) How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation? A. Vilkin, M. Halpern, S. Morgenstern, E. Brazovski, R. Gingold-Belfer, D. Boltin, O. Purim, Y. Kundel, S. Welinsky, B. Brenner, Y. Niv, Z. Levi. Human Pathology. 45:2029-36. 42) The 'real-life' impact of adding bevacizumab to first-line therapy in metastatic colorectal cancer patients: a large Israeli retrospective cohort study. A. Hammerman, S. Greenberg-Dotan, E. Battat, I. Feldhamer, H. Bitterman, B. Brenner. Acta Oncologica. 54:164-70. 43) Sphincter preservation in distal CT2N0 rectal cancer after preoperative chemoradiotherapy. N. Wasserberg, Y. Kundel, O. Purim, A. Keidar, H. Kashtan, E. Sadot, E. Fenig, B. Brenner. Radiat. Oncol. 9:233. 44) Expectations and Level of Satisfaction of Patients and their physicians: Concordance and discrepancies. Psychosomatics. G. Goldzweig, A. Abramovitch, B. Brenner, S. Perry, T. Peretz, L. Baider.

In Press.

45) Time of Conception and Birth-Relation of “Big Killers” Patients and Longevity. Stoupel E, Tamoshiunas A, Radishaukas R, Bernotiene G, Assali A, Vaknin H, Teplitzki I, Kornowski R, Abrambson E, Fenig E

Health 2014 6:3062-3066

46) Unilesional folliculotropic mycosis fungoides : a unique varian of cutaneous lymphoma. Amitay-Laish, Feinmesser M, Ben Amitai D, Fenig E, Sorin D, Hodak E. European Academy of Dermatology and Venereology. Doi 10.1111/jdv. 12851 47) Sphincter preservation in distal CT2N0 rectal cancer after preoperative chemoradiotherapy

Wasserberg N, Kundel Y, Purim O, Keidar A, Kashtan H, Sadot E, Fenig E, Brenner B. Radiat Oncol. 2014 Oct 22;9(1):233

48) Ismodegib as a Neoadjuvant Treatment to Mohs Surgery for Aggressive Basal Cell Carcinoma. Alcalay J, Tauber G, Fenig E and hodak E, J Drugs Dermatol. 2015;14 (2) 49) MRI to delineate the gross tumor volume of nasopharyngeal cancers: which sequences and planes should be used? Radiol Oncol. Popovtzer A, Ibrahim M, Tatro D, Feng FY, Ten Haken RK, Eisbruch A. 2014 Jul 10;48(3):323-30. doi:10.2478/raon-2014-0013. eCollection 2014 Sep. PubMed PMID: 25177248; PubMed Central PMCID: PMC4110090

50) Phase I trial of radiotherapy concurrent with twice-weekly gemcitabine for head and neck cancer: translation from preclinical investigations aiming to improve the therapeutic ratio. Popovtzer A, Normolle D, Worden FP, Prince ME, Chepeha DB, Wolf GT, Bradford CR, Lawrence TS, Eisbruch A. Transl Oncol. 2014 Aug;7(4):479-83. doi: 10.1016/j.tranon.2014.04.016. PubMed PMID: 25171890; PubMed Central PMCID: PMC4202797. 51) Elective neck dissection during salvage total laryngectomy - a beneficial prognostic effect in locally advanced recurrent tumours. Hilly O, Gil Z, Goldhaber D, Amit M, Biadsee A, Popovtzer A, Shvero J, Cohen J, Fliss D, Feinmesser R, achar G. Clin Otolaryngol. 2015 Feb;40(1):9-15. doi: 10.1111/coa.12309. PubMedPMID: 25145490. 52) How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation

Vilkin A1, Halpern M2, Morgenstern S3, Brazovski E4, Gingold-Belfer R1, Boltin D1, Purim O4, Kundel Y4, Welinsky S1, Brenner B5, Niv Y6, Levi Z7. Hum Pathol. 2014 Oct;45(10):2029-36