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Chapter 9 Survival Analysis and EM

Chapter 9 Survival Analysis and EM

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Chapter 9 Survival Analysis and EM !

Life-table estimates and KM estimates!

Log-rank test for equal hazards at ALL event times!

Crucial Implications!

Cox PH!

❖  Assume successive conditional independence, given the n_k values

Derivation of Partial Likelihood!

EM algorithm!

❖  Mu1 and sigma1 can be determined from raw data; So they are fixed in EM

❖  EM convergence can be slow

Self-consistency behind EM!

All are rank-based!