Fatty Acid Synthesis Occurs in the Cytosol
Citrate synthaseCitrate Lyase
Malate dehydrogenase
Malate EnzymePyruvate
carboxylase
Acetyl-CoA Carboxylase
Acetyl-CoA + HCO3- + ATP malonyl-CoA + ADP
Regulation of Acetyl-CoA Carboxylase (ACCase)
Animal Fatty Acid Synthase
Further Processing of Fatty acids: Desaturation and Elongation
Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine acyltransferase