Brooker

Chapter 11 Practice Problems What three components make up a nucleotide? Is DNA double stranded or single stranded? In DNA, name the purine and pyrimidine nitrogenous bases. Do purines bind with other purines, or do they bind pyrimidines? For the diagram below, label the following components of DNA:

Phosphodiester bond Hydrogen bond Pyrimidine Purine Deoxyribose 5’ ends 3’ ends

Are the two strands of DNA in a parallel or antiparallel orientation? What feature of the DNA molecule determines this orientation?

Brooker

What does Chargaff’s rule state? What are the four key features of DNA structure? What is the replication pattern (model) of DNA replication called? What are the primary steps and enzymes involved in DNA replication (that we discussed with the replication fork)? What are the leading and lagging strands in DNA replication? What orientation are these strands synthesized? What orientation are the parent strands for the leading and lagging strands in? What is the name of the newly synthesized DNA segments made on the lagging strand? What is/are the function(s) of DNA polymerase? Single-stranded binding protein? Helicase? DNA ligase? RNA primers? Topoisomerase? What is the name of the DNA clamp and what is its function? What is the location where replication begins called? What are telomeres? What enzyme maintains the length of telomeres? How does this enzyme maintain telomere length? DNA Replication Animation https://www.youtube.com/watch?v=gL3aigv7w4A