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Chapter 1
An Introduction to the
Human Body
Chapter 1: An Introduction to the Human
Body
Six levels of structural organization
1. Chemical level (atoms to molecules)
2. Cellular level (molecules are organized into cells)
3. Tissue level (groups of similar cells work together)
4. Organ level (two or more tissues become an organ)
5. System level (related organs with common functions)
6. Organismal level (all of the cells, tissues, and organ systems
become a human being)
The Six Levels of Structural Organization
Integumentary System
Skeletal System
Muscular System
Nervous System
Endocrine System
Cardiovascular System
Lymphatic System and Immunity
Respiratory System
Copyright 2010, John Wiley & Sons, Inc.
Digestive System
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Urinary System
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Reproductive Systems
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Basic Processes of Living Systems
Life differs from nonliving matter in these ways:
Metabolism - all of the chemical processes of life
Responsiveness - living systems detect and
respond to changes in their environments
Movement - cells, organs, and/or bodies move
Growth - cells, organs, and bodies all grow
Differentiation - the process of cellular specialization
Reproduction - both cells and organisms make copies of
themselves
Copyright 2010, John Wiley & Sons, Inc.
Homeostasis — A Fundamental Pattern
Found in All Living Systems
Homeostasis is the maintenance of relatively constant
conditions inside the body
First described by Claude Bernard in 1865, the term was coined
by Walter Cannon in the early 1900’s
Although conditions within the body are stable, this is a result of
many dynamic processes that constantly adjust internal activities
to match changing needs
Some examples of stable conditions are blood glucose, body
temperature, and blood pressure
Copyright 2010, John Wiley & Sons, Inc.
Homeostasis Interactions Animation
Communication, Regulation and
Homeostasis
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Copyright 2010, John Wiley & Sons, Inc.
Body Fluids - A Key Focus for Homeostasis
The volume and composition of the various fluids
within our bodies are carefully regulated
Our body fluids include:
Intracellular fluid - the fluid inside our cells
Extracellular fluid – all body fluids other than the ones inside our
cells. Can be subdivided according to location:
Interstitial fluid - the fluid between cells in tissues
Plasma - the fluid component of blood
Lymph - the fluid in our lymphatic vessels
Cerebrospinal Fluid (CSF) - the fluid within the CNS
Synovial fluid - the fluid within most joints
Copyright 2010, John Wiley & Sons, Inc.
Homeostasis - Restoring “Balance” to the Body
Feedback systems control our internal environment
Negative feedback systems act to stabilize the body in the face of
changing external and internal conditions. These systems cause
an opposite response to the initial change, and so are self-
limiting.
Positive feedback systems are important in specific situations,
when a very rapid or very strong effect is desired. Unlike negative
feedback, here the response is the same as that caused by the
initial change.
An outside event must break the positive feedback cycle.
Copyright 2010, John Wiley & Sons, Inc.
Negative Feedback Systems
Three essential components
receptor - detects changes in controlled conditions
control center - decides the type and amount of response
required
effector - reacts to signals from the control center and
produces the required response
The term “negative feedback” is used because the
response is opposite in direction to the original change
Copyright 2010, John Wiley & Sons, Inc.
Operation of a
Feedback System
Copyright 2010, John Wiley & Sons, Inc.
Negative Feedback – Temperature Interactions Animation
Negative Feedback Control of Temperature
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Copyright 2010, John Wiley & Sons, Inc.
Blood Pressure Regulation:
Homeostatic Regulation by Negative
Feedback Three essential components
baroreceptors - detect changes in blood pressure and
communicate with the brain
the brain - interprets information and sends signals to the heart
and blood vessels
heart and blood vessels - alter their activities based on signals
from the brain
Resulting in the blood pressure being restored to
normal
Copyright 2010, John Wiley & Sons, Inc.
Blood Pressure
Regulation
Copyright 2010, John Wiley & Sons, Inc.
Blood Pressure Regulation Interactions Animation
Negative Feedback Control of Blood
Pressure
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Copyright 2010, John Wiley & Sons, Inc.
Positive Feedback
A stimulus causes a response that reinforces the effect of
the stimulus
A positive feedback cycle must be stopped or limited by
some event or condition outside of the cycle
Copyright 2010, John Wiley & Sons, Inc.
Positive Feedback
Control of Labor
Copyright 2010, John Wiley & Sons, Inc.
Positive Feedback – Labor Interactions Animation
Positive Feedback Control of Labor
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Describing the Human Body
A set of standard terms is used to make descriptions of
the body more easily understood
Anatomical position - a reference position for the body
Body regions - a set of terms for body regions derived from Latin
and Greek are commonly used in Anatomy and Medicine
Directional terms - these terms describe locations (on or within
the body) relative to one another
Planes and sections - these terms help to describe internal
locations within the body or within an organ along defined cuts.
Body cavities - internal spaces within the body where many
organs are found, and where much of physiology happens
Copyright 2010, John Wiley & Sons, Inc.
Anatomical Position - The Standard Reference
Position for All of Anatomy
Copyright 2010, John Wiley & Sons, Inc.
Directional Terms
Copyright 2010, John Wiley & Sons, Inc.
Planes and Sections of the Body
A way to describe internal body locations
Sagittal plane
Midsagittal (or medial) plane
Parasagittal planes
Frontal (or coronal) plane
Transverse plane
A section is a view of the body cut along one of the
specific planes
Copyright 2010, John Wiley & Sons, Inc.
Planes and Sections of the Brain
The complexity of the brain shows the usefulness of planes and sections
Copyright 2010, John Wiley & Sons, Inc.
Body Cavities
Major internal body spaces
Cranial cavity
Vertebral cavity
Thoracic cavity
Abdominopelvic cavity
Abdominal cavity
Pelvic cavity
Copyright 2010, John Wiley & Sons, Inc.
Body Cavities
Copyright 2010, John Wiley & Sons, Inc.
Serous Membranes
Double-walled tissue membranes surround many
internal organs and line the body cavities in which
the organs are located.
Major examples include:
Pleura
Pericardium
Peritoneum
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Serous Membranes
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Serous Membranes
Copyright 2010, John Wiley & Sons, Inc.
Two Different Systems Exist for Describing
Locations within the Abdominopelvic Cavity