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Chapter 05 *Lecture Outline Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. *See separate Image PowerPoint slides for all figures and tables pre-inserted into PowerPoint without notes. PowerPoints prepared by Melanie Waite-Altringer Biology Faculty Member of Anoka-Ramsey Community College

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Page 1: Chapter 05 *Lecture Outline Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. *See separate Image PowerPoint

Chapter 05*Lecture Outline

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

*See separate Image PowerPoint slides for all figures and tables pre-inserted into

PowerPoint without notes.

PowerPoints prepared by Melanie Waite-AltringerBiology Faculty Member of

Anoka-Ramsey Community College

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Chapter 5

Tissues

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3

Introduction: A. Cells are arranged in tissues that

provide specific functions for the body.

B. Cells of different tissues are structured differently, which leads to their differences in function.

C. The tissues of the human body include four major types: epithelial, connective, muscle, and nervous.

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Epithelial Tissues:A. General Characteristics

1. Epithelial tissue is widespread throughout the body, covers

organs, and lines body surfaces.2. Epithelial tissues are anchored to a

basement membrane, are made up of tightly packed cells containing

little intercellular material, generally lack blood vessels, and are replaced frequently.

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3. Epithelial tissues function in protection, secretion, absorption, excretion, and sensory reception.

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B. Simple Squamous Epithelium1. Simple squamous epithelium is

made up of a single layer of thin, flattened cells.

2. Because it is suited for diffusion, it functions in the exchange of gases

in the lungs and lines blood and lymph vessels as well as body cavities.

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Fig05.01

(b)(a)

(d)(c)

Free surfaceof tissue

Simplesquamousepithelium

Basementmembrane

Nucleus

Free surfaceof simplesquamousepithelium

Nucleus

Connectivetissue

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©The McGraw-Hill Companies, Inc./Al Telser, photographer

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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C. Simple Cuboidal Epithelium

1. Simple cuboidal epithelium consists of a single

layer of cube-shaped cells with centrally located nuclei.

2. It functions in secretion and absorption in the

kidneys, and in secretion in glands.

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Fig05.02

Nucleus

Basement membrane

Free surface of tissue

Simplecuboidalepithelium

Connectivetissue

Lumen

(a) (b)©The McGraw-Hill Companies, Inc./Al Telser, photographer

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D. Simple Columnar Epithelium1. Simple columnar epithelium is

made up of a row of elongated cells

whose nuclei are all located near the basement membrane. It may be ciliated.

2. It lines the uterus, stomach, and intestines where it protects underlying

tissues, secretes digestive fluids, and absorbs nutrients.

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3. In the intestine, these cells possess microvilli that increase the

surface area available for absorption.4. Mucus-secreting goblet cells

can be found among columnar cells.

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Nucleus

Basementmembrane

Microvilli(free surfaceof tissue)

Connectivetissue

Mucus

Cytoplasm

Goblet cell

(a) (b)©The McGraw-Hill Companies, Inc./Al Telser, photographer

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E. Pseudostratified Columnar Epithelium

1. These cells appear layered due to the varying positions of their nuclei within the row of cells, but are not truly layered.

2. Cilia may be present, along with mucus-secreting goblet cells, that line and sweep debris from respiratory tubes.

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Fig05.04

(a) (b)

Cilia(free surfaceof tissue)

Goblet cell

Basement membrane

Nucleus

Connective tissue

Cytoplasm

©The McGraw-Hill Companies, Inc./Dennis Strete, photographer

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F. Stratified Squamous Epithelium

1. This type of tissue is made up of layers of flattened cells that

are designed to protect underlying layers.

2. It makes up the outer layer of skin, and lines the mouth, throat, vagina, and anal canal.

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3. In the skin, outer layers of cells undergo keratinization; however, this process does not occur where tissues remain moist in the throat, vagina, or anal canal.

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Fig05.05

Basement membrane

Layer ofdividingcells

Connectivetissue

Free surfaceof tissue

Squamouscells

(b)(a)©The McGraw-Hill Companies, Inc./Al Telser, photographer

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G. Stratified Cuboidal Epithelium1. This tissue consists of two to

three layers of cuboidal cells lining a lumen of the mammary glands, sweat glands, salivary glands, and pancreas.

2. Several layers of cells provide greater protection than one single layer.

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Fig05.06

Free surface of tissue

Lumen

Basement membrane

Connective tissue

Nucleus

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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Stratifiedcuboidalepithelium

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H. Stratified Columnar Epithelium

1. This tissue consists of several layers of cells and is found in the ductus deferens, part of the male urethra,

and parts of the pharynx.

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(b)(a)

Lumen

Stratified columnar epithelium

Connectivetissue

Basement membrane

Free surface of tissue

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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I. Transitional Epithelium1. Transitional epithelium is

designed to distend and return to its normal size, as it does in the lining of the urinary bladder.

2. This design provides distensibility and keeps urine from diffusing back into the internal cavity.

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Fig05.08

©Ed Reschke

©Ed Reschke

Stretched transitional epithelium

Basement membrane

Underlying connective tissue

Basement membrane

Underlying connective tissue

Unstretched transitional epithelium

(b)(a)

(d)(c)

Free surface of tissue

Free surface of tissue

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J. Glandular Epithelium1. This tissue is made up of cells

designed to produce and secrete substances into ducts or into body fluids.

2. Glands that secrete products into ducts are exocrine; those that secrete into body fluids and blood are called endocrine.

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3. Glands are classified by the ways the glands secrete their products.

a. Merocrine glands release fluid products by exocytosis (pancreas) and are grouped

as serous which produce a watery fluid or

mucus which produce a thicker, protective substance.

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b. Apocrine glands lose portions of their cell bodies during secretion (mammary glands).

c. Holocrine glands release entire cells (sebaceous glands).

CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display.Fig05.09

(a) Merocrine gland (b) Apocrine gland (c) Holocrine gland

Secretion

Pinched-off portion of cell (secretion)Intact

cell

Disintegrating cell and its contents (secretion)

Cell dividing

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Connective Tissues:A. General Characteristics

1. Connective tissues bind, support, protect, serve as frameworks,

fill spaces, store fat, produce blood cells, protect against infection, and repair tissue damage.

2. Unlike epithelial tissues, connective tissues have an abundance of extracellular matrix, or

intercellular material, throughout, and have good blood supplies (except cartilage).

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3. Major Cell Types

a. The fibroblast is the most common cell type, and is a

fixed, star-shaped cell that secretes fibers and is large in size.

b. Wandering macrophages function as scavenger cells and defend against infection.

c. Mast cells are large and are located near blood vessels

where they release heparin (anticoagulant) and

histamine (promotes inflammation).

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Fig05.10

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Macrophage

Fig05.11

Cell being engulfed

©Manfred Kage/Peter Arnold/Photolibrary

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Fig05.12

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4. Connective Tissue Fibers a. Strong collagenous fibers

(white fibers), made of the protein collagen, add strength for holding body parts together.

b. Elastic fibers (yellow fibers), made of the protein elastin, are stretchy and add flexibility to certain types of connective tissues.

c. Reticular fibers are thin collagenous fibers that form supportive networks in a variety of tissues.

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B. Categories of Connective Tissue1. Loose connective Tissue includes

areolar, adipose and reticular connective tissues.

a. Areolar Tissue forms delicate, thin membranes throughout

the body that bind body parts together such as skin and underlying organs.

i. The majority of the cells are fibroblasts that are separated by a gel-like ground substance that contains collagenous and elastic fibers.

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Fig05.13

Elastic fiber

(a) (b)

Collagenous fiber

Fibroblast

Ground substance

©The McGraw-Hill Companies, Inc./Dennis Strete, photographer

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b. Adipose Tissue is loose connective tissue

designed to store fat.i. It is found beneath the

skin, around joints, padding the kidneys and other internal

organs, and in certain abdominal

membranes.

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Fig05.14

(a) (b)

Fat droplet

Nucleus

Cell membrane

y.

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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c. Reticular connective tissue is composed of thin, collagenous fibers in a 3-D network.

i. It helps to provide framework of certain internal organs (liver and spleen).

35

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2. Dense Connective Tissue

a. This tissue consists of densely packed collagenous fibers and is very strong but lacks a good

blood supply.b. It is found as part of

tendons and ligaments.

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Fig05.15

Fibroblasts

Collagenous fibers

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3. Cartilage

a. Cartilage is a rigid connective tissue that provides a supportive framework for

various structures. It lacks a vascular system and so

heals slowly.b. Cartilage cells

(chondrocytes) lie within lacunae in the gel-

like fluid matrix.

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c. Cartilaginous structures are enclosed within a connective tissue called the perichondrium.

d. The most common, hyaline cartilage, is white with abundant fine collagen fibers,

is found at the ends of bones, and supports respiratory

passages.

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e. Elastic cartilage, with elastic fibers, provides a framework for the external ears and parts

of the larynx.f. Fibrocartilage, with

many collagenous fibers, is a tough tissue that provides a shock-

absorbing function in intervertebral discs and

in the knees and pelvic girdle.

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Fig05.16

Chondrocyte

Nucleus

Extracellular matrix

(a) (b)

Lacuna

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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Fig05.17

Chondrocyte

Elastic fibers

Nucleus

Extracellular matrix

(a) (b)

Lacuna

©The McGraw-Hill Companies, Inc./Al Telser, photographer

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Fig05.18

Chondrocyte

Nucleus

Collagenous fiber

Extracellular matrix

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4. Bone

a. Bone is the most rigid connective

tissue, with deposits of mineral salts and collagen within the matrix.

b. Bone internally supports the body, protects, forms muscle attachments and is the site for

blood cell formation.

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c. Bone cells, called osteocytes, lie within lacunae and are arranged in concentric circles

(osteons) around osteonic canals interconnected

by canaliculi.d. Bone has a good blood

supply, enabling rapid recovery after an injury.

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Fig05.19

Canaliculi

Lacuna

Central canal

Lamella

Osteon

©The McGraw-Hill Companies, Inc./Dennis Strete, photographer

(c)©Prof. P. Motta/Univ."La Sapienza"/Photo Researchers

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(a) (b)

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5. Blood a. Blood is composed of

cells (red and white) suspended in a liquid matrix called plasma.

b. It functions to transport substances

throughout the body.

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Fig05.20

Red blood cells

Plasma(extracellularmatrix of blood)

Platelets

White blood cell

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Types of Membranes:A. Epithelial membranes are thin,

sheetlike structures composed of epithelium and connective tissues, covering body surfaces and lining body cavities.

B. The four main types are: serous, mucous, cutaneous, and synovial.

49

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Muscle Tissues:A. General Characteristics 1. Muscle cells, or fibers, can contract

and consist of three major types: skeletal, smooth and cardiac.

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B. Skeletal Muscle Tissue

1. Skeletal muscle is attached to bone and can be controlled by conscious effort (voluntary).

2. The cells (muscle fibers) are long and

cylindrical, striated, have many nuclei and contract

from nervous impulse.

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Fig05.21

Striations

Portion of amuscle fiber

Nuclei

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C. Smooth Muscle Tissue1. Smooth muscle tissue lacks

striations, is uninucleate, and consists of spindle-shaped cells.

2. This involuntary muscle is found in the walls

of internal organs, and in the digestive tract, blood vessels, and

urinary bladder.

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Fig05.22

Nucleus

Cytoplasm

(a) (b)©The McGraw-Hill Companies, Inc./Dennis Strete, photographer

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D. Cardiac Muscle Tissue

1. Cardiac muscle tissue is found only in the heart and consists of branching fibers that are connected

to each other with intercalated discs.

2. This involuntary muscle has a single nucleus in each cell but appears striated.

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Fig05.23

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Intercalated disc

Nucleus

Striations

(a) (b)©The McGraw-Hill Companies, Inc./Al Telser, photographer

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Nervous Tissues: A. Nervous tissues are found in the

brain, spinal cord, and nerves.

B. Neurons, or nerve cells, conduct nervous impulses while

helper cells, or neuroglia, support and nourish the neurons.

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Fig05.24

Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

(a) (b)

Nucleus

Cell membrane

Cytoplasm

Cellular process

Nuclei of neuroglia

©Royalty-Free/Corbis