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    36.2 Human Development

    Before Birth

    Bio 30 NWRC

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    Fertilization ( find another video)

    Ovulation

    Fertilization

    (occurs in the oviduct)

    Implantation in theuterus

    http://uk.youtube.com/watch?v=2eelyg_k5iwhttp://uk.youtube.com/watch?v=2eelyg_k5iw
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    Fertilization

    Only 1 sperm fertilizes

    the egg but 100s are

    needed to bombard and

    break down the eggs

    plasma membraneonce the eggs

    membrane is weakened

    and a sperm penetrates it

    the egg forms a barrierwhich does not allow any

    other sperm to enter.

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    Early Development

    Morula

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    From One Cell to Blastula to

    Blastocyst

    http://uk.youtube.com/watch?v=UgT5rUQ9EmQ&NR=1http://uk.youtube.com/watch?v=UgT5rUQ9EmQ&NR=1
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    ExtraEmbryonic Membranes

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    ExtraEmbryonic MembranesAmnion:A thin, tough,

    membranous sac that enclosesthe embryo. It is filled with a fluidin which the embryo issuspended.

    Chlorion:The outer membrane

    enclosing the embryo in reptiles,birds, and mammals. In placentalmammals it contributes to thedevelopment of the placenta.Yolk Sac: Functions as the

    circulatory system of the humanembryo before internalcirculation begins.

    Allantois:It is important in theformation of the umbilical cord

    and placenta in mammals.

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    The PlacentaThe placenta is partially

    of fetal origin and partly

    of maternal origin The

    fetal portion is composed

    of highly specialized cells

    from the outermost

    embryonic membrane,which form projections

    that contain the fetal

    blood vessels. These

    projections are called

    chorionic villi. Thematernal portion is

    formed by a modification

    of the lining of the uterus,

    and the fetal villi grow

    into the uterine lining

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    The umbilical cord inserts into the fetal surface.

    Note the vessels radiating out from the cord over

    the fetal surface in this normal term placenta.

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    The Placenta

    Basically, the

    placenta is made up

    of a combination of

    cells from the motherand the growing baby

    The mother and the

    fetus both have their

    own circulatorysystems

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    3 Trimesters of Development

    FIRST TRIMESTER

    At the end of 8 weeks

    the embryo is called a

    fetus. All the organsystems have begun

    to form by the end of

    the 1st trimester the

    fetus can move andhas fingerprints.

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    This little boy is at 9 weeks gestational age of

    embryonic life. Note the thin amnionic cavity

    surrounding the embryo.

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    First Trimester

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    3 Trimesters of Development

    Second TRIMESTER

    The fetus has now

    developed all its

    organs and systemsand will now focus on

    growing in size and

    weight.

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    3 Trimesters of Development

    Third TRIMESTER

    During the third

    trimester, the fetus

    continues to grow insize and weight. The

    lungs are still

    maturing and the

    fetus begins toposition itself head-

    down.

    Link to website: The

    Visible Embryo

    http://www.visembryo.com/baby/index.htmlhttp://www.visembryo.com/baby/index.htmlhttp://www.visembryo.com/baby/index.htmlhttp://www.visembryo.com/baby/index.html
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    Diagnosis in the Fetus

    Ultrasound A sonogramprovides images of theinfant in the womb. Itcan be used to

    Judge gestation

    Measure fetal growth

    Evaluate abnormalities

    Reveal the sex of fetus

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    Diagnosis in the Fetus

    Amniocentesis: Asample of amniotic fluidcan be withdrawn andanalyzed (fluid contains

    fetal cells). It is usefulfor

    Diagnosing sex linkeddisorders

    Chromosomal defects

    Sex can also bedetermined

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    Diagnosis in the Fetus

    Chorionic VillusSampling (CVS)

    Tissue is taken frommembrane surrounding

    the fetus. Can test for: (1) Chromosomal

    abnormalities.

    (2) Some inheriteddisorders. Dominant,Recessive and X-linkedpatterns of inheritance.

    End of 35-2

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    Assessment

    1. The zygote divides

    by mitosis and

    becomes a morula

    (solid ball of cells)The morula hollows

    out and becomes a

    blastocyst.

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    Assessment

    2. The barrier

    surrounding the egg

    could not be

    penetrated andfertilization would not

    occur

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    Assessment

    3. refer to notes-

    there is too much

    information to

    summarize on a slide.

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    Assessment

    4. During pregnancyprogesterone andestrogen levelsremain highpreventing anothermenstrual period.During a menstrualperiod levels of

    progesterone andestrogen drop nearthe end of the cycle.