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Center for the ironmental Implications of Nanotecholo Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science Foundation Directorate for Biological Sciences Directorate for Education and Human Resources Directorate for Engineering Directorate for Geosciences Directorate for Mathematical & Physical Sciences Directorate for Social, Behavioral & Economic Sciences Alan J. Tessier, Lead Program Officer BIO/Division of Environmental Biology Environmental Protection Agency Nora Savage, Lead Program Officer EPA/Office of Research & Development National Center for Environmental Research

Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

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Page 1: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Center for the Environmental Implications of Nanotechology

Program Solicitation NSF 07-590

Preliminary Proposal Due:December 10, 2007

National Science FoundationDirectorate for Biological SciencesDirectorate for Education and Human ResourcesDirectorate for EngineeringDirectorate for GeosciencesDirectorate for Mathematical & Physical SciencesDirectorate for Social, Behavioral & Economic Sciences

Alan J. Tessier, Lead Program Officer BIO/Division of Environmental Biology

Environmental Protection Agency

Nora Savage, Lead Program Officer EPA/Office of Research & Development National Center for Environmental Research

Page 2: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Center for the Environmental Implications of Nanotechology

Preliminary Proposal Due: December 10, 200715 page project description

Anticipated Funding Amount: $5 M/year for 5 years ($4M/yr NSF, $1M/yr EPA)Possibility of one 5-year renewal

No cost share required

Full proposal deadline: March 17, 2008 (invitation only)

Page 3: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

CEIN Goals and Structure:

“A National Center that will conduct fundamental research and education on the short- and long-term impact of nanotechnology on the environment and livingsystems at all scales.”

“A multidisciplinary research approach involving the biological, chemical, physical,computational, mathematical, social and behavioral sciences will be needed to understand the fundamental processes and related risks associated with the interaction of naturally derived and engineered nanomaterials in the environmentand living systems.”

“The CEIN will address the implications of nanotechnology on environmental healthand safety through fundamental research on the interactions of nanomaterials withthe living world at all scales.”

Page 4: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

CEIN Research and Education Focus:

1. Understanding the bioaccumulation of nanomaterials and their effects on living systems including their routes of environmental exposure, deposition, transformation, bio-persistence, clearance, and translocation, as well as mechanisms for their adsorption, distribution, metabolism, and excretion by organisms.

2. Understand the interactions of nanomaterials with cellular constitutents, metabolic networks and living tissues including interactions at the molecular, cellular, organ, and systemic levels,and effects on organisms ontogeny and multi-generational life histories.

3. Determining the biological impacts of nanomaterials dispersed in the environment includingthe ecological and evolutionary effects of nanomaterials on aquatic and terrestrial ecosystemssuch as: species interactions, factors that contribute to bioaccumulation and biomagnificationof nanomaterials in food webs, distribution of nanomaterials and their byproducts within ecosystems, biotic processes that influence the persistence and chemical transformations ofnanomaterials in the environment, and the mode and duration of effects on ecosystems.

Page 5: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Transforming Nanotechnology into a Tool to Solve Real-World Problems

CBEN’s mission is to discover and develop nanomaterials that enable new medical and environmental technologies.

The mission is accomplished by the following:

• Fundamental examination of the ‘wet/dry’ interface between nanomaterials, complex aqueous systems, and ultimately our environment (Theme 1).

•Engineering research that focuses on multifunctional nanoparticles that solve problems in environmental and biological engineering (Themes 2, 3).

•Educational programs that develop teachers, students, and citizens who are well informed and enthusiastic about nanotechnology.

•Innovative knowledge transfer that recognize the importance of communicating nanotechnology research to the media, policymakers, and the general public.

Center for Biological and Environmental NanotechnologyRice University

Page 6: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Center for Biological and Environmental NanotechnologyRice University

Theme 1: Nanoscience at the Wet/Dry Interface• Nanomanufacturing: Materials Design and Production• Forming, Characterizing and Optimizing Bionanoconjugates• Developing SWNTs as Biological Materials

Theme 2: Nanoparticles that Detect and Treat Disease• Immunotargeted NIR Contrast Agents for Cancer Imaging• Functional Imaging of Gene Expression• NIR-absorbing Particles for Cancer Therapy• Protease-activated Imaging Agents for Therapeutics• Engineering Self-Organized Nano-Biomechanical Resonators• Nanoparticle-cell: Structure-function Relationships for Cytotoxicity

Theme 3: Effective, High-Performance Water Purification Systems • Arsenic Removal using Nanoscale Magnetite• Metal Nanocatalysts for Reducing Organics in Water• Disinfection and Biofouling Control• The Environmental Chemistry of Nanoscale Carbons• Fate and Transport of Engineered Nanoparticles• Environmental Toxicology, Biological Interactions and Bioavailability of Fullerenes

Health, Environmental, and other Societal Impacts • Assessing Public Trust and Perceptions of Risk• The Ethics and Politics of Nanotechnology

Research Activities listed on website

Page 7: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Nano/Bio Interface CenterThe University of Pennsylvania

Biomolecular Optoelectronic Function Molecular Motions

Single Molecular Probes Ethics of Nanotechnology

 

Research Areas listed on website

Page 8: Center for the Environmental Implications of Nanotechology Program Solicitation NSF 07-590 Preliminary Proposal Due: December 10, 2007 National Science

Meeting Objectives:

• Develop a preliminary OU vision and research foci

• Identify currently available resources at OU and in Oklahoma- faculty and staff- equipment and facilities- governmental and industrial partners

• Identify resources necessary to obtain in order to be competitive

• Organize a working committee - identify potential members not present

• List potential candidates for PI / Center Director