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CENTER FOR SMELL AND TASTE News and Announcements University of Florida Director’s Musings Page 1 Featured Member Page 2 This Month’s Chemical Senses Seminar Page 3 UFCST Fall 2014 Seminar Schedule Page 4 NIH Announcements Page 5 Upcoming Chemical Senses Meetings Page 6 In This Issue Musings from the Director….. Last month was an especially busy one for our chemical senses community, with five closely‐spaced seminars of interest. This month we return to our normal monthly schedule with a talk by Dr. Elissa Hallem (see item 3). Dr. Hallem has been involved in chemical senses research since her days as a graduate student studying olfaction with Dr. John Carlson at Yale, and was the recent recipient of a MacArthur ‘Genius’ Award, so we’re really looking forward to her visit. Speaking of insect olfaction, we are very fortunate to have a large branch of the US Department of Agriculture/Agricultural Research Service located on the UF campus. Twelve of their scientists actively study the chemical senses of vector and pest insects and are members of the Center. To help showcase this important scientific connection, we present one of their scientists, Dr. Al Handler, as this month’s featured member (see item 2). Finally, just a reminder to begin planning to attend and participate in the annual chemical senses (AChemS) meeting, which is being held next April in Ft. Meyers, FL (see item 6). I mention it now since the abstract deadline for this meeting falls immediately after the Holidays and always seems to catch one by surprise so it’s good to plan well in advance. November 1, 2014 Issue No: 2014‐07 Page1

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CENTER FOR SMELL AND TASTE News and Announcements

University of Florida

Director’sMusingsPage1FeaturedMemberPage2ThisMonth’sChemicalSensesSeminarPage3UFCSTFall2014SeminarSchedule

Page4 NIHAnnouncements Page5

UpcomingChemicalSensesMeetings Page6

InThisIssue

Musings from the Director…..

Lastmonthwasanespeciallybusyoneforourchemicalsensescommunity,withfiveclosely‐spacedseminarsofinterest.ThismonthwereturntoournormalmonthlyschedulewithatalkbyDr.ElissaHallem(seeitem3).Dr.HallemhasbeeninvolvedinchemicalsensesresearchsinceherdaysasagraduatestudentstudyingolfactionwithDr.JohnCarlsonatYale,andwastherecentrecipientofaMacArthur‘Genius’Award,sowe’rereallylookingforwardtohervisit.

Speakingofinsectolfaction,weareveryfortunatetohavealargebranchoftheUSDepartmentofAgriculture/AgriculturalResearchServicelocatedontheUFcampus.TwelveoftheirscientistsactivelystudythechemicalsensesofvectorandpestinsectsandaremembersoftheCenter.Tohelpshowcasethisimportantscientificconnection,wepresentoneoftheirscientists,Dr.AlHandler,asthismonth’sfeaturedmember(seeitem2).

Finally,justaremindertobeginplanningtoattendandparticipatein

theannualchemicalsenses(AChemS)meeting,whichisbeingheldnextAprilinFt.Meyers,FL(seeitem6).ImentionitnowsincetheabstractdeadlineforthismeetingfallsimmediatelyaftertheHolidaysandalwaysseemstocatchonebysurprisesoit’sgoodtoplanwellinadvance.

November1,2014IssueNo:2014‐07Page1

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Contact:

[email protected]

Featured Member

Dr. Alfred Handler ResearchGeneticist

InsectBehaviorandBio‐controlResearchUnitCenterforMedical,Agricultural,andVeterinaryEntomology

AgriculturalResearchServiceUSDepartmentofAgriculture

Gainesville,FL

Thismonthwe'repleasedtofeatureoneofourchemicalsensescolleaguesfromtheUSDA/ARSfacilityhereinGainesville.Dr.HandlerisaResearchGeneticistwhohasmadenumerousfundamentalcontributionstounderstandingandmanipulatingthegenesoftephritidfruitflies,agroupofinvasivepestsofgreatagriculturalimportancebothintermscroplossandtheestablishmentoftradebarriers.

AfterstudiesindicatedthatthePelementtransformationvectorwasnon‐functionalbeyonddrosophilidspecies,heutilizedthepiggyBactransposontotransformseveraltephritidpestspeciesincludingthecaribfly(Anastrephasuspensa),medfly(Ceratitiscapitata)andorientalfruitfly(Bactroceradorsalis).Hehassincetestednewconditionalautocidaltechniquesthatpromisetoreplacetheirradiationofmales,ameansofinducingsterilitythatcanseriouslydegradethesexualperformanceofinsectsdestinedforSITmass‐releases.Morerecently,Dr.Handlerhasturnedhisattentiontoeliminatingthepossibilityofinadvertenthorizontaltransferofexoticgenesintonon‐targetpopulationsandspecies.Thisenvironmentalriskhasbeenaprincipalobstacletothemorewidespreaduseofgeneticallymodifiedinsectsinbiologically‐basedcontrolprogramsanditsremovalcouldcontributetoagenetic‐transformationrenaissanceinthefieldofentomology.Heandcolleagueshavebeenawardedapatentforthissystemofvectorimmobilizationthatcanbeimplementedwithanovelmethodoftargetingtransgenesintopre‐evaluatedgenomicinsertionsites(“Systemsforgenetargetingandproducingstablegenomictransgeneinsertions”).Dr.HandlerisalsotheconsortiumleaderfortheMedflyWholeGenomeSequencingProjectwhosefirstmanualannotationshavebeenjustcompleted,whichincludesbindingproteinsand/orreceptorsforodorant,gustatoryandionotrophicmolecules.

WearemostpleasedtohaveDr.HandlerandalltheUSDAscientistsasmembersofouractiveandgrowingchemicalsensesresearchcommunity.

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ThisMonth’sChemicalSenses’Seminartomorrow!Wednesday,November5,2014

‘Odor‐drivenhostseekinginskin‐penetratingparasiticnematodes’

Dr.ElissaHallem,PhD

AssistantProfessor,DepartmentofMicrobiologyImmunologyandMolecularGeneticsUniversityofCalifornia,LosAngelesLosAngeles,CAWednesday,November5,201412Noon,DeWeeseAuditoriumRm.LG‐101A,McKnightBrainInstitute,UniversityofFlorida

Skin‐penetratingparasiticnematodesinfectapproximatelyonebillionpeopleworldwideandareresponsibleforsomeofthemostcommonneglectedtropicaldiseases.Theinfectivelarvaesearchforhostsusingsensorycues,yettheirhost‐seekingbehaviorispoorlyunderstood.Dr.Hallemisconductinganin‐depthanalysisofhostseekingintheskin‐penetratinghumanthreadwormStrongyloidesstercoralis,andcomparingitsbehaviortothatofotherparasiticnematodes.Itdisplaysrobustattractiontoadiversearrayofhumanskinandsweatodorants,manyofwhichinterestinglyalsoattractmosquitoes.Dr.Hallemalsoinvestigatestheneuralbasisofhost‐seekingbehaviorforinsightintohowsensoryneuralcircuitsdifferinfree‐livingvs.parasiticspeciesofnematodestoenablethedevelopmentofnewstrategiesforcombatingharmfulnematodeinfections.

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UFCST’s

ChemicalSensesFallSeminarSeries

Incaseyouhaven’talreadydoneso,besuretosavethedatesfortheremainderofourFallseminarseries.AllseminarsareheldatNoonintheDeweeseAuditoriumintheMcKnightBrainInstitute,1149NewellDr.Don’tforget,theseminarsarefollowedimmediatelybyameet‐the‐speakerluncheonforgraduatestudentsandpostdocswhosignupinadvance([email protected]).

***************Wednesday,December3rd–Dr.JayGottfreid(AssociateProfessorofNeurology,NorthwesternUniversity)

Dr.Gottfreidisanemergingleaderinclinicalaspectsofolfactionwhouseshigh‐resolutionfunctionalmagneticimagingcomputationaltechniquesandpsychophysiologicalparadigmstobetterunderstandtheprofoundimpairmentinthesenseofsmellassociatedwithAlzheimer’sdisease.

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LUNCHWITHTHE

SPEAKERSIMMEDIATELYFOLLOWSTHESEMINAR

Facultyareremindedtoencouragetheirpostdocsandgradstudents(sorry,nofaculty)totakeadvantageoftheopportunitytomeetwitheachofourspeakersimmediatelyfollowingtheirseminar.

TheseluncheonsareprovidedatnochargeandareheldjustupstairsfromtheseminarroomintheMBIconferenceroom,RmL5‐101B.Taketheelevatortothe5thfloorandturnrightimmediatelyonexitingtheelevator.

Ifyouhaveastudentorpostdocwhowouldliketotakeadvantageofthisopportunity,pleasehavethemcontactCheriBrown([email protected])toreserveaspotsinceseatingislimited.

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NIH Announcements

NIDCDSmallGrantProgram(R03)(PAR‐13‐057)NationalInstituteonDeafnessandOtherCommunicationDisordersApplicationReceipt/SubmissionDate(s):February26,2013;June26,2013;October18,2013;February26,2014;June262014;October28,2014;February26,2015;June26,2015;October28,2015

NIDCDClinicalResearchCenterGrant(P50)(PAR‐13‐062)NationalInstituteonDeafnessandOtherCommunicationDisordersApplicationReceipt/SubmissionDate(s):February,22,2013;May30,2013;October1,2013;January30,2014;June2,2014;October1,2014;February2,2015;June6,2015;October,1,2015

NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01) (PAR-14-009) National Institute on Deafness and Other Communication Disorders Application Receipt/Submission Date(s): June 23, 2014, February 23, 2015, October 23, 2015, June 23, 2016, February 23, 2017

Notice of Participation of NIDCD in RFA-NS-13-013 Collaborative Research on Chronic Traumatic Encephalopathy and Delayed Effects of Traumatic Brain Injury: Neuropathology and Neuroimaging Correlation (U01) (NOT‐DC‐13‐004)National Institute on Deafness and Other Communication Disorders

Notice of Participation of NIDCD in RFA-NS-13-014 Pilot Projects on Sports-Related Brain and Spinal Cord Injury Research (R21) (NOT‐DC‐13‐005)National Institute on Deafness and Other Communication Disorders

Notice of Participation of NIDCD in RFA-NS-13-015 Pilot Projects on Sports-Related Brain and Spinal Cord Injury Research (R03) (NOT‐DC‐13‐006)National Institute on Deafness and Other Communication Disorders

NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01) (PAR-14-009) National Institute on Deafness and Other Communication Disorders Application Receipt/Submission Date(s): June 23, 2014, February 23, 2015, October 23, 2015, June 23, 2016, February 23, 2017

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~~~~~~~~~~~~~~~~

UFCST Travel graduate students and

postdocs ~~~~~~~~~~~~~~~~

TheCenterprovidestravelawards

forgraduatestudentsandpostdocsattheUniversityof

Floridaonanongoingbasis.Weencourageapplicationsfrom

youngscientistswhosemainareaofinterestisnotthechemicalsenses,butwhowouldbenefitfromexposuretothefield.WewillalsoconsiderrequestsfromgraduatestudentsandpostdocsactivelyworkinginthechemicalsensestoattendtheAChemS

annualmeetingorotherscientificmeetingsofrelevancetochemicalsensesresearch.Pleasesubmit

requestsforsupportintheformofalettertotheCenterofficeat

ufcst@ufl.eduatleastonemonthbeforethestartofthemeeting.Pleaseincludeintherequestthe

estimatedcostoftravel,registration,andhousingwhileatthemeeting,andwhetherornotyouintendtomakeascientificpresentation.Graduatestudentsshouldsubmitlettersthatarecountersignedorotherwisesupportedbytheirmentor.UFCSTTravelAwardswillbegovernedbytheUniversityofFloridatravelguidelines.

Upcoming Chemical Senses Meetings

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November20‐21,2014SmellandTaste06Dresden,Germanyhttp://goo.glHbrJcUNovember21‐23,2014ClinicalCHEMOSENSATION2014Dresden,Germanyhttp://goo.gl/5STBhSDecember8‐9,2014DigitalOlfactionSociety2014TokyoInstituteofTechnologyJapanwww.olfaction‐site.comApril22‐25,2015AChemS37thAnnualMeetingHyattRegencyCoconutPointBonitaSprings,FLhttp://www.achems.org/i4a/pages/index.cfm?pageid=3962June5‐9,2016ISOT2016–17thInternationalSymposiumonOlfactionandTasteYokohama,Japanhttp://www.isot2016.com/