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Cellular Respiration Final

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8/3/2019 Cellular Respiration Final

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CellularRespiration

HarvestingChemicalEnergy

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• Organic compounds store energy in

their chemical bonds• Fats, carbs (CH2O), & proteins can all

be used as fuel .

 – Traditionally, cellular respiration is studiedusing glucose as the source.

• There are 2 energy-providing (catabolic)

pathways – Cellular Respiration

 – Fermentation (no oxygen is used)

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Cells Recycle ATP

(Breaking down food)

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Cellular Respiration

C6H12O6 + 6O2 6CO2 + 6H2O + Energy

Look familiar?

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Aerobic respiration

Step Where Action

Glycolysis Cytoplasm Glucose intopyruvate

Transitionreaction

Mitochondrialboundary

Pyruvate into AcetylCoA and CO2

Krebs cycle Mitochondrial

matrix

Acetyl CoA into

CO2 and electroncarriers 

ElectronTransport

Chain

Inner membrane ofmitochondria

Electrons passed toO2 to make H2O

and ATP

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Glycolysis

Splits a glucosemolecule into2 3-Carbonmolecules calledPYRUVATE.

products: ATP, NADH and pyruvate

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Preparation for the Krebs Cycle

The pyruvate loosesa carbon leaving the

2-carbon moleculeAcetyl CoA

CC

CO2

products: CO2, Acetyl CoA and NADH

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The Krebs Cycle

Products:

 CO2, ATP, NADH, FADH2

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Electron Transport

The mitochondria hastwo membranes: theouter and the inner,

which is convoluted.

H+ (protons)accumulatebetween these two

membranes.

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The matrix is a protein rich solution that contains the

enzymes that run electron transport.

ATP SYNTHASE = enzyme responsible for making ATP.

Mitochondria

outer membrane

inner membrane( ATP synthase)

matrix

H+

H+

H+

H+H+H+

H

+

H+NAD

H+

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• e-

are passed back and forth across themembrane.• Their energy is gradually decreased andused to actively transport H+ through themembrane.

• Oxygen is the final electron acceptor

•It joins with the H+ to produce H2O. 

If there is no oxygen, the electron chain cannot

continue. There is no way to release electrons.

electrons

Electron Transport Chain

Needs: O2  Products:  ATP & H2O 

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Products of the Electron Transport Chain

34 ATP

Water

+

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What is produced from one glucose molecule? 

Each NADH 3 ATP Each FADH2 2 ATP

Step Makes ATP created

Glycolysis 2 NADH 6

Transition reaction 2 NADH 6 

Krebs cycle 6 NADH

2 FADH2

18

Electron Transport Chain subtotal 34

ATP created directly

(2 during glycolysis and 2 in Krebs cycle)

4

TOTAL ATP CREATED 38

In the Electron Transport Chain…… 

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1. Glycolysis

Where:

Uses:

Produces: 

2. Transition reaction Where:

Uses:

Produces: 

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3. Krebs Cycle

Where:

Uses:

Produces: 

4. Electron Transport Chain Where:

Uses: 

Produces: 

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What happens when there is no oxygen

to accept the electrons?Only glycolysis is carried out.

In humans Lactic acid is produced. The cells

cannot tolerate much lactic acid.

Build up of lactic acidresults in “burning”

sensation

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Alcoholic Fermentation

•Some organisms carry out alcoholic fermentation. This

was discovered by Louis Pasteur in his study of wines.

•Yeasts break down the sugars in the juice to pyruvate

by glycolysis.•Then the pyruvate is dismantled to yield

CO2 and ETHANOL (booze).

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Some organisms do this

Others do this 

Alcohol fermentation

Lactic acid fermentation

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Anaerobic vs. Aerobic respiration

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