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Cell Structure and Function
1. 1–100µm
2. Why is there a limit to cell size?
a. Surface-to-volume ratio
b. Distance from surface to center
Cell Size
adult human
tallest trees
chicken egg
frog embryo
most eukaryotic cells
mitochondrionmost bacteria
virus
proteins
atoms
diameter of DNAdouble helix
Prokaryotic—no nucleus, circular DNA, ribosomes
Eukaryotic—larger, nucleus, linear chromosomes, membranous organelles
Cell types
Prokaryotic Cells
Have no membrane-bound organelles
Include true bacteria On earth 3.8 million years Found nearly everywhere
Spores in each breath; intestines
Naturally in soil, air, hot springs
ribosomes
cell wall
plasma membrane
food granule
prokaryoticflagellum
cytoplasm
nucleoid (DNA)
Eukaryotic Cells
Have numerous internal structures
Various types & formsPlants, animals, fungi, protists
Multicellular organisms
flagellum
cytoplasmrough endoplasmicreticulum
ribosome
microtubules
lysosome
mitochondrion
Golgi complex
plasmamembrane
intermediatefilaments
vesicle
smooth endoplasmicreticulum
free ribosomevesicle
nuclear porechromatin (DNA)
nucleolusnuclear envelope
nucleus
chloroplast
central vacuole
rough endoplasmicreticulum
ribosomes
microtubules(part of cytoskeleton)
cell wall
mitochondrion
Golgi complex
plasmamembrane
intermediatefilaments
smooth endoplasmicreticulum
free ribosome
vesicle
nuclear porechromatin
nucleolus
nuclear envelope
nucleus
Eukaryotic Cell Structure
Cytoplasm is the clear, gelatinous fluid inside of a cell
Eukaryotic cell structure
Nucleus is control center of the cell
1. Membrane bound (nuclear envelope)
2. Contains nucleoli; synthesizes ribosomal RNA
3. DNA in chromosomes (DNA and proteins)
nuclear pores
chromatin
nucleolus
nuclear envelope
nuclear pores
nucleus
chromosome
chromatin
Eukaryotic cell structure
Organelles
Endoplasmic reticulum consists of folded membranes attached to the nucleus
Rough ER is site of protein synthesis and protein secretion
0.5 micrometers
smooth endoplasmic reticulum
vesicles
ribosomes
rough endoplasmic reticulum
0.5 micrometers
Eukaryotic Cell Structure
Organelles (cont.)
Ribosomes assemble amino acid into polypeptide chains
• a. Associated with the ER
• b. Composed of RNA and proteins
0.5 micrometers
ribosomes
rough endoplasmic reticulum
0.5 micrometerssmooth endoplasmic reticulum
vesicles
Eukaryotic Cell StructureOrganelles (cont.)
Golgi apparatus are membranous sacs associated with ER
• a. Processing and transport of proteins, lipids
• b. Synthesis and transport of polysaccharides
Golgi complex
vesiclesfrom ER
vesiclesleavingGolgi complex
Eukaryotic Cell Structure
Vacuoles: membrane-bound compartments that are temporary storage of materials
Animal cells do not usually contain vacuoles, if they do they are very small
Plant cells usually use them for water storage
Eukaryotic cell structure
Organelles (cont.)
Lysosomes are Golgi-derived vesicles containing digestive enzymes
Digest excess or worn out organelles, food particles, and engulfed viruses or bacteria
Golgi complex
vesiclesfrom ER
vesiclesleavingGolgi complex
Eukaryotic Cells: Organelles Energy sources for cell activities
Mitochondria provide energy for cellular functions (respiration)
• a. Membrane bound, numerous
• b. Matrix/cristae
• c. Have their own DNA and ribosomes; self-replicate
5 micrometers
Eukaryotic Cells: Organelles Energy sources for cell activities
• Chloroplasts—function in photosynthesis
1) Green—contain chlorophyll pigment
2) Stroma/grana (thylakoid stacks)
3) Have their own DNA and ribosomes; self-replicate
4) Up to 100 per cell
Eukaryotic Cells: Organelles
CytoskeletonInternal infrastructure
Surface structures
extensions of the plasma membrane aid in movement of simple organisms
tubulinsubunit
actinsubunits
subunit
Cytoskeleton
Microtubules-thin hollow cylinders made of protein
Microfilaments- smaller, solid protein fibers
They work together to maintain the shape of the cell
Centrioles
Organelles found in the cells of animals and most protists
Occur in pairs and are made up of microtubules
Play an important role in cell division
Cilia and Flagella
Cilia are short, numerous projections that look like hairs
Flagella are longer projections that move with a whip-like motion
Both are used for locomotion or feeding
Prokaryotes & Eukaryotes
Similarities & differences
Both surrounded by plasma membrane, but very different
Prokaryotes – Archaebacteria and Eubacteria
Eukaryotes – everything else
Plant & Animal Cells
Similarities
Both constructed from eukaryotic cells
Both contain similar organelles
Both surrounded by cell membrane
Plant & Animal Cells
Differences
Plants have• Cell wall – provides strength & rigidity• Have chloroplasts, photosynthetic
Animals have• Other organelle not found in plants
(lysosomes formed from Golgi)• Centrioles, important in cell division
Brief Look at Viruses
Viruses are acellular
Not considered to be living
Cause serious diseases in most organisms