CBS-KNAW Fungal Biodiversity Centre Mariëtte Oosterwegel May 11 th 2015 CBS-KNAW Fungal Biodiversity Centre Strategy 2015-2020 Agriculture Industry Health

CBS-KNAW Fungal Biodiversity Centre

Mariëtte Oosterwegel May 11th 2015

CBS-KNAW Fungal Biodiversity Centre Strategy 2015-2020

Agriculture Industry

Health


0 Management summary and motivation 3

1 Mission, vision, and ambition 5

2 Core activity 1: Research 7

3 Core activity 2: Collection 11

4 Additional Activities 15

5 Strategic Roadmap 20

6 Organizational setup 22

7 Recommendations peer review 25

2

Table of Contents

CBS-KNAW Fungal Biodiversity Centre 3

Motivation: New long term strategy required to maintain international leading position in mycology

Recommendations peer review

Financial pressurePublic pressure for societal relevant

research

New CBS buildingConnections with partners at USP

0


The long term strategy of CBS is based on a model that emphasizes the balance between mission, market, propositions and organization

1

MarketWho are our clients and what

are their needs?

Welke proposities beiden we en met welke strategische doelen?

Mission, vision and ambition

Welke organisatiestructuur past het beste?

PropositionsOrganizationWhat products and services

do we supply?What is needed to support

the propositions?

© Vintura strategy model


Research and the collection are the core activities of CBS

5

2M

POCore activities: Summary

Research Collection

Goal

To enlarge the known fungal biodiversity, identify fungal properties and develop new fungal applications

To collect, preserve and issue fungal biodiversity and related (meta)data

Ambition

CBS does highly innovative mycological research that contributes to the discovery (biodiversity) and

understanding of fungi and solutions to societal challenges

CBS has an encompassing and high quality collection of fungi and related (meta)data that is highly utilized by

public and private parties

Scope

Strategic focus• Novel product discovery• Medical Mycology• Bioinformatics

Functional focus• Agriculture• Health• Industry

Proactive• Strains subject to

publications• Reference strains• Type strains of new

species

Reactive• Type strains of new

species• Multiple strains per

species if relevant

Customers

SocietyGlobal science in general

• CBS Researchers• Academia• Medical Labs

• Public Health Institutes• Reference labs• Industry


CBS research focuses on three functional domains that contribute to the strategic focal points of novel product discovery, medical mycology and bioinformatics

6

2

Core activities: Research

The research focus for CBS distinguishes between an overarching strategic focus on specific, strategically important topics and a functional focus on the general research domains the CBS is specialized in

Strategic focus

Novel product discovery is about identifying fungal species with specific properties that make them potentially useful in drug development, enzyme discovery etc.

Medical mycology is focused on the characterization and early detection of potential harmful fungal pathogens to humans and animals, their fungal properties, dispersal and infection.

Bioinformatics encompasses the generation, storage and analysis of (meta)data on fungal strains to accurately describe fungi, identify patterns and map their (genetic) characteristics.

Functional focus

The functional focus of CBS research is on three domains delimited primarily by the fungal species that present themselves in them (agriculture, health and industry). Where they overlap, existing knowledge and data from one domain can prove useful to research in another.

M

PO

Strategic focus

Functional focus


Health

Medical Mycology


The CBS collection focusses primarily on fungi that have been subject to publishing, reference strains and type strains

7

3

Core activities: Collection - fungi

CBS collection focus

The CBS fungal collection focus is determined primarily by its acquisition focus, defined by both active acquisition (actively pursued by the collection curator) and reactive acquisition (based on material offered to CBS by third parties)

Proactive acquisition of new strainsa) Strains that have been subject to publishing by CBS or third parties

b) Reference strains used in quality control

c) Type strains of new species

Reactive acquisition of new strains (where offered and dependent on capacity)a) Strains of fungal species that are new to the collection or to the known

biodiversity (maximize type strains)b) Multiple strains per species when important to CBS research projects and/or

market demand

Included in focus Not included in focus

Relevant to CBS or third party research Bacteria*

Genome-sequenced strains Non-culturable strains

*Bacteria are not part of the focus of the CBS collection, a number of actions will be initiated to determine the future of the bacterial collection (see strategic roadmap)

M

PO


The CBS fungal collection is continuously enriched with data originating from internal and external research performed with CBS fungi and (meta) data

8

3

Other research institutes:

- Academia- Medical labs- Public health institutes- Reference labs- Industry

CBS collection of fungi and (meta)dataData types collected M/O*

Material, nomenclature, origin, organism, habitat, BSL code, etc.

M

Link to external databases

M

DNA sequence data, including barcodes

M

Yeast physiology M

Protein and metabolites M

Fungal physiology M

Publication M

Morphology descriptions, pictures

O

Data types collected M/O*

Material, nomenclature, origin, organism, habitat, BSL code, etc.

M

Link to external databases

M

DNA sequence data, including barcodes

M

Yeast physiology M

Protein and metabolites O

Fungal physiology O

Publication O

Morphology descriptions, pictures

O

*Must have data (M) = to be actively collected, stored and published if data is available, not generating new data or Optional (O) depending on availability of data

Core activities: Collection - (meta)dataM

PO

Research outcomes: (meta)data

Fungi (Meta)data Fungi (Meta)data

Research outcomes: (meta)data


Health


CBS currently performs additional activities4

Additional activities: propositions

Additional activity Proposition

Identification 1 Identification of fungi, yeasts and bacteria for (commercial) third parties

Contract research 2 Consultancy and contract research for (commercial) third parties*

Reference panels 3 Supplying tailor made panels of reference strains for (commercial) third parties

Events 4 International mycological conferences

Publications5 Editing and publishing of mycological journals

6 Editing and publishing of books

Courses 7 Developing and offering of mycological courses

* Focus on consultancy and contract research that benefits from / is of benefit to the CBS core activities: collection & research

M

PO


Strategic roadmap for core activities

10

5 M

PO

Strategic roadmap Planning Owner

Research

1 Build-up bioinformatics, novel product discovery and medical mycology research groups

Plan: 6/2105Start: 1/2016

Pedro

2 Stimulate synergy between research groups Plan: 4/2015Start: 5/2015

Pedro

3 Increase local brand awareness & collaboration - especially in USP the Uithof Plan: 4/2015Start: 5/2015

Mariëtte

4 Generate new funding opportunities Plan: 4/2015Start: 5/2015

Pedro

5 Develop expertise in patenting / IP 7/2015 Mariëtte

Collection

1 Actively acquire fungi Plan: 4/2105Start: 5/2015

Gerard

2 Enrich fungi collection with data Plan: 6/2105Start: 7/2015

Vincent

3 Decide on bacteria collection 12/2015 Gerard

4 Increase number of fungi issued to third parties Plan: 4/2105Start: 5/2015

Marizeth


Strategic roadmap for additional and overall activities

11

5 M

PO

Strategic roadmap Planning Owner

Additional activities

1 Analyze real contribution margin of additional activities 12/2015 Rob

2 Organize major international meetings in the Netherlands(e.g. ISHAM 2018 and IMC12 2022)

Continuous Management Team

Company wide

1 Increase number of social activities Plan: 4/2105Start: 5/2015

Manon

2 Review number of websites Plan: 4/2105Start: 5/2015

Vincent

3 Increase broader CBS brand awareness Plan: 4/2105Start: 5/2015

Manon

4 Develop criteria for students and interns Plan: 4/2105Start: 5/2015

HR

5 Create long term investment plan for equipment (new / replacement) 12/2015 Ad


ResearchCollection

The defined key performance indicators are linked to the responsible organisational entities

12

6 M

PODirector

Operations

Collection Research

# Pub Fundamental & applied research

# Pub with impact factor > 10

# Pub Discovery Science (new species)

# patents filed

# Pub with impact factor > 9

Earning capacity/group (fte) # Fungi in the collection

# Bacteria in the collection

# Fungi issued to third parties

# Bacteria issued to third parties

Linked sequence data (%)

Critical mass/group (fte)

# Identification assignments

# Reference panels supplied to third parties

# consultancy/innovations research projects

# events

# courses

# journals published

# books published

Core

Additional

= Commercial skills needed. If financially attractive /commercially feasible, these tasks can be centralised


For each of the divisions, the management layers are further detailed

13

6 M

PODirector

Managing Director

Head of Collection

Core activity 1: collection

PI Bio-informatics

PI Novel Product

Discovery2

PI Evolutionary

Phyto-pathology

PI Fungal Physiology

PI Yeast Research

PI Medical Mycology2

ICT Finance

Facility Services

HR

Domestic Services

Technical Services

Media kitchen1

1 Final positioning to be determined2 New research groups3 Associated activities

Board of Directors

MT

PR

Core activity 2: research

Service unit3

Scientific Advisory Board

CBS database3


The peer review committee gave several recommendations for future development

14

7

# Recommendations

1 Renegotiate KNAW funding to match increase in research grant funding

2 Agree with KNAW on changes in financial management systems

3 Retain knowledge base to handle broad diversity of fungi

4 Report on the use of collection, specifying which strains are used most

5 Broaden visibility to stakeholders and society through marketing activities

6 Develop business case and model for Natural Product Discovery Unit

7 Improve access to Biology data and acquire position as knowledge hub

8 Continue active participation in MIRRI, ECCO, IUMS, and IMA

9 Generate funding through global philanthropic organizations

10 Avoid sourcing of IT tools unless cheaper and reconsider BioloMICS tool

11 Specify timelines for the implementation of strategy beyond 2015

12 Establish a clear organogram of reporting lines in the organization

13 Setup internal guidelines for PhD training

14 Appoint mentors to new PhD students

15 Ensure PhD students are enrolled in graduate schools

16 Provide information on new strategies quickly to entire staff


CBS-KNAW Fungal Biodiversity Centre Strategy 2015-2020


Health

Documents

CBS-KNAW Fungal Biodiversity Centre Mariëtte Oosterwegel May 11 th 2015 CBS-KNAW Fungal Biodiversity Centre Strategy 2015-2020 Agriculture Industry Health