Case Studies in Dementia: Alzheimer's, ALS, MS, Parkinson’s,

Schizophrenia & Autismby

Steven W. Hines, N.D., N.E.

Reversing Neurodegenerative

Disease

Case Studies in Dementia:Alzheimer’s, ALS, Parkinson’s, MS,

Schizophrenia & Autismby

Steven W. Hines, ND, NE

Presentation Objectives

• Discuss possible infectious aspects to neurodegeneration.

• Discuss how to test for infections & toxins that may cause neurodegeneration.

• Discuss valuable tools for reversing neurodegenerative disease.

Case Study 1

62-year-old male. Diagnosis: ALS/Guillain Barre Syndrome. Neurology could not agree on diagnosis.

Symptoms: Patient had feeling in his legs but was unable to stand. He was wheelchair bound but had good upper body strength.

Treatment: Patient tested positive for Lyme disease. Administered Rocephin, 1 gram bid for 9 months. Patient became totally quadriplegic as treatment progressed. Administered physical therapy, 3 days per week with muscle stem. Patient took probiotics and antifungals.

Result: Patient fully recovered and went back to work remodeling houses.

Case Study 26-year-old male. Diagnosis: Autistic Spectrum Disorder.

Symptoms: Patient was unable to speak and could not attend school.

Treatment: Grain-free diet, Lyme disease protocol of samento and cumanda. 1 gram fish oil, twice daily.

Result: 30 days later = 80% improvement.

Reference: • Observational study by Hope Wellness Center. 5 of 5

Autism patients were DNA positive for borrelia species.

Case Study 374-year-old female. Diagnosis: Dementia.

Symptoms: Patient was unable to converse, could only make a few sounds and had no reaction other than a blank smile. Suspected neurological chlamydia pneumoniae.

Treatment: Intravenous Azithromycin, 10 days. IV peroxide, daily.EDTA chelation, twice a week (total of 4 treatments).

Result: Patient became totally normal by the end of 10 days.

Reference: • Yamamoto, H., et. al. High prevalence of Chlamydia

pneumoniae antibodies and increased high-sensitive C-reactive protein in patients with vascular dementia. Journal of the American Geriatrics Society. 2005 Apr; 53(4): 583-9.

Case Study 464-year-old female. Diagnosis: Parkinson’s Disease.

Symptoms: Patient was extremely disabled with global tremors, spastic gait, Choreiform Movement Disorder, extreme fatigue, spasticity of speech, and anxiety attacks. Required a walker for mobility.

Note: Patient was previously treated with $250,000 worth of stem cells in Korea. She reports having only short-lived benefit from treatment.

Treatment: Referred patient to a biological dentist. Dentist removed 7-8 root canal teeth, treated numerous cavitations and all metals.

Note: Endotoxins from root canals and cavitations can be transported to the brain through trigeminal nerve. These infections are common among neurological conditions.

Case Study 4, cont.Result: Dramatic improvement after 3-4 months. She and her husband now travel the country in their motorhome. She reverted a few years later to some extent but we were not part of her follow up. We would have given IV antibiotics to treat the systemic aspects of the dental infections, namely treponema denticola.

Note: A number of pathogens are known to inhibit tyrosine hydroxylase enzymes. These pathogens can grossly alter dopamine and serotonin levels. Pathogens include beta strep, toxoplasma and mycobacterium avium complex, to name a few.

References: • Anderson, A., et al. Comprehensive analysis of secondary

dental root canal infections: A combination of culture and culture-independent approaches reveals new insight. PLoS One. 2012; 7(11): e49576.

• Broxmeyer, L. Parkinson's: another look. Medical Hypothesis. 2002; 59(4): 373-77.

Case Study 582-year-old male. Diagnosis: Schizophrenia, dementia,

chronic diarrhea.

Symptoms: Patient suffered from cognitive impairment, nervousness, forgetfulness, lack of attention span, no memory. GI-02 panel showed toxoplasmosis in the gut.

Treatment: Gallium Maltolate, 1.5 grams for 2 days. Alinia, 500 mg with 10 grams of fat bid for 14 days.

Result: Patient was symptom-free from neurological symptoms in 2 days and symptom-free from gut issues in 2 weeks.

Case Study 5, cont.References:

• Chitambar, C.R. Medical applications and toxicities of gallium compounds. International Journal of Environmental Research and Public Health. 2010; 7: 2337-2361.

• Galván-Ramírez Mde. L., et al. Effect of nitaxozanide and pyrimethamine on astrocytes infected by toxoplasma gondii in vitro. Archives of Medical Research. 2013 Aug; 44(6): 415-21.

• Medical News Today. A fifth of schizophrenia cases ‘may be attributable to T. gondii infection’. (2014, Nov 2). http://www.medicalnewstoday.com/articles/284681.php

• Martens, R.J., et al. Chemoprophylactic antimicrobial activity of gallium maltolate against intracellular rhodococcus equi. Journal of Equine Veterinary Science. 2007; 27(8): 341-345.

Case Study 6

60-year-old female. Diagnosis: Dementia/Alzheimer’s.

Symptoms: Patient struggled with extreme cognitive dysfunction.

Treatment: Chelation, twice weekly. IV ozone, 3 times per week for 3 months. Hydration therapy.

Result: 1 year after treatment, the patient was essentially normal.

Note: IV ozone has been shown to normalize nad to nadh ratios, thus helping normalize mitochondrial function.

Case Study 6, cont.References:• Davis, J.L. High iron levels identified in brains of

Alzheimer's patients. WebMD Health News. (2000, Feb. 28). http://www.webmd.com/alzheimers/news/20000228/high-iron- levels-identified-in-brains-of-alzheimers-patients.

• Seymour, D.G., et al. Acute confusional states and dementia in the elderly: the role of dehydration/volume depletion, physical illness and age. Age and Ageing. 1980; 9(3): 137-146.

Case Study 750-year-old male. Diagnosis: Multiple Sclerosis.

Symptoms: Gait disturbance, cognitive dysfunction, extreme fatigue, wheelchair necessary most of the time. Patient tested positive for Lyme disease, bartonella, babesia, mycoplasma, gluten intolerance, and had mercury amalgams, root canals and cavitations.

Treatment: IV silver, ozone, IV Rocephin + DMSO, MGIK drips, Glutathione, Alpha Lipoic Acid, H2O2, HGH, urine vaccine, IV Flagyl, Plaquenil, thyroid, chelation, samento, cumanda, Cholestyramine, antifungals, thiamine injections, crude liver extract, gallbladder/liver flushes and much more.

Result: The patient came in the clinic the first day in a wheelchair and walked out the same day after treating chronic dehydration. After 13 years, patient remains in great health.

Case Study 7, cont.Note: Although not available at the time of his treatment, we now recommend CCSVI treatment for some MS patients.

References: • Breitschwerdt, E.B., et al. Bartonella sp. bacteremia in

patients with neurological and neurocognitive dysfunction. Journal of Clinical Microbiology. 2008 Sep; 46(9): 2856–61.

• Brinar, V.V.; Habek, M. Rare infections mimicking MS. Clinical Neurol Neurosurgery. 2010; 112(7): 625-8.

• Costantini, A., et al. High dose thiamine improves fatigue in multiple sclerosis. BMJ Case Reports. (2013, July 16).

Case Study 7, cont.References, cont.: • Seymour, D.G., et al. Acute confusional states and

dementia in the elderly: the role of dehydration/volume depletion, physical illness and age. Age and Ageing. 1980; 9(3): 137-146.

• Zamboni, P., et al. Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 2009; 80: 392-99.

Resources• Samento and cumanda. Nutramedix. (561) 745-2917.

• Gallium Maltolate. Larry Bernstein. www.gallixa.com.

• Grain-free diet. The Road to Health: Overcoming Chronic Illness through Nutrition by Laura Schroeder & Steve Hines. Hope Wellness Center. (325) 947-5266. info@hopewellness.com.

• GI-02 panel. Diagnostechs. (800) 878-3787.

• Thiamine injections. See Klenner Protocol for MS - most compounders make it.

Resources, cont.

• Alinia. Antiparasitic drug available through most pharmacies. Can be purchased online through Canadian and South American pharmacies under generic label (Daxon). The generic is not as good as the name brand but is about 80% cheaper and has worked well for us so far. We usually dose at 500 mg bid, given with 10 grams of fat per dose for 21 days. It is the most effective treatment for amoebas and protozoa. May need to extended dosage for 3 to 4 months for neurotoxo treatment.

Checklist of causes: Alzheimer’s

Infections may be involved in neurological disease conditions, in addition to other factors. The following are the most

correlative:

Alzheimer's: • Lyme disease• treponema denticola• leptospira• HSV• insulin resistance• gluten enteropathies• iron overload• CCSVI/vascular insufficiency• black mold• dysbiosis• thyroid imbalance

Checklist of causes: Parkinson’s Disease

Infections may be involved in neurological disease conditions, in addition to other factors. The following are the most

correlative:

Parkinson’s: • dental infections (primarily upper left & right cavitations

of wisdom teeth sockets)• beta strep• mycobacterium avium complex• nocardia• iron overload• dysbiosis

Checklist of causes: Lou Gehrig’s Disease

(ALS)Infections may be involved in neurological disease conditions,

in addition to other factors. The following are the most correlative:

ALS: • neurological borrelia• treponema denticola• black mold and other molds (primarily molds growing in

the sinuses and/or environment) • heavy metal toxicity• dysbiosis

Checklist of causes: Autism

Infections may be involved in neurological disease conditions, in addition to other factors. The following are the most

correlative:

Autism: • GMO foods• gluten intolerance• leaky gut• Lyme disease• bartonella• mycoplasma• vaccinations• heavy metal toxicity• candidiasis• dysbiosis

Checklist of causes: Schizophrenia

Infections may be involved in neurological disease conditions, in addition to other factors. The following are the most

correlative:

Schizophrenia: • niacin deficiency• toxoplasmosis

Checklist of causes:Multiple Sclerosis (MS)

Infections may be involved in neurological disease conditions, in addition to other factors. The following are the most

correlative:

Multiple Sclerosis: • Lyme disease• GMO foods• gluten intolerance• leaky gut• dental infections• nickel caps & crowns• CCSVI• thiamine deficiency• candidiasis• TMJ

• mycoplasma• bartonella• babesia• vitamin D

deficiency• dysbiosis• dehydration• sex steroid • hormonal

dysfunction• thyroid imbalance• low aldosterone• low ADH