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Case 3. 30 year old woman Visiting friend from out of province. Found deceased in bed Some ethanol ingestion, but no drug use, reported evening prior History of hypertension, no medications. At autopsy: Cardiomegaly (550 grams) and left ventricular hypertrophy (2.0 cm) - PowerPoint PPT Presentation
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Case 3
• 30 year old woman• Visiting friend from out of province. Found
deceased in bed• Some ethanol ingestion, but no drug use,
reported evening prior • History of hypertension, no medications
• At autopsy:– Cardiomegaly (550 grams) and left ventricular
hypertrophy (2.0 cm)– Arteriolonephrosclerosis
Case 4
• 6 year old boy• Presented to hospital with 2 hours of vomiting• Vtach and hypotension during investigations,
cardiac arrest• One week history occasional headaches and
two day history intermittent chest pain• No known medical or family history
Chromogranin
Inhibin
Synaptophysin
S100
Case 5
• 23 day old infant female• Presented with abnormal respirations and
became unresponsive • Transported to IWK, never regained
consciousness• Approximately 8 hours presentation to death• Normal pregnancy and delivery, previously
healthy
• At autopsy:– Well nourished and normally developed– No injuries– Subarachnoid staining, vascular congestion and
petechial hemorrhages, markedly friable parenchyma
• Neuropathology consultation:– Purulent exudate parieto-occipital region– Perivascular cuffing monocytes and neutrophils,
focal endothelialitis– Gram positive cocci, not paired
• Blood culture (post mortem):– Streptococcus agalactiae, no other growth
• Mother GBS positive on prenatal screening• No antibiotics given at delivery
Case 6
• 32 year old woman• Witnessed sudden collapse• No known medical history