POSTER PRESENTATION Open Access

Cardiac magnetic resonance adenosine perfusionat 3 Tesla is superior to 1.5 Tesla for detection ofrelevant coronary artery stenosisPeter Bernhardt*, Robert Gradinger, Thomas Walcher, Wolfgang Rottbauer

From 2011 SCMR/Euro CMR Joint Scientific SessionsNice, France. 3-6 February 2011

BackgroundCardiac magnetic resonance imaging (CMR) includingadenosine perfusion and late gadolinium enhancement(LGE) at 1.5 Tesla (T) has been established for noninva-sive detection of relevant coronary artery disease (CAD).However, little is known about the potential advantagesof 3.0-T to detect CAD. The aim of our prospectivestudy was to compare a compiled clinical routine CMRprotocol performed at both 1.5-T and 3.0-T in patientswith suspected CAD undergoing coronary x-rayangiography.

MethodsFifty-two patients (62.3 ± 10.2 years) with suspectedCAD referred for coronary x-ray angiography wereincluded into the study. All patients were scanned atboth 1.5-T and 3.0-T including functional imaging, ade-nosine stress and rest perfusion, and LGE imaging.CMR images were analyzed by two blinded readers inconsensus. A significant CAD was diagnosed by quanti-tative coronary analysis. Two thresholds of >50% and>70% stenosis in coronary arteries with a diameter of>2mm were chosen.

ResultsDiagnostic accuracy of the combined analysis of perfu-sion and LGE imaging yielded better values at 1.5-T and3.0-T than the analysis of perfusion images alone. Sensi-tivity and specificity at 3.0-T was superior to 1.5-T indetection of coronary stenoses >50% (0.87 vs. 0.77 and0.91 vs. 0.76) and >70% (0.96 vs. 0.89 and 0.92 vs. 0.80).Area under receiver-operator characteristic (ROC) curvewas higher for detection of coronary stenoses in the left

anterior descending and left circumflex artery at 3.0-Tin comparison to 1.5-T, but not in the right coronaryartery.

ConclusionsThis study showed that CMR at 3.0-T in a routine clini-cal setting is superior to 1.5-T in detection of significantCAD. 3.0-T might become the preferred CMR fieldstrength for evaluation of CAD in clinical practice.

Published: 2 February 2011

doi:10.1186/1532-429X-13-S1-P97Cite this article as: Bernhardt et al.: Cardiac magnetic resonanceadenosine perfusion at 3 Tesla is superior to 1.5 Tesla for detection ofrelevant coronary artery stenosis. Journal of Cardiovascular MagneticResonance 2011 13(Suppl 1):P97.

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University of Ulm, Ulm, Germany

Bernhardt et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):P97http://jcmr-online.com/content/13/S1/P97

© 2011 Bernhardt et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the CreativeCommons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, andreproduction in any medium, provided the original work is properly cited.