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CARBOHYDRATES
The term “carbohydrate” refers to a group of molecules composed of carbon, hydrogen, and oxygen.
There are two groups: Simple carbohydrates (also called “sugars”) Complex carbohydrates
The term “carbohydrate” refers to a group of molecules composed of carbon, hydrogen, and oxygen.
There are two groups: Simple carbohydrates (also called “sugars”) Complex carbohydrates
In fact, they are related: 1. The complex carbohydrates are formed by linking together many simple carbohyrates and2. The simple carbohydrates can be formed by breaking apart the complex carbohydrates
We get carbohydrates in our diets from eatingplants and, to smaller degree from milk and meat.
Simple Carbohydrates:
The simple carbohydrates are the monosaccharides and the disaccharides
Simple Carbohydrates:
The simple carbohydrates are the monosaccharides and the disaccharides
Although there are dozens of known monosaccharides and disaccharides, only a small number are important nutritionally because they are found in our food.
Monosaccharides: All have formula C6H12O6
Glucose (also called “dextrose”) is the most abundant and most important monosaccharide.
Simple Carbohydrates: Monosaccharides
Glucose (also called “dextrose”) is the most abundant and most important monosaccharide.
All green plants produce glucose from carbon dioxide, water, and sunlight (energy) Gives food a sweet taste
Glucose is the primary “fuel molecule” our cells use to produce energy soIt is the sugar carried around the body in the blood
Simple Carbohydrates: Monosaccharides
Fructose (also called “levulose” or “fruit sugar”) is also very sweet
Simple Carbohydrates: Monosaccharides
Fructose (also called “levulose” or “fruit sugar”) is also very sweet
Occurs naturally in fruits, vegetables,honey, and corn syrup.
Some cells can use fructose as a fuel molecule, but most cells convert it to glucose instead
Simple Carbohydrates: Monosaccharides
Galactose - rarely found alone in natureUsually combined with glucose
Simple Carbohydrates: Monosaccharides
Galactose - rarely found alone in natureUsually combined with glucose
Found in milk
Cells convert galactose to glucose for energyMay be part of cell membranes
Simple Carbohydrates: Monosaccharides
Simple Carbohydrates: Disaccharides
Disaccharides are two monosaccharides linked together
Simple Carbohydrates: Disaccharides
Disaccharides are two monosaccharides linked together
Three disaccharides are dietarily important:
Sucrose
Lactose
Maltose
All have formula C12H22O11
Simple Carbohydrates: Disaccharides
Sucrose = glucose + fructose
Found in sugarcane, sugarbeets
“Table Sugar” – only sweetener that can be called “sugar” on food labels in United States
Simple Carbohydrates: Disaccharides
Lactose = glucose + galactose
“Milk Sugar”
Simple Carbohydrates: Disaccharides
Maltose = glucose + glucose
Found in partially digested starch and in germinating cereal grains
Chains of two or more monosaccharides
Oligosaccharides = shorter chains
Polysaccharides = longer chains
Complex Carbohydrates
Complex Carbohydrates: Oligosaccharides
Consist of 3-10 monosaccharides
Found in legumes, milkForms receptors on many cell membranes
Not digestible by humans = fiber
May be added to food: inulin oligofructose raffinose maltotriose
Starch: How plants store energy Found in grains, legumes, and tubers
Long chains of glucose units:
Amylose—straight chains
Amylopectin—branched chains
Complex Carbohydrates: Polysaccharides
Glycogen How animals (including humans) store energy Found in meat, liver
Long, branching chains of glucose units:
Formed in liver and muscle when blood glucose levels are high
Can be broken down to provide glucose when blood glucose levels get low
Complex Carbohydrates: Polysaccharides
Cellulose
Complex Carbohydrates: Polysaccharides
Indigestible chains of monosaccharides = “fiber” - speeds up gastrointestinal movement - increases fecal mass - slows breakdown of starch - slows absorption of glucose
Found in all plants,
“Functional” fiber: isolated and added to foods
Can be use as a supplement
Other forms of fiber
Complex Carbohydrates: Polysaccharides
= Indigestible chains of monosaccharides Pectins Gums Lignans Beta glucans Chitins
Found in all plants,
“Functional” fiber: isolated and added to foods
Can be use as a supplement
Complex Carbohydrates
Dietary fiber:
Possible role in weight control
Better control of blood glucose
Reduced risk of heart disease
Healthier gastrointestinal functioning
Negative effects of excess fiber
Increased water consumption
Can bind small amounts of minerals
Complex Carbohydrates:
Complex carbohydrates (amylose, amylopectin) broken down to form disaccharides and monosaccharides:
Mouth: Salivary amylase begins digestion
Stomach: No carbohydrate digestion
Small intestine: Pancreatic amylase finishes digestion
Carbohydrate Digestion:
Disaccharides (sucrose, maltose, lactose) broken down to form monosaccharides:
Small intestine: Pancreatic enzymes
Enzymes from intestinal cells (sucrase, maltase, lactase)
Carbohydrate Digestion:
These enzymes are highly specific
For example: - Amylase digests amylose but not amylopectin - Lactase digests lactose but not maltose or sucrose - Maltase digests maltose but not lactose or sucrose - Sucrase digests sucrose but not maltose or lactose
Remember: Some carbohydrates can not be digested; fiber & “resistant” starch
Carbohydrate Digestion:
Monosaccharides are absorbed from the small intestine
Carbohydrate Absorption:
Monosaccharides are absorbed from the small intestine
and carried by the blood to the liver
Carbohydrate Absorption:
Monosaccharides are absorbed from the small intestine
and carried by the blood to the liver
Carbohydrate Absorption:
Liver: Converts other monsaccharides to glucose
Stores excess glucose as glycogen
Monosaccharides are absorbed from the small intestine
and carried by the blood to the liver
Carbohydrate Absorption:
Liver: Converts other monsaccharides to glucose
Stores excess glucose as glycogen
Liver: Breaks down glycogen to release glucose back into theblood when needed.
Glucose is our primary fuel source soIt is important to maintain normal blood glucose levels andIt is important for glucose to get from the blood into cells
Carbohydrate Metabolism:
Glucose is our primary fuel source soIt is important to maintain normal blood glucose levels andIt is important for glucose to get from the blood into cells
These processes are primarily regulated by two hormones Insulin GlucagonBoth are secreted by the pancreatic islets
Carbohydrate Metabolism:
Carbohydrate Metabolism:
Insulin promotes:
(i) Energy storage
glucose glycogen (glycogenesis)
(ii) Protein synthesis
glucose amino acids protein
(iii) Fat synthesis
glucose fatty acids triglycerides(fat)
Carbohydrate Metabolism:
Carbohydrate Metabolism: Disorders
Normal Blood Glucose: 70-110 mg/100 ml of blood
Persistent high blood glucose levels = Hyperglycemia Insufficient insulin >125 mg/100 ml
Too much glucagon Most common cause = diabetes mellitus
Carbohydrate Metabolism: Disorders
Normal Blood Glucose: 70-110 mg/100 ml of blood
Persistent high blood glucose levels = Hyperglycemia Insufficient insulin >125 mg/100 ml
Too much glucagon Most common cause = diabetes mellitus
Persistent low blood glucose levels = Hypoglycemia Too much insulin <50 mg/100 ml
Insufficient glucagon Most common causes = insulin overdose in diabetes starvation
strenuous exercise
Carbohydrate Metabolism: Disorders
Normal Blood Glucose: 70-110 mg/100 ml of blood
Diabetes Mellitus:
Glucose unable to enter cells
so
Blood glucose levels rise (hyperglycemia)
Complications: Hypertension Heart damage Kidney damage Nerve damage Blood vessel damage Eye damage
Carbohydrate Metabolism: Disorders
Diabetes mellitus:
Type 1 or “insulin dependent” diabetes: Lack of insulin production
Type 2 or “insulin independent” diabetes: Cells are resistant to insulin
Carbohydrate Metabolism: Disorders
Diabetes mellitus:
Type 1 or “insulin dependent” diabetes: Lack of insulin production
Type 2 or “insulin independent” diabetes: Cells are resistant to insulin
Usually present as “prediabetes” first
Gestational diabetes: occurs during pregnancy
Carbohydrate Metabolism: Disorders
Diabetes mellitus:
Best prevention:
Healthful diet
Regular exercise
Healthy weight
Don’t smoke
Monitor blood sugar if you have genetic predisposition
Carbohydrate Metabolism: Disorders
Recommended carbohydrate intake:
Recommended Daily Allowance = 130 grams per day
Acceptable Macronutrient Distribution Range = 45–65% of calories
Carbohydrates:
Recommended carbohydrate intake: Recommended Daily Allowance = 130 grams per day Acceptable Macronutrient Distribution Range = 45–65% of calories
Choose carbohydrates wisely: fiber-rich fruits vegetables whole grains high-fiber cereal Because:
Not all carbohydrate sources have the same effect on blood glucose levels
Carbohydrates:
Carbohydrates:
Each type of food has a glycemic index which measures its effects on blood sugar levels.
Carbohydrates:
Each type of food has a glycemic index which measures its effects on blood sugar levels.
Carbohydrates that break down quickly during digestion and release glucose rapidly for absorption into the bloodstream have a high glycemic index
Carbohydrates:
Each type of food has a glycemic index which measures its effects on blood sugar levels.
Carbohydrates that break down quickly during digestion and release glucose rapidly for absorption into the bloodstream have a high glycemic index
Carbohydrates that break down more slowly, releasing glucose more gradually for absorption into the bloodstream, have a low glycemic index.
Low glycemic index: Most vegetables, fruits, legumes,(55 or less) whole grains, nuts, milk, citrus juices, foods low in carbohydrates Moderate glycemic index: Whole wheat products, honey, (56 to 69) brown or basmati rice, bran, baked potato, sweet potato
High glycemic index: White bread, white rice, breakfast(70 and above) cereals, waffles, chips, candy, table sugar
(Pure glucose: glycemic index = 100)
Carbohydrates:
Moderating sugar intake: Choose food with lower glycemic index
Use less added sugarLimit soft drinks, sugary cereals, and candyChoose fresh fruits or those canned in water or juice
Carbohydrates:
Nutritive sweeteners
Natural sugars
Sugar alcohols
Non-nutritive sweeteners
Saccharin
Aspartame
Acesulfame K
Sucralose
Carbohydrates: Natural and Artificial Sweeteners
Let’s move on to the lipids next