ENHANCED CHALLENGE MANAGEMENT

Providing Enhanced Challenge ManagementLivestock are exposed to a variety of potentially harmful pathogens including bacteria and fungus. The toxins produced by these microorganisms are a leading cause of enteric disease. Pathogenic bacteria produce powerful biotoxins that can be 100,000 TIMES more toxic than fungal toxins found in grain. Protecting your animals from disease requires effectively managing challenges from the broadest spectrum of biotoxins that reduce health and performance.

2

Pathogenic bacteria

produce powerful biotoxins

3

Mucus and epithelial cells

are the first line of defense against harmful pathogens

and biotoxins

4

Intestinal Health Leads to Improved Performance A healthy intestinal environment does more that just aid in the digestion and absorption of nutrients. The mucus and epithelial cells that line the small intestine form a barrier to the external environment and are the first line of defense against harmful pathogens and biotoxins. A disruption in a balanced intestinal environment can result in an overgrowth of pathogenic bacteria and lead to disease.

5

Biotoxins Cause DiseaseEnteric disease is commonly caused by bacterial infections from Clostridium perfringens, E. coli, and Salmonella sp. Bacteria produce powerful biotoxins that damage the integrity and function of the intestinal barrier. These biotoxins cause inflammation, diarrhea, and mal-absorption that result in less gain, higher feed conversion, and reduced performance. Dietary fungal toxins intensify these effects and further reduce animal performance.

6

7

Proven Pathogen Protection Backed by ResearchOnly Calibrin-Z is proven in over 70 clinical studies to reduce the effects from the broadest spectrum of biotoxins that cause disease:

Clostridium perfringens E. coli Salmonella These harmful biotoxins represent a chemically diverse range of toxin molecules that are effectively bound by the activated particles contained within Calibrin-Z.

Vibrio parahaemolyticus Mycotoxins Gossypol

8

9

Activated Particles Protect the Intestinal BarrierCalibrin-Z works in the lumen and chemically bonds with toxin molecules to prevent intestinal damage. It is made using a proprietary surface activation technology that increases hydrogen, electrostatic, and hydrophobic bonding with diverse molecular structures. Amlan utilizes technology that has been developed over 75 years that advances material science beyond the capabilities of companies that merely source mineral adsorbents.

10

Activated Calibrin-Z particle

11

Calibrin-Z particle bonding biotoxins

12

Calibrin-Z is the leader in enhanced challenge management of the broadest spectrum of biotoxins. By protecting the integrity and healthy function of the intestinal environment, Calibrin-Z allows your animals to reach their peak performance.

13

410 N. Michigan Avenue, Suite 400 | Chicago, Illinois 60611, U.S.A. www.amlan.com | +312-321-1887 | info@amlan.com

MADE IN U.S.A.

©2015, Amlan International 10-2015