1

C U R R I C U L U M V I T A E

RAVINDRA L. MEHTA Professor of Clinical Medicine

University of California, San Diego Medical Center Tel: (619) 543-7310 Department of Medicine, Division of Nephrology Fax: (619) 543-7420 200 West Arbor Drive #8342 E-Mail: rmehta@ucsd.edu San Diego, CA 92103 Education M.B.B.S. 1976 Guru Nanak Dev University, Amritsar, India M.D. - Internal Medicine 1979 Post Graduate Institute of Medical Education and Research -

Chandigarh, India D.M. - Nephrology 1981 Post Graduate Institute of Medical Education and Research -

Chandigarh, India M.N.A.M.S. - Nephrology 1981 National Academy of Medical Sciences - New Delhi, India Certification E.C.F.M.G. 1979 Educational Commission for Foreign Medical Graduates V.Q.E. 1979 Visa Qualifying Examination F.L.E.X. 1982 Federation Licensing Examination 1986 American Board of Internal Medicine 1988 American Board of Internal Medicine: Nephrology Medical Licensure 1976 Punjab State Medical Association, India 1985 New York State, License No# 161106 1990 California Medical License No. A48361 Honors 1978 Rotary International Foundation Award for Group Study 1984 - 1986 National Kidney Foundation Fellow 1986 - 1987 Boswell Fellowship, University of Rochester 1991 Fellow, American College of Physicians 1991 Fellow, Indian Society of Nephrology 1991, 92, 94, 96, 2001, 2002 Graduating Housestaff Teaching Award UCSD Medical Center, Department of Medicine 2002 UCSD Medical Center Physician of the Year 2003 UCSD School of Medicine Faculty Award for Excellence in Teaching 2005 Fellow, American Society of Nephrology 2006 Member, Western Association of Physicians

Appointments 1975-1976 Intern, V.J. Hospital (Guru Nanak Dev University), Amritsar, India 1976-1979 Resident in Internal Medicine, Post Graduate Institute of Medical Education and Research,

Chandigarh, India 1979-1981 Fellow in Nephrology, Post Graduate Institute of Medical Education and Research,

Chandigarh, India 1981-1982 Chief Resident in Internal Medicine, Post Graduate Institute of Medical Education and

Research, Chandigarh, India

Ravindra L. Mehta

1982 Resident In Internal Medicine, St. Barnabas Medical Center, Livingston, New Jersey 1982-1983 Clinical Fellow in Nephrology, Strong Memorial Hospital, University of Rochester 1983-1984 Instructor and Research Fellow in Nephrology, University of Rochester Medical Center,

New York 1984-1986 Senior Instructor, Department of Medicine, University of Rochester Medical Center, New

York 1986-1988 Assistant Professor of Medicine, Nephrology Unit, Department of Medicine, University of

Rochester Medical Center, Rochester, New York 1988-1994 Assistant Professor of Medicine in Residence, Department of Medicine, Division of

Nephrology, University of California, San Diego - UCSD Medical Center 1994-2000 Associate Professor of Medicine in Residence, Department of Medicine, Division of

Nephrology, University of California, San Diego - UCSD Medical Center 2000-Present Professor of Clinical Medicine, Department of Medicine, Division of Nephrology,

University of California, San Diego - UCSD Medical Center Administrative Appointments 1989-Present Director, CRRT Program - UCSD Medical Center 1990-1998 Associate Director, Dialysis Programs, UCSD Medical Center 1990-1998 Co-Director, Peritoneal Dialysis Program, UCSD Medical Center 1990-Present Member, Hemodialysis & Transplant Committee - UCSD Medical Center 1991-1992 Course Director, Renal Pathophysiology Section, SOM 208, UCSD 1992-1993 Member, UCSD SOM Graduate Medical Education Committee 1994-1998 Member, Department of Medicine Committee on Academic Promotions 1995-1998 Department of Medicine Representative to Academic Senate 1995-1999 Chair, Division of Nephrology Quality Assurance Committee 1996-Present Member, UCSD Critical Care Committee 1998-2001 Member, UCSD Pharmacy and Therapeutics Committee 1998-2000 Chair, UCSD Pharmacy and Therapeutics Nutrition Subcommittee 1998-Present Director, Clinical Nephrology and Dialysis Programs, UCSD Medical Center 1999-Present Assistant Director, General Clinical Research Center, UCSD Medical Center 2000-2004 Member, UCSD SOM Nominating Committee 2001-2002 Chair, Development Committee, Master of Advanced Studies in Clinical Research 2001-2004 Member, UCSD SOM Faculty Council 2001-Present Director, Clinical Research Enhancement through Supplemental Training Program 2001-Present Member, UCSD Clinical Investigation Institute Brainstorming Group 2003-2005 Member, Patient Satisfaction Steering Committee, UCSD Healthcare 2003-Present Associate Chair for Clinical Affairs, UCSD Department of Medicine 2003-Present Member, UCSD Medical Group Board of Governors 2003-Present Co-Director, Quality/Patient Satisfaction Task Force, UCSD Med Grp Board of Governors 2003-Present Member, Professional Standards Committee, UCSD Medical Group 2003-Present Member, Finance Committee, UCSD Department of Medicine 2003-Present Member, Information Technology Steering Committee, UCSD Healthcare Patents Mehta RL, Ward DM: Continuous Hemodialysis using Citrate Filed October 31, 1989 - Serial No# 07/429,397 Administratively Issued - March, 1991 Memberships

Ravindra L. Mehta

American College of Physicians American Society for Artificial Internal Organs American Society of Nephrology Association of Clinical Research Training Program

(K30) Directors Association for Patient Oriented Research California Medical Association Indian Society of Nephrology

International Society of Nephrology Commission on Acute Renal Failure

Int’l Society of Artificial Internal Organs International Society of Nephrology National Kidney Foundation National Academy of Medical Sciences,

New Delhi, India Society of Critical Care Medicine

Advisory Boards/Task Forces/Committees

1986-1988 Medical Advisory Board, National Kidney Foundation of Upstate New York

1990-1991 Medical Advisory Board Member National Kidney Foundation of Southern California 1995-2001 U.S. Leader, International Society of Nephrology Disaster Relief Task Force

1998-2000 Clinical Science Committee, American Society of Nephrology

1999 Clinical Practice Guideline on Initiation to and Withdrawal from Dialysis, Renal Physicians’ Association and American Society of Nephrology

1999-2000 Planning Committee, Workshop on Design Issues for Clinical Trials in Acute Renal Failure, National Institute of Diabetes and Digestive and Kidney Diseases

1999-Present Postgraduate Education Committee, American Society of Nephrology

2000-Present Acute Dialysis Quality Initiative

2001-Present Dialysis Advisory Group, American Society of Nephrology

2002 Kidney Disease Clinical Trials Task Force, American Society of Nephrology and National Institute of Diabetes and Digestive and Kidney Diseases

2002-2004 Vice-Chair, National Kidney Foundation Clinical Research Review Committee

2002-Present Acute Renal Failure Advisory Group, American Society of Nephrology

2003 Working Group on Trauma Research, National Institutes of Health and Dept. of Defense

2003-Present Director, Acute Kidney Injury Commission, International Society of Nephrology

2003-Present American Society of Nephrology/National Kidney Foundation Task Force on Research Funding

2004-Present Chair, National Kidney Foundation Clinical Research Review Committee

2005-Present Member, Acute Kidney Injury Network (AKIN) and Chair, Organizing Committee

2005-Present Member, National Kidney Foundation KDOQI Advisory Committee

Grant Reviews

2000 National Institute of Diabetes and Digestive and Kidney Diseases

2000 National Medical Research Council of Singapore

2001 National Institutes of Health - K23/K24/K25 Grants

2002 National Heart, Lung, and Blood Institute

Ravindra L. Mehta

2003 National Institute of Diabetes and Digestive and Kidney Diseases

2004 National Institutes of Health - Pathobiology of Kidney Disease Scientific Review Group

Editorial Service

1999-Present Member of Editorial Board, Advances in Renal Replacement Therapy

1999-Present Section Editor, Blood Purification

2001-Present Member of Editorial Board, Journal of the American Society of Nephrology.

Reviewer for Advances in Renal Replacement Therapy, American Journal of Kidney Diseases, American Society for Artificial Internal Organs, Blood Purification, Clinical Nephrology, Critical Care Medicine, Hemodialysis International, Journal of the American Society of Nephrology, Kidney International, Medical Principles and Practice, Nephrology Dialysis Transplantation, New England Journal of Medicine, Transplantation

Individual Student Instructional Activities Past Five Years

Junior Faculty 1999-2002 Scott Mullaney, M.D. (K23 Research Advisor) 1999 Vijaya Pratha, M.D. (N-CLAM Research/Career Mentor) 2000 Asad Bashey, M.D. (N-CLAM Research/Career Mentor) 2001-2003 Scott Letendre, M.D. (CREST Research/Career Mentor) 2001-2003 Polly Moore, Ph.D. (CREST Research/Career Mentor) 2003-2006 Simerjot Jassal,M.D. (CREST Research/Career Mentor) 2004-2006 Linda Awdishu, PharmD (CREST Research/Career Mentor) 2006-Present Prasanthi Ramanujam, M.D. (CREST Research/Career Mentor) 2007-Present Ayesha Sherzai MD (CREST Research/Career Mentor) Researchers at Other Institutions 2000 H.S. Kohli, M.D. (Advisor, International Society of Nephrology Fellowship) 2000 Ashwani Gupta, M.D. (Advisor, Visiting Fellowship) 2000-2001 Neesh Pannu, M.D. (Research Projects Co-Advisor) 2002-2004 Christian Weyer, M.D. (CREST Research/Career Mentor) 2003-2004 Elena Kirpicheva, M.D. (CREST Research/Career Mentor) Postdoctoral Fellows 1999-2001 Thawee Chanchairujira, M.D. (Research Advisor) 2000-2001 Omar Abdeen, M.D. (Research Advisor) 2000-2001 Amit Sharma, M.D. (Research Advisor) 2001-2002 G. Chad Asher, M.D. (Research Advisor) 2006-2007 Shamik Shah, M.D. (Research Advisor) 2006-Present Roy Mathew, M.D. (Research Advisor) 2007- Present Josee Bouchard MD (Research Advisor) 2007-Present Nitin Khosla MD (Research Advisor) Medicine Residents 1998-2000 Madhav Goyal, M.D. (Research Project Co-Advisor) 2003 Ravi Ajmera, M.D. (Research Project Advisor) 2003 Frank Liu, M.D. (Research Project Advisor)

Ravindra L. Mehta

Publications Articles

1. Chugh KS, Malik GH, Singhal PC, Malik H, Chaudhary N, Mehta RL et al: Renal insufficiency following radiocontrast agents - a prospective study. Ind J Rad 35(2):71-76, 1981

2. Sharma KS, Singh S, Mehta RL: Fatal poisoning with methyl isothiocyanate. Br Med J 283:18-19, 1981

3. Chugh KS, Bhoopal R, Sakhuja V, Malik GH, Choudhary N, Chabra S, Mehta RL, et al: Diagnostic

indices in acute renal failure. Ind J Med Res 73:101-105, 1981

4. Singhal PC, Kher VK, Chall GI, Mehta RL, et al: Conservative vs surgical management of septic abortion with renal failure. Int J Gynaecol Obstet 20(3):189-194, 1982

5. Mehta RL, Ganguly NK, Sehgal S, et al: Circulating Immune Complexes in glomerulonephritis with

special reference to minimal change disease. Ind J Med Res 77:96-106, 1983

6. Chugh KS, Pal Y, Chakravarty RN, Datta BN, Mehta RL et al: Acute renal failure following poisonous snakebite. Am J Kidney Dis 4:30-38, 1984

7. Mehta RL, Takahashi H, Rudick R, Knutson DW: Binding and catabolism of aggregated

immunoglobulins containing C3b by U937 cells. J Immunol 136:1765-1771, 1986

8. Stephenson TF, McCabe JF, Svoboda JJ, Balaji MR, Feinstein MJ, Mehta RL: Renal arteriovenous fistula developing in subacute bacterial endocarditis. New York State J of Med 89:530-532, 1989

9. Mehta RL, Scott G, Sloand JA, Francis CW: Skin necrosis associated with acquired protein C deficiency

in patients with renal failure and calciphylaxis. Am J of Med 88:252-257, 1990

10. Mehta RL, McDonald BR, Aguilar MM, Ward DM: Regional citrate anticoagulation for continuous arteriovenous hemodialysis (CAVHD) in critically ill patients. Kidney Int 38:926-981, 1990

11. Mehta RL: Dialysis Clinic: Calciphylaxis. Semin Dial 3(2):132-133, 1990

12. McDonald BR, Kirmani S, Vasquez M, Mehta RL: Acute renal failure associated with the use of

intraperitoneal carboplatin: A report of two cases and review of the literature. Am J of Med 90:386-391, 1991

13. Ashton DN, Mehta RL, Ward DM, McDonald BR, Aguilar MM: Recent advances in continuous renal

replacement therapy: Citrate anticoagulated continuous arteriovenous hemodialysis. ANNA J 18(3):263-267, 1991

14. Mehta RL, McDonald BR, Ward DM: Regional citrate anticoagulation for continuous arteriovenous

hemodialysis (CAVHD): An update after 12 months. Contrib Nephrol 93:210-214, 1991

15. McDonald BR, Mehta RL: Decreased mortality in patients with Acute Renal Failure (ARF) undergoing Continuous Arteriovenous Hemodialysis. Contrib Nephrol 93:51-56, 1991

16. Mehta RL, Brown A, Kennedy B, Ziegler M: Catecholamine Removal Across Polyacrylonitrile (PAN)

Hemofilters. J Am Soc Nephrol 2:338, 1991

17. Mehta RL, Dobos G, Ward DM: Anticoagulation in Continuous Renal Replacement Procedures. Semin Dial 5:61-68, 1992

18. Mehta RL: Anticoagulation in severely ill patients treated with continuous hemofiltration. Nefrologia

12(14):287-294, 1992

19. Lenert P, Mehta RL, Zanetti M: Synthetic peptides of human CD4 enhance binding of Ig to monocyte/macrophage cells. I. Characterization and mapping studies. J Immunol 148:1759-1763, 1992

Ravindra L. Mehta

20. Mehta RL: Continuous Hemofiltration/Dialysis: Current Status and Future Directions. Nefrologia 12:276-286, 1992

21. Ward DM, Mehta RL: Extracorporeal management of acute renal failure patients at high risk of bleeding.

Kidney Int 43 suppl 41:S232-S244, 1993

22. Levin A, Goldstein MF, Mehta RL: Mathematical formulation to help identify the patient at risk of ischemic tissue necrosis. A potentially lethal complication of chronic renal failure. Am J of Nephrol 13(6):448-453, 1993

23. Mehta RL: Renal Replacement Therapy for ARF: Matching the method to the patient. Semin Dial

6:253-259, 1993

24. Novotny WF, Maffi T, Mehta RL, Miler PG: Identification of novel heparin-releasable proteins, as well as the cytokines midkine and pleiotrophin, in human postheparin plasma. Arterioscler Thromb 13(12):1798-1805, 1993

25. Mehta RL: Therapeutic Alternatives for Renal Replacement for Acute Renal Failure in Critically Ill

Patients. Semin Nephrol 14(1):64-82, 1994

26. Monson PT, Mehta RL: Nutrition in Acute Renal Failure: A reappraisal for the 1990's. J of Renal Nutrition 4(2):58-77, 1994

27. Mehta RL: Anticoagulation during Continuous Renal Replacement Therapy. ASAIO J 40(4):931-935,

1994

28. Kaplan R, Mehta RL: Outcome Measurement in Kidney Disease. Blood Purification 12:20-29, 1994

29. Mehta RL, Lenart P, Zanetti M: Synthetic peptides of human CD4 enhance binding of immunoglobulin to monocyte/macrophage cells. II. Mechanisms of enhancement. Cell Immunol 156:146-154, 1994

30. Sloand JA, Mehta RL, Schmer G, Rosenfeld SI: Influence of C1q on Human Platelet - Immune Complex

Interaction. Clin Immunol Immunopathol 76(2): 127-134, 1995

31. Jabara AE, Mehta RL: Determination of Fluid Shifts during Chronic Hemodialysis using Bioimpedance Spectroscopy and an In-Line Hematocrit Monitor. ASAIO J 41(3):M682-M687, 1995

32. Mehta RL: Modalities of Dialysis for Acute Renal Failure. Semin Dial 9(6):469-475, 1996

33. Bellomo R, Ronco C, Mehta RL: Nomenclature for Continuous Renal Replacement Therapies. Am J

Kidney Dis 28(5):S2-7, 1996

34. Mehta RL: Acute Renal Failure in the Intensive Care Unit: Which Outcomes Should we Measure? Am J Kidney Dis 28(5):S74-80, 1996

35. Mehta RL: Anticoagulation Strategies for Continuous Renal Replacement Therapies: What Works? Am

J Kidney Dis 28(5):S8-14, 1996

36. Mehta RL, Martin RK: Initiating and Implementing a Continuous Renal Replacement Therapy Program: Requirements and Guidelines. Semin Dial 9(2):80-87, 1996

37. Mehta RL: Fluid Management in Continuous Renal Replacement Therapy. Semin Dial (2):140-144,

1996

38. Monson P, Mehta RL: Nutritional Considerations in Continuous Replacement Therapy. Semin Dial 9(2):152-160, 1996

39. Mehta RL: Continuous Renal Replacement Therapies in the Acute Renal Failure Setting: Current

Concepts. Adv Ren Replace Ther 4(2) Suppl 1:81-92, 1997

Ravindra L. Mehta

40. DuBose TD, Mehta RL: Acute Renal Failure in the 21st Century: Recommendations for Management and Outcomes Assessment. Am J Kidney Dis 29(5):793-799, 1997

41. Jaeger JQ, Mehta RL: Assessment of Dry Weight in Hemodialysis: An Overview. J Am Soc Nephrol

10(2):392-403, 1999

42. Jaeger JQ, Mehta RL: Dry Weight and Body Composition in Hemodialysis: A Proposal for an Index of Fluid Removal. Semin Dial 12(3):164-174, 1999

43. Jung B, Blake PG, Mehta RL, Mendelssohn DC: Attitudes of Canadian Nephrologists toward Dialysis

and Modality Selection. Perit Dial Int 19(3):263-8, 1999

44. Mehta RL, Letteri JM for the National Kidney Foundation Council on Dialysis: Current Status of Renal Replacement Therapy for Acute Renal Failure: A Survey of US Nephrologists. Am J Nephrol 19(3):377-82, 1999

45. Mendelssohn DC, Mullaney SR, Jung B, Blake PG, Mehta RL: What do American Nephrologists Think

about Dialysis Modality Selection? Am J Kidney Dis 37(1):22-29, 2001

46. Mehta RL: Indications for Dialysis in the ICU: Renal Replacement vs. Renal Support. Blood Purif 19(2):227-232, 2001

47. Ronco C, Kellum J, Mehta RL: Acute Dialysis Quality Initiative. Blood Purif 19(2):222-226, 2001 48. Ronco C, Kellum JA, Mehta R: Acute Dialysis Quality Initiative (ADQI). Nephrol Dial Transplant. 2001

Aug;16(8):1555-8.

47. Mehta RL, McDonald B, Gabbai F, Pahl M, Pascual MT, Farkas A, Kaplan RF: A Randomized Clinical Trial of Continuous vs. Intermittent Dialysis for Acute Renal Failure. Kidney Int 60(3):1154-63, 2001

48. Mehta RL: Fluid management in CRRT. Contrib Nephrol (132):335-348, 2001

49. Kellum JA, Mehta RL, Ronco C: Acute dialysis quality initiative (ADQI). Contrib Nephrol (132):258-

265, 2001

50. Sharma A, Hermann DD, Mehta RL: Clinical benefit and approach of ultrafiltration in acute heart failure. Cardiology 96(3-4):144-154, 2001

51. Chanchairujira T, Mehta RL: Assessing fluid change in hemodialysis: whole body versus sum of

segmental bioimpedance spectroscopy. Kidney Int 60(6)2337-2342, 2001

52. Mehta RL: Acid-Base and Electrolyte Management in Continuous Renal Replacement Therapy. Blood Purif 20(3):262-268, 2002

53. Stange J, Hassanein TI, Mehta R, Mitzner SR, Bartlett RH: The Molecular Adsorbents Recycling System

as a Liver Support System Based on Albumin Dialysis: A Summary of Preclinical Investigations, Prospective, Randomized, Controlled Clinical Trial, and Clinical Experience from 19 Centers. Artif Organs 26(2):103-110, 2002

54. Pannu N, Mehta RL: Mechanical ventilation and renal function: an area for concern? Am J Kidney Dis

39(3):616-324, 2002

55. Arbab-Zadeh A, Mehta RL, Ziegler TW, Oglevie SB, Mullaney S, Mahmud E, Demaria AN, Bhargava V: Hemodialysis access assessment with intravascular ultrasound. Am J Kidney Dis. 2002 Apr;39(4):813-823.

58. Abdeen O, Mehta RL: Dialysis modalities in the intensive care unit. Crit Care Clin 2002 Apr;18(2):223-

Ravindra L. Mehta

47. Review 56. Mehta RL, Pascual MT, Gruta CG, Zhuang S, Chertow GM, for the PICARD Study Group: Refining

Predictive Models in Critically Ill Patients with Acute Renal Failure. J Am Soc Nephrol 2002 May;13(5):1350-1357

57. Goyal M, Mehta RL, Schneiderman LJ, Sehgal AR. Economic and health consequences of selling a

kidney in India. JAMA 2002 Oct 2;288(13):1589-1593 58. Mehta RL, McDonald B, Gabbai F, Pahl M, Farkas A, Pascual MT, Zhuang S, Kaplan RM, Chertow

GM. Nephrology consultation in acute renal failure: does timing matter? Am J Med. 2002 Oct 15;113(6):456-461

59. Kellum JA, Mehta RL, Angus DC, Palevsky P, Ronco C, for the ADQI Workgroup: The First

International Consensus Conference on Continuous Renal Replacement Therapy. Kidney Int 2002 Nov;62(5):1855-1863

60. Mehta RL, Pascual MT, Soroko S, Chertow GM. Diuretics, mortality, and nonrecovery of renal function

in acute renal failure. JAMA 2002 Nov 27;288(20):2547-2553 61. Mehta RL, Clark WC, Schetz M. Techniques for assessing and achieving fluid balance in acute renal

failure. Curr Opin Crit Care 2002 Dec;8(6):535-543 62. Kellum JA, Palevsky P, Mehta R, Bellomo R, Ronco C. Acute Dialysis Quality Initiative: Methodology.

Curr Opin Crit Care 2002 Dec;8(6)500-501 63. Ronco C, Kellum JA, Mehta R. Acute Dialysis Quality Initiative II: the New York Conference. Curr

Opin Crit Care 2002 Dec;8(6):502-504 64. Bellomo R, Kellum JA, Mehta R, Palevsky PM, Ronco C. Acute Dialysis Quality Initiative II: the

Vicenza Conference. Curr Opin Crit Care 2002 Dec;8(6):505-508 65. Kellum JA, Bellomo R, Mehta R, Ronco C. Blood purification in non-renal critical illness. Blood Purif

2003;21(1):6-13 66. Mehta RL, Chertow GM. In critically ill patients with acute renal failure, outcomes, not dollars, should

drive modality choice. Crit Care Med 2003 Feb;31(2):644-646 67. Lameire N, Mehta R, Vanholder R, Sever M. The organization and interventions of the ISN Renal

Disaster Relief Task Force. Adv Ren Replace Ther 2003 Apr;10(2):93-99 68. Mehta RL. Outcomes research in acute renal failure. Semin Nephrol 2003 May;23(3):283-294 69. Mehta RL, Chertow GM. Acute renal failure definitions and classification: time for change? J Am Soc

Nephrol 2003 Aug;14(8):2178-2187 70. Chertow GM, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL.

Reasons for non-enrollment in a cohort study of ARF: The Program to Improve Care in Acute Renal Disease (PICARD) experience and implications for a clinical trials network. Am J Kidney Dis 2003 Sep;42(3):507-512

71. Pannu N, Mehta RL. Effect of mechanical ventilation on the kidney. Best Pract Res Clin Anaesthesiol

Ravindra L. Mehta

2004 Mar;18(1):189-203 72. Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, Soroko S, Freedman S,

Becker K, Spratt D, Shyr Y, Ikizler TA; PICARD Study. Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004 Apr;65(4):1357-1365

76. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; The ADQI Workgroup. Acute renal failure –

definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004 Aug;8(4):R204-212

77. Mehta RL, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler TA, Paganini EP, Chertow GM; for

the Program to Improve Care in Acute Renal Disease (PICARD). Spectrum of acute renal failure in the intensive care unit: The PICARD experience. Kidney Int 2004 Oct;66(4):1613-1621

78. Mehta RL. Acute renal failure and cardiac surgery: marching in place or moving ahead? J Am Soc

Nephrol 2005 Jan;16(1):12-14. 79. Mehta RL. Continuous renal replacement therapy in the critically ill patient.. Kidney Int 2005

Feb;67(2):781-795 80. Basi S, Pupim LB, Simmons EM, Sezer MT, Shyr Y, Freedman S, Chertow GM, Mehta RL, Paganini E,

Himmelfarb J, Ikizler TA. Insulin resistance in critically ill patients with acute renal failure. Am J Physiol Renal Physiol 2005 Aug;289(2):F259-264

81. Kellum JA, Bellomo R, Ronco C, Mehta R, Clark W, Levin NW. The 3rd International Consensus

Conference of the Acute Dialysis Quality Initiative (ADQI). Int J Artif Organs 2005 May;28(5):441-444 82. Chanchairujira T, Mehta RL. Bioimpedance and its application. Saudi J Kidney Dis Transplant

2005;16(1):6-16 83. Basi S, Pupim LB, Simmons EM, Sezer MT, Shyr Y, Freedman S, Chertow GM, Mehta RL, Paganini E,

Himmelfarb J, Ikizler TA. Insulin resistance in critically ill patients with acute renal failure. Am J Physiol Renal Physiol 2005;289(2):F259-64

84. Leblanc M, Kellum JA, Gibney RT, Lieberthal W, Tumlin J, Mehta R. Risk factors for acute renal

failure: inherent and modifiable risks. Curr Opin Crit Care. 2005 Dec;11(6):533-536. Review. 85. Kellum JA, Ronco C, Mehta R, Bellomo R. Consensus development in acute renal failure: The Acute

Dialysis Quality Initiative. Curr Opin Crit Care. 2005 Dec;11(6):527-532 86. Mehta RL. Urine IL-18 levels as a predictor of acute kidney injury in intensive care patients. Nat Clin

Pract Nephrol. 2006 May;2(5):252-253 87. Chertow GM, Soroko SH, Paganini EP, Cho KC, Himmelfarb J, Ikizler TA, Mehta RL. Mortality after

acute renal failure: models for prognostic stratification and risk adjustment. Kidney Int 2006 Sep;70(6): 1120-1126

88. Agarwal R, Chertow GM, Mehta RL. Strategies for Successful Patient Oriented Research: Why Did I (not) Get Funded? Clin J Am Soc Nephrol Mar 2006;1:340-343

89. Liu KD, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM. Timing of

Initiation of Dialysis in Critically Ill Patients with Acute Kidney Injury. Clin J Am Soc Nephrol Sep 2006;1:915-919

Ravindra L. Mehta

90. Cho KC, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, Mehta RL, Chertow GM. Survival by

Dialysis Modality in Critically Ill Patients with Acute Kidney Injury. J Am Soc Nephrol 2006 Oct 4; [Epub ahead of print]

91. Shah SH, Mehta RL. Acute Kidney Injury in Critical Care: Time for a Paradigm Shift? Curr Opin Nephrol

Hypertens 2006 Nov;15(6):561-5. 92. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A; the Acute Kidney Injury

Network.Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007 Mar 1;11(2):R31

93. Mehta RL: Comparing Dialysis Modalities for Critically Ill Patients: Are We Barking up the

Wrong Tree? Clin. J. Am. Soc. Nephrol., May 2007; 2: 413 - 414. 94. Levin A, Warnock DG, Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C; Acute Kidney Injury

Network Working Group. Improving outcomes from acute kidney injury: report of an initiative. Am J Kidney Dis. 2007 Jul;50(1):1-4.

95. Molitoris BA, Levin A, Warnock DG, Joannidis M, Mehta RL, Kellum JA, Ronco C, Shah S; on behalf of

the Acute Kidney Injury Network Improving outcomes from acute kidney injury. J Am Soc Nephrol. 2007 Jul;18(7):1992-4.

96. Molitoris BA, Levin A, Warnock DG, Joannidis M, Mehta RL, Kellum JA, Ronco C, Shah SV; on behalf of

the Acute Kidney Injury Network working group. Improving outcomes of acute kidney injury: report of an initiative. Nat Clin Pract Nephrol. 2007 Aug;3(8):439-42.

97. Mehta RL: Glycemic Control and Critical Illness: Is the Kidney Involved? J Am Soc Nephrol. 2007 Jul 26;

[Epub ahead of print]

Book Chapters

1. Chugh KS, Pal Y, Chakravarty RN, Datta BN, Mehta RL et al: Pathogenesis of renal lesions in snake bites. In Proceedings II Asian Pacific Congress of Nephrology, GJ, Becker, RC Atkins, PS Kincaid Smith (eds), Melbourne, 183-197, 1983

2. Mehta RL: New developments in continuous arteriovenous hemofiltration/dialysis. International

Yearbook of Nephrology, V. Andreucci & L. Fine (eds), Springer-Verlag, 13:271-295, 1992

3. Bellomo R, Mehta RL: Acute Renal Replacement in the ICU: Now and Tomorrow. New Horizons, Williams & Wilkins, 3(4):760-767, 1995

4. Hoyt D, Mehta RL, McKenzie R: Treatment of Acute Tubular Necrosis. Trauma, 3rd Edition. K.

Mattox, E. Moore, & D. Feliciano (eds), Appleton & Lang, 1133-1153, 1996

5. Mehta RL: Anticoagulation for Continuous Renal Replacement Therapies. Critical Care Nephrology, Kluwer Academic Publishers, 19(5)1199-1211, 1998

6. Mehta RL, Hermann D: Dialysis and Ultrafiltration, Advanced Diagnostic and Therapeutic Techniques

in the CCU, Textbook of Cardiac Intensive Care, W.B. Saunders, 7(59):735-741, 1998

7. Mehta RL: Continuous Dialysis Therapeutic Techniques. Principles & Practice of Dialysis, Williams & Wilkins, 11:141-159, 1999

8. Mehta RL: Supportive Therapies: Intermittent Hemodialysis, Continuous Renal Replacement Therapies,

Ravindra L. Mehta

and Peritoneal Dialysis. Atlas of Diseases of the Kidney, R. Schrier (ed), Current Medicine, 1999

9. Mehta RL: Acute Renal Failure. Hospital Medicine, R. Wachter, L. Goldman & H. Hollander (eds),

Williams and Wilkins, 2000

10. Mehta RL, Chertow G: Renal Replacement Therapy in the Critical Ill: Selection of Dialysis Modality. Dialysis and Transplantation: A Companion to Brenner and Rector’s The Kidney, W.B. Saunders, 2000

11. Mehta RL: Complications of Fluid Management in Continuous Renal Replacement Therapies.

Complications of Dialysis: Recognition and Management, Marcel Dekker Inc., 2000

12. Wilson WC, Mehta RL: Perioperative Anesthetic Management of the High-Risk Renal Patient. Complications of Dialysis: Recognition and Management, Marcel Dekker Inc., 2000

13. Pannu N, Mehta RL: Continuous Renal Replacement Therapies. Intensive Care in Nephrology, P.

Murray, H.R. Brady and J.B. Hall (eds), Taylor & Francis, 2003 14. Chanchairujira T, Mehta RL: Continuous Dialysis Therapeutic Techniques. Principles and Practice of

Dialysis, 3rd Edition, WL Henrich (ed), Lippincott Williams & Wilkins, 2004 15. Teehan GS, Mehta RL, Chertow GM: Dialytic Management for Acute Renal Failure. Chronic Kidney

Disease, Dialysis, and Transplantation, 2nd Edition, BJG Pereira, MH Sayegh, PG Blake (eds), Elsevier Saunders, 2005

16. Liu F, Mehta RL: Does Aggressive Intermittent Hemodialysis Measure Up to Continuous Renal

Replacement Therapy (CRRT)? Critical Care Update 2004 V Nayyar (ed), Jaypee Brothers Medical Publishers, 7:50-63, 2005

17. Mehta RL, Liu F: Acute Renal Failure. Hospital Medicine, 2nd Edition, RM Wachter, L Goldman, H

Hollander (eds), Lippincott Williams & Wilkins, 100:1007-1016, 2005 18. Liu F, Mehta RL: Renal Support in and Treatment of Acute Renal Failure. The Year in Renal Medicine,

Volume 1, J Levy (ed), Clinical Publishing, 2005

Books

Lameire NH, Mehta RL, eds: Complications of Dialysis: Recognition and Management, Marcel Dekker Inc., 2000

Invited Lectures NATIONAL 1990 1. "CAVHD: Current Status" 9th Annual Postgraduate Course, Advanced Nephrology: Nephrology for the

Consultant. La Jolla, CA January 26, 1990. 2. "Conservative Management of Renal Failure" Fifteenth Annual Postgraduate Course; Topics in Internal

Medicine, Department of Medicine. UCSD San Diego, CA, March 1, 1990. 1991 3. "Systemic Calciphylaxis" 10th Annual Postgraduate Course, Advanced Nephrology: Nephrology for the

Consultant. UCSD Continuing Medical Education Course. San Diego, CA January 31, 1991. 4. "Advances in Treatment of Acute Renal Failure" California Trauma Conference 1991, UCSD Continuing

Ravindra L. Mehta

Medical Education Course. San Diego, CA February 14-16, 1991.

5. "Lupus Nephritis" Grand Rounds - University of California, SD San Diego, CA March 15, 1991. 6. "Newer Trends in the Treatment of Hypertension" Riverside General Hospital, Riverside, CA March

13, 1991. 7. "Acute Renal Failure including Dialysis" Internal Medicine Review Course, Veterans Administration.

La Jolla, CA March 19, 1991. 8. "Renal Replacement Therapy in the ICU Setting" Grand Rounds - University of California, SD San

Diego, CA April 11, 1991. 9. "Citrate Anticoagulation: Technique and Results" American Society for Artificial Internal Organs, 37th

Annual Meeting; Session: Continuous Hemodialysis Anticoagulation. Chicago, IL April 25-27, 1991. 1992 10. "Recent Advances in Renal Therapeutics" Grand Rounds - Pomona Valley Hospital Medical Center.

Pomona, CA March 10, 1992. 11. "Continuous Hemodialysis vs Conventional Intermittent Dialysis in the Treatment of the Critically Ill

Patient with Acute Renal Failure" American Society for Artificial Internal Organs (ASAIO) 38th Annual Mtg. Nashville, TN May 7-9, 1992.

12. "Continuous Renal Replacement Therapies in Acute Renal Failure" Progress and Review in Internal

Medicine, School of Medicine UCSD. La Jolla, CA September 17, 1992. 1993 13. "Nutritional Assessment and Nutritional Support in Acute Renal Failure" 12th Annual Postgraduate

Course Advanced Nephrology: Nephrology for the Consultant. La Jolla, CA January 29, 1993. 14. "Anticoagulation Issues in Continuous Renal Replacement Therapy" American Society for Artificial

Internal Organs (ASAI0) 39th Annual Meeting. New Orleans, LA April 29 - May 1, 1993. 15. "Continuous Renal Replacement Therapy for Treatment of Acute Renal Failure" Grand Rounds -

Department of Medicine, University of California, Irvine CA June 3, 1993. 16. "Renal Replacement Options in the ICU" Short Courses in Nephrology: American Society of Nephrology

(ASN). Washington, DC November 14-17, 1993. 1994 17. "Measuring and Predicting Outcomes in Dialysis Patients" Grand Rounds - University Medical Center,

Jacksonville, Fla March 23-24, 1994. 18. "Renal Replacement Therapy in ARF" Grand Rounds - University Medical Center, Jacksonville, Fla

March 23-24, 1994. 19. "Indications, Modalities and Outcomes of Dialysis in the ICU" American Society for Artificial Internal

Organs (ASAIO) 40th Annual Mtg. San Francisco, CA April 15, 1994. 20. "Continuous Renal Replacement Therapies for Critically Ill Patients" - Roswell Park Cancer Institute.

Buffalo, NY April 23, 1994. 21. "Renal Replacement Therapies for Acute Renal Failure Matching the Method to the Patient" - American

Nephrology Nurses Association (ANNA) 25th National Symposium. Dallas, TX June 12-15, 1994 22. "Choices of Renal Replacement Therapy in the ICU" 34th Annual Scientific Symposium on Kidney

Ravindra L. Mehta

Disease. La Jolla, CA September 17, 1994.

23. "Renal Replacement Therapy in Acute Renal Failure" Loyola University Medical Center. Chicago IL

December 1, 1994 24. "Blood Volume Changes in Hemodialysis" Loyola University Medical Center. Chicago IL December 1,

1994 25. "Twenty-Four Hour Blood Pressure Control" Broadview, IL December 1, 1994. 26. "Practical Problems Associated with Slow Continuous Hemodialysis Therapy" County Medical Center.

Minneapolis, MN December 2, 1994. 1995 27. "Measuring and Predicting Outcomes in Dialysis Patients" Nephro South, ANNA. San Diego, CA

January 19, 1995. 28. "The Use of Continuous Dialytic Techniques in the ICU" California Trauma Conference. San Diego, CA

January 26-28, 1995. 29. "Intradialytic Hypotension and Changes in Body Fluid Compartments" 14th Annual Postgraduate

Course, Advanced Nephrology, Nephrology for the Consultant, University of California, San Diego CA February 4, 1995.

30. "Current Status of CRRT - Is There a Role for this Treatment for Multiple Organ Failure and Sepsis?"

Contemporary Issues in ESRD Dialysis and Transplantation. Harvard Continuing Medical Education Program. Boston, MA June 6-11, 1995.

31. "Is There a Role for Measuring Volume Changes During Hemodialysis?" Contemporary Issues in ESRD

Dialysis and Transplantation. Harvard Continuing Medical Education Program. Boston, MA June 6-11, 1995.

32. "Continuous Renal Replacement Therapy in the ICU" Tufts University. Boston, MA June 8, 1995 33. "Acute Renal Failure (dx & tx, oliguria and renal replacement therapy)" Multidisciplinary Critical Care

Review Course Society of Critical Care Medicine. La Jolla, CA August 17-20, 1995. 34. "Renal Replacement Therapy in the ICU" Current Trends in the Prevention and Treatment of ARF 14th

Annual Scientific Meeting of the National Kidney Foundation. San Diego, CA . November 3-5, 1995. 35. "Preventing Intradialytic Hypotension: Is there a role for measuring volume changes in hemodialysis?"

Council of Nephrology Nurses and Technicians 1995 Annual Meeting. San Diego, CA November 3-5, 1995.

36. "Which Outcomes Should We Measure? Experience from the San Diego Trial of CRRT vs IHD"

International Conference on Continuous Renal Replacement Therapies (CRRT). San Diego ,CA November 8-10, 1995.

37. "Anticoagulation for CRRT: What Works?" International Conference on Continuous Renal

Replacement Therapies (CRRT). San Diego, CA November 8-10, 1995. 1996 38. Presentation of data regarding future development of the Critline Technology. Althin Academy. Salt

Lake City, Utah, January 12, 1996. 39. "Predictors of Outcome in Acute Renal Failure" Advanced Nephrology, Nephrology for the Consultant.

San Diego, CA, Jan 31 - Feb 3, 1996.

Ravindra L. Mehta

40. "Highlights of the International Conference on CRRT" Advanced Nephrology, Nephrology for the

Consultant. San Diego, CA, Jan 31 - Feb 3, 1996. 41. "Acute Renal Failure in the ICU" Renal Workshop, Society of Critical Care Medicine. New Orleans,

LA February 5-9, 1996. 42. "Dose Delivery: Intermittent vs Continuous" ASAIO 42 Annual Conference Washington, DC. May 2-4,

1996. 43. “Comparisons of Continuous vs Intermittent Forms of Dialytic Therapies” Acute Renal Failure in the

21st Century. Bethesda, MD, May 6-8, 1996. 44. “Recommendations for the Management of Acute Renal Failure” NIH - Bethesda, MD. June 24, 1996. 45. “Continuous Renal Replacement Therapy in ICU Settings” 12th Comprehensive Nephrology Review

Course. Santa Monica, CA, August 2-8, 1996 46. “Indications and Outcome of Dialysis in ARF: When should dialysis be initiated? When is dialysis futile

in ARF?” NKF. New Orleans, LA, November 1-3, 1996 47. “Role of Continuous Renal Replacement Therapy” American Heart Association - 69th Scientific

Sessions. New Orleans, LA, November 10-13, 1996. 48. “Effect of Delayed Consultation on Outcomes from Acute Renal Failure” Renal Grand Rounds - Cornell

University Medical College, North Shore University Hospital, December 3, 1996. 1997 49. “Organization of a Continuous Renal Replacement Therapy (CRRT) Program” Society of Critical Care

Medicine 26th Educational & Scientific Symposium. San Diego, CA, February 6-10, 1997. 50. “Science and Methods of Continuous Renal Replacement Therapy” Society of Critical Care Medicine

26th Educational & Scientific Symposium. San Diego, CA, February 6-10, 1997. 51. “Dialysis Dose in ARF: An Overview” Second International Conference on Continuous Renal

Replacement Therapies. San Diego, CA, February 9-11, 1997. 53. “Outcomes from Acute Renal Failure: Does Renal Replacement Therapy Matter?” National Kidney

Foundation 6th Annual Spring Clinical Nephrology Meetings. Dallas, TX, Apr 17-20, 1997. 54. “CRRT: Operational Characteristics” and “CRRT: Applications” Texas Tech University Health Sciences

Center, Amarillo, TX, May 15, 1997. 55. “Clinical Trials in Acute Renal Failure: Where Do We Go from Here?” National Kidney Foundation’s

Scientific Symposium on Kidney Disease, Palm Springs, CA, Sep 20, 1997. 56. “Management of Oliguric and Non-Oliguric Acute Renal Failure” American College of Surgeons’

Clinical Congress, Chicago, IL, Oct 12-17, 1997. 57. “Initiating and Maintaining a CRRT Program”; “Fluid Management: Aspects of Volume Control”;

“Nutritional Adjustments”; “Anticoagulation in CRRT” Fellows’ Dialysis Forum: A Practical Review and Update, San Antonio, Texas, Nov 1, 1997.

1998 58. “Disaster Preparedness: Nephrological Issues” Walter Reed Army Medical Center Grand Rounds,

Washington, D.C., Apr 10, 1998. 59. “Treatment of Hypertension: Current Concepts” Pfizer Pharmaceuticals Speakers Program, Scotia, New

York, Apr 23, 1998.

Ravindra L. Mehta

60. “CRRT: Operational Characteristics”; “CRRT: Fluid and Acid Base” State-of-the-Art Management for

Acute Renal Failure in the Critically Ill Patient, Albany, New York, Apr 24, 1998. 61. “New Techniques in Dialysis for Acute Renal Failure” Southern California Transplantation Institute and

Liver Center’s Dialysis and Transplant Conference, Ontario, California, Apr 30, 1998. 62. “ARF in the SICU” UCSD Trauma Conference, San Diego, California, June 16, 1998. 63. “Continuous Renal Replacement Therapy” American Society of Nephrology Board Review Course and

Update, San Francisco, California, September 4, 1998. 64. “Management of the Patient with SIRS: Volume Therapy”; “Nutritional Management of the Critically Ill

Patient”; “Fluid and Acid Base Management in CRRT”; “Comparison of Outcomes: CRRT vs. Intermittent Hemodialysis” American Society of Nephrology Renal Week: ICU Nephrology Workshop, Philadelphia, Pennsylvania, October 23-24, 1998.

1999 65. “Recent Advances in Applications for CRRT” Baxter CRRT Meeting, Costa Mesa, CA, Jan 10, 1999. 66. “Early Referral of Patients with Kidney Disease: Does the Nephrologist Make a Difference?” UCSD

Medical Grand Rounds, San Diego, CA, Jan 20, 1999. 67. “Management of Acute Renal Failure in the ICU: Current Concepts” Cedars-Sinai Medical Center Grand

Rounds, Los Angeles, CA, Jan 21, 1999. 68. “Acute Renal Failure - Dialytic Management of ARF: Renal Replacement vs. Renal Support”; “Acute

Renal Failure - Clinical Trials in ARF: What Have We Learned?” Society of Critical Care Medicine 28th Educational & Scientific Symposium, San Francisco, CA, Jan 25, 1999.

69. “Therapeutic Interventions: Renal Replacement vs. Renal Support” Advanced Nephrology: Nephrology

for the Consultant, San Diego, CA, Feb 5, 1999. 70. “Acute Renal Failure in the ICU: Current Concepts ” Assembly in Surgery, San Diego, CA, Feb 23, 1999. 71. “Management of Acute Renal Failure in the ICU: Current Concepts” Saint Francis Medical Center,

Englewood, CA, Mar 24, 1999. 72. “CRRT in the Critically Ill Patient -Current Concepts” Renal Grand Rounds, Drew University Medical

Center, Los Angeles, CA, Apr 16, 1999. 73. “Management of Acute Renal Failure in the ICU: Is the Nephrologist Needed? ”; “Dry Weight in

Hemodialysis: Current Concepts” Nephrology Dialysis Transplantation ‘99, Monterey, CA, Apr 16-17, 1999.

74. “CRRT Hands-On Session” (workshop section); “Continuous Renal Replacement Therapy (CRRT)”

(workshop) National Kidney Foundation Clinical Nephrology Meetings, Washington, D.C., Apr 30 - May 1, 1999.

75. “Dialysis Variants: Hemofiltration, Hemodiafiltration, Continuous Methods: Hemofiltration +/- Dialysis,

Nightly/Daily Methods & Acute Dialysis” 45th Annual Conference of the American Society for Artificial Internal Organs, San Diego, CA, Jun 2, 1999.

76. CME Program Workshop on CRRT, Greenville Kidney Center, Greenville, SC, Jun 19, 1999. 77. “Continuous Renal Replacement Therapy” American Society of Nephrology Board Review Course and

Update, San Francisco, CA, Sep 3, 1999. 78. “CRRT in MODS” Critical Care Summer Session, San Diego, CA, Aug 5, 1999.

Ravindra L. Mehta

79. “When Should We Start CRRT? Renal Replacement vs. Renal Support” National Kidney Foundation of

Georgia Nephrology Update, Sea Island, GA, Oct 2, 1999. 80. “Volume Control and Blood Pressure in ESRD Patients” American Society of Nephrology Annual

Meeting, Miami, FL, Nov 8, 1999. 2000 81. “Volume Management in the ICU: Current Strategies” Advanced Nephrology: Nephrology for the

Consultant, San Diego, CA, Feb 4, 2000. 82. “Interventional Nephrology: CRRT”; “CRRT” (workshop) National Kidney Foundation Clinical

Nephrology Meetings, Atlanta, GA, Apr 14-15, 2000. 83. “Acute Renal Failure: Current Strategies for Management” Grand Rounds, Scripps Memorial Hospital,

San Diego, CA, May 9, 2000 84. “Dialysis in the ICU: Renal Replacement vs. Renal Support”; “Outcomes Predictors in Acute Renal

Failure in the ICU”; “Managing Complex Dialysis Patients in the ICU” (workshop) Renal Disease and Electrolyte Disorders Course, Aspen, CO, Jul 24-25, 2000

85. “Acute Renal Failure” Noon Conference, UCSD Medical Center, San Diego, CA, Aug 2, 2001 86 “What Have We Learned from ARF Trials: Dialytic Treatment of ARF” NIH’s Design Issues for Clinical

Trials in Acute Renal Failure, Bethesda, MD, Sep 10-12, 2000 87. “Turning Clinical Observations into Research Questions to Improve Vascular Access Outcomes”

American Society of Nephrology Postgraduate Education Courses, Toronto, Canada, Oct 11-12, 2000 88. “ICU Nephrology: Fluid-Electrolyte Emergencies”; “Renal Replacement Therapy in Acute Renal Failure”

American Society of Nephrology Annual Meeting, Toronto, Canada, Oct 13-16, 2000 2001 89. “Early Referral of the Patient with Renal Disease: Does the Nephrologist Make a Difference?” Topics and

Advances in Internal Medicine, San Diego, CA, Mar 10-15, 2001 90. “CRRT in the ICU: Renal Replacement vs. Renal Support” 3rd Annual Southern California Permanente

Medical Group Nephrology Symposium, Long Beach, CA, Mar 31, 2001 91. “Continuous Renal Replacement Therapy: Hands-On Demonstration” (workshop) National Kidney

Foundation’s Clinical Nephrology Meetings, Orlando, FL, Apr 17-22, 2001 92. “Management of Acute Renal Failure in the ICU: Current Concepts” Grand Rounds, Maine Medical

Center, Portland, ME, Jul 25, 2001 93. “ICU Nephrology” National Kidney Foundation of Southern California’s 41st Annual Scientific

Symposium on Kidney Disease, Rancho Mirage, CA, Sep 15, 2001 94. “Acute Renal Failure” Noon Conference, UCSD Medical Center, San Diego, CA, Nov 26, 2001 95 “Acute Renal Failure” Noon Conference, VA Medical Center, San Diego, CA, Nov 27, 2001 2002 96. “Acid-Base and Electrolyte Complications in CRRT” American Nephrology Nurses Association

Management and Advance Practice Meeting, San Diego, CA, Jan 12, 2002

Ravindra L. Mehta

97. “CRRT: Technique and Applications” (workshop); “Management of ARF: Case Studies” Advanced Nephrology, Nephrology for the Consultant, San Diego, CA, Feb 7-9, 2002

98. “Acute Dialysis for Inpatients and CVVHD”; “CVVHD Cases” Renal Grand Rounds, UCLA Medical

Center, Los Angeles, CA, Feb 27, 2002. 99. “Metabolic Effects of CRRT” Renal Grand Rounds, North Shore University Hospital, Great Neck, NY,

Apr 9, 2002 100. “Current Concepts and Controversies: Dialysis Dose in Acute Renal Failure” Annette Fitz Memorial

Fellowship Lecture, University of Iowa, Iowa City, IO, Jun 19, 2002 101. “Extracorporeal Therapies for Non-Renal Disease” and “Protecting the Kidney: Strategies and Results”

American Society of Nephrology Annual Meeting, Philadelphia, PA, Oct 30 – Nov 4, 2002 2003 102. “Protecting the Kidney: Strategies and Results” Advanced Nephrology: Nephrology for the Consultant,

San Diego, CA, Feb 6-8, 2003 103. “CRRT Update for the Practicing Nephrologist” and “Controversies in the Management of Acute Renal

Failure” Annual Meeting, Medical Directors of Gambro Healthcare Dialysis Clinics, Western Division, Las Vegas, NV, Apr 24-26, 2003

104. “Anemia Insights and Observations” Project Dulce, Whittier Institute, La Jolla, CA, Jul 16, 2003 105. “Continuous Renal replacement Therapy” Renal Rounds, University of Oklahoma Health Sciences

Center, Oklahoma City, OK, Sep 30, 2003 106. “An Update on Acute Renal Failure” Medicine Rounds, University of Oklahoma Health Sciences Center,

Oklahoma City, OK, Oct 1, 2003 107. “Clinical Presentation of ARF in the ICU” and “Anticoagulation in the ICU” CRRT Midwest

Symposium, Indianapolis, IN, Oct 2-3, 2003 108. “Defining and Classifying ARF: What Criteria?” American Society of Nephrology Postgraduate

Education Course, San Diego, CA, Nov 12-13, 2003 109. “Patient Stratification in ARF: The PICARD Experience” and “Prerenal Azotemia: Pathophysiology and

Management” American Society of Nephrology Annual Meeting, San Diego, CA, Nov 14-17, 2003 2004 110. “Defining and Classifying ARF: What Criteria?” Advanced Nephrology: Nephrology for the Consultant,

San Diego, CA, Jan 22-24, 2004 111. “Management of ARF in the ICU: The PICARD Experience” National Kidney Foundation 2004 Clinical

Meetings, Chicago, IL, Apr 28-May 2, 2004 112. “Emerging Concepts in Extracorporeal Support” and “Ultrafiltration in Heart Failure” Gambro Healthcare

Western Division Medical Directors Meeting, Las Vegas, NV, Jun 24, 2004

Ravindra L. Mehta

113. “Acute Renal Failure: New Approaches to Treatment” American Association of Physicians of Indian Origin 22nd Annual Convention: Translating Research Advances in Medicine to Patient Care, San Diego, CA, Jun 24-26, 2004

114. “Anticoagulation Strategies in CRRT” University of California, San Francisco Renal Grand Rounds, San

Francisco, CA, July 28, 2004 115. “Continuous Renal Replacement Therapy in the Critically Ill Patient” American Society of Nephrology

9th Annual Board Review Course & Update, San Francisco, CA, Sep 3, 2004 116. “ARF in the ICU: Lessons from the PICARD Study” American Society of Nephrology American Society

of Nephrology Annual Meeting, St. Louis, MO, Oct 29, 2004 2005 117. “What Do We Know about Human Acute Renal Failure?” UCSD Department of Medicine Grand

Rounds, San Diego, CA, Feb 2, 2005 118. “CRRT: Why, When and How?” (workshop) Advanced Nephrology: Nephrology for the Consultant, San

Diego, CA Feb 10, 2005

119. “Balancing the Heart and Kidney in Heart Failure Management” Dinner and Educational Program, Anaheim, CA, Feb 16, 2005

120. “CRRT in Sepsis: Fad or True Advance?” National Kidney Foundation’s Southwest Nephrology Conference, Litchfield Park, AZ, Feb 26, 2005

121. “CRRT”, ASN Board Review Course, San Francisco, CA, Sep 2, 2005 122. “Molecular and Inflammatory Endpoints in ARF Trials” American Society of Nephrology Annual

Meeting, Philadelphia, PA, Nov 10-13, 2005 2006 123. “Acute Kidney Injury and Critical Illness: Cause or Consequence?” (Grand Rounds) and “Molecular and

Inflammatory Endpoints in ARF Trials” (Research Seminar) Loyola University Medical Center, Chicago, IL, Mar 14, 2006

124. “The Acute Kidney Injury Network” National Kidney Foundation Spring Clinical Meetings, Chicago, IL,

Apr 19-23, 2006 125. “CRRT in the Critically Ill Patient” Nephrology Grand Rounds, Harbor-UCLA Medical Center, Torrance,

CA, Aug 14, 2006 126. “Initiation of CRRT” CRRT Midwest Symposium, Indianapolis, IN, Sep 28, 2006 INTERNATIONAL 1991 1. "Continuous Renal Replacement in the ICU: Current Concepts and Choice of Modality" Sociedade

Brasileira de Nefrologia Regional. Rio de Janeiro, Brazil Aug 14-22, 1991.

Ravindra L. Mehta

2. "Continuous Renal Replacement in the ICU: Clinical Use and Practical Considerations" Sociedade

Brasileira de Nefrologia Regional. Rio de Janeiro, Brazil Aug 14-22, 1991 1992 3. “Continuous Renal Replacement and Choice of Modality” University of Alberta Hospital,

Edmonton, Alberta, Canada, May 31 - Jun 2, 1992. 4. “Continuous Renal Replacement in ICU - Clinical Uses and Practical Considerations”

University of Alberta Hospital, Edmonton, Alberta, Canada, May 31 - Jun 2, 1992. 5. “Continuous Hemodialfiltration in ICU: Modalities of Continuous Hemodialfiltration” 6th

European Congress on Intensive Care Medicine. Barcelona, Spain, Oct 27-31, 1992. 1994 6. "Anti-Coagulation for Continuous Renal Replacement Therapies" Grand Rounds - Toronto General

Hospital, Toronto, Ontario, Canada, Mar 26, 1994. 7. "Renal Replacement Options in the Intensive Care" Continuing Medical Education Silver Jubilee

Conference of the Indian Society of Nephrology. Chandigarh, India, Oct 3, 1994. 1995 8. "New Developments in Continuous Renal Replacement Therapy." Developments in Nephrology.

Noordwijkerhout, The Netherlands, May 22-23, 1995. 1996 9. “New Techniques to Control Uremia and Hyperkalemia in the Disaster Setting” Renal Aspects of

Disaster Relief. Macedonia, May 24-26, 1996. 10. “Is there a role for measuring volume changes during hemodialysis?” and “Impact of renal replacement

therapy on outcomes from ARF in the ICU”. The Montreal General Hospital, Quebec Canada, Jun 5-7, 1996.

11. “Anticoagulation Strategies” Continuous Hemofiltration Therapies Symposium, Paris, France, Dec 5-6,

1996. 1997 12. “Acute Renal Failure” International Symposium on Intensive Care and Emergency Medicine, Brussels,

Belgium, Mar 18-21, 1997. 13. “Replacement Therapies: Continuous vs. Intermittent Therapies” International Symposium on Intensive

Care and Emergency Medicine, Brussels, Belgium, Mar 18-21, 1997. 14. “Continuous Dialysis Therapy in the ICU” XIVth International Congress of Nephrology. Sydney,

Australia, May 25-29, 1997. 15. “US vs. Haiti ” ARF Satellite Symposium Cairns, Australia, Jun 1-3, 1997. 16. “Pathophysiology of Multiple Organ Failure in I.C.U.”; “What is CRRT?”; “Selection of Patients for

CRRT”; “The Management of Multiple Organ Failure: An Overview” Liaquat National Hospital Symposium, Karachi, Pakistan, Dec 1-2, 1997.

17. “Place of Hemofiltration in 1998" Continuous Hemofiltration Therapies in the ICU, Paris, France, Dec 4-

5, 1997. 18. “Which Dialysis Therapy for Acute Renal Failure?” Berliner Dialyseseminar, Berlin, Germany, Dec 5-6,

Ravindra L. Mehta

1997.

1998 19. “Clinical Trials in ARF: What Have We Learnt?”; “When Should We Start CRRT? Renal Replacement

vs. Renal Support”; “CRRT as a Fluid Regulatory Device” International Conference on CRRT, San Diego, CA, Mar 5-7, 1998.

20. “Antithrombotic Therapy during CRRT” First International Course on Critical Care Nephrology,

Vicenza, Italy, May 20-23, 1998. 21. “Principles and Methods of Anticoagulation in CRRT” Continuous Renal Replacement Therapy and

Anticoagulation for the Treatment of Critical States Symposium, Moscow, Russia, Oct 6, 1998. 22. “Fluid Management in CRRT”; “Principles and Methods of Anticoagulation in CRRT”; “Outcomes with

CRRT: Which One Should We Measure?”; “Who’s Going to Dialyze: The Intensivist or the Nephrologist?” 3rd National PRONEP Meeting on Nutrition Therapy and Pharmacotherapy, Rio de Janeiro, Brazil, November 5, 1998.

1999 23. “Fluid Management” (workshop); “Protocol-Driven Fluid Regulation”; “Respiratory Failure”;

“Withholding and Withdrawing Support” Fourth International Conference on CRRT, San Diego, CA, Mar 11-13, 1999.

24. Case Discussions, International Society of Nephrology Congress, Buenos Aires, Argentina, May 3, 1999. 25. “Severity of Illness Scoring in ARF: Where do we Stand?”; “Initiating Dialysis for ARF: Renal

Replacement vs. Renal Support”; “Advances in Continuous Renal Replacement Therapy” International Society of Nephrology Satellite Symposium on Acute Renal Failure, Santiago, Chile, May 7-8, 1999.

26. “Anticoagulation: Achilles Heel of CRRT?” Fourth International Conference on Continuous

Hemofiltration, Darmstadt, Germany, May 14, 1999. 27. “Past, present and future of CRRT” Annual Meeting of the International Society of Blood Purification,

Prague, Czech Republic Oct 8, 1999 2000 28. “Fluid Management” (workshop); “Citrate Anticoagulation: 10 Year Experience” Fifth International

Conference on CRRT, San Diego, CA, Mar 2-4, 2000. 29. ”Severity of Illness Scoring for ARF: Techniques and Results”; “Citrate Anticoagulation: Technique,

Advantages, Risk, Implementation”; “Dialysis in the ICU: An Approach for a New Millennium” 5th Annual Uldall Visiting Professor, University of Toronto, Toronto, Ontario, Canada, May 24-26, 2000

30. “Epidemiology and Prognosis of Acute Renal Failure in the Intensive Care Unit”; “Renal Replacement

Therapy in Acute Renal Failure”; “Extracorporeal Therapy in Extra-Renal Diseases”; “Dry Weight Evaluation in Chronic Dialysis” 20th Brazilian Society of Nephrology Meeting, Natal, Brazil, Sep 24-27, 2000.

31. “Continuous Renal Replacement Therapy” 31st Annual Conference of Indian Society of Nephrology,

Mumbai, India, Nov 24-26 32. “Continuous Renal Replacement Therapy” Nephrology Update 2000, Colombo, Sri Lanka, Nov 28, 2000 2001 33. “Indications for Dialytic Intervention in the ICU: Renal Replacement and Support” International

Conference on Dialysis III, Miami Beach, FL, Jan 17-19, 2001

Ravindra L. Mehta

34. “Continuous Renal Replacement Therapies – Indications for Continuous & Intermittent Renal

Replacement Therapy” Society of Critical Care Medicine’s 30th International Critical Care Congress, San Francisco, CA, Feb 9-10, 2001

35. “ADQI: Results for CRRT”; “Fluid Management: Principles of Management with Different CRRT

Equipment” (workshop); “Acid Base and Electrolyte Balance”; “CRRT Support” 6th International Conference on Continuous Renal Replacement Therapies, San Diego, CA, Mar 8-10, 2001

36. “Fluid Management in CRRT”; “Liver Support Systems” Second International Course on critical Care

Nephrology, Vicenza, Italy, May 22-25, 2001 37. “ICU Nephrology: Continuous Therapies”; “Dialytic Support for ARF” American Society of

Nephrology/International Society of Nephrology World Congress of Nephrology, Oct 10-17, 2001 2002 38. “High vs. Low Volume Continuous Renal Replacement Therapies” Society of Critical Care Medicine’s

31st International Critical Care Congress, San Diego, CA, Jan 26-30, 2002 39. ”Citrate Anticoagulation for CRRT: Which Method?” (workshop); “Fluid Management” (workshop);

“Protecting the Kidney”; “Does the Dose of Dialysis Affect Outcomes?”; “Emerging Technologies in Extracorporeal Support” Seventh International Conference on Renal Replacement Therapy, San Diego, CA, Mar 14-16, 2002

40. “Critical Care Nephrology: A New Discipline”; “Non-Renal Indications for CRRT” X Brazilian Congress

on Critical Care Therapy, Rio de Janeiro, Brazil, Apr 26-30, 2002 2003 41. “Summary of ADQI Consensus Findings” Advances in ESRD 2003 International Conference on Dialysis

V, Miami, FL, Jan 29-31, 2003. 42. “Fluid Regulation: The Role of Dialysis”, “Lessons from the PICARD Trial”, “Fluid Management”

(workshop), and “Citrate Anticoagulation for CRRT: An Update” (workshop) Eighth International Conference on Renal Replacement Therapies, San Diego, CA, Mar 6-8 , 2003

43. “Continuous Renal Replacement Therapy in the Critically Ill Patient” World Congress of Nephrology,

Berlin, Germany, June 8-12, 2003 44. “Can We Change the Course of Acute Renal Failure?” World Congress of Nephrology Satellite

Symposium on ARF, Ghent, Belgium, Jun 13-15, 2003 45. “Rationale for CRRT in ARF” and “Renal Function Preservation: Role of Diuretics” Extra-Renal

Therapies in Intensive Care Symposium, Marne-la-Valle, France, Dec 4-5, 2003 46. “Acute Renal Failure – Current Developments” Berliner Dialyseseminar, Berlin, Germany, Dec 5-6, 2003 2004 47. “Renal Failure in the Critically Ill: Outcome and Risk Predictors”, “Anticoagulation for CRRT: Making it

Effective and Safe”, “Hemodynamic Monitoring and Considerations in Dialysis Therapies in the ICU”, “Recent Advances in the Management of Acute Renal Failure” NephroAsia 2004, Singapore, Feb 9-12, 2004

48. “Renal Function Preservation: The Role of Diuretics” and “Fluid Management” (workshop) Ninth

International Conference on Renal Replacement Therapies, San Diego, CA, Feb 26-28 , 2004

Ravindra L. Mehta

49. “The Acute Dialysis Quality Initiative”, “Fluid Management in CRRT”, and “Liver Support Systems”

Third International Course on Critical Care Nephrology, Vicenza, Italy, Jun 2-5, 2004 50. “Can We Change the Course of Acute Renal Failure?”, “Pathophysiology of Acute Renal Failure:

Emerging Concepts”, “Collaborative Networks in Acute Renal Failure” 9th Peruvian Congress of Nephrology, Lima, Peru, Oct 14-17, 2004

2005 51. “Timing is Everything: The Case for Early Intervention”, “A Systems-Based Approach to CRRT”

(workshop) and “Fluid Management” (workshop) 10th International Conference on Renal Replacement Therapies, San Diego, CA, Feb 26-28, 2005

52. “Advances in Technology”, “Fluid Management”, “A Systems-Based Approach to CRRT” (workshops)

and “Timing is Everything: The Case for Early Intervention” International Conference on Continuous Renal Replacement Therapies, San Diego, CA Mar 10-12, 2005

53. “Fluid Management” (workshop), “What do We Know about Human ARF?”, and “When Should We

Start Dialysis?” World Congress of Nephrology Satellite Symposium on Acute Renal Failure, Malaysia, Jul 1-3, 2005

54. “Acute Kidney Injury: Cause or Consequence of Critical Illness?” Academic Session to celebrate the

retirement of Dr. Norbert Lameire, Gent, Belgium, Oct 1, 2005 55. “Fluid Management in CRRT” and “Anticoagulation during CRRT” Forefronts in Continuous Blood

Purification-Nanjing Forum 2005, Nanjing, China, Oct 8-12, 2005 56. “ARF Definition: Any Consensus?”, “What is the future in RRT?” and “Fluid Management” Extra-Renal

Therapies in Intensive Care Congress, Nice, France, Nov 24-25, 2005 57. “Overview of Treatment of ARF in the ICU” and “Acute Kidney Injury and Critical Illness: Cause or

Consequence?” Annual Conference of the Indian Society of Nephrology, Cochin, India, Dec 1-3, 2005 2006 58. “Advances in Technology”, “Fluid Management”, “A Systems-Based Approach to CRRT” (workshops)

and “Terminology, Definitions, Classification and Grading: The AKIN Project”, International Conference on Continuous Renal Replacement Therapies, San Diego, CA Mar 2-4, 2006

59. “Clinical and Biological Markers in AKI”, “When Should Dialysis be Initiated in the ICU?” and “New

Concepts and Classification of AKI” Uruguayan Congress of Nephrology, Montevideo, Uruguay, May 4-6, 2006

60. “Acute Kidney Injury and Critical Illness: Cause or Consequence?” European Renal Association-

European Dialysis and Transplant Association Congress, Glasgow, Scotland, July 15-18, 2006 Research Grants

Dates Title Role Agency Direct Costs

01Jul84 30Jun86

Monocyte Receptors for Complement in Systemic Lupus Erythematosus P.I. National Kidney

Foundation $34,000

01Jul84 30Jun86

Monocyte Receptors for Complement in Systemic Lupus Erythematosus P.I.

National Kidney Foundation Upstate New York

$8,480

Ravindra L. Mehta

01Jul84 30Jun86

Function of Complement Receptors on Mononuclear Phagocytes P.I. Genesee Valley

Heart Association $18,000

01Jul86 30Jun87

Function of Complement Receptors on Mononuclear Phagocytes P.I.

National Kidney Foundation (NKF) Upstate New York

$3,500

01Aug86 31Jul91

Function of C3b and C3bi Receptors on U937 Cells P.I.

NIH First Investigator Award

$321,490

01Jul87 30Jun88

Function of C3b and C3bi Receptors on U937 Cells AHA Grant in Aid $24,000

01Oct87 30Sep88

Efficacy and Relative Cost of Continuous Arterio-Venous Hemofiltration Compared to Hemodialysis in the Treatment of Acute Renal Failure

P.I. Strong Memorial Hospital $27,433

01Aug88 30Jul89

Efficacy and Relative Cost of Continuous Arterio-Venous Hemofiltration Compared to Hemodialysis in the Treatment of Acute Renal Failure

P.I. HOSPAL Medical Corporation $5,000

30Sep90 29Sep95

CAHVD vs. Hemodialysis Treatment in Acute Renal Failure P.I.

Agency for Health Care Policy Research (AHCPR)

$1,625,847

01Jan93 30Jun95

Auriculin hANP (human Artrial Natriuretic Peptide) in the treatment of Acute Tubular Necrosis (ATN) Multi-center trial

P.I. SCIOS, Nova Inc. N/A

01Jul95 30Jun96

Clinical Efficacy and Safety Study of Diaspirin Cross-Linked Hemoglobin (DCLHb) Solution in Patients with Chronic Renal Failure Undergoing Hemodialysis, HL 16887

P.I. Harris Labs N/A

01Sep95 31Aug97

In Line Hematocrit Monitoring for Volume Determination in Chronic Hemodialysis Patients

P.I. In-Line Diagnostics N/A

01Feb96 31Dec97

Intravenous Auriculin Anaritide in the treatment of Acute Tubular Necrosis (ATN) P.I.

SCIOS

N/A

01Jun96 30Jun97

Clinical Evaluation of Thoracic Electrical Bioimpedance Analytic Determination of Cardiac Output in patients treated with Dialysis

P.I. Cardio-Dynamics N/A

01Sep95 31Aug97

In Line Hematocrit Monitoring for Volume Determination in Chronic Hemodialysis Patients

P.I. In-Line Diagnostics N/A

01Dec97 31Aug03

Predicting and Improving Outcomes in Acute Renal Failure P.I. NIH-NIDDK $437,212/yr

Ravindra L. Mehta

15Mar98 14Mar00

On-Line Production of Ultrapure Water for Hemodialysis P.I.

NIH-SBIR Subcontract to Clarigen, Inc.

$61,526

30Jun01 31May02

Planning Grant for Masters Degree Program in Clinical Research P.I. UC Office of the

President $25,000

01Feb02 30Jun04

Assessment of the Effect of Vascular Blood Flow Rate and Fiber Bundle Volume on Dialyzer Clotting by Ultrasound

P.I. NIH-SBIR Subcontract to Transonic Systems

$44,000

01Apr03 31Dec05

Continuous Renal Replacement Therapy Dose Feasibility Study P.I. Baxter Healthcare

Corporation $134,709

01Jul03 30Jun05

PICARD-Nephros Renal Assist Device (RAD) Project P.I. Nephros

Therapeutics $152,846

01Sep03 31Aug07

FREEDOM-Frequent Dialysis Outcomes and Markers P.I. NIH Subcontract to

UCSF $66,347/yr

01Sep03 31Jul04

Renal Biopsy in Acute Renal Failure – Concept Development Project Co-P.I. NIH-NIDDK $50,000

01Sep04 31Aug05

Designing a Multicenter Registry for Acute Kidney Injury – Concept Development Project

Co-P.I. NIH-NIDDK $50,000

01Dec04 30Nov09 General Clinical Research Center Asst.

Director NIH $3,014,571/yr

15Sep05 31Aug10

Science Education Partnership Award (SEPA) Co-P.I. NIH-NCRR $1,286,258

30Sep05 30Jun10

Clinical Research Enhancement through Supplemental Training

Program Director NIH $350,000/yr

01Jul06 30Jun08

Protein C Levels in Patients with Acute Kidney Injury P.I. Eli Lilly & Co. $352,500