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c. 2007 Bauman College
NE 104.1
Micronutrients:Calcium & Magnesium
c. 2007 Bauman College
Macronutrient Review
• Carbohydrates
• Protein
• Fat
• Water
• Fiber
c. 2007 Bauman College
What are Micronutrients?
• Vitamins, minerals, trace minerals, phytonutrients
• Major (macro) Minerals (mg or gm)
– Ca, Mg, Na, K, Cl, P, S
• Minor (micro) Minerals (mcg or mg)
– Fe, Cu, Zn, Se, Cr, Mn, Si, Va, Bo, Molybdenum
• Heavy Metals
– Al, As, Cd, Hg, Pb
c. 2007 Bauman College
Where do micronutrients come from?
c. 2007 Bauman College
Function of Micronutrients
• Needed to metabolize macronutrients• Function as cofactors for all chemical
reactions• Support enzyme activity• Needed for hormone binding and
activation• Regulate pH, metabolism, cholesterol
and blood sugar• Act as biological response modifiers
c. 2007 Bauman College
Micronutrients and Biochemical Individuality
• Dr. Roger Williams developed concept of biochemical individuality in the 1960s
• Experimented by breeding guinea pigs to get genetically similar animals
• Found that despite given same amounts of nutrients, they all showed widely differing levels in blood. Eg., some needed 10 mg. Vit. C to achieve Level X in blood, while others needed 2 grams (2000 mgs!)
• Found same variability when he applied what he learned to humans.
c. 2007 Bauman College
Q: Which nutrients do you need when?
A: Your body needs everything all the time!
needs link.html
c. 2007 Bauman College
Got minerals?
c. 2007 Bauman College
Role of Minerals in the Body
• Cofactors to enzymatic reactions• Structural Support: Connective Tissue,
Vascular Stability• Anti-oxidants• Anti-inflammatory• Cancer Protectant• Hormone Regulators• Acid Buffers (pH homeostasis)
c. 2007 Bauman College
Mineral Deficiency is Epidemic
• What are the Causes?– Soil depletion– Refined foods– Age– Stress
• “Unfortunately, modern man cannot live by food alone….Commercial agriculture is depleting the soil and destroying the ability of plants to utilize minerals”
-Bernard Jensen and Mark Anderson
c. 2007 Bauman College
What about Balance?
• Balance is as important as availability and assimilation
• Minerals compete for absorption, eg.,
– Zinc and copper
– Calcium and magnesium
– Sodium and potassium
• Excess calcium can also reduce absorption of zinc, phosphorous and manganese.
• Excess iron can inhibit absorption of calcium
And so on….
c. 2007 Bauman College
Calcium: The Knitter
• Most abundant mineral in the body– 99% of calcium in the body is in the bone– Calcium is mostly outside the cell (extracellular)
• Functions– Building & maintaining bones & teeth– Muscle contraction – Heartbeat regulation– Blood clotting– Hormone production– Nervous system support– Mediates constriction and relaxation of blood
vessels
c. 2007 Bauman College
Calcium Absorption & Metabolism
• Calcium Enhancers & Cofactors– HCL, Some Protein, Some Fat– Magnesium, Boron– Vitamin D, Vitamin K, Vitamin A, Vitamin C
• Calcium Inhibitors– Excess Phosphorus, Mg, Zn– Excess fiber: phytates, oxalates, tannins– Antacids
c. 2007 Bauman College
Hormonal Regulation of Calcium
• Parathyroid Hormone (parathormone)• Vitamin D/calcitriol• Calcitonin• Estrogen• Progesterone
c. 2007 Bauman College
Calcium Depleters
• Soda
• Caffeine
• Alcohol
• Nicotine
• Sugar
• Excess Na, P, Fl, Al
• Stress
c. 2007 Bauman College
Calcium Sources
• Dairy (raw is better, some fat is better)• Green leafy veggies (kale, collards, nuts,
seeds, esp sesame seeds)• Sea veggies (kelp, wakame, hijiki, dulse)• Bone stock• Sardines with bones• Oysters• Mineral broth• Sesame
c. 2007 Bauman College
Calcium Deficiency
• Symptoms– Insomnia, irritability, heart palpitations– Leg cramps, jumpy legs, numbness,
tingling– Uncontrolled muscle contraction (“calcium
tetany”)– Osteomalacia (aka rickets)– Osteopenia– Osteoporosis
c. 2007 Bauman College
Calcium Excess
• Is readily excreted
• But, If too much Ca intake (or taken w/o co factors:
– Interferes with absorption of other minerals esp Mg
– Kidney stones
– Constipation
– Soft tissue calcification
– Calcification of heart vessels
– Excess muscle contraction (“calcium rigor”)
c. 2007 Bauman College
Calcium RDA
• (Only 25-40% of oral Ca is absorbed, we lose about 340 mg/day)
• Infants: 400-600mg• Children: 800mg• Adolescents: 1200mg• Adult Men: 800mg• Adult Women: 1200mg• UL: 2500 mg • Ratio
– 1.5 Ca: 1 Mg (600mg Ca:400mg Mg)– 1:1 (Menopause)
c. 2007 Bauman College
Calcium Supplementation
• General: 800-1200mg• Women: 500-600 mg Ca, 300-400 mg Mg• Menopause: 1:1or 1:2 (Ca:Mg)• Forms
– Calcium citrate, Calcium glycinate (“ate” forms)
– Calcium Hydroxyapatite• (MCHC: Micro Crystalline
Hydroxyapatite Complex) – Avoid: Ca carbonate, Ca oxide, TUMS
c. 2007 Bauman College
Calcium & Weight Loss
• 1000 mg of additional calcium intake results in a 17.6 lb difference in body weight(J. Clin Endocrinol Metab. 2000, Dec; 85 (12): 4635-8)
• Girls who consume more calcium tend to weigh less and have lower body fat than those with low fat consumption, although it is not important whether the calcium comes from food or supplements(Experimental Biology Meeting, Oct 2003)
c. 2007 Bauman College
Magnesium: The Relaxer
• Involved in nearly every body process• Involved in over 300 enzyme systems• Is mainly inside the cells (intracellular) –
works with ATP to produce energy• Considered the “Relaxation Mineral”• Concentrated in metabolically active areas:
heart, muscles• In balance with Calcium
c. 2007 Bauman College
Functions of Magnesium
• Activates protein & carbohydrate metabolism
• Required for Ca to be utilized• Activates enzymes for energy production• Activates enzymes for glucose to glycogen
conversion• Critical cell membrane component
– Facilitates nutrients getting in,
wastes getting out
• Natural “calcium channel blocker”
c. 2007 Bauman College
Magnesium Sources
• Think green! Mg is the Fe of the plant world
• Wheat germ, bran, whole grains, nuts, seeds
• Beans, legumes
• Avocado
• Dried apricot
• Hard (mineral) water
c. 2007 Bauman College
Magnesium Depleters/Inhibitors
• Too high calcium• Too low calcium• Stress (mental + cold, trauma, surgery)• Alcohol, sugar, caffeine, SAD• Excess phosphorus• Antibiotics, diuretics, birth control• Age• Oxylates and phytic acid• Excessive D2 (ergocalciferol, artificial D2 found
in milk, nut milks, soy milk)
c. 2007 Bauman College
Magnesium Cofactors
• Calcium
• Vitamin B6 (25-50 mg)
• Na, K, Phosphorus
• Vitamins C, E, Bs
c. 2007 Bauman College
Magnesium Deficiency
• Muscle cramps
• PMS
• Fatigue
• Irritability
• Insomnia
• Constipation
• Heart arrhythmias
• SAD
• Elderly
• Anorexic
• PMS alcoholics
• Drugs
• Asthma
• Migraine
c. 2007 Bauman College
Magnesium RDA
• Infants 40-60mg
• Children (age 1-10) 80-170mg
• Teens (age 11-14) 270-280mg
• Females (age 15-18) 300mg
• Pregnant women 300mg
• Males (age 15-18) 350mg
• Females (age 19 up) 400mg
c. 2007 Bauman College
Magnesium Supplementation
• Chelated forms (“ate”) best, 200 mg dosetake with Vit B6, 25-50 mg– citrate, taurate, glycinate, succinate, malate
• Mg Citrate alone may act as a laxative• Mg oxide: not well absorbed• Epsom salts (MgSO4) in a bath allows Mg to
soak thru the skin• Multi: 300-500 mg• Mg supplementation is CI with kidney disease
c. 2007 Bauman College
Top Five•What are your top five takeaways from discussion of calcium and magnesium?•List five food sources of calcium showing how much is available in a 100 (3.5 oz.) serving•List five food sources of magnesium, showing how much is available in a 100g (3.5 oz.) serving
c. 2007 Bauman College
Food for Thought
1. 1. How does the body keep blood calcium constant regardless of intake?
2. Discuss four client issues where you would suspect a magnesium deficiency. What foods would you recommend to rectify it?
3. Describe why the SAD, specifically white flour and sodas, are so deleterious to
bone health.