STEROIDSBy: Mark Avery

Anabolic Steroids

Street Names: Arnolds Gym Candy Roids Pumpers Stackers Gear Juice

Anabolic Steroids

Oral Anabolic Steroids: 17-alpha methyl testosterone (Android) 17-alpha ethyl testosterone (Maxibolin) 1-methyl testosterone (Primobolan) Androstenediol (“Andro” Food Supplements) Androstenedione Dehydroepiandrosterone (DHEA)

Anabolic Steroids

Injectable Anabolic Steroids: 19 nortesterone ester derivatives (Durabolin) Testosterone ester derivatives (Oreton) Testosterone cypionate derivatives (Virilon) Boldenone Stanozolol (Winstrol) oral form as well.

How They Work

Steroid is consumed either orally or via injection.

Travels to the androgen receptors on various cells.

This connection activates the hormone receptor creating a messenger RNA.

How They Work

Signals DNA to construct specific proteins.

Proteins travel throughout the body starting the anabolic growth responses.

History

1931- Male hormone androstenone isolated.

1934- Androstenone synthesized. 1935- testosterone identified and

synthesized. 1937- Clinical trials on humans with

testosterone began.

History

During WWII, German scientist synthesized other anabolic steroids and tested them on inmates at concentration camps.

German Soldiers- increase aggression 1958- Dianabol approved in U.S by the

FDA. 1972- no difference in study between

patients with PEDS and placebo. 2001- Clear increase in muscle mass and

decrease in fat associated with high doses of AS.

Medical Use

Bone Marrow Stimulation- aplastic anemia

Growth Stimulation- use GH now Appetite Stimulate- AIDS, Cancer Induction of male puberty- extreme delay Reversable male contraceptive – future Hormone replacement therapy (men) Gender dysmorphia – psyciatric

More Medical Uses

Gain weight after severe illness, injury, or infection.

Certain types of anemia Breast cancer in some women.

Schedule Rating of Drug

Anabolic steroids are Schedule III.

Physiological Effects

Increased muscle mass and strength Growth of facial and body hair Deepening of voice

Psychological Effects: Increased Aggression “Roid Rage”

Side Effects

Acne Shrunken Testicles Gynecomastia High Blood Pressure High Cholesterol Liver Malfunction Enlarged Prostate Balding

Sources:

http://www.steroidabuse.com/how-anabolic-steroids-work.html

http://www.steroid.com http://www.nlm.nih.gov/medlineplus/

anabolicsteroids.html http://teens.drugabuse.gov/facts/

facts_ster1.php http://www.mayoclinic.com/health/drug-

information/DR602077