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The diagnosis of pregnancy requires a
3multifaceted approach using 3 main diagnostic
tools, history and physical examination,
hormonal assays, and ultrasound (US).
Currently, physicians may utilize all of these
tools to diagnose pregnancy at early gestation
and to help rule out other pathologies
• Presumptive (subjective )signs
•Objective (probable) signs
Diagnostic (positive/sure) signs of pregnancy
These signs are least indicative of
pregnancy; they could easily indicate
other conditions. signs lead a woman to
believe that she is pregnant
(1)Amenorrhea:It is the earliest symptoms of pregnancy. In
healthy women whose menstrual cycles are
regular, missing one or more menstrual
periods leads to consideration of pregnancy.
D.D( others )?
Are experienced by almost half of all pregnant women during the first three months of pregnancy and result from elevated HCG level .The symptoms frequently occur in the early part of the day, and disappear within few hours and commonly called Morning Sickness. These symptoms disappear spontaneously from 6 to 12 wks
(2) Nausea and Vomiting
3)Excessive fatigue:
May be noted within a few weeks after the
first missed menstrual period and may be
persisted throughout the first trimester.
• Is caused by pressure of the expanding uterus on the bladder.
• It subsides as pregnancy progresses and the uterus rises out of the pelvic cavity.
• The uterus returns during the last weeks of pregnancy as the head of the fetus presses against the bladder.
4)Engorgement of the breasts
due to the hormone-induced growth of the
secretary ductal system results in subjective
symptoms of tenderness and tingling,
especially of the nipple area.
Montgomery's tubercles: from 12-30
nodules appear on primary areola, opening
of sebaceous glands and keeps the nipple
soft.
Secondary areola: appears from 16
weeks, covering half of breast, persist
year after delivery.
More prominent and visible veins due to
the increased blood supply.
5) Quickening:
It is the first perceptible fetal movement felt
by the pregnant mother, occurs about 18-20
wks after the last menstrual period in a
primigravida, but may occur as early as 16
wks. in a multigravida. Quickening is the
fluttering sensation in the abdomen that
gradually increases in intensity and frequency.
II-Objective (probable) signs:
An examiner can perceive the objective
changes that occur in pregnancy. They are
more diagnostic than the subjective
symptoms; however, their presence does not
offer a definite diagnosis of pregnancy.
Changes in the pelvic organs:
These changes caused by increased vascularity
and congestion during the first three months of
pregnancy.
1- Hegar's sign:
It is the softening of the isthmus of the
uterus, the area between the cervix and
body of the uterus, which occur at 6 to 8
weeks of pregnancy. This area may become
so soft that on bimanual examination the
anterior fornix fingers and abdominally
fingers meet each other.
2- Chadwick's sign:
Is the deep red to purple or bluish
coloration of the mucous membranes of
the cervix, vagina and vulva due to
vasocongestion of the pelvic vessels.
McDonald's sign :
It is an ease in flexing the body of the
uterus against the cervix.
Osiander's sign:
It is increase pulsation in lateral fornix
due to increase vascularity resulted in
pelvic congestion.
Enlargement of the abdomen:
During the childbearing years is usually
regarded as evidence of pregnancy,
especially if the enlargement is progressive
and is accompanied by a continuing
amenorrhea.
Braxton Hicks contractions:
Are ordinary painless that occur at
irregular intervals throughout pregnancy
but are felt with abdominal palpation after
28 weeks. As the pregnancy progresses
these contractions become uncomfortable
and are often called" false labor ".
Uterine Soufflé:
May be heard when auscultating the
abdomen over the uterus. It is a soft
blowing sound at the same rate as the
maternal pulse and is due to the
increased uterine vascularization and the
pulsation through the placenta.
Uterine soufflé is sometimes confused
with the funic soufflé which is a soft
blowing sound of blood pulsating through
the umbilical arteries. The funic soufflé is
as the same rate as the fetal heart rate
Skin changes: Changes as pigmentation of the skin and the
appearance of abdominal stria gravidarium are
common manifestation in pregnancy. Facial
cholasma occurs in varying degrees after 16
weeks. Also linea nigra also appear in the
abdomen. The pigmentation of the nipple and
areola may darken, especially in primigravidas.
- Fingernails. Some patients note marked thinning and
softening by the sixth week.
Ballottement:
Is a passive fetal movement elicited by
pushing up against the cervix with two
fingers. This pushes the fetal body up and
down as it falls back, the examiner feels a
rebound.
Pregnancy test: Are based on analysis of maternal blood or
urine for the detection of human chorionic
gonadotrophins(hcG).
Pregnancy tests: All depend on the
detection of hCG either in urine or in serum. HCG levels peak between 50 to 90 days
after the last menstrual period.
Production of hCG begins as early as the day of implantation
(a) Urine. This test can be performed accurately 42
days after the last menstrual period or 2 weeks after the
first missed period. The first urine specimen of the
morning is the best one to use.
(b). Blood. Radioimmunoassays (RIA) can detect HCG
in the blood 2 days after implantation or 5 days before
the first menstrual period is missed.
III -Diagnostic (positive/sure) signs of
pregnancy
The positive signs of pregnancy are
completely objective, cannot be confused
with pathological states, and offer conclusive
proof of pregnancy, but they are usually not
present until after the fourth month of
pregnancy.
1-The fetal heart beats:
The fetal heart begins beating by the 24th day
following conception. It is audible with a doppler by
10 weeks of pregnancy and with a fetoscope after the
16th week . It is not to be confused with uterine
souffle or swishlike tone from pulsating uterine
arteries. The normal fetal heart rate is 120 to 160
beats.
2-Fetal movements:
Are actively palpable by a trained
examiner after about 20weeks of
gestation. They vary form a faint flutter in
the early months to more vigorous
movements late in pregnancy.
3-Ultra sound:
Is a technique that can be used for a
positive diagnosis as early as the fourth to
fifth week of pregnancy.
The earliest structure identified is the
gestational sac (GS). The GS can be seen on
TVUS by 4-5 weeks' gestation and grows at
a rate of 1 mm/d in early gestation
4-Fetal Parts:
Can be palpated through the abdominal wall
5-Radiological (x-ray):
An x-ray will identify the entire fetal skeleton
by the 12th week. In utero, the fetus receives
total body radiation that may lead to genetic
or gonadal alterations. An x-ray is not a
recommended test for identifying pregnancy.