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Embryo Implantation. By: A.Abdeyazdan With best regards to: Dr.M.Mokhtari. What is Embryo Implantation ?. Preimplantation. Uterus ( implantation window) Thickness of endometrial wall growth of secretory glands 7 days after ovulation - PowerPoint PPT Presentation
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IN THE NAME OF GOD
By: A.AbdeyazdanWith best regards to: Dr.M.Mokhtari
Embryo Implantation
What is Embryo Implantation ?
Preimplantation
Embryo- Hatching use of lytic factors
Uterus ( implantation window)-Thickness of endometrial wall- growth of secretory glands 7 days after ovulation- produce of decidual cell 9 to 10 days after ovulation- produce of pinopodes for endocytose - secret of progesterone
Pinopodes
In human are almost on non- villi
Surface of endometrium.
Have mitochondria and glycogen. Produce because of progesterone secreting.
They have villi on their surface that is
Perfect to close the trophoblast to endometrium.
Integrin on pinopodes and muc1 on endometr will help to implantation
Decidualization
EdemaPlace for natural killerSource of nutrients for embryoControl the growth of embryoImmune actionsControl the maternal vesseln system Secret some factors for develop of placentaGrowth factors are important for decidalization10% of gene expression in decidualization is in control of embryo( like EPCR)
Effecter factors in Implantation
Hormones(estrogen, progesterone, prostaglandin)
Growth factors
Cytokines
LIF
Implantation
appositio
n
locationadhesio
n
Blastocyst attach to endometriumwith L-selectin& CCR2, CCR5
Invasion
Breaching of trophoblast
Blastocyst
Early placental development
Cyncytiotrophoblast
Syncytiotrophobalst in Endometrium
The End
Power by: M.Zendehboudi
By: A.AbdeyazdanWith best regards to: Dr.M.Mokhtari
Embryo Implantation