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31st October, 2014 Volume No.: 38 Issue No.: 04

Vision

TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BAS

LEARNING AND PRACTICE

ontentsMessage from PRINCIPAL

Editorial board

Historical article

News Update

Knowledge based Article

Disease Related Breaking

News

Upcoming Events

Drugs Update

Campus NewsStudent’s Section

Editor’s Note

Archive

GNIPST Photo Gallery

or your comments/contribution

For ack-Issues, 

ailto:gnipstbulletin@gmail.com 

GURU NANAK INSTITUTE OF PHARMACEUTICAL

SCIENCE AND TECHNOLOGY

W e bs i t e : ht t p:  /   /  gni ps t. a c. i n 

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MESSAGE FROM PRINCIPAL 

" It can happen. It does happen.

 But it can't happen if you quit ." Lauren Dane.

‘We are what we repeatedly do.

 Excellence then is not an act, but a habit .’ Aristotle

It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank tlast year’s editors and congratulate the newly selected editors for the current year.

Our first consideration is always in the best interest of the students. Our goal is to promote academexcellence and continuous improvement.

I believe that excellence in education is aided by creating a learning environment in which all learners asupported in maximizing their potential and talents. Education needs to focus on personalized learni

and instruction, while promoting an education system that is impartial, universally accessible, and meeti

the needs of all students.

It is of paramount importance that our learners have sufficient motivation and encouragement in order achieve their aims. We are all very proud of you, our students, and your accomplishments and loo

forward to watching as you put your mark on the profession in the years ahead.

The call of the time is to progress, not merely to move ahead.  Our progressive Management is looki

forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken

this direction and fruits of these efforts will be received by our students in the near future. Our Teache

are committed and dedicated for the development of the institution by imparting their knowledge and pl

the role of facilitator as well as role model to our students.

The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positi

challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holist

needs of our students.

I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of t

opportunities and meet the challenges with purpose and determination.

Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us

this path.

My best wishes to all.

Dr. A. Sengupta

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individuals with myasthenia gravis and Parkinson's. Theimpact of vitamin D deficiency and supplementation onfunction in other neurologic conditions has yet to be

explored.  Digital Therapist: Computer program analyzes

speech, mental health: (31st October, 2014)A program that analyzes your speech and uses it to gaininformation about your mental health could soon be feasible,thanks in part to new research showing that certain vocal featureschange as patients’ feelings of depression worsen.

 Researchers probe link between newborn health,

vitamin A: (30th  October, 2014)The impact vitamin A has on newborns is virtually unknown, butnutrition researchers have published two papers that may providea framework for future investigations of the vitamin and neonatalhealth.

 Unlocking the secrets of pulmonary hypertension:

(30th  October, 2014)

A protein that plays a critical role in metabolism, the process bywhich the cell generates energy from foods, is important for thedevelopment of pulmonary hypertension, a deadly disease.Pulmonary hypertension is caused by the narrowing of the bloodvessels in the lung, due to excessive growth of cells in the bloodvessel wall. The cells grow in number until they obstruct thevessels, causing the heart to struggle pushing blood through thelungs to the point where the heart fails and the patient dies.

 Doubt cast over air pollution link betweenchildhood leukemia, power lines: (30th  October,

2014)Researchers from the UK have called into question a theorysuggesting that a previously reported risk of leukemia among

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children born close to overhead power lines could be caused by analteration to surrounding air pollution. 

 Scientists trigger self-destruct switch in lung

cancer cells: (30th

  October, 2014)Scientists have found a drug combination that can trigger the self-destruct process in lung cancer cells - paving the way for newtreatments, according to research. "There's an urgent need to savemore lives from lung cancer and we hope these findings will oneday lead to effective new treatments to help lung cancer patientsand potentially those with other cancer types too," authors noted.

 Heart's own immune cells can help it heal: (30th 

October, 2014)The heart holds its own pool of immune cells capable of helping itheal after injury, according to new research. In a mouse model ofheart failure, the researchers showed that blocking the bonemarrow's macrophages from entering the heart protects theorgan's beneficial pool of macrophages, allowing them to remain inthe heart, where they promote regeneration and recovery. Thefindings may have implications for treating heart failure in

humans. Genetic factors behind surviving or dying from

Ebola shown in mouse study: (30th  October,

2014)A newly developed mouse model suggests that genetic factors arebehind the mild-to-deadly range of responses to the Ebola virus.The frequency of different manifestations of the disease across thelines of these mice are similar in variety and proportion to thespectrum of clinical disease observed in the 2014 West Africanoutbreak. The new mouse model might be useful in testingcandidate therapeutics and vaccines for Ebola, and in findinggenetic markers for susceptibility and resistance to the disease. 

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 High-intensity sound waves may aid regenerative

medicine: (30th  October, 2014)Researchers have developed a way to use sound to create cellular

scaffolding for tissue engineering, a unique approach that couldhelp overcome one of regenerative medicine’s significant obstacles.

 Making lab-grown tissues stronger: (30th 

October, 2014)Lab-grown tissues could one day provide new treatments forinjuries and damage to the joints, including articular cartilage,tendons and ligaments. Cartilage, for example, is a hard materialthat caps the ends of bones and allows joints to work smoothly.

Biomedical engineers are exploring ways to toughen up engineeredcartilage and keep natural tissues strong outside the body. 

For detail mail to editor 

KNOWLEDGE BASED ARTICLE

EncephalitisEncephalitis is inflammation of the brain tissue. Most cases are

caused by viral infections. In rare cases it can also be caused by

bacteria.

There are two main types of encephalitis—primary and secondary.

Primary encephalitis is when a virus directly infects the brain and

spinal cord. Secondary encephalitis is when an infection that starts

elsewhere travels to brain. 

This disease is rare. According to the Centers for Disease Control,

encephalitis occurs in one of every 2,000,000 people. Most people

who contract it are young children, individuals over 65, or those

with weak immune system.

Though rare, the disease is very serious—severe cases can cause

death.

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Causes:

The most common virus that causes encephalitis is herpes simplex .

Usually the herpes  virus travels via a nerve to the skin. There it

causes a cold sore. In rare cases, the virus travels to the brain. Thisform of encephalitis will often affect the temporal lobe—the part of

the brain that controls memory and speech. It can also affect

the frontal lobe—which affects emotions and behavior. Herpes

encephalitis can cause severe damage.

Other common viruses that can cause encephalitis include:

• mumps

•

Epstein-Barr virus• HIV

• cytomegalovirus (CMV)Childhood Viruses

The childhood viruses that used to commonly cause encephalitis

are now preventable by vaccines. Therefore, these types of 

encephalitis are rare.

Some childhood viruses that can cause encephalitis include:

• Chicken pox (very rare)

• Measles. According to BBC health, measles causes encephalitis in

approximately one out of every 1,000 cases. In most cases, the

condition is mild. However 20 percent of those affected will have

long-term nerve damage. Up to 10 percent of cases are fatal.

• Rubella. Approximately one in 5,000 rubella patients develop

encephalitis. It is fatal up to 20 percent of the time.

Arboviruses

Arboviruses are viruses carried by insects. The disease they cause

depends on the type of insect and what viruses they carry.

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• California encephalitis is transmitted by mosquito bites. It is also

known as Lacrosse encephalitis. It mainly affects children. It has

few to no symptoms.

• St. Louis encephalitis occurs in the rural Midwest and southernstates. It is generally mild. However, in people over 60, there is a 30

percent mortality rate.

• West Nile is most often found in Africa and the Middle East.

However, it can occur in the US. West Nile is usually relatively

mild. It can be fatal among older individuals and those with

weakened immune systems.

•

Colorado encephalitis is also called  Colorado tick fever.  It istransmitted by the female wood tick.

• Eastern equine encephalitis is spread by mosquitoes. It affects both

humans and horses. It is often mild but it does have a two percent

mortality rate.

• Kyasanur forest disease is transmitted by tick bites.  It can also be

transmitted by drinking raw milk from goats, sheep, or cows. It

has a one to two percent mortality rate. People most at risk arehunters, campers, forest workers, and farmers.Risk Factors:

The groups most at risk of encephalitis are:

• older individuals

• children under 1 year of age

• people with weakened immune systems.

Living in an area with high mosquito or tick populations also puts

you at risk. So does participating in outdoor activities when

insects are present.Symptoms:

The symptoms of encephalitis can range from mild to severe. Each

type can have its own particular set of symptoms.

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Mild symptoms include:

• fever

• headache

• neck stiffness• lethargy

• general feeling of being unwell

• headache will continue to get more severe

• vomiting

Severe symptoms include:

• very high fever

•

confusion• drowsiness

• hallucinations

• slower movements

• coma

• seizures

• irritability

•

light sensitivity• unconsciousness

• severe dementia

The symptoms in very young children are different.

• vomiting

• bulging fontanel (soft spot in the scalp)

• non-stop crying

•

body stiffness• lack of appetite

Diagnosis:

If encephalitis is suspected, the following tests may be used:

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Spinal Tap Or Lumbar Puncture:

In this test, doctor will collect a sample of  spinal fluid. The sample

is then tested for signs of infection

Brain Imaging With CT Scan Or MRI:These tests detects changes in brain structure. They can rule out

other possible explanations for symptoms, such as a tumor

or stroke. Electroencephalograph (EEG):

An EEG uses electrodes attached to the scalp to record brain

activity.Blood Tests:

Blood testing can reveal signs of a viral infection.Brain Biopsy:

In a biopsy, doctor will remove small samples of brain to test for

infection. This test is rarely performed. There is a high risk of side

effects. It is usually only used if doctors cannot tell what is causing

the brain swelling and treatments are not working.Treatment:

Anti-viral medications are effective for treating herpesencephalitis. However, they have not yet been shown to work for

other forms. Instead, treatment often focuses on relieving

symptoms, using:

• pain killers

• corticosteroids (to reduce brain inflammation)

• mechanical ventilation, or breathing treatments

• lukewarm sponge baths• anticonvulsants

• sedatives (for seizures,  restlessness, aggressiveness, and 

irritability)

• rest

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• fluids (IV fluids are sometimes necessary)

Sometimes hospitalization is needed to deal with brain swelling

and seizures.

  Jeenatara Begum

Assistant Professor

GNIPST

DISEASE RELATED BREAKING NEWS 

 Human infection with avian influenza A(H7N9)

virus – China: (29th

  October, 2014)On 19 October 2014, the National Health and Family PlanningCommission of China notified WHO of 2 additional laboratory-confirmed cases of human infection with avian influenza A(H7N9)virus, including 1 death. Read more

UPCOMING EVENTS

 5th

 International Conference on Stem Cells and Cancer 2014, JNUConvention Centre, New Delhi, India from 8-10 November, 2014

DRUGS UPDATES 

 FDA Approves Xigduo XR (dapagliflozin and

metformin hydrochloride) for Type 2 Diabetes:

(30th October, 2014)AstraZeneca announced that the U.S. Food and DrugAdministration has approved once-daily Xigduo XR (dapagliflozinand metformin hydrochloride extended-release) for the treatmentof adults with type 2 diabetes. Read more

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CAMPUS NEWS 

 Today the students of GNIPST have participated in the ‘Run forUnity’ as a mark of tribute to the efforts of the country's firstHome Minister Sardar Vallabhbhai Patel. 

 Congratulation to the winner of Cricket Tournament-B.Pharm 3rdyear, 2014Runner up team-B.Sc and BHM, 2014

 Congratulation to the highest run scorer of Cricket Tournament-Tanmoy Das Biswas, B.Pharm 3rd year, 2014

 Congratulation to the highest wicket taker of CricketTournament-Subhodip Das, B.Pharm 3rd year, 2014

 Congratulation to the winner of Carom Tournament (Boys)-Sk. Abdul Salam, B.Pharm 2nd  year, 20141st Runner up-Subhayan Dutta, M.Sc (Biotechnology Department)

2nd year, 2014

2nd Runner up-Nirupan Gupta, B.Pharm 1st year, 2014

 Congratulation to the winner of Carom Tournament (Girls)-Aishwarya Datta, B.Pharm 2nd  year, 20141st Runner up-Krishnakali Basu, B.Pharm 3rd  year, 2014

2nd Runner up-Rituparna Das, B.Pharm 3rd  year, 2014 Congratulation to the winner of Chess Tournament (Boys)-

Basab Brata Dey, M.Sc (Biotechnology Department) 2nd  year, 20141st Runner up-Ankit Chowdhury, B.Pharm 1st year, 2014

2nd Runner up-Smaranjeet Banik, B.Pharm 3rd  year, 2014

 Congratulation to the winner of Chess Tournament (Girls)-Rituparna Das, B.Pharm 3rd  year, 20141st Runner up-Varsa Srivastav, B.Sc(Bioptechnology Department)

1st year, 2014

2nd Runner up- Krishnakali Basu, B.Pharm 3rd  year, 2014

 The GNIPST Cricket Tournament, Carom Tournament and Chess

Tournament was held on 21st and 22nd   October, 2014.

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 The Cultural Programme on Bijoya Dashami and Kali Puja was

held on 20th October, 2014

 An exhibition on Photography and Painting was held on 20th 

October, 2014 Congratulation to the winner of Football Tournament-B.Pharm

3rd year, 2014Runner up team-B.Pharm final year, 2014

 Congratulation to the winner of Table Tennis Tournament-Krishnakali Basu, B.Pharm 3rd year, 20141st Runner up-Aindrila Bhowmick, B.Pharm 2nd year, 2014

2nd Runner up-Sayani Banerjee, B.Pharm 2nd year, 2014

 The GNIPST Football Tournament (for male students) and Table

Tennis tournament (for female students) was held on 25th and

26th September, 2014.

 On 5th  September, 2014 the students of GNIPST have arranged a

wonderful Teacher’s Day Programme. On behalf of all the teachers

of GNIPST I would like to thank our beloved students.

 The Fresher’s welcome programme was held on 14th August, 2014.

Welcome 1st year students.

 We congratulate the following M.Pharm. final year students who

have made their positions in different pharmaceutical companies.

Anirban Banerjee (Emami Ltd.)

Mahender Roy (Stadmed private Ltd.)

 We congratulate the following B.Pharm. final year students for

their success.

Samadrita Mukherjee (Abbott India Ltd.)Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)

Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)

Avishek Naskar (Glaxo SmithKline-Marketing)

Bappaditya Manik (USV Limited)

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Sarbani Das (Nutri Synapzz-Marketing)

Ankita Roy (Nutri Synapzz-Marketing)

Rahul Mitra (B M Pharmaceuticals-Production)

 The following B.Pharm. final year students have qualified, GPAT-2014. We congratulate them all.

Utsha Sinha

Satarupa Bhattacharya

Sandipan Sarkar

Purbali Chakraborty

 Reminiscence, 2014(GNIPST Reunion) was held in College

campus on 2

nd 

 February,2014. 

 1st  Annual Sports of GNIPST was held on 3rd   February,2014 in

College campus ground.

 An industrial tour and biodiversity tour was conducted in Sikkim

for B.Pharm and B.Sc. students under the supervision of Mr. Asis

Bala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.

 B.Pharm 3rd   year won the GNIPST Football Champions trophy,

2013. B.Pharm 3

rd 

 year won the final match 1-0 against B.Pharm 2

nd 

 year. Deep Chakraborty was the only scorer of the final.

STUDENTS’ SECTION

WHO CAN ANSWER FIRST????  

Dr. S. K. Burman established which 

 pharmaceutical company?

Kavli prize is awarded in which 

discipline?

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Answer of Previous Issue’s Questions

 A) Santosh Trophy

B) Football

 Identify the person

Answer of Previous Issue’s Image

Magnus Carlsen 

Send your thoughts/

Quiz/Puzzles/games/write-ups or any other

contributions for Students’ Section

answ ers of this Section at

 gnipstbulletin@gmail.com

EDITOR’S NOTE

It is a great pleasure for me to publish the 4th

 issue of 38th

 Volume

of GNIPST BULLETIN. All the followers of GNIPST BULLETIN

are able to avail the bulletin through  facebook account ‘GNIPST

bulletin’ I am very much thankful to all the GNIPST members and

readers who are giving their valuable comments, encouragements

and supports. I am also thankful to Dr. Abhijit Sengupta, Director

of GNIPST for his valuable advice and encouragement. Special

thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar

and Mr. Soumya Bhattacharya for their kind co-operation and

technical supports. Thank you Mr. Soumya Bhattacharya for the

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questionnaires of the student section. An important part of the

improvement of the bulletin is the contribution of the readers. You

are invited to send in your write ups, notes, critiques or any kind of

contribution for the forthcoming special and regular issue.

ARCHIVE

 GNIPST organized a garment distribution programme  on 28th 

September, 2013 at Dakshineswar Kali Temple and Adyapith,

Kolkata. On this remarkable event about hundred people have

received garments. More than hundred students and most of the

faculties participated on that day with lot of enthusiasm.

 GNIPST celebrated World Heart Day (29th  September)  and

Pharmacist’s Day (25th September) on 25th and 26th September,

2013 in GNIPST Auditorium. A seminar on ‘Violence against

woman’ and ‘female foeticide’ was held on GNIPST Auditorium on

25th  September organized by JABALA Action Research

Organization. On 26th September an intra-college Oral and Poster

presentation competition related to World Pharmacist’s day and

Heart day was held in GNIPST. Ms. Purbali Chakraborty  of

B.Pharm 4th  year won the first prize in Oral Presentation. The

winner of Poster presentation was the group of Ms. Utsa Sinha,

Mr. Koushik Saha and Mr. Niladri Banerjee (B.Pharm 4th year). A

good number of students have participated in both the

competition with their valuable views.

 Teacher’s day was celebrated on 5th September, 2013 by the

students of GNIPST in GNIPST Auditorium. 

 Azalea exotic flower )  , the fresher welcome programme for

newcomers of GNIPST in the session 2013-14 was held on 8th 

August in GNIPST Auditorium.

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 One day seminar cum teachers’ development programme for

school teachers on the theme of “Recent Trends of Life Sciences

in Higher Education”  organized by GNIPST held on 29th  June,

2013 at GNIPST auditorium. The programme was inaugurated byProf . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy

Director of JIS Group and Dr. Abhijit Sengupta, Director cum

Principal of GNIPST with lamp lighting. The programme started

with an opening song performed by the B.Pharm students of this

institute. The seminar consists of a series of lectures, video

presentations and poster session. On the pre lunch session 4

lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata

Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty

respectively. On their presentation the speakers enlighten the

recent development of Pharmacy, Genetics and Microbiology and

their correlation with Life Sciences. On the post lunch session, Ms.

Saini Setua and Ms. Sanchari Bhattacharjee explained the recent

development and career opportunities in Biotechnology and

Hospital Management. The programme was concluded with

valedictory session and certificate distribution.About 50 Higher secondary school teachers from different

schools of Kolkata and North& South 24 Parganas district of West

Bengal participated in this programme. A good interactive session

between participants and speakers was observed in the seminar.

The seminar was a great success with the effort of faculties, staffs

and students of our Institute. It was a unique discussion platform

for school teachers and professional of the emerging and newerbranches of Life Science.

The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th June, 2012. The program started with

a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural

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Products, JU on the skill to write a good manuscript for

publication in impact journals. It was followed by nearly two hour

long discussion among more than thirty participants on different

aspects of pharmacy education. Five nonmember participants

applied for membership on that very day.

GNIPST is now approved by AICTE and affiliated to WBUT for

conducting the two years’ post graduate course (M.Pharm)

in P H A R M A C O L O G Y . The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to

120.

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-13to

GNIPST as per the details below:

a. Beneficiary Institution:  Guru Nanak Institution of Pharmaceutical

Science & Technology.

b. Principal Investigator: Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- only

d. Approved duration: 3 years

e. Title of the project:  Screening and identification of potential

medicinal plant of Purulia & Bankura districts of West Bengal

with respect to diseases such as diabetes, rheumatism, Jaundice,

hypertension and developing biotechnological tools for enhancing

bioactive molecules in these plants.

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